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Search results 1 to 100 out of 172 for Ksr1

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0.04s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: McKay MM
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Signaling dynamics of the KSR1 scaffold complex.
Volume: 106
Issue: 27
Pages: 11022-7
Publication
First Author: Razidlo GL
Year: 2009
Journal: J Biol Chem
Title: KSR1 is required for cell cycle reinitiation following DNA damage.
Volume: 284
Issue: 11
Pages: 6705-15
Publication
First Author: Müller J
Year: 2000
Journal: Mol Cell Biol
Title: Identification of B-KSR1, a novel brain-specific isoform of KSR1 that functions in neuronal signaling.
Volume: 20
Issue: 15
Pages: 5529-39
Publication
First Author: Ritt DA
Year: 2007
Journal: Curr Biol
Title: CK2 Is a component of the KSR1 scaffold complex that contributes to Raf kinase activation.
Volume: 17
Issue: 2
Pages: 179-84
Publication
First Author: Kortum RL
Year: 2004
Journal: Mol Cell Biol
Title: The molecular scaffold KSR1 regulates the proliferative and oncogenic potential of cells.
Volume: 24
Issue: 10
Pages: 4407-16
Publication
First Author: Giurisato E
Year: 2009
Journal: Mol Cell Biol
Title: The mitogen-activated protein kinase scaffold KSR1 is required for recruitment of extracellular signal-regulated kinase to the immunological synapse.
Volume: 29
Issue: 6
Pages: 1554-64
Publication
First Author: Llobet D
Year: 2011
Journal: Am J Pathol
Title: KSR1 is overexpressed in endometrial carcinoma and regulates proliferation and TRAIL-induced apoptosis by modulating FLIP levels.
Volume: 178
Issue: 4
Pages: 1529-43
Publication
First Author: Canal F
Year: 2011
Journal: FASEB J
Title: Compartmentalization of the MAPK scaffold protein KSR1 modulates synaptic plasticity in hippocampal neurons.
Volume: 25
Issue: 7
Pages: 2362-72
Publication
First Author: Basu SK
Year: 2018
Journal: Cancer Res
Title: Oncogenic RAS-Induced Perinuclear Signaling Complexes Requiring KSR1 Regulate Signal Transmission to Downstream Targets.
Volume: 78
Issue: 4
Pages: 891-908
Publication
First Author: Goettel JA
Year: 2011
Journal: Exp Cell Res
Title: KSR1 is a functional protein kinase capable of serine autophosphorylation and direct phosphorylation of MEK1.
Volume: 317
Issue: 4
Pages: 452-63
Publication
First Author: Germino EA
Year: 2018
Journal: PLoS One
Title: Homozygous KSR1 deletion attenuates morbidity but does not prevent tumor development in a mouse model of RAS-driven pancreatic cancer.
Volume: 13
Issue: 3
Pages: e0194998
Publication
First Author: Filbert EL
Year: 2010
Journal: Eur J Immunol
Title: Kinase suppressor of Ras 1 is required for full ERK activation in thymocytes but not for thymocyte selection.
Volume: 40
Issue: 11
Pages: 3226-34
Publication
First Author: Fusello AM
Year: 2006
Journal: J Immunol
Title: The MAPK scaffold kinase suppressor of Ras is involved in ERK activation by stress and proinflammatory cytokines and induction of arthritis.
Volume: 177
Issue: 9
Pages: 6152-8
Publication
First Author: Zhang Y
Year: 2011
Journal: Nat Med
Title: Kinase suppressor of Ras-1 protects against pulmonary Pseudomonas aeruginosa infections.
Volume: 17
Issue: 3
Pages: 341-6
Publication
First Author: Shalin SC
Year: 2006
Journal: Neuron
Title: Kinase suppressor of Ras1 compartmentalizes hippocampal signal transduction and subserves synaptic plasticity and memory formation.
Volume: 50
Issue: 5
Pages: 765-79
Publication
First Author: Le Borgne M
Year: 2013
Journal: PLoS One
Title: Kinase suppressor of Ras 1 is not required for the generation of regulatory and memory T cells.
Volume: 8
Issue: 2
Pages: e57137
Publication
First Author: Gramling MW
Year: 2012
Journal: Cell Death Differ
Title: Suppression of Ras/Mapk pathway signaling inhibits Myc-induced lymphomagenesis.
Volume: 19
Issue: 7
Pages: 1220-7
Publication
First Author: Chen M
Year: 2011
Journal: Exp Hematol
Title: Kinase suppressor of Ras (KSR1) modulates multiple kit-ligand-dependent mast cell functions.
Volume: 39
Issue: 10
Pages: 969-76
Publication
First Author: Kortum RL
Year: 2005
Journal: Mol Cell Biol
Title: The molecular scaffold kinase suppressor of Ras 1 (KSR1) regulates adipogenesis.
Volume: 25
Issue: 17
Pages: 7592-604
Publication
First Author: Müller J
Year: 2003
Journal: EMBO J
Title: Functional analysis of C-TAK1 substrate binding and identification of PKP2 as a new C-TAK1 substrate.
Volume: 22
Issue: 17
Pages: 4431-42
Publication
First Author: Salerno M
Year: 2005
Journal: Mol Cell Biol
Title: Nm23-H1 metastasis suppressor expression level influences the binding properties, stability, and function of the kinase suppressor of Ras1 (KSR1) Erk scaffold in breast carcinoma cells.
Volume: 25
Issue: 4
Pages: 1379-88
Publication
First Author: Fernández IF
Year: 2012
Journal: Cell Mol Life Sci
Title: VRK2 anchors KSR1-MEK1 to endoplasmic reticulum forming a macromolecular complex that compartmentalizes MAPK signaling.
Volume: 69
Issue: 22
Pages: 3881-93
Publication
First Author: Kortum RL
Year: 2006
Journal: Mol Cell Biol
Title: The molecular scaffold kinase suppressor of Ras 1 is a modifier of RasV12-induced and replicative senescence.
Volume: 26
Issue: 6
Pages: 2202-14
Publication
First Author: McKay MM
Year: 2011
Journal: Curr Biol
Title: RAF inhibitor-induced KSR1/B-RAF binding and its effects on ERK cascade signaling.
Volume: 21
Issue: 7
Pages: 563-8
Publication
First Author: Sibilski C
Year: 2013
Journal: J Biol Chem
Title: Tyr728 in the kinase domain of the murine kinase suppressor of RAS 1 regulates binding and activation of the mitogen-activated protein kinase kinase.
Volume: 288
Issue: 49
Pages: 35237-52
Publication
First Author: Yan F
Year: 2004
Journal: J Clin Invest
Title: Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation.
Volume: 114
Issue: 9
Pages: 1272-80
Publication
First Author: Lozano J
Year: 2003
Journal: Cancer Res
Title: Deficiency of kinase suppressor of Ras1 prevents oncogenic ras signaling in mice.
Volume: 63
Issue: 14
Pages: 4232-8
Publication
First Author: Dougherty MK
Year: 2009
Journal: Mol Cell
Title: KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals.
Volume: 34
Issue: 6
Pages: 652-62
Publication
First Author: Fernandez MR
Year: 2012
Journal: Mol Cell Biol
Title: Kinase suppressor of Ras 2 (KSR2) regulates tumor cell transformation via AMPK.
Volume: 32
Issue: 18
Pages: 3718-31
Publication
First Author: Shen CH
Year: 2013
Journal: Mol Cell
Title: Phosphorylation of BRAF by AMPK impairs BRAF-KSR1 association and cell proliferation.
Volume: 52
Issue: 2
Pages: 161-72
Publication
First Author: Hu J
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF.
Volume: 108
Issue: 15
Pages: 6067-72
Publication
First Author: Kortum RL
Year: 2014
Journal: Mol Cell Biol
Title: Caveolin-1 is required for kinase suppressor of Ras 1 (KSR1)-mediated extracellular signal-regulated kinase 1/2 activation, H-RasV12-induced senescence, and transformation.
Volume: 34
Issue: 18
Pages: 3461-72
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Stewart S
Year: 1999
Journal: Mol Cell Biol
Title: Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization.
Volume: 19
Issue: 8
Pages: 5523-34
Publication
First Author: Smith FD
Year: 2010
Journal: Nat Cell Biol
Title: AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade.
Volume: 12
Issue: 12
Pages: 1242-9
Publication
First Author: Therrien M
Year: 1995
Journal: Cell
Title: KSR, a novel protein kinase required for RAS signal transduction.
Volume: 83
Issue: 6
Pages: 879-88
Publication
First Author: Nguyen A
Year: 2002
Journal: Mol Cell Biol
Title: Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo.
Volume: 22
Issue: 9
Pages: 3035-45
GXD Expression      
Probe: MGI:5285974
Assay Type: Western blot
Annotation Date: 2011-09-21
Strength: Absent
Sex: Female
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5285980
Age: postnatal week 6
Specimen Label: Heart
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5285974
Assay Type: Western blot
Annotation Date: 2011-09-21
Strength: Absent
Sex: Female
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5285980
Age: postnatal week 6
Specimen Label: Spleen
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:5285974
Assay Type: Western blot
Annotation Date: 2011-09-21
Strength: Absent
Sex: Female
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5285980
Age: postnatal week 6
Specimen Label: Thymus
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:5285974
Assay Type: Western blot
Annotation Date: 2011-09-21
Strength: Present
Sex: Female
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5285980
Age: postnatal week 6
Specimen Label: Cerebral cortex
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5285974
Assay Type: Western blot
Annotation Date: 2011-09-21
Strength: Present
Sex: Female
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5285980
Age: postnatal week 6
Specimen Label: Cerebellum
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5285974
Assay Type: Western blot
Annotation Date: 2011-09-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:5285980
Age: postnatal week 6
Specimen Label: Ovary
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5285974
Assay Type: Western blot
Annotation Date: 2011-09-21
Strength: Absent
Sex: Female
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5285980
Age: postnatal week 6
Specimen Label: Kidney
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:5285974
Assay Type: Western blot
Annotation Date: 2011-09-21
Strength: Present
Sex: Female
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:5285980
Age: postnatal week 6
Specimen Label: Bladder
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5285974
Assay Type: Western blot
Annotation Date: 2011-09-21
Strength: Absent
Sex: Female
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:5285980
Age: postnatal week 6
Specimen Label: Intestine
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:5285974
Assay Type: Western blot
Annotation Date: 2011-09-21
Strength: Present
Sex: Female
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5285980
Age: postnatal week 6
Specimen Label: Lung
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5285974
Assay Type: Western blot
Annotation Date: 2011-09-21
Strength: Absent
Sex: Female
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:5285980
Age: postnatal week 6
Specimen Label: Eye
Detected: false
Specimen Num: 11
GXD Expression      
Probe: MGI:5285974
Assay Type: Western blot
Annotation Date: 2011-09-21
Strength: Absent
Sex: Female
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5285980
Age: postnatal week 6
Specimen Label: Liver
Detected: false
Specimen Num: 12
GXD Expression      
Probe: MGI:5285975
Assay Type: RT-PCR
Annotation Date: 2011-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:5285981
Age: embryonic day 10.5
Specimen Label: E10.5 embryo
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5285975
Assay Type: RT-PCR
Annotation Date: 2011-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5285981
Age: postnatal adult
Specimen Label: Cerebral cortex
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5285975
Assay Type: RT-PCR
Annotation Date: 2011-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5285981
Age: postnatal adult
Specimen Label: Cerebellum
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5285975
Assay Type: RT-PCR
Annotation Date: 2011-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5285981
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5285975
Assay Type: RT-PCR
Annotation Date: 2011-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5285981
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5285975
Assay Type: RT-PCR
Annotation Date: 2011-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5285981
Age: postnatal adult
Specimen Label: Thymus
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5285975
Assay Type: RT-PCR
Annotation Date: 2011-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5285981
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5285975
Assay Type: RT-PCR
Annotation Date: 2011-09-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5285981
Age: postnatal adult
Specimen Label: Liver
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:5285975
Assay Type: RT-PCR
Annotation Date: 2011-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5285981
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5285975
Assay Type: RT-PCR
Annotation Date: 2011-09-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5285981
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:5285975
Assay Type: RT-PCR
Annotation Date: 2011-09-21
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:5285981
Age: postnatal adult
Specimen Label: Uterus
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:5285975
Assay Type: RT-PCR
Annotation Date: 2011-09-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:5285981
Age: postnatal adult
Specimen Label: Ovary
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:5285975
Assay Type: RT-PCR
Annotation Date: 2011-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:5285981
Age: postnatal adult
Specimen Label: Bladder
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:5285975
Assay Type: RT-PCR
Annotation Date: 2011-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1925228
Stage: TS28
Assay Id: MGI:5285981
Age: postnatal adult
Specimen Label: Large intestine
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:5285975
Assay Type: RT-PCR
Annotation Date: 2011-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:5285981
Age: postnatal adult
Specimen Label: Small intestine
Detected: true
Specimen Num: 16
GXD Expression      
Probe: MGI:5285975
Assay Type: RT-PCR
Annotation Date: 2011-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:5285981
Age: postnatal adult
Specimen Label: Stomach
Detected: true
Specimen Num: 17
GXD Expression      
Probe: MGI:5285974
Assay Type: Western blot
Annotation Date: 2011-09-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5286064
Age: postnatal
Specimen Label: Testis
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5285974
Assay Type: Immunohistochemistry
Annotation Date: 2011-09-21
Strength: Strong
Sex: Male
Emaps: EMAPS:3570728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5285977
Age: postnatal week 6
Note: Localization is primarily at the plasma membrane region.
Specimen Label: 3E
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5285974
Assay Type: Immunohistochemistry
Annotation Date: 2011-09-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1640517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5285977
Age: embryonic day 10.5
Specimen Label: 4B
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5285974
Assay Type: Immunohistochemistry
Annotation Date: 2011-09-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1640517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5285977
Age: embryonic day 10.5
Specimen Label: 4C
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:5285974
Assay Type: Immunohistochemistry
Annotation Date: 2011-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160699
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:5285977
Age: embryonic day 6.5
Specimen Label: 4A
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5285974
Assay Type: Immunohistochemistry
Annotation Date: 2011-09-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1674817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5285977
Age: embryonic day 10.5
Specimen Label: 4B
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5285974
Assay Type: Immunohistochemistry
Annotation Date: 2011-09-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1674817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5285977
Age: embryonic day 10.5
Specimen Label: 4C
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:5285974
Assay Type: Immunohistochemistry
Annotation Date: 2011-09-21
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5285977
Age: postnatal week 6
Note: Expression is in the cell bodies of the pyramidal neurons.
Specimen Label: 3A
Detected: true
Specimen Num: 1