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Search results 1 to 100 out of 161 for Lcp2

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
3937 | LCP2
Type: gene
Organism: human
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Gene
513244 | LCP2
Type: gene
Organism: cattle
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Gene
395438 | LCP2
Type: gene
Organism: chicken
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Gene
700374 | LCP2
Type: gene
Organism: macaque, rhesus
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Gene
100158590 | lcp2
Type: gene
Organism: frog, western clawed
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Gene
155918 | Lcp2
Type: gene
Organism: rat
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Gene
489126 | LCP2
Type: gene
Organism: dog, domestic
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Gene
471734 | LCP2
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1321402 | Lcp2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
19380761 | J:147721
First Author: Bezman NA
Year: 2009
Journal: J Immunol
Title: Cutting edge: rescue of pre-TCR but not mature TCR signaling in mice expressing membrane-targeted SLP-76.
Volume: 182
Issue: 9
Pages: 5183-7
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Publication
25662996 | J:223524
First Author: Siggs OM
Year: 2015
Journal: J Immunol
Title: Quantitative reduction of the TCR adapter protein SLP-76 unbalances immunity and immune regulation.
Volume: 194
Issue: 6
Pages: 2587-95
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Publication
20029045 | J:158131
First Author: Sonnenberg GF
Year: 2010
Journal: Blood
Title: Mislocalization of SLP-76 leads to aberrant inflammatory cytokine and autoantibody production.
Volume: 115
Issue: 11
Pages: 2186-95
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Protein Coding Gene
MGP_CAROLIEiJ_G0016200 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018149 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018122 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018086 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018091 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017904 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1321402 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018545 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017468 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017877 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017987 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017981 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018059 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018005 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018584 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017249 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017517 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017336 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017041 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
19667077 | J:153901
First Author: Baker RG
Year: 2009
Journal: Mol Cell Biol
Title: The adapter protein SLP-76 mediates "outside-in" integrin signaling and function in T cells.
Volume: 29
Issue: 20
Pages: 5578-89
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Publication
16186188 | J:107467
First Author: Maltzman JS
Year: 2005
Journal: J Exp Med
Title: Conditional deletion reveals a cell-autonomous requirement of SLP-76 for thymocyte selection.
Volume: 202
Issue: 7
Pages: 893-900
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Publication
25929249 | J:229762
First Author: Lampe K
Year: 2015
Journal: Eur J Immunol
Title: Slp-76 is a critical determinant of NK-cell mediated recognition of missing-self targets.
Volume: 45
Issue: 7
Pages: 2072-83
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Publication
24307208 | J:209305
First Author: Caton AJ
Year: 2014
Journal: Eur J Immunol
Title: Strength of TCR signal from self-peptide modulates autoreactive thymocyte deletion and Foxp3(+) Treg-cell formation.
Volume: 44
Issue: 3
Pages: 785-93
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Publication
18663126 | J:139532
First Author: Bezman NA
Year: 2008
Journal: J Exp Med
Title: Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo.
Volume: 205
Issue: 8
Pages: 1775-88
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Publication
21725281 | J:175902
First Author: Sela M
Year: 2011
Journal: EMBO J
Title: Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells.
Volume: 30
Issue: 15
Pages: 3160-72
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Publication
9665885 | J:76697
First Author: Clements JL
Year: 1998
Journal: Science
Title: Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development.
Volume: 281
Issue: 5375
Pages: 416-9
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Publication
17965338 | J:131225
First Author: Ramsey K
Year: 2008
Journal: J Leukoc Biol
Title: Impaired thymic selection in mice expressing altered levels of the SLP-76 adaptor protein.
Volume: 83
Issue: 2
Pages: 419-29
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Publication
11050236 | J:65381
First Author: Judd BA
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Hematopoietic reconstitution of SLP-76 corrects hemostasis and platelet signaling through alpha IIb beta 3 and collagen receptors.
Volume: 97
Issue: 22
Pages: 12056-61
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Publication
10427985 | J:56584
First Author: Peterson EJ
Year: 1999
Journal: Eur J Immunol
Title: NK cytokine secretion and cytotoxicity occur independently of the SLP-76 adaptor protein.
Volume: 29
Issue: 7
Pages: 2223-32
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Publication
22806433 | J:188001
First Author: Lee D
Year: 2012
Journal: Eur J Immunol
Title: SLP-76 is required for optimal CXCR4-stimulated T lymphocyte firm arrest to ICAM-1 under shear flow.
Volume: 42
Issue: 10
Pages: 2736-43
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Publication
9695951 | J:48828
First Author: Pivniouk V
Year: 1998
Journal: Cell
Title: Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.
Volume: 94
Issue: 2
Pages: 229-38
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Publication
11792851 | J:127031
First Author: Kumar L
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Differential role of SLP-76 domains in T cell development and function.
Volume: 99
Issue: 2
Pages: 884-9
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Publication
10377180 | J:119608
First Author: Pivniouk VI
Year: 1999
Journal: J Clin Invest
Title: SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells.
Volume: 103
Issue: 12
Pages: 1737-43
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Publication
25672755 | J:223523
First Author: Hillen KM
Year: 2015
Journal: J Immunol
Title: T cell expansion is the limiting factor of virus control in mice with attenuated TCR signaling: implications for human immunodeficiency.
Volume: 194
Issue: 6
Pages: 2725-34
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Publication
20080760 | J:156520
First Author: Bushar ND
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Ablation of SLP-76 signaling after T cell priming generates memory CD4 T cells impaired in steady-state and cytokine-driven homeostasis.
Volume: 107
Issue: 2
Pages: 827-31
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Publication
15668918 | J:95616
First Author: Mizuno K
Year: 2005
Journal: Eur J Immunol
Title: SLP-76 is recruited to CD22 and dephosphorylated by SHP-1, thereby regulating B cell receptor-induced c-Jun N-terminal kinase activation.
Volume: 35
Issue: 2
Pages: 644-54
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Publication
11754821 | J:110507
First Author: Myung PS
Year: 2001
Journal: Immunity
Title: Differential requirement for SLP-76 domains in T cell development and function.
Volume: 15
Issue: 6
Pages: 1011-26
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Publication
16456002 | J:129190
First Author: Jordan MS
Year: 2006
Journal: J Immunol
Title: Functional hierarchy of the N-terminal tyrosines of SLP-76.
Volume: 176
Issue: 4
Pages: 2430-8
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Publication
28107427 | J:246908
First Author: Navas VH
Year: 2017
Journal: PLoS One
Title: Serine Phosphorylation of SLP76 Is Dispensable for T Cell Development but Modulates Helper T Cell Function.
Volume: 12
Issue: 1
Pages: e0170396
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GXD Expression
GXD Expression
 
Probe: MGI:1438445
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825889
Age: embryonic day 14.5
Image: euxassay_003585_12
Specimen Label: euxassay_003585_12
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1438445
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825889
Age: embryonic day 14.5
Image: euxassay_003585_13
Specimen Label: euxassay_003585_13
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1438445
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825889
Age: embryonic day 14.5
Image: euxassay_003585_14
Specimen Label: euxassay_003585_14
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:1438445
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825889
Age: embryonic day 14.5
Image: euxassay_003585_15
Specimen Label: euxassay_003585_15
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:1438445
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825889
Age: embryonic day 14.5
Image: euxassay_003585_16
Specimen Label: euxassay_003585_16
Detected: true
Specimen Num: 5
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Publication
19074136 | J:147595
First Author: Chiang YJ
Year: 2009
Journal: J Biol Chem
Title: Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation.
Volume: 284
Issue: 7
Pages: 4429-38
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Publication
18342008 | J:132995
First Author: Jordan MS
Year: 2008
Journal: Immunity
Title: Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76.
Volume: 28
Issue: 3
Pages: 359-69
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Publication
21949020 | J:179442
First Author: Burns JC
Year: 2011
Journal: J Immunol
Title: The SLP-76 Src homology 2 domain is required for T cell development and activation.
Volume: 187
Issue: 9
Pages: 4459-66
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Publication
22623329 | J:188957
First Author: Zou T
Year: 2012
Journal: J Immunol
Title: Cutting edge: IL-2 signals determine the degree of TCR signaling necessary to support regulatory T cell proliferation in vivo.
Volume: 189
Issue: 1
Pages: 28-32
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Publication
23162753 | J:196519
First Author: Cashman S
Year: 2012
Journal: Oncoimmunology
Title: An ENU mutagenesis approach to dissect "self"-induced immune responses: Unraveling the genetic footprint of immunosurveillance.
Volume: 1
Issue: 6
Pages: 856-862
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Publication
20847203 | J:167402
First Author: Smith-Garvin JE
Year: 2010
Journal: Blood
Title: T-cell receptor signals direct the composition and function of the memory CD8+ T-cell pool.
Volume: 116
Issue: 25
Pages: 5548-59
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Publication
20884806 | J:167386
First Author: Wiehagen KR
Year: 2010
Journal: Blood
Title: Loss of tonic T-cell receptor signals alters the generation but not the persistence of CD8+ memory T cells.
Volume: 116
Issue: 25
Pages: 5560-70
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Publication
14694181 | J:88628
First Author: Nichols KE
Year: 2004
Journal: J Leukoc Biol
Title: Macrophage activation and Fcgamma receptor-mediated signaling do not require expression of the SLP-76 and SLP-65 adaptors.
Volume: 75
Issue: 3
Pages: 541-52
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Publication
15153494 | J:90531
First Author: Wu JN
Year: 2004
Journal: J Immunol
Title: Differential requirement for adapter proteins Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and adhesion- and degranulation-promoting adapter protein in FcepsilonRI signaling and mast cell function.
Volume: 172
Issue: 11
Pages: 6768-74
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Publication
22344272 | J:181643
First Author: Corbo-Rodgers E
Year: 2012
Journal: Nat Immunol
Title: Oral ivermectin as an unexpected initiator of CreT2-mediated deletion in T cells.
Volume: 13
Issue: 3
Pages: 197-8
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Publication
16950126 | J:112805
First Author: Sebzda E
Year: 2006
Journal: Dev Cell
Title: Syk and Slp-76 mutant mice reveal a cell-autonomous hematopoietic cell contribution to vascular development.
Volume: 11
Issue: 3
Pages: 349-61
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Publication
16943434 | J:112305
First Author: Abtahian F
Year: 2006
Journal: Mol Cell Biol
Title: Evidence for the requirement of ITAM domains but not SLP-76/Gads interaction for integrin signaling in hematopoietic cells.
Volume: 26
Issue: 18
Pages: 6936-49
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Publication
16354835 | J:104696
First Author: Kumar L
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: A 10-aa-long sequence in SLP-76 upstream of the Gads binding site is essential for T cell development and function.
Volume: 102
Issue: 52
Pages: 19063-8
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Publication
22956580 | J:190737
First Author: Corbo-Rodgers E
Year: 2012
Journal: J Immunol
Title: Homeostatic division is not necessary for antigen-specific CD4+ memory T cell persistence.
Volume: 189
Issue: 7
Pages: 3378-85
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Publication
11239162 | J:76696
First Author: Yoder J
Year: 2001
Journal: Science
Title: Requirement for the SLP-76 adaptor GADS in T cell development.
Volume: 291
Issue: 5510
Pages: 1987-91
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Publication
15477347 | J:94914
First Author: Wang H
Year: 2004
Journal: J Exp Med
Title: ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation.
Volume: 200
Issue: 8
Pages: 1063-74
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Publication
11841396 | J:74458
First Author: Geng L
Year: 2002
Journal: Br J Haematol
Title: Signalling scaffolds and adaptors in T-cell immunity.
Volume: 116
Issue: 1
Pages: 19-27
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Publication
10712938 | J:61029
First Author: Pivniouk VI
Year: 2000
Journal: Curr Opin Immunol
Title: The role of SLP-76 and LAT in lymphocyte development.
Volume: 12
Issue: 2
Pages: 173-8
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Publication
16273097 | J:112654
First Author: Yokosuka T
Year: 2005
Journal: Nat Immunol
Title: Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.
Volume: 6
Issue: 12
Pages: 1253-62
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Publication
26321253 | J:228091
First Author: Liu H
Year: 2015
Journal: Mol Cell
Title: The Immune Adaptor SLP-76 Binds to SUMO-RANGAP1 at Nuclear Pore Complex Filaments to Regulate Nuclear Import of Transcription Factors in T Cells.
Volume: 59
Issue: 5
Pages: 840-9
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Publication
23901140 | J:260309
First Author: Smith X
Year: 2013
Journal: Sci Signal
Title: The chemokine CXCL12 generates costimulatory signals in T cells to enhance phosphorylation and clustering of the adaptor protein SLP-76.
Volume: 6
Issue: 286
Pages: ra65
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Publication
7706237 | J:24168
First Author: Jackman JK
Year: 1995
Journal: J Biol Chem
Title: Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells.
Volume: 270
Issue: 13
Pages: 7029-32
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Publication
19401562 | J:150304
First Author: Shen S
Year: 2009
Journal: Blood
Title: The importance of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kilodaltons sterile-alpha motif domain in thymic selection and T-cell activation.
Volume: 114
Issue: 1
Pages: 74-84
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Publication
20516645 | J:163722
First Author: Liu X
Year: 2010
Journal: J Clin Invest
Title: Distinct roles for PTEN in prevention of T cell lymphoma and autoimmunity in mice.
Volume: 120
Issue: 7
Pages: 2497-507
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Publication
27349342 | J:246640
First Author: Danzer C
Year: 2016
Journal: Eur J Immunol
Title: A mutation within the SH2 domain of slp-76 regulates the tissue distribution and cytokine production of iNKT cells in mice.
Volume: 46
Issue: 9
Pages: 2121-36
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Publication
33436632 | J:300870
First Author: Yan Z
Year: 2021
Journal: Nat Commun
Title: Targeting adaptor protein SLP76 of RAGE as a therapeutic approach for lethal sepsis.
Volume: 12
Issue: 1
Pages: 308
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Publication
11901197 | J:75708
First Author: Judd BA
Year: 2002
Journal: J Exp Med
Title: Differential requirement for LAT and SLP-76 in GPVI versus T cell receptor signaling.
Volume: 195
Issue: 6
Pages: 705-17
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Publication
9884330 | J:51934
First Author: Clements JL
Year: 1999
Journal: J Clin Invest
Title: Fetal hemorrhage and platelet dysfunction in SLP-76-deficient mice.
Volume: 103
Issue: 1
Pages: 19-25
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Publication
10747096 | J:156075
First Author: Krause M
Year: 2000
Journal: J Cell Biol
Title: Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton.
Volume: 149
Issue: 1
Pages: 181-94
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Publication
17372019 | J:145136
First Author: Clemens RA
Year: 2007
Journal: J Immunol
Title: Loss of SLP-76 expression within myeloid cells confers resistance to neutrophil-mediated tissue damage while maintaining effective bacterial killing.
Volume: 178
Issue: 7
Pages: 4606-14
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Publication
20363774 | J:162815
First Author: Bertozzi CC
Year: 2010
Journal: Blood
Title: Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling.
Volume: 116
Issue: 4
Pages: 661-70
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Publication
23348738 | J:194487
First Author: Boulaftali Y
Year: 2013
Journal: J Clin Invest
Title: Platelet ITAM signaling is critical for vascular integrity in inflammation.
Volume: 123
Issue: 2
Pages: 908-16
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Publication
20606011 | J:163285
First Author: Kambayashi T
Year: 2010
Journal: Mol Cell Biol
Title: Independent and cooperative roles of adaptor molecules in proximal signaling during FcepsilonRI-mediated mast cell activation.
Volume: 30
Issue: 17
Pages: 4188-96
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Publication
32153566 | J:312578
 
First Author: Raynor J
Year: 2020
Journal: Front Immunol
Title: The Variable Genomic NK Cell Receptor Locus Is a Key Determinant of CD4+ T Cell Responses During Viral Infection.
Volume: 11
Pages: 197
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Publication
25821220 | J:236699
First Author: Schmidt AM
Year: 2015
Journal: J Immunol
Title: Regulatory T cells require TCR signaling for their suppressive function.
Volume: 194
Issue: 9
Pages: 4362-70
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Publication
20957749 | J:166154
First Author: Patzak IM
Year: 2010
Journal: Eur J Immunol
Title: HPK1 competes with ADAP for SLP-76 binding and via Rap1 negatively affects T-cell adhesion.
Volume: 40
Issue: 11
Pages: 3220-5
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Publication
12351393 | J:115518
First Author: Leo L
Year: 2002
Journal: Blood
Title: Role of the adapter protein SLP-76 in GPVI-dependent platelet procoagulant responses to collagen.
Volume: 100
Issue: 8
Pages: 2839-44
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Publication
23407547 | J:196459
First Author: May RM
Year: 2013
Journal: Blood
Title: Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function.
Volume: 121
Issue: 16
Pages: 3135-46
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Publication
21497118 | J:171335
First Author: Chang JT
Year: 2011
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