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Search results 1 to 100 out of 401 for Ldha

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
3939 | LDHA
Type: gene
Organism: human
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Gene
394758 | ldha
Type: gene
Organism: frog, western clawed
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Gene
451063 | LDHA
Type: gene
Organism: chimpanzee
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Gene
281274 | LDHA
Type: gene
Organism: cattle
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Gene
key_19971 | LDHA
Type: gene
Organism: lemur, mouse
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Gene
key_36141 | LDHA
Type: gene
Organism: cat, domestic
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Gene
key_19515 | LDHA
Type: gene
Organism: pig, domestic
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Gene
key_19411 | LDHA
Type: gene
Organism: rabbit, European
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Gene
24533 | Ldha
Type: gene
Organism: rat
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Gene
476882 | LDHA
Type: gene
Organism: dog, domestic
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Gene
396221 | LDHA
Type: gene
Organism: chicken
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Gene
30496 | ldha
Type: gene
Organism: zebrafish
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Gene
694309 | LDHA
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:96759 | Ldha
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
35176139 | J:326167
First Author: Chen Q
Year: 2022
Journal: Blood
Title: Inhibition of LDHA to induce eEF2 release enhances thrombocytopoiesis.
Volume: 139
Issue: 19
Pages: 2958-2971
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Gene
131840634 | GLTC1
Type: gene
Organism: human
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Publication
8662241 | J:33596
First Author: Schmutz SM
Year: 1996
Journal: Mamm Genome
Title: In situ hybridization mapping of LDHA and IGF2 to cattle chromosome 29.
Volume: 7
Issue: 6
Pages: 473
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Publication
39033542 | J:360967
First Author: Ma H
Year: 2024
Journal: Adv Sci (Weinh)
Title: Gasdermin D Mediated Mitochondrial Metabolism Orchestrate Neurogenesis Through LDHA During Embryonic Development.
Volume: 11
Issue: 35
Pages: e2402285
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Publication
9457676 | J:45877
First Author: Pretsch W
Year: 1998
Journal: Mamm Genome
Title: Molecular, genetic and biochemical characterization of lactate dehydrogenase-A enzyme activity mutations in Mus musculus.
Volume: 9
Issue: 2
Pages: 144-9
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Publication
22438825 | J:183477
First Author: Nilsson LM
Year: 2012
Journal: PLoS Genet
Title: Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis.
Volume: 8
Issue: 3
Pages: e1002573
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Publication
39055955 | J:350095
First Author: Frame AK
Year: 2024
Journal: iScience
Title: Altered neuronal lactate dehydrogenase A expression affects cognition in a sex- and age-dependent manner.
Volume: 27
Issue: 7
Pages: 110342
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Publication
7247935 | J:6530
First Author: Charles DJ
Year: 1981
Journal: Biochem Genet
Title: A mutation affecting the lactate dehydrogenase locus Ldh-1 in the mouse-I. Genetical and electrophoretical characterization.
Volume: 19
Issue: 3-4
Pages: 301-9
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Publication
3595765 | J:132674
First Author: Kremer JP
Year: 1987
Journal: Exp Hematol
Title: Mechanisms of compensation of hemolytic anemia in a lactate dehydrogenase mouse mutant.
Volume: 15
Issue: 6
Pages: 664-70
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Publication
8224816 | J:14326
First Author: Pretsch W
Year: 1993
Journal: Genetics
Title: A mutation affecting the lactate dehydrogenase locus Ldh-1 in the mouse. II. Mechanism of the LDH-A deficiency associated with hemolytic anemia.
Volume: 135
Issue: 1
Pages: 161-70
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Publication
7534515 | J:22177
First Author: Sandulache R
Year: 1994
Journal: Mamm Genome
Title: Molecular analysis of four lactate dehydrogenase-A mutants in the mouse.
Volume: 5
Issue: 12
Pages: 777-80
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Protein
Q6NXW3
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: false
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Publication
2744450 | J:9873
First Author: Pretsch W
Year: 1989
Journal: Genet Res
Title: Eight independent Ldh-1 mutations of the mouse recovered in mutagenicity experiments: biochemical characteristics and chromosomal localization.
Volume: 53
Issue: 2
Pages: 101-4
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Publication
32877669 | J:323571
First Author: Dai C
Year: 2020
Journal: Cell Rep
Title: Lactate Dehydrogenase A Governs Cardiac Hypertrophic Growth in Response to Hemodynamic Stress.
Volume: 32
Issue: 9
Pages: 108087
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Publication
27641098 | J:251926
First Author: Brand A
Year: 2016
Journal: Cell Metab
Title: LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.
Volume: 24
Issue: 5
Pages: 657-671
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Publication
14581519 | J:86337
First Author: Olsson PG
Year: 2003
Journal: J Androl
Title: Abundance of repetitive sequence elements in the mouse testis-specific lactate dehydrogenase-C gene.
Volume: 24
Issue: 6
Pages: 918-20
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Publication
36759610 | J:335012
First Author: Yao S
Year: 2023
Journal: Nat Commun
Title: Astrocytic lactate dehydrogenase A regulates neuronal excitability and depressive-like behaviors through lactate homeostasis in mice.
Volume: 14
Issue: 1
Pages: 729
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Publication
36552300 | J:358595
 
First Author: Zhang XN
Year: 2022
Journal: Biology (Basel)
Title: Ldha-Dependent Metabolic Programs in Sertoli Cells Regulate Spermiogenesis in Mouse Testis.
Volume: 11
Issue: 12
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Publication
32123114 | J:286769
First Author: Hermans D
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8+ T cell stemness and antitumor immunity.
Volume: 117
Issue: 11
Pages: 6047-6055
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Publication
35714859 | J:326832
     
First Author: Serra M
Year: 2022
Journal: Cell Mol Gastroenterol Hepatol
Title: Deletion of Lactate Dehydrogenase-A Impairs Oncogene-Induced Mouse Hepatocellular Carcinoma Development.
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Publication
36057161 | J:344150
 
First Author: Chen Y
Year: 2022
Journal: Redox Biol
Title: LDHA-mediated metabolic reprogramming promoted cardiomyocyte proliferation by alleviating ROS and inducing M2 macrophage polarization.
Volume: 56
Pages: 102446
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Publication
39159042 | J:353574
First Author: Gubser PM
Year: 2024
Journal: Cell Rep
Title: Aerobic glycolysis but not GLS1-dependent glutamine metabolism is critical for anti-tumor immunity and response to checkpoint inhibition.
Volume: 43
Issue: 8
Pages: 114632
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Publication
33979589 | J:314461
First Author: Xu K
Year: 2021
Journal: Immunity
Title: Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses.
Volume: 54
Issue: 5
Pages: 976-987.e7
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Publication
33479154 | J:301027
First Author: Xu K
Year: 2021
Journal: Science
Title: Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity.
Volume: 371
Issue: 6527
Pages: 405-410
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Publication
36064857 | J:328341
First Author: Feng T
Year: 2022
Journal: Nat Commun
Title: Adipocyte-derived lactate is a signalling metabolite that potentiates adipose macrophage inflammation via targeting PHD2.
Volume: 13
Issue: 1
Pages: 5208
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Publication
36821379 | J:353321
 
First Author: Hu Z
Year: 2023
Journal: J Clin Invest
Title: Glycolysis drives STING signaling to facilitate dendritic cell antitumor function.
Volume: 133
Issue: 7
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Publication
38443336 | J:351967
First Author: Khan F
Year: 2024
Journal: Nat Commun
Title: Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression.
Volume: 15
Issue: 1
Pages: 1987
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Publication
27708054 | J:314934
First Author: Peng M
Year: 2016
Journal: Science
Title: Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism.
Volume: 354
Issue: 6311
Pages: 481-484
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Publication
38363844 | J:345408
First Author: Pv A
Year: 2024
Journal: Sci Adv
Title: Glycolytic state of aortic endothelium favors hematopoietic transition during the emergence of definitive hematopoiesis.
Volume: 10
Issue: 7
Pages: eadh8478
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Publication
32647171 | J:292290
First Author: Arra M
Year: 2020
Journal: Nat Commun
Title: LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis.
Volume: 11
Issue: 1
Pages: 3427
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Publication
35366539 | J:326715
 
First Author: Minemura T
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Lactate dehydrogenase regulates basal glucose uptake in adipocytes.
Volume: 607
Pages: 20-27
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Publication
36961904 | J:334936
First Author: Chen X
Year: 2023
Journal: Sci Adv
Title: The lactate dehydrogenase (LDH) isoenzyme spectrum enables optimally controlling T cell glycolysis and differentiation.
Volume: 9
Issue: 12
Pages: eadd9554
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Publication
38168955 | J:344204
First Author: Zou D
Year: 2024
Journal: Nat Immunol
Title: CD4(+) T cell immunity is dependent on an intrinsic stem-like program.
Volume: 25
Issue: 1
Pages: 66-76
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Publication
38587131 | J:350558
First Author: Späte E
Year: 2024
Journal: Glia
Title: Downregulated expression of lactate dehydrogenase in adult oligodendrocytes and its implication for the transfer of glycolysis products to axons.
Volume: 72
Issue: 8
Pages: 1374-1391
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Protein Coding Gene
MGP_CAROLIEiJ_G0029771 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032274 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032253 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032189 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032265 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031978 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_96759 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032755 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031306 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031943 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032100 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032054 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032181 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032091 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032772 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031029 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031426 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0012996 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030869 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
3036647 | J:8748
First Author: Fukasawa KM
Year: 1987
Journal: Genetics
Title: Complete nucleotide sequence of the mouse lactate dehydrogenase-A functional gene: comparison of the exon-intron organization of dehydrogenase genes.
Volume: 116
Issue: 1
Pages: 99-105
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Publication
3996406 | J:7855
First Author: Li SS
Year: 1985
Journal: Eur J Biochem
Title: Protein structure and gene organization of mouse lactate dehydrogenase-A isozyme.
Volume: 149
Issue: 2
Pages: 215-25
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Publication
24726384 | J:214778
First Author: Xie H
Year: 2014
Journal: Cell Metab
Title: Targeting lactate dehydrogenase--a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells.
Volume: 19
Issue: 5
Pages: 795-809
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Publication
- | J:13739
 
First Author: Soares ER
Year: 1977
Journal: Mouse News Lett
Title: LDH
Volume: 57
Pages: 33
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Publication
1644279 | J:1072
First Author: Merkle S
Year: 1992
Journal: Genetics
Title: Hereditary lactate dehydrogenase A-subunit deficiency as cause of early postimplantation death of homozygotes in Mus musculus.
Volume: 131
Issue: 2
Pages: 413-21
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Publication
1520254 | J:506
First Author: Merkle S
Year: 1992
Journal: Biochem Genet
Title: Characterization of two electrophoretic lactate dehydrogenase-A mutants in Mus musculus.
Volume: 30
Issue: 1-2
Pages: 49-59
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Publication
648198 | J:5978
First Author: O'Brien D
Year: 1978
Journal: Cytogenet Cell Genet
Title: Assignment of the gene for lactic dehydrogenase A to mouse chromosome 7 using mouse-human hybrids.
Volume: 21
Issue: 1-2
Pages: 72-6
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Publication
9370117 | J:44353
First Author: Rathour NP
Year: 1997
Journal: Horm Metab Res
Title: Changes in LDH isozyme pattern in uterine fluid of mice during early pregnancy.
Volume: 29
Issue: 9
Pages: 462-4
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GXD Expression
GXD Expression
     
Probe: MGI:4939220
Assay Type: RT-PCR
Annotation Date: 2011-03-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737326
Stage: TS26
Assay Id: MGI:4939421
Age: embryonic day 18.5
Specimen Label: Wild-type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4939220
Assay Type: RT-PCR
Annotation Date: 2011-03-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737326
Stage: TS26
Assay Id: MGI:4939421
Age: embryonic day 18.5
Specimen Label: Vangl2Lp/Lp
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7546867
Assay Type: Western blot
Annotation Date: 2023-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550526
Stage: TS26
Assay Id: MGI:7546936
Age: embryonic day 18.5
Image: 5
Specimen Label: WT1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7546867
Assay Type: Western blot
Annotation Date: 2023-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550526
Stage: TS26
Assay Id: MGI:7546936
Age: embryonic day 18.5
Image: 5
Specimen Label: WT2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7546867
Assay Type: Western blot
Annotation Date: 2023-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550526
Stage: TS26
Assay Id: MGI:7546936
Age: embryonic day 18.5
Image: 5
Specimen Label: CKO1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7546867
Assay Type: Western blot
Annotation Date: 2023-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550526
Stage: TS26
Assay Id: MGI:7546936
Age: embryonic day 18.5
Image: 5
Specimen Label: CKO2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7546906
Assay Type: RT-PCR
Annotation Date: 2023-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550526
Stage: TS26
Assay Id: MGI:7546963
Age: embryonic day 18.5
Image: 5
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7546906
Assay Type: RT-PCR
Annotation Date: 2023-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550526
Stage: TS26
Assay Id: MGI:7546963
Age: embryonic day 18.5
Image: 5
Specimen Label: CKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7616323
Age: embryonic day 13.5
Specimen Label: 13.5 dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7616323
Age: embryonic day 13.5
Specimen Label: 13.5 dpc
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7616323
Age: embryonic day 13.5
Specimen Label: 13.5 dpc
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:7616323
Age: embryonic day 16.5
Specimen Label: 16.5 dpc
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:7616323
Age: embryonic day 16.5
Specimen Label: 16.5 dpc
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:7616323
Age: embryonic day 16.5
Specimen Label: 16.5 dpc
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7616323
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7616323
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7616323
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3679328
Stage: TS28
Assay Id: MGI:7616323
Age: postnatal week 8
Specimen Label: 8 weeks
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3679328
Stage: TS28
Assay Id: MGI:7616323
Age: postnatal week 8
Specimen Label: 8 weeks
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3679328
Stage: TS28
Assay Id: MGI:7616323
Age: postnatal week 8
Specimen Label: 8 weeks
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7711762
Assay Type: RT-PCR
Annotation Date: 2024-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610526
Stage: TS26
Assay Id: MGI:7711871
Age: embryonic day 19.5
Specimen Label: WT E19.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7711762
Assay Type: RT-PCR
Annotation Date: 2024-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610526
Stage: TS26
Assay Id: MGI:7711871
Age: embryonic day 19.5
Specimen Label: S187A E19.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7711762
Assay Type: RT-PCR
Annotation Date: 2024-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7711871
Age: postnatal day 1
Specimen Label: WT P1
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7711762
Assay Type: RT-PCR
Annotation Date: 2024-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7711871
Age: postnatal day 1
Specimen Label: S187A P1
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7711772
Assay Type: RT-PCR
Annotation Date: 2024-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:7712199
Age: embryonic day 12.5
Image: S4
Specimen Label: Ctrl
Detected: true
Specimen Num: 1
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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