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Search results 1 to 100 out of 197 for Lars

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Hits by Pathway

Hits by Category

Type Details Score
Gene
416347 | LARS
Type: gene
Organism: chicken
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Transgene
MGI:6202615 | Tg(Cd3d-CD4,H2-Ea-HLA-DRA*0101,-HLA-DRB1*0401)#Lfug
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5429697 | Tg(HLA-DR2)#Lfug
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5429699 | Tg(TCROb.1A12)#Lfug
Type: transgene
Organism: mouse, laboratory
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Protein
Q99JK2
Organism: Mus musculus/domesticus
Length: 438  
Fragment?: false
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Publication
20059576 | J:166417
First Author: Buenafe AC
Year: 2010
Journal: Immunology
Title: Prevention and treatment of experimental autoimmune encephalomyelitis with clonotypic CDR3 peptides: CD4(+) Foxp3(+) T-regulatory cells suppress interleukin-2-dependent expansion of myelin basic protein-specific T cells.
Volume: 130
Issue: 1
Pages: 114-24
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Publication
24683185 | J:209975
First Author: Meza-Romero R
Year: 2014
Journal: J Immunol
Title: HLA-DRα1 constructs block CD74 expression and MIF effects in experimental autoimmune encephalomyelitis.
Volume: 192
Issue: 9
Pages: 4164-73
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Publication
8016129 | J:265804
First Author: Fugger L
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Expression of HLA-DR4 and human CD4 transgenes in mice determines the variable region beta-chain T-cell repertoire and mediates an HLA-DR-restricted immune response.
Volume: 91
Issue: 13
Pages: 6151-5
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Transgene
MGI:4420242 | Tg(Thy1-APPSwe)1Lngn
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5922005 | Tg(tetO-TARDBP*A315T)#Lmit
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5922011 | Tg(tetO-TARDBP*A315T)6Lmit
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5922012 | Tg(tetO-TARDBP*A315T)13Lmit
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5922017 | Tg(Thy1-tTA)6Lmit
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5922018 | Tg(Thy1-tTA)15Lmit
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:4420230 | Tg(Thy1-APPSweArc)BLngn
Type: transgene
Organism: mouse, laboratory
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Publication
25089901 | J:223167
First Author: Nuruddin S
Year: 2014
Journal: PLoS One
Title: Elevated mRNA-levels of gonadotropin-releasing hormone and its receptor in plaque-bearing Alzheimer's disease transgenic mice.
Volume: 9
Issue: 8
Pages: e103607
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Publication
24126157 | J:212602
First Author: Lillehaug S
Year: 2014
Journal: Neurobiol Aging
Title: Brainwide distribution and variance of amyloid-beta deposits in tg-ArcSwe mice.
Volume: 35
Issue: 3
Pages: 556-64
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Publication
20615433 | J:162999
First Author: Codita A
Year: 2010
Journal: Behav Brain Res
Title: Impaired behavior of female tg-ArcSwe APP mice in the IntelliCage: A longitudinal study.
Volume: 215
Issue: 1
Pages: 83-94
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Publication
35833623 | J:327137
   
First Author: Åbjørsbråten KS
Year: 2022
Journal: Elife
Title: Impaired astrocytic Ca2+ signaling in awake-behaving Alzheimer's disease transgenic mice.
Volume: 11
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Publication
30814252 | J:278232
First Author: Michno W
Year: 2019
Journal: J Biol Chem
Title: Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1-40 deposition underlies plaque polymorphism in progressing Alzheimer's disease pathology.
Volume: 294
Issue: 17
Pages: 6719-6732
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Publication
31605538 | J:285316
First Author: Michno W
Year: 2020
Journal: J Neurochem
Title: Chemical imaging of evolving amyloid plaque pathology and associated Aβ peptide aggregation in a transgenic mouse model of Alzheimer's disease.
Volume: 152
Issue: 5
Pages: 602-616
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Publication
27034428 | J:234697
First Author: Lai JD
Year: 2016
Journal: Blood
Title: Concurrent influenza vaccination reduces anti-FVIII antibody responses in murine hemophilia A.
Volume: 127
Issue: 26
Pages: 3439-49
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Publication
23549081 | J:197610
First Author: Roth AJ
Year: 2013
Journal: J Clin Invest
Title: Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis.
Volume: 123
Issue: 4
Pages: 1773-83
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Publication
22955884 | J:190144
First Author: Ooi JD
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis.
Volume: 109
Issue: 39
Pages: E2615-24
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Publication
16298242 | J:105265
First Author: Lord A
Year: 2006
Journal: Neurobiol Aging
Title: The Arctic Alzheimer mutation facilitates early intraneuronal Abeta aggregation and senile plaque formation in transgenic mice.
Volume: 27
Issue: 1
Pages: 67-77
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Publication
21514441 | J:171581
First Author: Lord A
Year: 2011
Journal: Am J Pathol
Title: Observations in APP bitransgenic mice suggest that diffuse and compact plaques form via independent processes in Alzheimer's disease.
Volume: 178
Issue: 5
Pages: 2286-98
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Publication
18192084 | J:152959
First Author: Philipson O
Year: 2009
Journal: Neurobiol Aging
Title: A highly insoluble state of Abeta similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice.
Volume: 30
Issue: 9
Pages: 1393-405
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Publication
30872722 | J:276682
First Author: Jendresen C
Year: 2019
Journal: Sci Rep
Title: Systemic LPS-induced Aβ-solubilization and clearance in AβPP-transgenic mice is diminished by heparanase overexpression.
Volume: 9
Issue: 1
Pages: 4600
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Publication
25548284 | J:276782
First Author: Jendresen CB
Year: 2015
Journal: J Biol Chem
Title: Overexpression of heparanase lowers the amyloid burden in amyloid-β precursor protein transgenic mice.
Volume: 290
Issue: 8
Pages: 5053-64
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Publication
22576344 | J:223137
First Author: Klyushnenkova EN
Year: 2012
Journal: J Immunother
Title: A cytomegalovirus-based vaccine expressing a single tumor-specific CD8+ T-cell epitope delays tumor growth in a murine model of prostate cancer.
Volume: 35
Issue: 5
Pages: 390-9
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Protein
Q8BMJ2
Organism: Mus musculus/domesticus
Length: 1178  
Fragment?: false
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Publication
24227784 | J:207124
First Author: Sosa RA
Year: 2013
Journal: J Immunol
Title: The kinetics of myelin antigen uptake by myeloid cells in the central nervous system during experimental autoimmune encephalomyelitis.
Volume: 191
Issue: 12
Pages: 5848-57
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Publication
30099489 | J:265674
First Author: Jansson L
Year: 2018
Journal: Endocrinology
Title: Immunotherapy With Apitopes Blocks the Immune Response to TSH Receptor in HLA-DR Transgenic Mice.
Volume: 159
Issue: 9
Pages: 3446-3457
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Publication
19204074 | J:150549
First Author: Ingram RJ
Year: 2009
Journal: FASEB J
Title: A role of cellular prion protein in programming T-cell cytokine responses in disease.
Volume: 23
Issue: 6
Pages: 1672-84
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Publication
32601313 | J:296369
First Author: Henjum K
Year: 2020
Journal: Sci Rep
Title: Analyzing microglial-associated Aβ in Alzheimer's disease transgenic mice with a novel mid-domain Aβ-antibody.
Volume: 10
Issue: 1
Pages: 10590
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Gene
51520 | LARS1
Type: gene
Organism: human
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Publication
29222502 | J:288081
First Author: Sehlin D
Year: 2017
Journal: Sci Rep
Title: Pharmacokinetics, biodistribution and brain retention of a bispecific antibody-based PET radioligand for imaging of amyloid-β.
Volume: 7
Issue: 1
Pages: 17254
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Publication
26892305 | J:234738
 
First Author: Sehlin D
Year: 2016
Journal: Nat Commun
Title: Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer's disease.
Volume: 7
Pages: 10759
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Publication
32371051 | J:294557
First Author: Chan G
Year: 2020
Journal: Am J Pathol
Title: Neurodegeneration and Motor Deficits in the Absence of Astrogliosis upon Transgenic Mutant TDP-43 Expression in Mature Mice.
Volume: 190
Issue: 8
Pages: 1713-1722
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Publication
29577934 | J:264748
First Author: van Hummel A
Year: 2018
Journal: Am J Pathol
Title: Selective Spatiotemporal Vulnerability of Central Nervous System Neurons to Pathologic TAR DNA-Binding Protein 43 in Aged Transgenic Mice.
Volume: 188
Issue: 6
Pages: 1447-1456
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Allele
Tg(Thy1-APPSweArc)BLngn | MGI:4420229
Name: transgene insertion B, Lars Nilsson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Thy1-APPSwe)1Lngn | MGI:4420244
Name: transgene insertion 1, Lars Nilsson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(HLA-DR2)#Lfug | MGI:5429698
Name: transgene insertion, Lars Fugger
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(TCROb.1A12)#Lfug | MGI:5429700
Name: transgene insertion, Lars Fugger
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(tetO-TARDBP*A315T)#Lmit | MGI:5920009
Name: transgene insertion, Lars M Ittner
Allele Type: Transgenic
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Allele
Tg(tetO-TARDBP*A315T)6Lmit | MGI:5922009
Name: transgene insertion, Lars M Ittner
Allele Type: Transgenic
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Allele
Tg(Cd3d-CD4,H2-Ea-HLA-DRA*0101,-HLA-DRB1*0401)#Lfug | MGI:6202583
Name: transgene insertion, Lars Fugger
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
19215301 | J:147883
First Author: Lord A
Year: 2009
Journal: FEBS J
Title: Amyloid-beta protofibril levels correlate with spatial learning in Arctic Alzheimer's disease transgenic mice.
Volume: 276
Issue: 4
Pages: 995-1006
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Publication
20374285 | J:159617
First Author: Israelsson C
Year: 2010
Journal: Eur J Neurosci
Title: Appearance of Cxcl10-expressing cell clusters is common for traumatic brain injury and neurodegenerative disorders.
Volume: 31
Issue: 5
Pages: 852-63
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Publication
10610182 | J:134764
First Author: Madsen LS
Year: 1999
Journal: Nat Genet
Title: A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor.
Volume: 23
Issue: 3
Pages: 343-7
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Publication
28334913 | J:242322
First Author: Moujalled D
Year: 2017
Journal: Hum Mol Genet
Title: TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway.
Volume: 26
Issue: 9
Pages: 1732-1746
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Allele
Trhde<tm1Lars> | MGI:3767397
Name: TRH-degrading enzyme; targeted mutation 1, Lars Geffers
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Strain
MGI:5708586 | B6J.Cg-Tg(Thy1-APPSweArc)BLngn
Attribute String: transgenic, mutant strain, congenic
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Strain
MGI:4419014 | B6.Cg-Tg(Thy1-APPSweArc)BLngn/J
Attribute String: congenic, mutant strain, transgenic
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Allele
Cd22<tm1.1(CD22)Lnit> | MGI:5446371
 
Name: CD22 antigen; targeted mutation 1.1, Lars Nitschke
Allele Type: Targeted
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Allele
Cd22<tm1Lnit> | MGI:5526055
Name: CD22 antigen; targeted mutation 1, Lars Nitschke
Allele Type: Targeted
Attribute String: Not Specified
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Allele
Cd22<tm2Lnit> | MGI:5526056
 
Name: CD22 antigen; targeted mutation 2, Lars Nitschke
Allele Type: Targeted
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Allele
Cd22<tm3Lnit> | MGI:5526058
 
Name: CD22 antigen; targeted mutation 3, Lars Nitschke
Allele Type: Targeted
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Allele
Cd83<tm1.1Lnjt> | MGI:5819103
Name: CD83 antigen; targeted mutation 1.1, Lars Nitschke
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Amotl2<tm1.1Laho> | MGI:6120889
Name: angiomotin-like 2; targeted mutation 1.1, Lars Holmgren
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Tg(tetO-TARDBP*A315T)13Lmit | MGI:5922010
Name: transgene insertion 13, Lars M Ittner
Allele Type: Transgenic
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Allele
Tg(Thy1-tTA)6Lmit | MGI:5922013
Name: transgene insertion 6, Lars M Ittner
Allele Type: Transgenic
Attribute String: Transactivator
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Allele
Tg(Thy1-tTA)15Lmit | MGI:5922014
Name: transgene insertion 15, Lars M Ittner
Allele Type: Transgenic
Attribute String: Transactivator
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Allele
Amotl1<tm1Laho> | MGI:6356823
Name: angiomotin-like 1; targeted mutation 1, Lars Holmgren
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Dnase1<em1Lnit> | MGI:7581011
Name: deoxyribonuclease I; endonuclease-mediated mutation 1, Lars Nitschke
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Tbx6<em1Lswr> | MGI:7662519
Name: T-box 6; endonuclease-mediated mutation 1, Lars Wittler
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Tg(Thy1-APPSwe)1Lngn/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-APPSweArc)BLngn/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-APPSweArc)BLngn/?
Background: B6J.Cg-Tg(Thy1-APPSweArc)BLngn
Zygosity: ot
Has Mutant Allele: true
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Publication
22888134 | J:189816
First Author: Quandt JA
Year: 2012
Journal: J Immunol
Title: Myelin basic protein-specific TCR/HLA-DRB5*01:01 transgenic mice support the etiologic role of DRB5*01:01 in multiple sclerosis.
Volume: 189
Issue: 6
Pages: 2897-908
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Publication
24214494 | J:213543
First Author: Delerue F
Year: 2014
Journal: Transgenic Res
Title: Inducible, tightly regulated and non-leaky neuronal gene expression in mice.
Volume: 23
Issue: 2
Pages: 225-33
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Publication
38366598 | J:348663
First Author: Ke YD
Year: 2024
Journal: Neuron
Title: Targeting 14-3-3θ-mediated TDP-43 pathology in amyotrophic lateral sclerosis and frontotemporal dementia mice.
Volume: 112
Issue: 8
Pages: 1249-1264.e8
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Publication
26437864 | J:245760
First Author: Ke YD
Year: 2015
Journal: Acta Neuropathol
Title: Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.
Volume: 130
Issue: 5
Pages: 661-78
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DO Term
DOID:0080717 | infantile liver failure syndrome 1
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Allele
Nrg1<tm1Leth> | MGI:1928491
Name: neuregulin 1; targeted mutation 1, Lars E Theill
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Igh<tm1.1Lnit> | MGI:3702524
Name: immunoglobulin heavy chain complex; targeted mutation 1.1, Lars Nitschke
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
16123981 | J:101025
First Author: Yaylaoglu MB
Year: 2005
Journal: Dev Dyn
Title: Comprehensive expression atlas of fibroblast growth factors and their receptors generated by a novel robotic in situ hybridization platform.
Volume: 234
Issue: 2
Pages: 371-86
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Publication
- | J:128543
 
First Author: Geffers L
Year: 2004
Journal: FENS Forum Abstracts
Title: Generation of thyrotropin-releasing hormone-degrading ectoenzyme (TRH-DE) deficient mice by targeted recombination
Volume: 2
Pages: A046.5 (abstr)
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Publication
- | J:128544
     
First Author: Geffers L
Year: 2005
Journal: MGI Direct Data Submission
Title: (Production and analysis of a mouse with knock-out of the TRH-DE gene) Approved PhD dissertation: (Faculty of Natural Sciences, University of Hannover)
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Publication
22965838 | J:189017
First Author: Wöhner M
Year: 2012
Journal: Eur J Immunol
Title: Human CD22 cannot fully substitute murine CD22 functions in vivo, as shown in a new knockin mouse model.
Volume: 42
Issue: 11
Pages: 3009-18
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Publication
32592176 | J:308847
First Author: Brandl C
Year: 2020
Journal: Eur J Immunol
Title: Humanized CD22 transgenic mouse model for in vivo analysis of anti-CD22-based immunotherapy.
Volume: 50
Issue: 11
Pages: 1834-1837
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Publication
27352780 | J:252029
First Author: Özgör L
Year: 2016
Journal: Eur J Immunol
Title: Epratuzumab modulates B-cell signaling without affecting B-cell numbers or B-cell functions in a mouse model with humanized CD22.
Volume: 46
Issue: 9
Pages: 2260-72
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Allele
Mapt<tm1.1Lngn> | MGI:5698834
Name: microtubule-associated protein tau; targeted mutation 1.1, Lars NG Nilsson
Allele Type: Targeted
Attribute String: Modified isoform(s)
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Publication
31527313 | J:296997
 
First Author: Wild AB
Year: 2019
Journal: JCI Insight
Title: CD83 orchestrates immunity toward self and non-self in dendritic cells.
Volume: 4
Issue: 20
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Allele
Tardbp<em1Lmit> | MGI:7645439
 
Name: TAR DNA binding protein; endonuclease-mediated mutation 1, Lars M Ittner
Allele Type: Endonuclease-mediated
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Publication
37414952 | J:342640
First Author: Sampath Kumar A
Year: 2023
Journal: Nat Genet
Title: Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis.
Volume: 55
Issue: 7
Pages: 1176-1185
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Genotype
Genotype
Symbol: Cd22/Cd22
Background: involves: 129S4/SvJae
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd22/Cd22
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd22/Cd22
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd22/Cd22
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd83/Cd83
Background: involves: C57BL/6 * C57BL/6N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Trhde/Trhde
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Publication
37973869 | J:348885
First Author: Zielinski M
Year: 2023
Journal: Nat Neurosci
Title: Cryo-EM of Aβ fibrils from mouse models find tg-APP(ArcSwe) fibrils resemble those found in patients with sporadic Alzheimer's disease.
Volume: 26
Issue: 12
Pages: 2073-2080
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Publication
8643489 | J:33038
First Author: Kramer R
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development.
Volume: 93
Issue: 10
Pages: 4833-8
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Publication
9110980 | J:39800
First Author: Sandrock AW Jr
Year: 1997
Journal: Science
Title: Maintenance of acetylcholine receptor number by neuregulins at the neuromuscular junction in vivo.
Volume: 276
Issue: 5312
Pages: 599-603
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Publication
15706234 | J:103529
First Author: Rimer M
Year: 2005
Journal: Neuroreport
Title: Neuregulin-1 immunoglobulin-like domain mutant mice: clozapine sensitivity and impaired latent inhibition.
Volume: 16
Issue: 3
Pages: 271-5
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Publication
16835362 | J:124721
First Author: Mann MA
Year: 2006
Journal: J Neurophysiol
Title: Neuregulin effect on quantal content dissociated from effect on miniature endplate potential amplitude.
Volume: 96
Issue: 2
Pages: 671-6
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Allele
H2-DMa<tm1Lkrl> | MGI:2652160
Name: histocompatibility 2, class II, locus DMa; targeted mutation 1, Lars Karlsson
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
H2-Oa<tm1Lkar> | MGI:2675254
Name: histocompatibility 2, O region alpha locus; targeted mutation 1, Lars Karlsson
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Siglecg<tm1Lnit> | MGI:3718495
Name: sialic acid binding Ig-like lectin G; targeted mutation 1, Lars Nitschke
Allele Type: Targeted
Attribute String: Null/knockout
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