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Search results 1 to 100 out of 107 for Kti12

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Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
112970 | KTI12
Type: gene
Organism: human
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Gene
549045 | kti12
Type: gene
Organism: frog, western clawed
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Gene
685656 | Kti12
Type: gene
Organism: rat
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Gene
736456 | KTI12
Type: gene
Organism: chimpanzee
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Gene
538901 | KTI12
Type: gene
Organism: cattle
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Gene
100688398 | KTI12
Type: gene
Organism: dog, domestic
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Gene
424637 | KTI12
Type: gene
Organism: chicken
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Gene
751662 | kti12
Type: gene
Organism: zebrafish
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Gene
712824 | KTI12
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR045106 | Kti12
Type: Family
Description: Budding yeast Protein Kti12 associates with Elongator complex, a six-subunit complex involved in tRNA modification [, ]. Kti12 is not a structural subunit but may play a regulatory role in Elongator function [, , , ]. It has been shown that Kti12 is associated with chromatin throughout the genome, even in non-transcribed regions and in the absence of Elongator []. It is required for an early step in synthesis of 5-methoxycarbonylmethyl (mcm5) and 5-carbamoylmethyl (ncm5) groups present on uridines at the wobble position in tRNA [].In plants, proteins from this family have been related to tRNA wobble uridine modification, stress response and drought stress tolerance [].
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Protein Coding Gene
MGI:1923547 | Kti12
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
28872616 | -
 
First Author: Mehlgarten C
Year: 2017
Journal: Toxins (Basel)
Title: Use of a Yeast tRNase Killer Toxin to Diagnose Kti12 Motifs Required for tRNA Modification by Elongator.
Volume: 9
Issue: 9
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Protein
Q9D1R2
Organism: Mus musculus/domesticus
Length: 351  
Fragment?: false
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Publication
15772087 | -
First Author: Petrakis TG
Year: 2005
Journal: J Biol Chem
Title: Physical and functional interaction between Elongator and the chromatin-associated Kti12 protein.
Volume: 280
Issue: 20
Pages: 19454-60
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Publication
19656297 | -
First Author: Mehlgarten C
Year: 2009
Journal: Mol Microbiol
Title: Elongator function depends on antagonistic regulation by casein kinase Hrr25 and protein phosphatase Sit4.
Volume: 73
Issue: 5
Pages: 869-81
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Publication
14718557 | -
First Author: Jablonowski D
Year: 2004
Journal: Mol Biol Cell
Title: The yeast elongator histone acetylase requires Sit4-dependent dephosphorylation for toxin-target capacity.
Volume: 15
Issue: 3
Pages: 1459-69
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Publication
25569479 | -
First Author: Abdel-Fattah W
Year: 2015
Journal: PLoS Genet
Title: Phosphorylation of Elp1 by Hrr25 is required for elongator-dependent tRNA modification in yeast.
Volume: 11
Issue: 1
Pages: e1004931
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Publication
32705117 | -
First Author: Wang H
Year: 2020
Journal: Tree Physiol
Title: PtKTI12 genes influence wobble uridine modifications and drought stress tolerance in hybrid poplar.
Volume: 40
Issue: 12
Pages: 1778-1791
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Publication
11929532 | -
First Author: Fichtner L
Year: 2002
Journal: Mol Microbiol
Title: Molecular analysis of KTI12/TOT4, a Saccharomyces cerevisiae gene required for Kluyveromyces lactis zymocin action.
Volume: 43
Issue: 3
Pages: 783-91
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Protein Coding Gene
MGP_CAROLIEiJ_G0026277 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028564 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028527 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028474 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028546 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0028260 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1923547 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028986 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027696 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0028229 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0028377 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0028345 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0028478 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0028371 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0029022 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0027422 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027777 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028610 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0027246 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1697428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692148
Age: postnatal adult
Image: JAX_1373158
Specimen Label: JAX_1373158
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692148
Age: postnatal adult
Image: JAX_1373160
Specimen Label: JAX_1373160
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6692148
Age: embryonic day 12.5
Image: JAX_1470868
Specimen Label: JAX_1470868
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6692148
Age: embryonic day 12.5
Image: JAX_1470869
Specimen Label: JAX_1470869
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6692148
Age: embryonic day 12.5
Image: JAX_1470870
Specimen Label: JAX_1470870
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6692148
Age: embryonic day 12.5
Image: JAX_1470871
Specimen Label: JAX_1470871
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1842628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692148
Age: postnatal adult
Image: JAX_1373162
Specimen Label: JAX_1373162
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692148
Age: postnatal adult
Image: JAX_1373159
Specimen Label: JAX_1373159
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692148
Age: postnatal adult
Image: JAX_1373163
Specimen Label: JAX_1373163
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692148
Age: postnatal adult
Image: JAX_1373165
Specimen Label: JAX_1373165
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692148
Age: postnatal adult
Image: JAX_1373164
Specimen Label: JAX_1373164
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692148
Age: postnatal adult
Image: JAX_1373161
Specimen Label: JAX_1373161
Detected: true
Specimen Num: 11
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Publication
15769872 | -
First Author: Huang B
Year: 2005
Journal: RNA
Title: An early step in wobble uridine tRNA modification requires the Elongator complex.
Volume: 11
Issue: 4
Pages: 424-36
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Protein
Q8C992
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: false
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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UniProt Feature
UniProt Feature
Begin: 1
Description: Protein KTI12 homolog
Type: chain
End: 351
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Gene
120100689 | Kti12-ps1
Type: gene
Organism: rat
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Gene
735147 | kti12.L
Type: gene
Organism: frog, African clawed
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Allele
Kti12<+> | MGI:3583233
 
Name: KTI12 homolog, chromatin associated; wild type
Allele Type: Not Specified
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Allele
Kti12<tm1(KOMP)Vlcg> | MGI:5051058
Name: KTI12 homolog, chromatin associated; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Kti12<tm1.1(KOMP)Vlcg> | MGI:5708227
Name: KTI12 homolog, chromatin associated; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Kti12<em12Gpt> | MGI:7462182
Name: KTI12 homolog, chromatin associated; endonuclease-mediated mutation 12, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Kti12<em1Gpt> | MGI:7462183
Name: KTI12 homolog, chromatin associated; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6346471 | C57BL/6N-Kti12<tm1.1(KOMP)Vlcg>/JMmucd
Attribute String: mutant strain, coisogenic, targeted mutation
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Strain
MGI:5750781 | B6N(Cg)-Kti12<tm1.1(KOMP)Vlcg>/J
Attribute String: mutant strain, targeted mutation
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Strain
MGI:6261107 | C57BL/6N-Kti12<tm1.1(KOMP)Vlcg>/J
Attribute String: coisogenic, targeted mutation
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Strain
MGI:7469219 | C57BL/6JGpt-Kti12<em12Gpt>/Gpt
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7469220 | C57BL/6JGpt-Kti12<em1Gpt>/Gpt
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Kti12/Kti12
Background: C57BL/6N-Kti12/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kti12/Kti12<+>
Background: C57BL/6N-Kti12/J
Zygosity: ht
Has Mutant Allele: true
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Protein Domain
IPR013641 | KTI12/PSTK
Type: Family
Description: Kti12 associates with Elongator complex, a six-subunit histone acetytransferase complex that functions with the elongating form of RNA polymerase II during transcription []. It is not a structural subunit but may play a regulatory role in Elongator function []. It has been shown that Kti12 is associated with chromatin throughout the genome, even in non-transcribed regions and in the absence of Elongator []. It is required for an early step in synthesis of 5-methoxycarbonylmethyl (mcm5) and 5-carbamoylmethyl (ncm5) groups present on uridines at the wobble position in tRNA [].L-seryl-tRNA(Sec) kinase (PSTK) specifically phosphorylates seryl-tRNA(Sec) to O-phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis [].
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Publication
15317934 | J:92439
First Author: Carlson BA
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Identification and characterization of phosphoseryl-tRNA[Ser]Sec kinase.
Volume: 101
Issue: 35
Pages: 12848-53
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Protein
A0A140LIA4
Organism: Mus musculus/domesticus
Length: 74  
Fragment?: false
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Protein
A0A140LI89
Organism: Mus musculus/domesticus
Length: 136  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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