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Search results 1 to 100 out of 2230 for Lep

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Hits by Category

Type Details Score
Gene
3952 | LEP
Type: gene
Organism: human
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Gene
373955 | LEP
Type: gene
Organism: chicken
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Gene
698728 | LEP
Type: gene
Organism: macaque, rhesus
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Gene
100486715 | lep
Type: gene
Organism: frog, western clawed
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Gene
280836 | LEP
Type: gene
Organism: cattle
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Gene
key_79386 | LEP
Type: gene
Organism: horse
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Gene
key_36602 | LEP
Type: gene
Organism: pig, domestic
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Gene
25608 | Lep
Type: gene
Organism: rat
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Gene
403616 | LEP
Type: gene
Organism: dog, domestic
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Gene
449638 | LEP
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:104663 | Lep
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
106728418 | LOC106728418
Type: gene
Organism: human
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Publication
37334306 | J:346939
 
First Author: Roh YJ
Year: 2023
Journal: Front Endocrinol (Lausanne)
Title: Dipterocarpus tuberculatus as a promising anti-obesity treatment in Lep knockout mice.
Volume: 14
Pages: 1167285
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Publication
14752112 | J:89519
First Author: Sekiya M
Year: 2004
Journal: J Biol Chem
Title: Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lep ob/ob mice.
Volume: 279
Issue: 15
Pages: 15084-90
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Publication
19619509 | J:152537
First Author: Sekiya M
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep ob/ob mice.
Volume: 387
Issue: 3
Pages: 511-5
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Publication
12136396 | J:78850
First Author: Chua S Jr
Year: 2002
Journal: Diabetologia
Title: Differential beta cell responses to hyperglycaemia and insulin resistance in two novel congenic strains of diabetes (FVB- Lepr (db)) and obese (DBA- Lep (ob)) mice.
Volume: 45
Issue: 7
Pages: 976-90
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Publication
23690405 | -
First Author: King AM
Year: 2013
Journal: Infect Immun
Title: Leptospiral outer membrane protein LipL41 is not essential for acute leptospirosis but requires a small chaperone protein, lep, for stable expression.
Volume: 81
Issue: 8
Pages: 2768-76
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Protein Domain
IPR031018 | Chaper_lep
Type: Family
Description: Members of this protein family are Lep, an outer membrane lipoprotein LipL41-binding protein that appears to function as a chaperone important to its expression. LipL41 is the third most abundant lipoprotein in the pathogen Leptospira interrogans, but is found in saprophytic Leptospira species as well and is not essential for virulence [].
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Publication
10480614 | J:57075
First Author: Ogawa Y
Year: 1999
Journal: Diabetes
Title: Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin.
Volume: 48
Issue: 9
Pages: 1822-9
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Publication
11158938 | J:68064
First Author: Matsuoka N
Year: 2001
Journal: Am J Physiol Endocrinol Metab
Title: Decreased triglyceride-rich lipoproteins in transgenic skinny mice overexpressing leptin.
Volume: 280
Issue: 2
Pages: E334-9
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Publication
21521746 | J:174906
First Author: Yamada N
Year: 2011
Journal: Endocrinology
Title: Impaired CNS leptin action is implicated in depression associated with obesity.
Volume: 152
Issue: 7
Pages: 2634-43
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Publication
15331557 | J:92072
First Author: Suganami E
Year: 2004
Journal: Diabetes
Title: Leptin stimulates ischemia-induced retinal neovascularization: possible role of vascular endothelial growth factor expressed in retinal endothelial cells.
Volume: 53
Issue: 9
Pages: 2443-8
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Publication
9192391 | J:41295
First Author: Chung WK
Year: 1997
Journal: Obes Res
Title: Polymerase chain reaction-restriction fragment length polymorphisms (PCR-RFLP) and electrophoretic assays for the mouse obese (Lepob) mutation.
Volume: 5
Issue: 3
Pages: 183-5
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Publication
11375346 | J:69591
First Author: Ebihara K
Year: 2001
Journal: Diabetes
Title: Transgenic overexpression of leptin rescues insulin resistance and diabetes in a mouse model of lipoatrophic diabetes.
Volume: 50
Issue: 6
Pages: 1440-8
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Publication
14978271 | J:88655
First Author: Elefteriou F
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Serum leptin level is a regulator of bone mass.
Volume: 101
Issue: 9
Pages: 3258-63
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Publication
10426381 | J:56420
First Author: Masuzaki H
Year: 1999
Journal: Diabetes
Title: Glucose metabolism and insulin sensitivity in transgenic mice overexpressing leptin with lethal yellow agouti mutation: usefulness of leptin for the treatment of obesity-associated diabetes.
Volume: 48
Issue: 8
Pages: 1615-22
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Publication
10791999 | J:62110
First Author: Aizawa-Abe M
Year: 2000
Journal: J Clin Invest
Title: Pathophysiological role of leptin in obesity-related hypertension.
Volume: 105
Issue: 9
Pages: 1243-52
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Publication
16554040 | J:108103
First Author: Okamoto K
Year: 2006
Journal: Brain Res
Title: Sterol regulatory element binding protein (SREBP)-1 expression in brain is affected by age but not by hormones or metabolic changes.
Volume: 1081
Issue: 1
Pages: 19-27
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Publication
29343656 | J:280224
First Author: Roh JI
Year: 2018
Journal: Exp Anim
Title: CRISPR-Cas9-mediated generation of obese and diabetic mouse models.
Volume: 67
Issue: 2
Pages: 229-237
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Publication
22326952 | J:184483
First Author: Wrann CD
Year: 2012
Journal: J Clin Invest
Title: FOSL2 promotes leptin gene expression in human and mouse adipocytes.
Volume: 122
Issue: 3
Pages: 1010-21
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Publication
31085646 | J:276817
First Author: Yook JS
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Leptin in hippocampus mediates benefits of mild exercise by an antioxidant on neurogenesis and memory.
Volume: 116
Issue: 22
Pages: 10988-10993
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Publication
12602920 | J:81933
First Author: Cleary MP
Year: 2003
Journal: Breast Cancer Res Treat
Title: Genetically obese MMTV-TGF-alpha/Lep(ob)Lep(ob) female mice do not develop mammary tumors.
Volume: 77
Issue: 3
Pages: 205-15
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Publication
17932216 | J:141477
First Author: Trevaskis JL
Year: 2008
Journal: Endocrinology
Title: Counterintuitive effects of double-heterozygous null melanocortin-4 receptor and leptin genes on diet-induced obesity and insulin resistance in C57BL/6J mice.
Volume: 149
Issue: 1
Pages: 174-84
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Publication
15994342 | J:101555
First Author: Trevaskis JL
Year: 2005
Journal: Endocrinology
Title: Double leptin and melanocortin-4 receptor gene mutations have an additive effect on fat mass and are associated with reduced effects of leptin on weight loss and food intake.
Volume: 146
Issue: 10
Pages: 4257-65
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Publication
9575960 | J:47168
First Author: Chung WK
Year: 1998
Journal: Am J Physiol
Title: Heterozygosity for Lep(ob) or Lep(rdb) affects body composition and leptin homeostasis in adult mice.
Volume: 274
Issue: 4 Pt 2
Pages: R985-90
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Publication
24752583 | J:216848
First Author: Joost HG
Year: 2014
Journal: Mamm Genome
Title: The genetic basis of obesity-associated type 2 diabetes (diabesity) in polygenic mouse models.
Volume: 25
Issue: 9-10
Pages: 401-12
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Publication
30158241 | J:336830
First Author: Pfuhlmann K
Year: 2018
Journal: Diabetes
Title: Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1.
Volume: 67
Issue: 11
Pages: 2456-2465
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Publication
29519872 | J:262213
First Author: Lo KA
Year: 2018
Journal: Diabetes
Title: Adipocyte Long-Noncoding RNA Transcriptome Analysis of Obese Mice Identified Lnc-Leptin, Which Regulates Leptin.
Volume: 67
Issue: 6
Pages: 1045-1056
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Publication
23963458 | J:316100
First Author: Pathak RR
Year: 2013
Journal: J Biol Chem
Title: Loss of phosphatase and tensin homolog (PTEN) induces leptin-mediated leptin gene expression: feed-forward loop operating in the lung.
Volume: 288
Issue: 41
Pages: 29821-35
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Protein Coding Gene
MGP_CAROLIEiJ_G0028161 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030513 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030486 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0030413 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030496 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0030209 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_104663 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030950 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029611 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030187 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0030331 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0030285 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0030418 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0030321 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030980 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0029325 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029687 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021919 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0029161 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
22275362 | J:183116
First Author: Wei Z
Year: 2012
Journal: J Biol Chem
Title: C1q/TNF-related protein-12 (CTRP12), a novel adipokine that improves insulin sensitivity and glycemic control in mouse models of obesity and diabetes.
Volume: 287
Issue: 13
Pages: 10301-15
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Publication
18375435 | J:138232
First Author: Kebede M
Year: 2008
Journal: Diabetes
Title: Fructose-1,6-bisphosphatase overexpression in pancreatic beta-cells results in reduced insulin secretion: a new mechanism for fat-induced impairment of beta-cell function.
Volume: 57
Issue: 7
Pages: 1887-95
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Publication
20813965 | J:165436
First Author: Cowherd RB
Year: 2010
Journal: Am J Pathol
Title: Adiponectin lowers glucose production by increasing SOGA.
Volume: 177
Issue: 4
Pages: 1936-45
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Publication
8589726 | J:31761
First Author: Chehab FF
Year: 1996
Journal: Nat Genet
Title: Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin.
Volume: 12
Issue: 3
Pages: 318-20
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Publication
25060689 | J:228103
First Author: Cassano S
Year: 2014
Journal: Metabolism
Title: Leptin modulates autophagy in human CD4+CD25- conventional T cells.
Volume: 63
Issue: 10
Pages: 1272-9
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Publication
21151569 | J:167736
First Author: Hong CJ
Year: 2010
Journal: PLoS One
Title: ENU mutagenesis identifies mice with morbid obesity and severe hyperinsulinemia caused by a novel mutation in leptin.
Volume: 5
Issue: 12
Pages: e15333
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Publication
23860123 | J:203187
First Author: Krautkramer KA
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line.
Volume: 305
Issue: 5
Pages: E600-10
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Publication
18369453 | J:134375
First Author: Ferrara CT
Year: 2008
Journal: PLoS Genet
Title: Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling.
Volume: 4
Issue: 3
Pages: e1000034
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Publication
37590136 | J:339645
First Author: Kobiita A
Year: 2023
Journal: Cell Rep
Title: FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress.
Volume: 42
Issue: 8
Pages: 112986
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Publication
10485707 | J:57251
First Author: Shimomura I
Year: 1999
Journal: Nature
Title: Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy.
Volume: 401
Issue: 6748
Pages: 73-6
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Publication
9575979 | J:47074
First Author: Melnyk A
Year: 1998
Journal: Am J Physiol
Title: Temperature-dependent feeding: lack of role for leptin and defect in brown adipose tissue-ablated obese mice.
Volume: 274
Issue: 4 Pt 2
Pages: R1131-5
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Publication
14976145 | J:133073
First Author: Fu L
Year: 2004
Journal: Endocrinology
Title: Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes.
Volume: 145
Issue: 6
Pages: 2594-603
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Publication
23473035 | J:198135
First Author: Deng T
Year: 2013
Journal: Cell Metab
Title: Class II major histocompatibility complex plays an essential role in obesity-induced adipose inflammation.
Volume: 17
Issue: 3
Pages: 411-22
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Publication
24251118 | J:223189
 
First Author: Han C
Year: 2013
Journal: Redox Biol
Title: The role of nitric oxide signaling in food intake; insights from the inner mitochondrial membrane peptidase 2 mutant mice.
Volume: 1
Pages: 498-507
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Publication
26934227 | J:229665
First Author: Ma C
Year: 2016
Journal: Nature
Title: NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis.
Volume: 531
Issue: 7593
Pages: 253-7
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Publication
18941143 | J:149091
First Author: Maglich JM
Year: 2009
Journal: J Lipid Res
Title: The nuclear receptor CAR (NR1I3) regulates serum triglyceride levels under conditions of metabolic stress.
Volume: 50
Issue: 3
Pages: 439-45
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Publication
31506541 | J:285465
First Author: Ãœner AG
Year: 2019
Journal: Sci Rep
Title: Role of POMC and AgRP neuronal activities on glycaemia in mice.
Volume: 9
Issue: 1
Pages: 13068
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Publication
37088120 | J:337235
 
First Author: Guo X
Year: 2023
Journal: Metabolism
Title: Loss of APOO (MIC26) aggravates obesity-related whitening of brown adipose tissue via PPARα-mediated functional interplay between mitochondria and peroxisomes.
Volume: 144
Pages: 155564
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Publication
8349816 | J:14189
First Author: Warden CH
Year: 1993
Journal: J Clin Invest
Title: Coincidence of genetic loci for plasma cholesterol levels and obesity in a multifactorial mouse model.
Volume: 92
Issue: 2
Pages: 773-9
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Publication
16407534 | J:104264
First Author: Alon T
Year: 2006
Journal: J Neurosci
Title: Late-onset leanness in mice with targeted ablation of melanin concentrating hormone neurons.
Volume: 26
Issue: 2
Pages: 389-97
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Publication
24487023 | J:229353
First Author: Zachariah Tom R
Year: 2014
Journal: Diabetes
Title: Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice.
Volume: 63
Issue: 5
Pages: 1560-71
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Publication
9927300 | J:52903
First Author: Ewart-Toland A
Year: 1999
Journal: Endocrinology
Title: Effect of the genetic background on the reproduction of leptin-deficient obese mice.
Volume: 140
Issue: 2
Pages: 732-8
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Publication
37069175 | J:335323
First Author: Li H
Year: 2023
Journal: Nat Commun
Title: The melanocortin action is biased toward protection from weight loss in mice.
Volume: 14
Issue: 1
Pages: 2200
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Publication
21555864 | J:196049
First Author: Scheller EL
Year: 2011
Journal: Cells Tissues Organs
Title: Ectopic expression of Col2.3 and Col3.6 promoters in the brain and association with leptin signaling.
Volume: 194
Issue: 2-4
Pages: 268-73
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Publication
14523051 | J:87976
First Author: Muurling M
Year: 2004
Journal: J Lipid Res
Title: Overexpression of APOC1 in obob mice leads to hepatic steatosis and severe hepatic insulin resistance.
Volume: 45
Issue: 1
Pages: 9-16
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Publication
32289482 | J:341474
 
First Author: Zhao S
Year: 2020
Journal: Mol Metab
Title: Partial leptin deficiency confers resistance to diet-induced obesity in mice.
Volume: 37
Pages: 100995
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Publication
26859333 | J:228862
First Author: Odle AK
Year: 2016
Journal: Endocrinology
Title: Adipocyte Versus Somatotrope Leptin: Regulation of Metabolic Functions in the Mouse.
Volume: 157
Issue: 4
Pages: 1443-56
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Publication
25116704 | J:218720
First Author: Odle AK
Year: 2014
Journal: Endocrinology
Title: Adipocyte versus pituitary leptin in the regulation of pituitary hormones: somatotropes develop normally in the absence of circulating leptin.
Volume: 155
Issue: 11
Pages: 4316-28
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Publication
36496438 | J:332979
First Author: Chen Q
Year: 2022
Journal: Nat Commun
Title: A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis.
Volume: 13
Issue: 1
Pages: 7633
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Publication
12930764 | J:119260
First Author: Lan H
Year: 2003
Journal: Genetics
Title: Dimension reduction for mapping mRNA abundance as quantitative traits.
Volume: 164
Issue: 4
Pages: 1607-14
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Publication
35198900 | J:327757
First Author: McVey JC
Year: 2022
Journal: iScience
Title: NAFLD indirectly impairs antigen-specific CD8+ T cell immunity against liver cancer in mice.
Volume: 25
Issue: 2
Pages: 103847
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Publication
28990936 | J:252600
First Author: Wu C
Year: 2017
Journal: J Clin Invest
Title: Olfactory receptor 544 reduces adiposity by steering fuel preference toward fats.
Volume: 127
Issue: 11
Pages: 4118-4123
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Publication
29925944 | J:265316
First Author: Schwalie PC
Year: 2018
Journal: Nature
Title: A stromal cell population that inhibits adipogenesis in mammalian fat depots.
Volume: 559
Issue: 7712
Pages: 103-108
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Publication
27396327 | J:238680
First Author: Zhang D
Year: 2016
Journal: Cell Rep
Title: miR-182 Regulates Metabolic Homeostasis by Modulating Glucose Utilization in Muscle.
Volume: 16
Issue: 3
Pages: 757-68
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Publication
- | J:189953
   
First Author: Beutler B
Year: 2012
Journal: MGI Direct Data Submission
Title: Direct Data Submission
Volume: v
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Publication
32818435 | J:296618
First Author: Liu L
Year: 2020
Journal: Cell Metab
Title: Triose Kinase Controls the Lipogenic Potential of Fructose and Dietary Tolerance.
Volume: 32
Issue: 4
Pages: 605-618.e7
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Publication
15064421 | J:90242
First Author: Pinto S
Year: 2004
Journal: Science
Title: Rapid rewiring of arcuate nucleus feeding circuits by leptin.
Volume: 304
Issue: 5667
Pages: 110-5
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Publication
35349825 | J:329055
 
First Author: Liu W
Year: 2022
Journal: EBioMedicine
Title: GREM2 is associated with human central obesity and inhibits visceral preadipocyte browning.
Volume: 78
Pages: 103969
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Publication
33657393 | J:303649
First Author: Chen S
Year: 2021
Journal: Cell Metab
Title: The phytochemical hyperforin triggers thermogenesis in adipose tissue via a Dlat-AMPK signaling axis to curb obesity.
Volume: 33
Issue: 3
Pages: 565-580.e7
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Publication
9177786 | J:40727
First Author: Moon BC
Year: 1997
Journal: Genomics
Title: The molecular basis of the obese mutation in ob2J mice.
Volume: 42
Issue: 1
Pages: 152-6
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Publication
- | J:234238
     
First Author: Turer E
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for potbelly2
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Publication
14824537 | J:13066
First Author: INGALLS AM
Year: 1950
Journal: J Hered
Title: Obese, a new mutation in the house mouse.
Volume: 41
Issue: 12
Pages: 317-8
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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