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Search results 1 to 100 out of 3210 for Lepr

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Hits by Strain

Type Details Score
Gene
3953 | LEPR
Type: gene
Organism: human
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Gene
724071 | lepr
Type: gene
Organism: frog, western clawed
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Gene
497205 | LEPR
Type: gene
Organism: cattle
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Gene
key_80648 | LEPR
Type: gene
Organism: pig, domestic
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Gene
24536 | Lepr
Type: gene
Organism: rat
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Gene
450207 | LEPR
Type: gene
Organism: dog, domestic
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Gene
456919 | LEPR
Type: gene
Organism: chimpanzee
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Gene
374223 | LEPR
Type: gene
Organism: chicken
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Gene
567241 | lepr
Type: gene
Organism: zebrafish
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Gene
574126 | LEPR
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:104993 | Lepr
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q8BTS6
Organism: Mus musculus/domesticus
Length: 79  
Fragment?: true
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Publication
- | J:232775
     
First Author: Lo C
Year: 2016
Journal: MGI Direct Data Submission
Title: A new spontaneous mutation in Lepr
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Publication
34433027 | J:316755
First Author: Siemian JN
Year: 2021
Journal: Cell Rep
Title: Lateral hypothalamic LEPR neurons drive appetitive but not consummatory behaviors.
Volume: 36
Issue: 8
Pages: 109615
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Publication
26529315 | J:244001
First Author: Tu X
Year: 2015
Journal: PLoS One
Title: The Influence of LepR Tyrosine Site Mutations on Mouse Ovary Development and Related Gene Expression Changes.
Volume: 10
Issue: 11
Pages: e0141800
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Publication
15870101 | J:100922
First Author: McMinn JE
Year: 2005
Journal: Am J Physiol Endocrinol Metab
Title: Neuronal deletion of Lepr elicits diabesity in mice without affecting cold tolerance or fertility.
Volume: 289
Issue: 3
Pages: E403-11
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Publication
- | J:159354
     
First Author: Huang H
Year: 2010
Journal: MGI Direct Data Submission
Title: Odd is an allele of Lepr and causes excessive body weight
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Publication
30376348 | J:273890
First Author: Borges BC
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: Insulin signaling in LepR cells modulates fat and glucose homeostasis independent of leptin.
Volume: 316
Issue: 1
Pages: E121-E134
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Publication
27048248 | J:234803
First Author: Do OH
Year: 2016
Journal: Diabetologia
Title: Changes in beta cell function occur in prediabetes and early disease in the Lepr (db) mouse model of diabetes.
Volume: 59
Issue: 6
Pages: 1222-30
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Publication
31317664 | J:298467
First Author: Mao Z
Year: 2019
Journal: IUBMB Life
Title: MicroRNA-155 inhibition up-regulates LEPR to inhibit osteoclast activation and bone resorption via activation of AMPK in alendronate-treated osteoporotic mice.
Volume: 71
Issue: 12
Pages: 1916-1928
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Publication
- | J:133632
     
First Author: Georgel P
Year: 2008
Journal: MGI Direct Data Submission
Title: Business class is an allele of Lepr (leptin receptor) associated with massive obesity and diabetes
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Publication
- | J:133633
     
First Author: Xiao N
Year: 2008
Journal: MGI Direct Data Submission
Title: Cherub is an allele of lepr (leptin receptor) associated with massive obesity and infertility
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GXD Expression
GXD Expression
     
Probe: MGI:6176374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190702
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Lepr
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6176374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190702
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Lepr
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6176374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190702
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Lepr
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:6176374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190702
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Lepr
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6176374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190702
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Lepr
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6176374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190702
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Lepr
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6176374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190702
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Lepr
Detected: true
Specimen Num: 6
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Publication
12136396 | J:78850
First Author: Chua S Jr
Year: 2002
Journal: Diabetologia
Title: Differential beta cell responses to hyperglycaemia and insulin resistance in two novel congenic strains of diabetes (FVB- Lepr (db)) and obese (DBA- Lep (ob)) mice.
Volume: 45
Issue: 7
Pages: 976-90
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Publication
26168341 | J:226929
First Author: Allensworth-James ML
Year: 2015
Journal: Endocrinology
Title: Sex Differences in Somatotrope Dependency on Leptin Receptors in Young Mice: Ablation of LEPR Causes Severe Growth Hormone Deficiency and Abdominal Obesity in Males.
Volume: 156
Issue: 9
Pages: 3253-64
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Publication
27101301 | J:343928
First Author: Allen SJ
Year: 2016
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Leptin receptor null mice with reexpression of LepR in GnRHR expressing cells display elevated FSH levels but remain in a prepubertal state.
Volume: 310
Issue: 11
Pages: R1258-66
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Protein
Q640Q2
Organism: Mus musculus/domesticus
Length: 818  
Fragment?: false
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Publication
20851886 | J:167342
First Author: Kapur S
Year: 2010
Journal: J Biol Chem
Title: Leptin receptor (Lepr) is a negative modulator of bone mechanosensitivity and genetic variations in Lepr may contribute to the differential osteogenic response to mechanical stimulation in the C57BL/6J and C3H/HeJ pair of mouse strains.
Volume: 285
Issue: 48
Pages: 37607-18
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Publication
28580288 | J:273902
First Author: D'souza AM
Year: 2017
Journal: Mol Metab
Title: Restoration of Lepr in β cells of Lepr null mice does not prevent hyperinsulinemia and hyperglycemia.
Volume: 6
Issue: 6
Pages: 585-593
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Publication
561759 | J:31044
First Author: McAdam KP
Year: 1977
Journal: Int J Lepr Other Mycobact Dis
Title: Secondary amyloidosis and the serum amyloid precursor in leprosy: geographical variation and association with leukocytosis.
Volume: 45
Issue: 2
Pages: 150-7
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Publication
8642224 | J:31717
First Author: Birdi TJ
Year: 1995
Journal: Int J Lepr Other Mycobact Dis
Title: Differences in M. leprae-induced nerve damage in Swiss white and C57BL/6 mice.
Volume: 63
Issue: 4
Pages: 573-4
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Publication
9207757 | J:42691
First Author: Yogi Y
Year: 1997
Journal: Int J Lepr Other Mycobact Dis
Title: Cytokine gene expression in the foot pad and spleen of BALB/cAJcl mice infected with M. leprae.
Volume: 65
Issue: 1
Pages: 80-9
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Publication
1802942 | J:859
First Author: Tanaka M
Year: 1991
Journal: Int J Lepr Other Mycobact Dis
Title: Effects of cyclosporin A on bacterial growth and immunological responsiveness in BALB/c mice infected with Mycobacterium leprae.
Volume: 59
Issue: 4
Pages: 598-604
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Publication
- | J:31691
First Author: Falconer DS
Year: 1959
Journal: J Hered
Title: Adipose, a new inherited obesity of the mouse.
Volume: 50
Issue: 6
Pages: 290-292
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Publication
- | J:27525
 
First Author: Hummel KP
Year: 1973
Journal: Mouse News Lett
Title: Allele test
Volume: 48
Pages: 34
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Publication
9845674 | J:53637
First Author: Igel M
Year: 1998
Journal: J Mol Endocrinol
Title: Hyperleptinemia and leptin receptor variant Asp600Asn in the obese, hyperinsulinemic KK mouse strain.
Volume: 21
Issue: 3
Pages: 337-45
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Publication
6993269 | J:6337
First Author: Leiter EH
Year: 1980
Journal: Diabetologia
Title: A new mutation (db3J) at the diabetes locus in strain 129/J mice. I. Physiological and histological characterization.
Volume: 19
Issue: 1
Pages: 58-65
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Publication
32248977 | J:311411
First Author: Pollock KE
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Morphology and gene expression in mouse placentas lacking leptin receptors.
Volume: 528
Issue: 2
Pages: 336-342
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Publication
9166593 | J:40658
First Author: Lee G
Year: 1997
Journal: Mamm Genome
Title: Leptin receptor mutations in 129 db3J/db3J mice and NIH facp/facp rats.
Volume: 8
Issue: 6
Pages: 445-7
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Publication
- | J:267679
     
First Author: Keef J
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for fluffy.
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Publication
- | J:272857
     
First Author: Zhang Z
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for gordo.
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Publication
- | J:274729
     
First Author: Zhang Z
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for donner.
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Publication
32047110 | J:287448
First Author: Iqbal J
Year: 2020
Journal: J Biol Chem
Title: Leptin-mediated differential regulation of microsomal triglyceride transfer protein in the intestine and liver affects plasma lipids.
Volume: 295
Issue: 13
Pages: 4101-4113
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Publication
16484328 | J:129660
First Author: Luo N
Year: 2006
Journal: Endocrinology
Title: Allelic variation on chromosome 5 controls beta-cell mass expansion during hyperglycemia in leptin receptor-deficient diabetes mice.
Volume: 147
Issue: 5
Pages: 2287-95
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Publication
9545355 | J:47037
First Author: Li C
Year: 1998
Journal: J Biol Chem
Title: Absence of soluble leptin receptor in plasma from dbPas/dbPas and other db/db mice.
Volume: 273
Issue: 16
Pages: 10078-82
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Publication
26468261 | J:237589
First Author: Harris RB
Year: 2015
Journal: Am J Physiol Regul Integr Comp Physiol
Title: In vivo evidence for unidentified leptin-induced circulating factors that control white fat mass.
Volume: 309
Issue: 12
Pages: R1499-511
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Publication
- | J:124155
     
First Author: Naggert JK
Year: 2007
Journal: MGI Direct Data Submission
Title: A remutation of Lepr
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Publication
11980179 | J:76711
First Author: Camand O
Year: 2002
Journal: C R Biol
Title: Embryonic expression of the leptin receptor gene in mesoderm-derived tissues.
Volume: 325
Issue: 2
Pages: 77-87
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Publication
8584938 | J:31419
First Author: Chua SC Jr
Year: 1996
Journal: Science
Title: Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor.
Volume: 271
Issue: 5251
Pages: 994-6
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Publication
3044893 | J:109940
First Author: Yoon JW
Year: 1988
Journal: Diabetes
Title: Genetic control of organ-reactive autoantibody production in mice by obesity (ob) diabetes (db) genes.
Volume: 37
Issue: 9
Pages: 1287-93
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Publication
10666131 | J:60363
First Author: Brown JA
Year: 2000
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Spontaneous mutation in the db gene results in obesity and diabetes in CD-1 outbred mice.
Volume: 278
Issue: 2
Pages: R320-30
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Publication
36423694 | J:332416
 
First Author: Milbank E
Year: 2023
Journal: Metabolism
Title: Small extracellular vesicle targeting of hypothalamic AMPKα1 promotes weight loss in leptin receptor deficient mice.
Volume: 139
Pages: 155350
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Publication
34129812 | J:325183
First Author: Butiaeva LI
Year: 2021
Journal: Cell Metab
Title: Leptin receptor-expressing pericytes mediate access of hypothalamic feeding centers to circulating leptin.
Volume: 33
Issue: 7
Pages: 1433-1448.e5
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Publication
18997673 | J:173593
First Author: Stratigopoulos G
Year: 2009
Journal: Obesity (Silver Spring)
Title: Functional consequences of the human leptin receptor (LEPR) Q223R transversion.
Volume: 17
Issue: 1
Pages: 126-35
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Publication
10854702 | J:62804
First Author: Horev G
Year: 2000
Journal: Mol Cell Endocrinol
Title: Molecular cloning and properties of the chicken leptin-receptor (CLEPR) gene.
Volume: 162
Issue: 1-2
Pages: 95-106
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Publication
35857512 | J:328324
First Author: Guo Z
Year: 2022
Journal: Sci Adv
Title: Leptin receptor signaling sustains metabolic fitness of alveolar macrophages to attenuate pulmonary inflammation.
Volume: 8
Issue: 28
Pages: eabo3064
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Publication
38091996 | J:349260
First Author: Haberman ER
Year: 2024
Journal: Immunity
Title: Immunomodulatory leptin receptor(+) sympathetic perineurial barrier cells protect against obesity by facilitating brown adipose tissue thermogenesis.
Volume: 57
Issue: 1
Pages: 141-152.e5
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Publication
25176149 | J:215557
First Author: Dodd GT
Year: 2014
Journal: Cell Metab
Title: The thermogenic effect of leptin is dependent on a distinct population of prolactin-releasing peptide neurons in the dorsomedial hypothalamus.
Volume: 20
Issue: 4
Pages: 639-49
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Publication
34341568 | J:348113
First Author: Duquenne M
Year: 2021
Journal: Nat Metab
Title: Leptin brain entry via a tanycytic LepR-EGFR shuttle controls lipid metabolism and pancreas function.
Volume: 3
Issue: 8
Pages: 1071-1090
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Publication
32251290 | J:289128
First Author: Jiang L
Year: 2020
Journal: Nat Commun
Title: Leptin receptor-expressing neuron Sh2b1 supports sympathetic nervous system and protects against obesity and metabolic disease.
Volume: 11
Issue: 1
Pages: 1517
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Publication
38147550 | J:353726
First Author: Hu H
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: ANGPTL4 binds to the leptin receptor to regulate ectopic bone formation.
Volume: 121
Issue: 1
Pages: e2310685120
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Publication
30694175 | J:275102
   
First Author: Ramos-Lobo AM
Year: 2019
Journal: Elife
Title: Long-term consequences of the absence of leptin signaling in early life.
Volume: 8
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Publication
27166944 | J:235371
First Author: Djogo T
Year: 2016
Journal: Cell Metab
Title: Adult NG2-Glia Are Required for Median Eminence-Mediated Leptin Sensing and Body Weight Control.
Volume: 23
Issue: 5
Pages: 797-810
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Publication
29761783 | J:264790
   
First Author: Yu S
Year: 2018
Journal: Elife
Title: Preoptic leptin signaling modulates energy balance independent of body temperature regulation.
Volume: 7
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Publication
24567904 | J:221293
First Author: Sadagurski M
Year: 2014
Journal: Mol Metab
Title: Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasis.
Volume: 3
Issue: 1
Pages: 55-63
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Publication
37433299 | J:341053
First Author: Breit SN
Year: 2023
Journal: Cell Metab
Title: GDF15 enhances body weight and adiposity reduction in obese mice by leveraging the leptin pathway.
Volume: 35
Issue: 8
Pages: 1341-1355.e3
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Publication
27053299 | J:235077
First Author: Yue R
Year: 2016
Journal: Cell Stem Cell
Title: Leptin Receptor Promotes Adipogenesis and Reduces Osteogenesis by Regulating Mesenchymal Stromal Cells in Adult Bone Marrow.
Volume: 18
Issue: 6
Pages: 782-96
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Publication
34018926 | J:357295
   
First Author: Affinati AH
Year: 2021
Journal: Elife
Title: Cross-species analysis defines the conservation of anatomically segregated VMH neuron populations.
Volume: 10
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Publication
29343656 | J:280224
First Author: Roh JI
Year: 2018
Journal: Exp Anim
Title: CRISPR-Cas9-mediated generation of obese and diabetic mouse models.
Volume: 67
Issue: 2
Pages: 229-237
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Publication
30352426 | J:270992
First Author: Li CJ
Year: 2018
Journal: J Clin Invest
Title: Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging.
Volume: 128
Issue: 12
Pages: 5251-5266
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Publication
38569472 | J:347397
First Author: Guan D
Year: 2024
Journal: Cell Metab
Title: Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss.
Volume: 36
Issue: 4
Pages: 857-876.e10
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Publication
37116488 | J:341036
First Author: Takahashi K
Year: 2023
Journal: Cell Rep
Title: Inter-organ insulin-leptin signal crosstalk from the liver enhances survival during food shortages.
Volume: 42
Issue: 5
Pages: 112415
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Publication
29528284 | J:269652
   
First Author: Caron A
Year: 2018
Journal: Elife
Title: POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels.
Volume: 7
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Publication
30133304 | J:266061
First Author: Duffy S
Year: 2018
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Rodent models of leptin receptor deficiency are less sensitive to amylin.
Volume: 315
Issue: 4
Pages: R856-R865
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Publication
30824713 | J:276723
First Author: Pereira S
Year: 2019
Journal: Sci Rep
Title: Metabolic effects of leptin receptor knockdown or reconstitution in adipose tissues.
Volume: 9
Issue: 1
Pages: 3307
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Publication
34276560 | J:321438
 
First Author: de Vrind VAJ
Year: 2021
Journal: Front Endocrinol (Lausanne)
Title: Leptin Receptor Expressing Neurons in the Substantia Nigra Regulate Locomotion, and in The Ventral Tegmental Area Motivation and Feeding.
Volume: 12
Pages: 680494
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Publication
31314542 | J:279262
First Author: Senn SS
Year: 2019
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Unsilencing of native LepRs in hypothalamic SF1 neurons does not rescue obese phenotype in LepR-deficient mice.
Volume: 317
Issue: 3
Pages: R451-R460
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Publication
9344648 | J:44004
First Author: Chua SC Jr
Year: 1997
Journal: Genomics
Title: Fine structure of the murine leptin receptor gene: splice site suppression is required to form two alternatively spliced transcripts.
Volume: 45
Issue: 2
Pages: 264-70
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Publication
24055508 | J:316603
First Author: Ikeda A
Year: 2014
Journal: Gastroenterology
Title: Leptin receptor somatic mutations are frequent in HCV-infected cirrhotic liver and associated with hepatocellular carcinoma.
Volume: 146
Issue: 1
Pages: 222-32.e35
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Publication
34390703 | J:313303
 
First Author: Berger C
Year: 2021
Journal: J Lipid Res
Title: A novel compound heterozygous leptin receptor mutation causes more severe obesity than in Leprdb/db mice.
Volume: 62
Pages: 100105
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Publication
24166957 | J:206187
First Author: Madan R
Year: 2014
Journal: Infect Immun
Title: Role of leptin-mediated colonic inflammation in defense against Clostridium difficile colitis.
Volume: 82
Issue: 1
Pages: 341-9
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Publication
16284652 | J:104582
First Author: de Luca C
Year: 2005
Journal: J Clin Invest
Title: Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes.
Volume: 115
Issue: 12
Pages: 3484-93
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Publication
18042135 | J:150180
First Author: Wright DE
Year: 2007
Journal: J Peripher Nerv Syst
Title: Selective changes in nocifensive behavior despite normal cutaneous axon innervation in leptin receptor-null mutant (db/db) mice.
Volume: 12
Issue: 4
Pages: 250-61
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Publication
37850093 | J:347847
 
First Author: Majimbi M
Year: 2023
Journal: Front Endocrinol (Lausanne)
Title: In vivo retinal imaging is associated with cognitive decline, blood-brain barrier disruption and neuroinflammation in type 2 diabetic mice.
Volume: 14
Pages: 1224418
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Publication
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