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Search results 1 to 100 out of 365 for Ldha

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: lemur, mouse
Gene
Type: gene
Organism: cat, domestic
Gene
Type: gene
Organism: pig, domestic
Gene
Type: gene
Organism: rabbit, European
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Chen Q
Year: 2022
Journal: Blood
Title: Inhibition of LDHA to induce eEF2 release enhances thrombocytopoiesis.
Volume: 139
Issue: 19
Pages: 2958-2971
Gene
Type: gene
Organism: human
Publication
First Author: Schmutz SM
Year: 1996
Journal: Mamm Genome
Title: In situ hybridization mapping of LDHA and IGF2 to cattle chromosome 29.
Volume: 7
Issue: 6
Pages: 473
Publication
First Author: Pretsch W
Year: 1998
Journal: Mamm Genome
Title: Molecular, genetic and biochemical characterization of lactate dehydrogenase-A enzyme activity mutations in Mus musculus.
Volume: 9
Issue: 2
Pages: 144-9
Publication
First Author: Nilsson LM
Year: 2012
Journal: PLoS Genet
Title: Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis.
Volume: 8
Issue: 3
Pages: e1002573
Publication
First Author: Charles DJ
Year: 1981
Journal: Biochem Genet
Title: A mutation affecting the lactate dehydrogenase locus Ldh-1 in the mouse-I. Genetical and electrophoretical characterization.
Volume: 19
Issue: 3-4
Pages: 301-9
Publication
First Author: Pretsch W
Year: 1993
Journal: Genetics
Title: A mutation affecting the lactate dehydrogenase locus Ldh-1 in the mouse. II. Mechanism of the LDH-A deficiency associated with hemolytic anemia.
Volume: 135
Issue: 1
Pages: 161-70
Publication
First Author: Sandulache R
Year: 1994
Journal: Mamm Genome
Title: Molecular analysis of four lactate dehydrogenase-A mutants in the mouse.
Volume: 5
Issue: 12
Pages: 777-80
Publication
First Author: Kremer JP
Year: 1987
Journal: Exp Hematol
Title: Mechanisms of compensation of hemolytic anemia in a lactate dehydrogenase mouse mutant.
Volume: 15
Issue: 6
Pages: 664-70
Publication
First Author: Pretsch W
Year: 1989
Journal: Genet Res
Title: Eight independent Ldh-1 mutations of the mouse recovered in mutagenicity experiments: biochemical characteristics and chromosomal localization.
Volume: 53
Issue: 2
Pages: 101-4
Protein
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: false
Publication
First Author: Dai C
Year: 2020
Journal: Cell Rep
Title: Lactate Dehydrogenase A Governs Cardiac Hypertrophic Growth in Response to Hemodynamic Stress.
Volume: 32
Issue: 9
Pages: 108087
Publication
First Author: Brand A
Year: 2016
Journal: Cell Metab
Title: LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.
Volume: 24
Issue: 5
Pages: 657-671
Publication
First Author: Olsson PG
Year: 2003
Journal: J Androl
Title: Abundance of repetitive sequence elements in the mouse testis-specific lactate dehydrogenase-C gene.
Volume: 24
Issue: 6
Pages: 918-20
Publication
First Author: Yao S
Year: 2023
Journal: Nat Commun
Title: Astrocytic lactate dehydrogenase A regulates neuronal excitability and depressive-like behaviors through lactate homeostasis in mice.
Volume: 14
Issue: 1
Pages: 729
Publication
First Author: Hermans D
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8+ T cell stemness and antitumor immunity.
Volume: 117
Issue: 11
Pages: 6047-6055
Publication      
First Author: Serra M
Year: 2022
Journal: Cell Mol Gastroenterol Hepatol
Title: Deletion of Lactate Dehydrogenase-A Impairs Oncogene-Induced Mouse Hepatocellular Carcinoma Development.
Publication  
First Author: Chen Y
Year: 2022
Journal: Redox Biol
Title: LDHA-mediated metabolic reprogramming promoted cardiomyocyte proliferation by alleviating ROS and inducing M2 macrophage polarization.
Volume: 56
Pages: 102446
Publication
First Author: Xu K
Year: 2021
Journal: Immunity
Title: Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses.
Volume: 54
Issue: 5
Pages: 976-987.e7
Publication
First Author: Xu K
Year: 2021
Journal: Science
Title: Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity.
Volume: 371
Issue: 6527
Pages: 405-410
Publication
First Author: Feng T
Year: 2022
Journal: Nat Commun
Title: Adipocyte-derived lactate is a signalling metabolite that potentiates adipose macrophage inflammation via targeting PHD2.
Volume: 13
Issue: 1
Pages: 5208
Publication
First Author: Peng M
Year: 2016
Journal: Science
Title: Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism.
Volume: 354
Issue: 6311
Pages: 481-484
Publication
First Author: Pv A
Year: 2024
Journal: Sci Adv
Title: Glycolytic state of aortic endothelium favors hematopoietic transition during the emergence of definitive hematopoiesis.
Volume: 10
Issue: 7
Pages: eadh8478
Publication  
First Author: Minemura T
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Lactate dehydrogenase regulates basal glucose uptake in adipocytes.
Volume: 607
Pages: 20-27
Publication
First Author: Chen X
Year: 2023
Journal: Sci Adv
Title: The lactate dehydrogenase (LDH) isoenzyme spectrum enables optimally controlling T cell glycolysis and differentiation.
Volume: 9
Issue: 12
Pages: eadd9554
Publication
First Author: Zou D
Year: 2024
Journal: Nat Immunol
Title: CD4(+) T cell immunity is dependent on an intrinsic stem-like program.
Volume: 25
Issue: 1
Pages: 66-76
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Fukasawa KM
Year: 1987
Journal: Genetics
Title: Complete nucleotide sequence of the mouse lactate dehydrogenase-A functional gene: comparison of the exon-intron organization of dehydrogenase genes.
Volume: 116
Issue: 1
Pages: 99-105
Publication
First Author: Li SS
Year: 1985
Journal: Eur J Biochem
Title: Protein structure and gene organization of mouse lactate dehydrogenase-A isozyme.
Volume: 149
Issue: 2
Pages: 215-25
Publication
First Author: Xie H
Year: 2014
Journal: Cell Metab
Title: Targeting lactate dehydrogenase--a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells.
Volume: 19
Issue: 5
Pages: 795-809
Publication
First Author: Merkle S
Year: 1992
Journal: Genetics
Title: Hereditary lactate dehydrogenase A-subunit deficiency as cause of early postimplantation death of homozygotes in Mus musculus.
Volume: 131
Issue: 2
Pages: 413-21
Publication
First Author: Merkle S
Year: 1992
Journal: Biochem Genet
Title: Characterization of two electrophoretic lactate dehydrogenase-A mutants in Mus musculus.
Volume: 30
Issue: 1-2
Pages: 49-59
Publication  
First Author: Soares ER
Year: 1977
Journal: Mouse News Lett
Title: LDH
Volume: 57
Pages: 33
Publication
First Author: O'Brien D
Year: 1978
Journal: Cytogenet Cell Genet
Title: Assignment of the gene for lactic dehydrogenase A to mouse chromosome 7 using mouse-human hybrids.
Volume: 21
Issue: 1-2
Pages: 72-6
Publication
First Author: Rathour NP
Year: 1997
Journal: Horm Metab Res
Title: Changes in LDH isozyme pattern in uterine fluid of mice during early pregnancy.
Volume: 29
Issue: 9
Pages: 462-4
GXD Expression      
Probe: MGI:4939220
Assay Type: RT-PCR
Annotation Date: 2011-03-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737326
Stage: TS26
Assay Id: MGI:4939421
Age: embryonic day 18.5
Specimen Label: Wild-type
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4939220
Assay Type: RT-PCR
Annotation Date: 2011-03-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737326
Stage: TS26
Assay Id: MGI:4939421
Age: embryonic day 18.5
Specimen Label: Vangl2Lp/Lp
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7546867
Assay Type: Western blot
Annotation Date: 2023-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550526
Stage: TS26
Assay Id: MGI:7546936
Age: embryonic day 18.5
Image: 5
Specimen Label: WT1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7546867
Assay Type: Western blot
Annotation Date: 2023-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550526
Stage: TS26
Assay Id: MGI:7546936
Age: embryonic day 18.5
Image: 5
Specimen Label: WT2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7546867
Assay Type: Western blot
Annotation Date: 2023-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550526
Stage: TS26
Assay Id: MGI:7546936
Age: embryonic day 18.5
Image: 5
Specimen Label: CKO1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7546867
Assay Type: Western blot
Annotation Date: 2023-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550526
Stage: TS26
Assay Id: MGI:7546936
Age: embryonic day 18.5
Image: 5
Specimen Label: CKO2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7546906
Assay Type: RT-PCR
Annotation Date: 2023-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550526
Stage: TS26
Assay Id: MGI:7546963
Age: embryonic day 18.5
Image: 5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7546906
Assay Type: RT-PCR
Annotation Date: 2023-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550526
Stage: TS26
Assay Id: MGI:7546963
Age: embryonic day 18.5
Image: 5
Specimen Label: CKO
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7616323
Age: embryonic day 13.5
Specimen Label: 13.5 dpc
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7616323
Age: embryonic day 13.5
Specimen Label: 13.5 dpc
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7616323
Age: embryonic day 13.5
Specimen Label: 13.5 dpc
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:7616323
Age: embryonic day 16.5
Specimen Label: 16.5 dpc
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:7616323
Age: embryonic day 16.5
Specimen Label: 16.5 dpc
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:7616323
Age: embryonic day 16.5
Specimen Label: 16.5 dpc
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7616323
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7616323
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7616323
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3679328
Stage: TS28
Assay Id: MGI:7616323
Age: postnatal week 8
Specimen Label: 8 weeks
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3679328
Stage: TS28
Assay Id: MGI:7616323
Age: postnatal week 8
Specimen Label: 8 weeks
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:7615276
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3679328
Stage: TS28
Assay Id: MGI:7616323
Age: postnatal week 8
Specimen Label: 8 weeks
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:3724989
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3516422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421640
Age: embryonic day 14.5
Image: MH1645; Specimen C1769
Specimen Label: MH1645; Specimen C1769
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724989
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1716122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421640
Age: embryonic day 14.5
Image: MH1645; Specimen C1769
Specimen Label: MH1645; Specimen C1769
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724989
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421640
Age: embryonic day 14.5
Image: MH1645; Specimen C1769
Specimen Label: MH1645; Specimen C1769
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724989
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2835226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5540519
Age: embryonic day 17.5
Image: GUDMAP:15222
Specimen Label: GUDMAP:15222
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3724989
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:2835228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5540519
Age: postnatal day 84
Image: GUDMAP:15223
Specimen Label: GUDMAP:15223
Specimen Num: 2
GXD Expression  
Probe: MGI:3724989
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421640
Age: embryonic day 14.5
Image: MH1645; Specimen C1769
Specimen Label: MH1645; Specimen C1769
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724989
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1737322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421640
Age: embryonic day 14.5
Image: MH1645; Specimen C1769
Specimen Label: MH1645; Specimen C1769
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724989
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5540519
Age: embryonic day 17.5
Image: GUDMAP:15222
Specimen Label: GUDMAP:15222
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724989
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5540519
Age: postnatal day 84
Image: GUDMAP:15223
Specimen Label: GUDMAP:15223
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3724989
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3284222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421640
Age: embryonic day 14.5
Image: MH1645; Specimen C1769
Specimen Label: MH1645; Specimen C1769
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724989
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1666522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421640
Age: embryonic day 14.5
Image: MH1645; Specimen C1769
Specimen Label: MH1645; Specimen C1769
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724989
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1619822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421640
Age: embryonic day 14.5
Image: MH1645; Specimen C1769
Specimen Label: MH1645; Specimen C1769
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3724989
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421640
Age: embryonic day 14.5
Image: MH1645; Specimen C1769
Note: Expression was detected in the corpus striatum (lateral ganglionic eminence).
Specimen Label: MH1645; Specimen C1769
Detected: true
Specimen Num: 1