Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
LEM domain-containing protein 2 (LEMD2 or LEM2) is an inner nuclear membrane protein associated with A-type lamins that is involved in nuclear structure organization [, ]. It also plays a role in embryonic development and in the regulation of several signaling pathways [].LEM2 contains an N-terminal LEM domain, two putative transmembrane domains and a MAN1-Src1p C-terminal (MSC) domain, but lacks the Man1-specific C-terminal RNA recognition motif (RRM) []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Tapia O |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Nuclear envelope protein Lem2 is required for mouse development and regulates MAP and AKT kinases. |
Volume: |
10 |
Issue: |
3 |
Pages: |
e0116196 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brachner A |
Year: |
2005 |
Journal: |
J Cell Sci |
Title: |
LEM2 is a novel MAN1-related inner nuclear membrane protein associated with A-type lamins. |
Volume: |
118 |
Issue: |
Pt 24 |
Pages: |
5797-810 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen R |
Year: |
2023 |
Journal: |
Circ Res |
Title: |
Mechanistic Insights of the LEMD2 p.L13R Mutation and Its Role in Cardiomyopathy. |
Volume: |
132 |
Issue: |
2 |
Pages: |
e43-e58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Caravia XM |
Year: |
2022 |
Journal: |
J Clin Invest |
Title: |
Loss of function of the nuclear envelope protein LEMD2 causes DNA damage-dependent cardiomyopathy. |
Volume: |
132 |
Issue: |
22 |
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
511
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
125
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Ulbert S |
Year: |
2006 |
Journal: |
FEBS Lett |
Title: |
The inner nuclear membrane protein Lem2 is critical for normal nuclear envelope morphology. |
Volume: |
580 |
Issue: |
27 |
Pages: |
6435-41 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2677398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-01-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610517 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5705854 |
Age: |
embryonic day 10.5 |
Image: |
6C Heart Lemd2 +/+ |
|
Specimen Label: |
6C Heart Lemd2 +/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2677398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-01-29 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610517 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5705854 |
Age: |
embryonic day 10.5 |
Image: |
6C Heart Lemd2 Gt/Gt |
Note: |
Increased levels of expression compared with wild type embryos. |
Specimen Label: |
6C Heart Lemd2 Gt/Gt |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2677398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-02-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610517 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5706766 |
Age: |
embryonic day 10.5 |
Image: |
6C Heart Lemd2 +/+ |
|
Specimen Label: |
6C Heart Lemd2 +/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2677398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-02-02 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610517 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5706766 |
Age: |
embryonic day 10.5 |
Image: |
6C Heart Lemd2 Gt/Gt |
Note: |
Increased levels of expression compared with wild type embryos. |
Specimen Label: |
6C Heart Lemd2 Gt/Gt |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2677398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-01-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3116917 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5705854 |
Age: |
embryonic day 10.5 |
Image: |
6C Somites Lemd2 +/+ |
|
Specimen Label: |
6C Somites Lemd2 +/+ |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2677398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-01-29 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3116917 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5705854 |
Age: |
embryonic day 10.5 |
Image: |
6C Somites Lemd2 Gt/Gt |
Note: |
Increased levels of expression compared with wild type embryos. |
Specimen Label: |
6C Somites Lemd2 Gt/Gt |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2677398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-02-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3116917 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5706766 |
Age: |
embryonic day 10.5 |
Image: |
6C Somites Lemd2 +/+ |
|
Specimen Label: |
6C Somites Lemd2 +/+ |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2677398 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-02-02 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3116917 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5706766 |
Age: |
embryonic day 10.5 |
Image: |
6C Somites Lemd2 Gt/Gt |
Note: |
Increased levels of expression compared with wild type embryos. |
Specimen Label: |
6C Somites Lemd2 Gt/Gt |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705824 |
Assay Type: |
Northern blot |
Annotation Date: |
2016-01-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603921 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5705851 |
Age: |
embryonic day 13.5 |
Image: |
1 |
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705824 |
Assay Type: |
Northern blot |
Annotation Date: |
2016-01-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603921 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5705851 |
Age: |
embryonic day 13.5 |
Image: |
1 |
|
Specimen Label: |
+/Gt |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5706593 |
Age: |
embryonic day 10.5 |
Image: |
1 |
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5706593 |
Age: |
embryonic day 10.5 |
Image: |
1 |
|
Specimen Label: |
+/Gt |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5706593 |
Age: |
embryonic day 10.5 |
Image: |
1 |
|
Specimen Label: |
Gt/Gt |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5706594 |
Age: |
embryonic day 10.5 |
Image: |
S1 |
|
Specimen Label: |
E10.5 +/+ |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5706594 |
Age: |
embryonic day 10.5 |
Image: |
S1 |
|
Specimen Label: |
E10.5 +/Gt |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5706594 |
Age: |
embryonic day 10.5 |
Image: |
S1 |
|
Specimen Label: |
E10.5 Gt/Gt |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603913 |
|
Stage: |
TS13 |
Assay Id: |
MGI:5706594 |
Age: |
embryonic day 8.5 |
Image: |
S1 |
|
Specimen Label: |
E8.5 +/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603913 |
|
Stage: |
TS13 |
Assay Id: |
MGI:5706594 |
Age: |
embryonic day 8.5 |
Image: |
S1 |
|
Specimen Label: |
E8.5 +/Gt |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603913 |
|
Stage: |
TS13 |
Assay Id: |
MGI:5706594 |
Age: |
embryonic day 8.5 |
Image: |
S1 |
|
Specimen Label: |
E8.5 Gt/Gt |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603921 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5706594 |
Age: |
embryonic day 13.5 |
Image: |
S1 |
|
Specimen Label: |
E13.5 +/+ |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603921 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5706594 |
Age: |
embryonic day 13.5 |
Image: |
S1 |
|
Specimen Label: |
E13.5 +/Gt |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603921 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5706594 |
Age: |
embryonic day 13.5 |
Image: |
S1 |
|
Specimen Label: |
E13.5 Gt/Gt |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3586628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5706596 |
Age: |
postnatal adult |
Image: |
S1 |
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3586628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5706596 |
Age: |
postnatal adult |
Image: |
S1 |
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3586628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5706596 |
Age: |
postnatal adult |
Image: |
S1 |
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3586628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5706596 |
Age: |
postnatal adult |
Image: |
S1 |
|
Specimen Label: |
+/Gt |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3586628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5706596 |
Age: |
postnatal adult |
Image: |
S1 |
|
Specimen Label: |
+/Gt |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3586628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5706596 |
Age: |
postnatal adult |
Image: |
S1 |
|
Specimen Label: |
+/Gt |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5706597 |
Age: |
embryonic day 10.5 |
Image: |
6 |
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5706597 |
Age: |
embryonic day 10.5 |
Image: |
6 |
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5706597 |
Age: |
embryonic day 10.5 |
Image: |
6 |
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5706597 |
Age: |
embryonic day 10.5 |
Image: |
6 |
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5706597 |
Age: |
embryonic day 10.5 |
Image: |
6 |
|
Specimen Label: |
Gt/Gt |
Detected: |
false |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5706597 |
Age: |
embryonic day 10.5 |
Image: |
6 |
|
Specimen Label: |
Gt/Gt |
Detected: |
false |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5706597 |
Age: |
embryonic day 10.5 |
Image: |
6 |
|
Specimen Label: |
Gt/Gt |
Detected: |
false |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5705833 |
Assay Type: |
Western blot |
Annotation Date: |
2016-02-01 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5706597 |
Age: |
embryonic day 10.5 |
Image: |
6 |
|
Specimen Label: |
Gt/Gt |
Detected: |
false |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7331388 |
Assay Type: |
Western blot |
Annotation Date: |
2022-08-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1914628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7331408 |
Age: |
postnatal day 17 |
Image: |
2 |
|
Specimen Label: |
WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7331388 |
Assay Type: |
Western blot |
Annotation Date: |
2022-08-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1914628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7331408 |
Age: |
postnatal day 17 |
Image: |
2 |
|
Specimen Label: |
WT |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7331388 |
Assay Type: |
Western blot |
Annotation Date: |
2022-08-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1914628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7331408 |
Age: |
postnatal day 17 |
Image: |
2 |
|
Specimen Label: |
KO |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7331388 |
Assay Type: |
Western blot |
Annotation Date: |
2022-08-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1914628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7331408 |
Age: |
postnatal day 17 |
Image: |
2 |
|
Specimen Label: |
KO |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2016-01-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610517 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5705852 |
Age: |
embryonic day 10.5 |
Image: |
2C Mesoderm |
|
Specimen Label: |
2C Mesoderm |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2016-01-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
Pattern: |
Widespread |
Stage: |
TS17 |
Assay Id: |
MGI:5705852 |
Age: |
embryonic day 10.5 |
Image: |
2A (left) |
Note: |
Authors report variable levels of expression throughout the embryo. |
Specimen Label: |
2A (left) |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2016-01-29 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:5705852 |
Age: |
embryonic day 10.5 |
Image: |
2A (right) |
Note: |
Slightly higher expression sometimes seen in developing liver, Wolffian duct and certain areas of neurectoderm. |
Specimen Label: |
2A (right) |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2016-01-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603921 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5705852 |
Age: |
embryonic day 13.5 |
Image: |
2B (left) |
|
Specimen Label: |
2B (left) |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2016-01-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603921 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5705852 |
Age: |
embryonic day 13.5 |
Image: |
2B (right) |
|
Specimen Label: |
2B (right) |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2016-01-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684617 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5705852 |
Age: |
embryonic day 10.5 |
Image: |
2A (right) |
|
Specimen Label: |
2A (right) |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2016-01-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684617 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5705852 |
Age: |
embryonic day 10.5 |
Image: |
2C Endoderm |
|
Specimen Label: |
2C Endoderm |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2016-01-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1616417 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5705852 |
Age: |
embryonic day 10.5 |
Image: |
2A (right) |
|
Specimen Label: |
2A (right) |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2016-01-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1616417 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5705852 |
Age: |
embryonic day 10.5 |
Image: |
2C Ectoderm |
|
Specimen Label: |
2C Ectoderm |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2016-01-29 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1657717 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5705852 |
Age: |
embryonic day 10.5 |
Image: |
2A (right) |
|
Specimen Label: |
2A (right) |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huber MD |
Year: |
2009 |
Journal: |
Mol Cell Biol |
Title: |
Overlapping functions of nuclear envelope proteins NET25 (Lem2) and emerin in regulation of extracellular signal-regulated kinase signaling in myoblast differentiation. |
Volume: |
29 |
Issue: |
21 |
Pages: |
5718-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ramirez-Martinez A |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization. |
Volume: |
12 |
Issue: |
1 |
Pages: |
690 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ross JA |
Year: |
2023 |
Journal: |
Cardiovasc Res |
Title: |
Lem2 is essential for cardiac development by maintaining nuclear integrity. |
Volume: |
119 |
Issue: |
11 |
Pages: |
2074-2088 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Mammalian Genetics Unit at Harwell |
Year: |
2004 |
Journal: |
Unpublished |
Title: |
Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Strausberg RL |
Year: |
2002 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |
Volume: |
99 |
Issue: |
26 |
Pages: |
16899-903 |
|
•
•
•
•
•
|
Publication |
First Author: |
NIH Mouse Knockout Inventory |
Year: |
2004 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the NIH Mouse Knockout Inventory |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
Gene Ontology Annotation by the MGI Curatorial Staff |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|