|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 231 for Lats1

<< First    < Previous  |  Next >    Last >>
0.103s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
9113 | LATS1
Type: gene
Organism: human
•
•
•
•
•
Gene
308265 | Lats1
Type: gene
Organism: rat
•
•
•
•
•
Gene
535935 | LATS1
Type: gene
Organism: cattle
•
•
•
•
•
Gene
421627 | LATS1
Type: gene
Organism: chicken
•
•
•
•
•
Gene
553164 | lats1
Type: gene
Organism: zebrafish
•
•
•
•
•
Gene
696131 | LATS1
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
100145677 | lats1
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Protein Domain
IPR028741 | LATS1
Type: Family
Description: There are two mammalian homologue of Drosophila tumor suppressor Lats (large tumor suppressor, also known as Warts): LATS1 and LATS2. Lats/Warts is a serine/threonine-protein kinase that negatively regulates YAP1 (Drosophila Yorkie (Yki) homologue) in the Hippo signaling pathway, which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis [, ]. This entry represents LATS1 from mammals. During cell division, LATS1 interacts with MOB1A and serves as a mitotic exit network kinase [].
•
•
•
•
•
Gene
476241 | LATS1
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
748397 | LATS1
Type: gene
Organism: chimpanzee
•
•
•
•
•
Protein Coding Gene
MGI:1333883 | Lats1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7408355
Assay Type: RNA in situ
Annotation Date: 2022-12-16
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689417
Pattern: Punctate
Stage: TS17
Assay Id: MGI:7408371
Age: embryonic day 10.5
Image: S1A Lats1
Note: Expression in cranial neuroepithelium, more enriched than for Lats2.
Specimen Label: S1A Lats1
Detected: true
Specimen Num: 1
•
•
•
•
•
Publication
18158288 | -
First Author: Hao Y
Year: 2008
Journal: J Biol Chem
Title: Tumor suppressor LATS1 is a negative regulator of oncogene YAP.
Volume: 283
Issue: 9
Pages: 5496-509
•
•
•
•
•
Publication
16061636 | -
First Author: Bothos J
Year: 2005
Journal: Cancer Res
Title: Human LATS1 is a mitotic exit network kinase.
Volume: 65
Issue: 15
Pages: 6568-75
•
•
•
•
•
Protein
Q8BYR2
Organism: Mus musculus/domesticus
Length: 1129  
Fragment?: false
•
•
•
•
•
Publication
9988269 | J:52536
First Author: St John MA
Year: 1999
Journal: Nat Genet
Title: Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction.
Volume: 21
Issue: 2
Pages: 182-6
•
•
•
•
•
Publication
16096061 | -
First Author: Huang J
Year: 2005
Journal: Cell
Title: The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP.
Volume: 122
Issue: 3
Pages: 421-34
•
•
•
•
•
Publication
31848340 | J:283786
First Author: Tang F
Year: 2019
Journal: Nat Commun
Title: LATS1 but not LATS2 represses autophagy by a kinase-independent scaffold function.
Volume: 10
Issue: 1
Pages: 5755
•
•
•
•
•
Publication
26040669 | J:224465
First Author: Sun T
Year: 2015
Journal: Biol Reprod
Title: Lats1 Deletion Causes Increased Germ Cell Apoptosis and Follicular Cysts in Mouse Ovaries.
Volume: 93
Issue: 1
Pages: 22
•
•
•
•
•
Publication
23230145 | J:200232
First Author: Yabuta N
Year: 2013
Journal: J Cell Sci
Title: N-terminal truncation of Lats1 causes abnormal cell growth control and chromosomal instability.
Volume: 126
Issue: Pt 2
Pages: 508-20
•
•
•
•
•
Publication
33515576 | J:306379
 
First Author: Mohad V
Year: 2021
Journal: Dev Biol
Title: Inactivation of Lats1 and Lats2 highlights the role of hippo pathway effector YAP in larynx and vocal fold epithelium morphogenesis.
Volume: 473
Pages: 33-49
•
•
•
•
•
Publication
34984591 | J:332781
First Author: Nezhad FY
Year: 2022
Journal: Transgenic Res
Title: Skeletal muscle phenotyping of Hippo gene-mutated mice reveals that Lats1 deletion increases the percentage of type I muscle fibers.
Volume: 31
Issue: 2
Pages: 227-237
•
•
•
•
•
Publication
36362374 | J:331266
 
First Author: Abou Nader N
Year: 2022
Journal: Int J Mol Sci
Title: Targeted Disruption of Lats1 and Lats2 in Mice Impairs Testis Development and Alters Somatic Cell Fate.
Volume: 23
Issue: 21
•
•
•
•
•
Publication
32243503 | J:289490
 
First Author: Ménard A
Year: 2020
Journal: Endocrinology
Title: Targeted Disruption of Lats1 and Lats2 in Mice Impairs Adrenal Cortex Development and Alters Adrenocortical Cell Fate.
Volume: 161
Issue: 5
•
•
•
•
•
Publication
31268774 | J:289886
First Author: Tsoi M
Year: 2019
Journal: FASEB J
Title: Lats1 and Lats2 are required for ovarian granulosa cell fate maintenance.
Volume: 33
Issue: 10
Pages: 10819-10832
•
•
•
•
•
Publication
31575647 | J:284144
 
First Author: St-Jean G
Year: 2019
Journal: Development
Title: Lats1 and Lats2 are required for the maintenance of multipotency in the Müllerian duct mesenchyme.
Volume: 146
Issue: 20
•
•
•
•
•
Publication
21145499 | J:169049
First Author: Varelas X
Year: 2010
Journal: Dev Cell
Title: The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.
Volume: 19
Issue: 6
Pages: 831-44
•
•
•
•
•
Publication
22641346 | J:185202
First Author: Chiyoda T
Year: 2012
Journal: J Cell Biol
Title: LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and regulate mammalian mitotic progression.
Volume: 197
Issue: 5
Pages: 625-41
•
•
•
•
•
Publication
15343267 | J:93191
First Author: McPherson JP
Year: 2004
Journal: EMBO J
Title: Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity.
Volume: 23
Issue: 18
Pages: 3677-88
•
•
•
•
•
Publication
32015438 | J:291607
First Author: Gan W
Year: 2020
Journal: Nat Cell Biol
Title: LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control.
Volume: 22
Issue: 2
Pages: 246-256
•
•
•
•
•
Publication
31067451 | J:278722
First Author: Rueda EM
Year: 2019
Journal: Cell Rep
Title: The Hippo Pathway Blocks Mammalian Retinal Müller Glial Cell Reprogramming.
Volume: 27
Issue: 6
Pages: 1637-1649.e6
•
•
•
•
•
Publication
25218637 | J:217712
First Author: Pefani DE
Year: 2014
Journal: Nat Cell Biol
Title: RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2.
Volume: 16
Issue: 10
Pages: 962-71, 1-8
•
•
•
•
•
Publication
32404936 | J:288977
First Author: Eder N
Year: 2020
Journal: Nat Commun
Title: YAP1/TAZ drives ependymoma-like tumour formation in mice.
Volume: 11
Issue: 1
Pages: 2380
•
•
•
•
•
Publication
36443313 | J:331705
First Author: Kern JG
Year: 2022
Journal: Nat Commun
Title: Inactivation of LATS1/2 drives luminal-basal plasticity to initiate basal-like mammary carcinomas.
Volume: 13
Issue: 1
Pages: 7198
•
•
•
•
•
Publication
29689192 | J:263874
First Author: Xiao Y
Year: 2018
Journal: Dev Cell
Title: Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development.
Volume: 45
Issue: 2
Pages: 153-169.e6
•
•
•
•
•
Publication
28492365 | J:256856
   
First Author: Szymaniak AD
Year: 2017
Journal: Elife
Title: The Hippo pathway effector YAP is an essential regulator of ductal progenitor patterning in the mouse submandibular gland.
Volume: 6
•
•
•
•
•
Publication
32451369 | J:289356
First Author: Park J
Year: 2020
Journal: Mol Cells
Title: WWC1 and NF2 Prevent the Development of Intrahepatic Cholangiocarcinoma by Regulating YAP/TAZ Activity through LATS in Mice.
Volume: 43
Issue: 5
Pages: 491-499
•
•
•
•
•
Publication
27358050 | J:240786
 
First Author: Lee DH
Year: 2016
Journal: Nat Commun
Title: LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.
Volume: 7
Pages: 11961
•
•
•
•
•
Publication
31558567 | J:284169
First Author: Xiao Y
Year: 2019
Journal: Genes Dev
Title: Hippo pathway deletion in adult resting cardiac fibroblasts initiates a cell state transition with spontaneous and self-sustaining fibrosis.
Volume: 33
Issue: 21-22
Pages: 1491-1505
•
•
•
•
•
Publication
32900774 | J:299186
First Author: Park J
Year: 2020
Journal: Cancer Res
Title: YAP and AP-1 Cooperate to Initiate Pancreatic Cancer Development from Ductal Cells in Mice.
Volume: 80
Issue: 21
Pages: 4768-4779
•
•
•
•
•
Publication
33162027 | J:306138
 
First Author: Nishiyama T
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Deficiency of large tumor suppressor kinase 1 causes congenital hearing loss associated with cochlear abnormalities in mice.
Volume: 534
Pages: 921-926
•
•
•
•
•
Publication
36125128 | J:329537
 
First Author: Martínez Traverso IM
Year: 2022
Journal: Development
Title: LATS1/2 control TGFB-directed epithelial-to-mesenchymal transition in the murine dorsal cranial neuroepithelium through YAP regulation.
Volume: 149
Issue: 18
•
•
•
•
•
Publication
34267330 | J:309380
First Author: Mei L
Year: 2021
Journal: Oncogene
Title: SUMOylation activates large tumour suppressor 1 to maintain the tissue homeostasis during Hippo signalling.
Volume: 40
Issue: 35
Pages: 5357-5366
•
•
•
•
•
Publication
27647853 | J:307229
First Author: McNeill H
Year: 2017
Journal: J Am Soc Nephrol
Title: Lats1/2 Regulate Yap/Taz to Control Nephron Progenitor Epithelialization and Inhibit Myofibroblast Formation.
Volume: 28
Issue: 3
Pages: 852-861
•
•
•
•
•
Publication
30286078 | J:267193
First Author: Sun Z
Year: 2018
Journal: PLoS Genet
Title: FoxO6 regulates Hippo signaling and growth of the craniofacial complex.
Volume: 14
Issue: 10
Pages: e1007675
•
•
•
•
•
Publication
29849151 | J:263554
First Author: Du X
Year: 2018
Journal: Nature
Title: Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells.
Volume: 558
Issue: 7708
Pages: 141-145
•
•
•
•
•
Publication
30305289 | J:272609
 
First Author: Nantie LB
Year: 2018
Journal: Development
Title: Lats1/2 inactivation reveals Hippo function in alveolar type I cell differentiation during lung transition to air breathing.
Volume: 145
Issue: 21
•
•
•
•
•
Publication
27531557 | J:289492
First Author: Yi J
Year: 2016
Journal: Hepatology
Title: Large tumor suppressor homologs 1 and 2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ.
Volume: 64
Issue: 5
Pages: 1757-1772
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0015100 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0016997 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0016975 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0016939 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0016933 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0016758 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_1333883 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0017395 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0016340 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0016730 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0016838 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0016833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0016913 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0016863 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0017433 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0016125 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0016402 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0023719 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0015907 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Publication
10528150 | J:58428
First Author: Turenchalk GS
Year: 1999
Journal: Biochim Biophys Acta
Title: The role of lats in cell cycle regulation and tumorigenesis.
Volume: 1424
Issue: 2-3
Pages: M9-M16
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5763420
Assay Type: RT-PCR
Annotation Date: 2016-04-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:5763600
Age: embryonic day 0.5
Specimen Label: 1-cell
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5763420
Assay Type: RT-PCR
Annotation Date: 2016-04-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:5763600
Age: embryonic day 1.0
Specimen Label: 2-cell
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5763420
Assay Type: RT-PCR
Annotation Date: 2016-04-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:5763600
Age: embryonic day 2.5
Specimen Label: 8c
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5763420
Assay Type: RT-PCR
Annotation Date: 2016-04-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:5763600
Age: embryonic day 3.0
Specimen Label: morula
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5763420
Assay Type: RT-PCR
Annotation Date: 2016-04-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:5763600
Age: embryonic day 3.5
Specimen Label: blastocyst
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5763420
Assay Type: RT-PCR
Annotation Date: 2016-04-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5763600
Age: embryonic day 9.5
Specimen Label: E9.5
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7408367
Assay Type: RT-PCR
Annotation Date: 2022-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689417
Stage: TS17
Assay Id: MGI:7408397
Age: embryonic day 10.5
Image: S3
Specimen Label: Control
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7408367
Assay Type: RT-PCR
Annotation Date: 2022-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689417
Stage: TS17
Assay Id: MGI:7408397
Age: embryonic day 10.5
Image: S3
Specimen Label: DCKO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7466189
Assay Type: Western blot
Annotation Date: 2023-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:7466418
Age: postnatal day 2
Image: 3
Specimen Label: Control
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7466189
Assay Type: Western blot
Annotation Date: 2023-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:7466418
Age: postnatal day 2
Image: 3
Specimen Label: cKO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7466193
Assay Type: Western blot
Annotation Date: 2023-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:7466421
Age: postnatal day 2
Image: 3
Specimen Label: Control
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7466193
Assay Type: Western blot
Annotation Date: 2023-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:7466421
Age: postnatal day 2
Image: 3
Specimen Label: cKO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7466189
Assay Type: Western blot
Annotation Date: 2023-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672824
Stage: TS24
Assay Id: MGI:7466425
Age: embryonic day 16.5
Image: 3
Specimen Label: Control
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7466189
Assay Type: Western blot
Annotation Date: 2023-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672824
Stage: TS24
Assay Id: MGI:7466425
Age: embryonic day 16.5
Image: 3
Specimen Label: cKO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7466193
Assay Type: Western blot
Annotation Date: 2023-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672824
Stage: TS24
Assay Id: MGI:7466428
Age: embryonic day 16.5
Image: 3
Specimen Label: Control
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7466193
Assay Type: Western blot
Annotation Date: 2023-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672824
Stage: TS24
Assay Id: MGI:7466428
Age: embryonic day 16.5
Image: 3
Specimen Label: cKO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7466189
Assay Type: Western blot
Annotation Date: 2023-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7466798
Age: embryonic day 18.5
Specimen Label: Control
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7466189
Assay Type: Western blot
Annotation Date: 2023-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7466798
Age: embryonic day 18.5
Specimen Label: cKO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7466193
Assay Type: Western blot
Annotation Date: 2023-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7466800
Age: embryonic day 18.5
Specimen Label: Control
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7466193
Assay Type: Western blot
Annotation Date: 2023-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7466800
Age: embryonic day 18.5
Specimen Label: cKO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3505905
Assay Type: RNA in situ
Annotation Date: 2004-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1698217
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3510334
Age: embryonic day 10.5
Image: 3B
Note: Neuroblast/VIII ganglion.
Specimen Label: 3B
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4425739
Assay Type: RNA in situ
Annotation Date: 2023-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7525219
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3505905
Assay Type: RNA in situ
Annotation Date: 2004-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666917
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:3510334
Age: embryonic day 10.5
Image: 3B
Note: Otic vesicle; ventral and/or anteroventral restricted expression.
Specimen Label: 3B
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4425739
Assay Type: RNA in situ
Annotation Date: 2023-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7525219
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3505905
Assay Type: RNA in situ
Annotation Date: 2004-12-06
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1699417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3510334
Age: embryonic day 10.5
Image: 3B
Note: Endolymphatic duct.
Specimen Label: 3B
Detected: true
Specimen Num: 1
•
•
•
•
•
Publication
33630828 | J:306991
First Author: Zhou R
Year: 2021
Journal: PLoS Biol
Title: The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration.
Volume: 19
Issue: 2
Pages: e3001122
•
•
•
•
•
Publication
34060480 | J:307273
 
First Author: Carter P
Year: 2021
Journal: J Clin Invest
Title: Deletion of Lats1/2 in adult kidney epithelia leads to renal cell carcinoma.
Volume: 131
Issue: 11
•
•
•
•
•
Publication
35768444 | J:326521
First Author: Vittoria MA
Year: 2022
Journal: Nat Commun
Title: Inactivation of the Hippo tumor suppressor pathway promotes melanoma.
Volume: 13
Issue: 1
Pages: 3732
•
•
•
•
•
Publication
36395225 | J:331498
First Author: Kowalczyk W
Year: 2022
Journal: Science
Title: Hippo signaling instructs ectopic but not normal organ growth.
Volume: 378
Issue: 6621
Pages: eabg3679
•
•
•
•
•
Publication
29438698 | J:257766
First Author: Wu LMN
Year: 2018
Journal: Cancer Cell
Title: Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis.
Volume: 33
Issue: 2
Pages: 292-308.e7
•
•
•
•
•
Publication
32994166 | J:300520
 
First Author: Vanyai HK
Year: 2020
Journal: Development
Title: Control of skeletal morphogenesis by the Hippo-YAP/TAZ pathway.
Volume: 147
Issue: 21
•
•
•
•
•
Publication
28115535 | J:270351
First Author: Kuroda M
Year: 2017
Journal: J Cell Sci
Title: Vinculin promotes nuclear localization of TAZ to inhibit ECM stiffness-dependent differentiation into adipocytes.
Volume: 130
Issue: 5
Pages: 989-1002
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom