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Search results 1 to 100 out of 185 for Lars

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Hits by Pathway

Hits by Category

Type Details Score
Gene
416347 | LARS
Type: gene
Organism: chicken
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Transgene
MGI:6202615 | Tg(Cd3d-CD4,H2-Ea-HLA-DRA*0101,-HLA-DRB1*0401)#Lfug
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5429699 | Tg(TCROb.1A12)#Lfug
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5429697 | Tg(HLA-DR2)#Lfug
Type: transgene
Organism: mouse, laboratory
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Publication
8016129 | J:265804
First Author: Fugger L
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Expression of HLA-DR4 and human CD4 transgenes in mice determines the variable region beta-chain T-cell repertoire and mediates an HLA-DR-restricted immune response.
Volume: 91
Issue: 13
Pages: 6151-5
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Publication
24683185 | J:209975
First Author: Meza-Romero R
Year: 2014
Journal: J Immunol
Title: HLA-DRα1 constructs block CD74 expression and MIF effects in experimental autoimmune encephalomyelitis.
Volume: 192
Issue: 9
Pages: 4164-73
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Publication
20059576 | J:166417
First Author: Buenafe AC
Year: 2010
Journal: Immunology
Title: Prevention and treatment of experimental autoimmune encephalomyelitis with clonotypic CDR3 peptides: CD4(+) Foxp3(+) T-regulatory cells suppress interleukin-2-dependent expansion of myelin basic protein-specific T cells.
Volume: 130
Issue: 1
Pages: 114-24
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Protein
Q99JK2
Organism: Mus musculus/domesticus
Length: 438  
Fragment?: false
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Transgene
MGI:5922011 | Tg(tetO-TARDBP*A315T)6Lmit
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:4420242 | Tg(Thy1-APPSwe)1Lngn
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5922005 | Tg(tetO-TARDBP*A315T)#Lmit
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5922012 | Tg(tetO-TARDBP*A315T)13Lmit
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5922018 | Tg(Thy1-tTA)15Lmit
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5922017 | Tg(Thy1-tTA)6Lmit
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:4420230 | Tg(Thy1-APPSweArc)BLngn
Type: transgene
Organism: mouse, laboratory
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Publication
30814252 | J:278232
First Author: Michno W
Year: 2019
Journal: J Biol Chem
Title: Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1-40 deposition underlies plaque polymorphism in progressing Alzheimer's disease pathology.
Volume: 294
Issue: 17
Pages: 6719-6732
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Publication
31605538 | J:285316
First Author: Michno W
Year: 2020
Journal: J Neurochem
Title: Chemical imaging of evolving amyloid plaque pathology and associated Aβ peptide aggregation in a transgenic mouse model of Alzheimer's disease.
Volume: 152
Issue: 5
Pages: 602-616
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Publication
24126157 | J:212602
First Author: Lillehaug S
Year: 2014
Journal: Neurobiol Aging
Title: Brainwide distribution and variance of amyloid-beta deposits in tg-ArcSwe mice.
Volume: 35
Issue: 3
Pages: 556-64
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Publication
25089901 | J:223167
First Author: Nuruddin S
Year: 2014
Journal: PLoS One
Title: Elevated mRNA-levels of gonadotropin-releasing hormone and its receptor in plaque-bearing Alzheimer's disease transgenic mice.
Volume: 9
Issue: 8
Pages: e103607
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Publication
35833623 | J:327137
   
First Author: Åbjørsbråten KS
Year: 2022
Journal: Elife
Title: Impaired astrocytic Ca2+ signaling in awake-behaving Alzheimer's disease transgenic mice.
Volume: 11
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Publication
20615433 | J:162999
First Author: Codita A
Year: 2010
Journal: Behav Brain Res
Title: Impaired behavior of female tg-ArcSwe APP mice in the IntelliCage: A longitudinal study.
Volume: 215
Issue: 1
Pages: 83-94
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Publication
27034428 | J:234697
First Author: Lai JD
Year: 2016
Journal: Blood
Title: Concurrent influenza vaccination reduces anti-FVIII antibody responses in murine hemophilia A.
Volume: 127
Issue: 26
Pages: 3439-49
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Publication
22955884 | J:190144
First Author: Ooi JD
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis.
Volume: 109
Issue: 39
Pages: E2615-24
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Publication
23549081 | J:197610
First Author: Roth AJ
Year: 2013
Journal: J Clin Invest
Title: Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis.
Volume: 123
Issue: 4
Pages: 1773-83
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Publication
30872722 | J:276682
First Author: Jendresen C
Year: 2019
Journal: Sci Rep
Title: Systemic LPS-induced Aβ-solubilization and clearance in AβPP-transgenic mice is diminished by heparanase overexpression.
Volume: 9
Issue: 1
Pages: 4600
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Publication
25548284 | J:276782
First Author: Jendresen CB
Year: 2015
Journal: J Biol Chem
Title: Overexpression of heparanase lowers the amyloid burden in amyloid-β precursor protein transgenic mice.
Volume: 290
Issue: 8
Pages: 5053-64
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Publication
22576344 | J:223137
First Author: Klyushnenkova EN
Year: 2012
Journal: J Immunother
Title: A cytomegalovirus-based vaccine expressing a single tumor-specific CD8+ T-cell epitope delays tumor growth in a murine model of prostate cancer.
Volume: 35
Issue: 5
Pages: 390-9
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Publication
16298242 | J:105265
First Author: Lord A
Year: 2006
Journal: Neurobiol Aging
Title: The Arctic Alzheimer mutation facilitates early intraneuronal Abeta aggregation and senile plaque formation in transgenic mice.
Volume: 27
Issue: 1
Pages: 67-77
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Publication
18192084 | J:152959
First Author: Philipson O
Year: 2009
Journal: Neurobiol Aging
Title: A highly insoluble state of Abeta similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice.
Volume: 30
Issue: 9
Pages: 1393-405
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Publication
21514441 | J:171581
First Author: Lord A
Year: 2011
Journal: Am J Pathol
Title: Observations in APP bitransgenic mice suggest that diffuse and compact plaques form via independent processes in Alzheimer's disease.
Volume: 178
Issue: 5
Pages: 2286-98
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Protein
Q8BMJ2
Organism: Mus musculus/domesticus
Length: 1178  
Fragment?: false
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Publication
24227784 | J:207124
First Author: Sosa RA
Year: 2013
Journal: J Immunol
Title: The kinetics of myelin antigen uptake by myeloid cells in the central nervous system during experimental autoimmune encephalomyelitis.
Volume: 191
Issue: 12
Pages: 5848-57
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Publication
30099489 | J:265674
First Author: Jansson L
Year: 2018
Journal: Endocrinology
Title: Immunotherapy With Apitopes Blocks the Immune Response to TSH Receptor in HLA-DR Transgenic Mice.
Volume: 159
Issue: 9
Pages: 3446-3457
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Publication
19204074 | J:150549
First Author: Ingram RJ
Year: 2009
Journal: FASEB J
Title: A role of cellular prion protein in programming T-cell cytokine responses in disease.
Volume: 23
Issue: 6
Pages: 1672-84
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Publication
32601313 | J:296369
First Author: Henjum K
Year: 2020
Journal: Sci Rep
Title: Analyzing microglial-associated Aβ in Alzheimer's disease transgenic mice with a novel mid-domain Aβ-antibody.
Volume: 10
Issue: 1
Pages: 10590
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Publication
29577934 | J:264748
First Author: van Hummel A
Year: 2018
Journal: Am J Pathol
Title: Selective Spatiotemporal Vulnerability of Central Nervous System Neurons to Pathologic TAR DNA-Binding Protein 43 in Aged Transgenic Mice.
Volume: 188
Issue: 6
Pages: 1447-1456
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Publication
26892305 | J:234738
 
First Author: Sehlin D
Year: 2016
Journal: Nat Commun
Title: Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer's disease.
Volume: 7
Pages: 10759
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Publication
32371051 | J:294557
First Author: Chan G
Year: 2020
Journal: Am J Pathol
Title: Neurodegeneration and Motor Deficits in the Absence of Astrogliosis upon Transgenic Mutant TDP-43 Expression in Mature Mice.
Volume: 190
Issue: 8
Pages: 1713-1722
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Publication
29222502 | J:288081
First Author: Sehlin D
Year: 2017
Journal: Sci Rep
Title: Pharmacokinetics, biodistribution and brain retention of a bispecific antibody-based PET radioligand for imaging of amyloid-β.
Volume: 7
Issue: 1
Pages: 17254
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Gene
51520 | LARS1
Type: gene
Organism: human
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Allele
Tg(Cd3d-CD4,H2-Ea-HLA-DRA*0101,-HLA-DRB1*0401)#Lfug | MGI:6202583
Name: transgene insertion, Lars Fugger
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(TCROb.1A12)#Lfug | MGI:5429700
Name: transgene insertion, Lars Fugger
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(tetO-TARDBP*A315T)6Lmit | MGI:5922009
Name: transgene insertion, Lars M Ittner
Allele Type: Transgenic
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Allele
Tg(HLA-DR2)#Lfug | MGI:5429698
Name: transgene insertion, Lars Fugger
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Thy1-APPSwe)1Lngn | MGI:4420244
Name: transgene insertion 1, Lars Nilsson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(tetO-TARDBP*A315T)#Lmit | MGI:5920009
Name: transgene insertion, Lars M Ittner
Allele Type: Transgenic
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Allele
Tg(Thy1-APPSweArc)BLngn | MGI:4420229
Name: transgene insertion B, Lars Nilsson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
20374285 | J:159617
First Author: Israelsson C
Year: 2010
Journal: Eur J Neurosci
Title: Appearance of Cxcl10-expressing cell clusters is common for traumatic brain injury and neurodegenerative disorders.
Volume: 31
Issue: 5
Pages: 852-63
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Publication
19215301 | J:147883
First Author: Lord A
Year: 2009
Journal: FEBS J
Title: Amyloid-beta protofibril levels correlate with spatial learning in Arctic Alzheimer's disease transgenic mice.
Volume: 276
Issue: 4
Pages: 995-1006
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Publication
10610182 | J:134764
First Author: Madsen LS
Year: 1999
Journal: Nat Genet
Title: A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor.
Volume: 23
Issue: 3
Pages: 343-7
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Publication
28334913 | J:242322
First Author: Moujalled D
Year: 2017
Journal: Hum Mol Genet
Title: TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway.
Volume: 26
Issue: 9
Pages: 1732-1746
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Allele
Tg(tetO-TARDBP*A315T)13Lmit | MGI:5922010
Name: transgene insertion 13, Lars M Ittner
Allele Type: Transgenic
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Allele
Cd22<tm3Lnit> | MGI:5526058
 
Name: CD22 antigen; targeted mutation 3, Lars Nitschke
Allele Type: Targeted
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Allele
Cd22<tm1.1(CD22)Lnit> | MGI:5446371
 
Name: CD22 antigen; targeted mutation 1.1, Lars Nitschke
Allele Type: Targeted
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Allele
Cd22<tm1Lnit> | MGI:5526055
Name: CD22 antigen; targeted mutation 1, Lars Nitschke
Allele Type: Targeted
Attribute String: Not Specified
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Allele
Cd22<tm2Lnit> | MGI:5526056
 
Name: CD22 antigen; targeted mutation 2, Lars Nitschke
Allele Type: Targeted
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Allele
Amotl2<tm1.1Laho> | MGI:6120889
Name: angiomotin-like 2; targeted mutation 1.1, Lars Holmgren
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Tg(Thy1-tTA)15Lmit | MGI:5922014
Name: transgene insertion 15, Lars M Ittner
Allele Type: Transgenic
Attribute String: Transactivator
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Allele
Tg(Thy1-tTA)6Lmit | MGI:5922013
Name: transgene insertion 6, Lars M Ittner
Allele Type: Transgenic
Attribute String: Transactivator
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Allele
Trhde<tm1Lars> | MGI:3767397
Name: TRH-degrading enzyme; targeted mutation 1, Lars Geffers
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cd83<tm1.1Lnjt> | MGI:5819103
Name: CD83 antigen; targeted mutation 1.1, Lars Nitschke
Allele Type: Targeted
Attribute String: Conditional ready
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Strain
MGI:4419014 | B6.Cg-Tg(Thy1-APPSweArc)BLngn/J
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:5708586 | B6J.Cg-Tg(Thy1-APPSweArc)BLngn
Attribute String: transgenic, mutant strain, congenic
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Allele
Amotl1<tm1Laho> | MGI:6356823
Name: angiomotin-like 1; targeted mutation 1, Lars Holmgren
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Dnase1<em1Lnit> | MGI:7581011
Name: deoxyribonuclease I; endonuclease-mediated mutation 1, Lars Nitschke
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Tg(Thy1-APPSwe)1Lngn/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-APPSweArc)BLngn/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-APPSweArc)BLngn/?
Background: B6J.Cg-Tg(Thy1-APPSweArc)BLngn
Zygosity: ot
Has Mutant Allele: true
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Publication
22888134 | J:189816
First Author: Quandt JA
Year: 2012
Journal: J Immunol
Title: Myelin basic protein-specific TCR/HLA-DRB5*01:01 transgenic mice support the etiologic role of DRB5*01:01 in multiple sclerosis.
Volume: 189
Issue: 6
Pages: 2897-908
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Publication
24214494 | J:213543
First Author: Delerue F
Year: 2014
Journal: Transgenic Res
Title: Inducible, tightly regulated and non-leaky neuronal gene expression in mice.
Volume: 23
Issue: 2
Pages: 225-33
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Publication
26437864 | J:245760
First Author: Ke YD
Year: 2015
Journal: Acta Neuropathol
Title: Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.
Volume: 130
Issue: 5
Pages: 661-78
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DO Term
DOID:0080717 | infantile liver failure syndrome 1
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Allele
Mapt<tm1.1Lngn> | MGI:5698834
Name: microtubule-associated protein tau; targeted mutation 1.1, Lars NG Nilsson
Allele Type: Targeted
Attribute String: Modified isoform(s)
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Allele
Nrg1<tm1Leth> | MGI:1928491
Name: neuregulin 1; targeted mutation 1, Lars E Theill
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
22965838 | J:189017
First Author: Wöhner M
Year: 2012
Journal: Eur J Immunol
Title: Human CD22 cannot fully substitute murine CD22 functions in vivo, as shown in a new knockin mouse model.
Volume: 42
Issue: 11
Pages: 3009-18
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Publication
27352780 | J:252029
First Author: Özgör L
Year: 2016
Journal: Eur J Immunol
Title: Epratuzumab modulates B-cell signaling without affecting B-cell numbers or B-cell functions in a mouse model with humanized CD22.
Volume: 46
Issue: 9
Pages: 2260-72
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Publication
32592176 | J:308847
First Author: Brandl C
Year: 2020
Journal: Eur J Immunol
Title: Humanized CD22 transgenic mouse model for in vivo analysis of anti-CD22-based immunotherapy.
Volume: 50
Issue: 11
Pages: 1834-1837
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Allele
Igh<tm1.1Lnit> | MGI:3702524
Name: immunoglobulin heavy chain complex; targeted mutation 1.1, Lars Nitschke
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
16123981 | J:101025
First Author: Yaylaoglu MB
Year: 2005
Journal: Dev Dyn
Title: Comprehensive expression atlas of fibroblast growth factors and their receptors generated by a novel robotic in situ hybridization platform.
Volume: 234
Issue: 2
Pages: 371-86
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Publication
- | J:128543
 
First Author: Geffers L
Year: 2004
Journal: FENS Forum Abstracts
Title: Generation of thyrotropin-releasing hormone-degrading ectoenzyme (TRH-DE) deficient mice by targeted recombination
Volume: 2
Pages: A046.5 (abstr)
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Publication
- | J:128544
     
First Author: Geffers L
Year: 2005
Journal: MGI Direct Data Submission
Title: (Production and analysis of a mouse with knock-out of the TRH-DE gene) Approved PhD dissertation: (Faculty of Natural Sciences, University of Hannover)
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Genotype
Genotype
Symbol: Cd22/Cd22
Background: involves: 129S4/SvJae
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd22/Cd22
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd22/Cd22
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd22/Cd22
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd83/Cd83
Background: involves: C57BL/6 * C57BL/6N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Trhde/Trhde
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Allele
Siglecg<tm2.1Lnit> | MGI:6202624
Name: sialic acid binding Ig-like lectin G; targeted mutation 2.1, Lars Nitschke
Allele Type: Targeted
Attribute String: Not Specified
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Allele
Siglecg<tm1Lnit> | MGI:3718495
Name: sialic acid binding Ig-like lectin G; targeted mutation 1, Lars Nitschke
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
24261309 | J:221311
 
First Author: Gumucio A
Year: 2013
Journal: BMC Neurosci
Title: Lack of exon 10 in the murine tau gene results in mild sensorimotor defects with aging.
Volume: 14
Pages: 148
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Publication
8643489 | J:33038
First Author: Kramer R
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development.
Volume: 93
Issue: 10
Pages: 4833-8
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Publication
16835362 | J:124721
First Author: Mann MA
Year: 2006
Journal: J Neurophysiol
Title: Neuregulin effect on quantal content dissociated from effect on miniature endplate potential amplitude.
Volume: 96
Issue: 2
Pages: 671-6
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Publication
15706234 | J:103529
First Author: Rimer M
Year: 2005
Journal: Neuroreport
Title: Neuregulin-1 immunoglobulin-like domain mutant mice: clozapine sensitivity and impaired latent inhibition.
Volume: 16
Issue: 3
Pages: 271-5
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Publication
9110980 | J:39800
First Author: Sandrock AW Jr
Year: 1997
Journal: Science
Title: Maintenance of acetylcholine receptor number by neuregulins at the neuromuscular junction in vivo.
Volume: 276
Issue: 5312
Pages: 599-603
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Allele
Lamp5<em1Lmit> | MGI:7608054
Name: lysosomal-associated membrane protein family, member 5; endonuclease-mediated mutation 1, Lars M Ittner
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
H2-DMa<tm1Lkrl> | MGI:2652160
Name: histocompatibility 2, class II, locus DMa; targeted mutation 1, Lars Karlsson
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Fam181b<tm1.2Lswr> | MGI:5780054
Name: family with sequence similarity 181, member B; targeted mutation 1.2, Lars Wittler
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Fam181b<tm1.1Lswr> | MGI:5780053
Name: family with sequence similarity 181, member B; targeted mutation 1.1, Lars Wittler
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Grb2<tm1Lnit> | MGI:4949889
Name: growth factor receptor bound protein 2; targeted mutation 1, Lars Nitschke
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Grb2<tm1.1Lnit> | MGI:5568397
Name: growth factor receptor bound protein 2; targeted mutation 1.1, Lars Nitschke
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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