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Search results 1 to 100 out of 3076 for Lepr

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0.038s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: pig, domestic
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 79  
Fragment?: true
Publication      
First Author: Lo C
Year: 2016
Journal: MGI Direct Data Submission
Title: A new spontaneous mutation in Lepr
Publication
First Author: Siemian JN
Year: 2021
Journal: Cell Rep
Title: Lateral hypothalamic LEPR neurons drive appetitive but not consummatory behaviors.
Volume: 36
Issue: 8
Pages: 109615
Publication
First Author: McMinn JE
Year: 2005
Journal: Am J Physiol Endocrinol Metab
Title: Neuronal deletion of Lepr elicits diabesity in mice without affecting cold tolerance or fertility.
Volume: 289
Issue: 3
Pages: E403-11
Publication
First Author: Tu X
Year: 2015
Journal: PLoS One
Title: The Influence of LepR Tyrosine Site Mutations on Mouse Ovary Development and Related Gene Expression Changes.
Volume: 10
Issue: 11
Pages: e0141800
Publication
First Author: Borges BC
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: Insulin signaling in LepR cells modulates fat and glucose homeostasis independent of leptin.
Volume: 316
Issue: 1
Pages: E121-E134
Publication      
First Author: Huang H
Year: 2010
Journal: MGI Direct Data Submission
Title: Odd is an allele of Lepr and causes excessive body weight
Publication
First Author: Do OH
Year: 2016
Journal: Diabetologia
Title: Changes in beta cell function occur in prediabetes and early disease in the Lepr (db) mouse model of diabetes.
Volume: 59
Issue: 6
Pages: 1222-30
Publication
First Author: Mao Z
Year: 2019
Journal: IUBMB Life
Title: MicroRNA-155 inhibition up-regulates LEPR to inhibit osteoclast activation and bone resorption via activation of AMPK in alendronate-treated osteoporotic mice.
Volume: 71
Issue: 12
Pages: 1916-1928
Publication      
First Author: Xiao N
Year: 2008
Journal: MGI Direct Data Submission
Title: Cherub is an allele of lepr (leptin receptor) associated with massive obesity and infertility
Publication      
First Author: Georgel P
Year: 2008
Journal: MGI Direct Data Submission
Title: Business class is an allele of Lepr (leptin receptor) associated with massive obesity and diabetes
GXD Expression      
Probe: MGI:6176374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190702
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Lepr
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:6176374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190702
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Lepr
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6176374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190702
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Lepr
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6176374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190702
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Lepr
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6176374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190702
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Lepr
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6176374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190702
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Lepr
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6176374
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190702
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Lepr
Detected: true
Specimen Num: 7
Publication
First Author: Chua S Jr
Year: 2002
Journal: Diabetologia
Title: Differential beta cell responses to hyperglycaemia and insulin resistance in two novel congenic strains of diabetes (FVB- Lepr (db)) and obese (DBA- Lep (ob)) mice.
Volume: 45
Issue: 7
Pages: 976-90
Publication
First Author: Allensworth-James ML
Year: 2015
Journal: Endocrinology
Title: Sex Differences in Somatotrope Dependency on Leptin Receptors in Young Mice: Ablation of LEPR Causes Severe Growth Hormone Deficiency and Abdominal Obesity in Males.
Volume: 156
Issue: 9
Pages: 3253-64
Publication
First Author: Allen SJ
Year: 2016
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Leptin receptor null mice with reexpression of LepR in GnRHR expressing cells display elevated FSH levels but remain in a prepubertal state.
Volume: 310
Issue: 11
Pages: R1258-66
Protein
Organism: Mus musculus/domesticus
Length: 818  
Fragment?: false
Publication
First Author: Kapur S
Year: 2010
Journal: J Biol Chem
Title: Leptin receptor (Lepr) is a negative modulator of bone mechanosensitivity and genetic variations in Lepr may contribute to the differential osteogenic response to mechanical stimulation in the C57BL/6J and C3H/HeJ pair of mouse strains.
Volume: 285
Issue: 48
Pages: 37607-18
Publication
First Author: D'souza AM
Year: 2017
Journal: Mol Metab
Title: Restoration of Lepr in β cells of Lepr null mice does not prevent hyperinsulinemia and hyperglycemia.
Volume: 6
Issue: 6
Pages: 585-593
Publication
First Author: McAdam KP
Year: 1977
Journal: Int J Lepr Other Mycobact Dis
Title: Secondary amyloidosis and the serum amyloid precursor in leprosy: geographical variation and association with leukocytosis.
Volume: 45
Issue: 2
Pages: 150-7
Publication
First Author: Birdi TJ
Year: 1995
Journal: Int J Lepr Other Mycobact Dis
Title: Differences in M. leprae-induced nerve damage in Swiss white and C57BL/6 mice.
Volume: 63
Issue: 4
Pages: 573-4
Publication
First Author: Yogi Y
Year: 1997
Journal: Int J Lepr Other Mycobact Dis
Title: Cytokine gene expression in the foot pad and spleen of BALB/cAJcl mice infected with M. leprae.
Volume: 65
Issue: 1
Pages: 80-9
Publication
First Author: Tanaka M
Year: 1991
Journal: Int J Lepr Other Mycobact Dis
Title: Effects of cyclosporin A on bacterial growth and immunological responsiveness in BALB/c mice infected with Mycobacterium leprae.
Volume: 59
Issue: 4
Pages: 598-604
Publication
First Author: Falconer DS
Year: 1959
Journal: J Hered
Title: Adipose, a new inherited obesity of the mouse.
Volume: 50
Issue: 6
Pages: 290-292
Publication  
First Author: Hummel KP
Year: 1973
Journal: Mouse News Lett
Title: Allele test
Volume: 48
Pages: 34
Publication
First Author: Igel M
Year: 1998
Journal: J Mol Endocrinol
Title: Hyperleptinemia and leptin receptor variant Asp600Asn in the obese, hyperinsulinemic KK mouse strain.
Volume: 21
Issue: 3
Pages: 337-45
Publication
First Author: Leiter EH
Year: 1980
Journal: Diabetologia
Title: A new mutation (db3J) at the diabetes locus in strain 129/J mice. I. Physiological and histological characterization.
Volume: 19
Issue: 1
Pages: 58-65
Publication
First Author: Pollock KE
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Morphology and gene expression in mouse placentas lacking leptin receptors.
Volume: 528
Issue: 2
Pages: 336-342
Publication
First Author: Lee G
Year: 1997
Journal: Mamm Genome
Title: Leptin receptor mutations in 129 db3J/db3J mice and NIH facp/facp rats.
Volume: 8
Issue: 6
Pages: 445-7
Publication      
First Author: Zhang Z
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for donner.
Publication      
First Author: Keef J
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for fluffy.
Publication      
First Author: Zhang Z
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for gordo.
Publication
First Author: Iqbal J
Year: 2020
Journal: J Biol Chem
Title: Leptin-mediated differential regulation of microsomal triglyceride transfer protein in the intestine and liver affects plasma lipids.
Volume: 295
Issue: 13
Pages: 4101-4113
Publication
First Author: Li C
Year: 1998
Journal: J Biol Chem
Title: Absence of soluble leptin receptor in plasma from dbPas/dbPas and other db/db mice.
Volume: 273
Issue: 16
Pages: 10078-82
Publication
First Author: Luo N
Year: 2006
Journal: Endocrinology
Title: Allelic variation on chromosome 5 controls beta-cell mass expansion during hyperglycemia in leptin receptor-deficient diabetes mice.
Volume: 147
Issue: 5
Pages: 2287-95
Publication
First Author: Harris RB
Year: 2015
Journal: Am J Physiol Regul Integr Comp Physiol
Title: In vivo evidence for unidentified leptin-induced circulating factors that control white fat mass.
Volume: 309
Issue: 12
Pages: R1499-511
Publication
First Author: Camand O
Year: 2002
Journal: C R Biol
Title: Embryonic expression of the leptin receptor gene in mesoderm-derived tissues.
Volume: 325
Issue: 2
Pages: 77-87
Publication      
First Author: Naggert JK
Year: 2007
Journal: MGI Direct Data Submission
Title: A remutation of Lepr
Publication
First Author: Chua SC Jr
Year: 1996
Journal: Science
Title: Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor.
Volume: 271
Issue: 5251
Pages: 994-6
Publication
First Author: Yoon JW
Year: 1988
Journal: Diabetes
Title: Genetic control of organ-reactive autoantibody production in mice by obesity (ob) diabetes (db) genes.
Volume: 37
Issue: 9
Pages: 1287-93
Publication
First Author: Butiaeva LI
Year: 2021
Journal: Cell Metab
Title: Leptin receptor-expressing pericytes mediate access of hypothalamic feeding centers to circulating leptin.
Volume: 33
Issue: 7
Pages: 1433-1448.e5
Publication
First Author: Stratigopoulos G
Year: 2009
Journal: Obesity (Silver Spring)
Title: Functional consequences of the human leptin receptor (LEPR) Q223R transversion.
Volume: 17
Issue: 1
Pages: 126-35
Publication
First Author: Brown JA
Year: 2000
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Spontaneous mutation in the db gene results in obesity and diabetes in CD-1 outbred mice.
Volume: 278
Issue: 2
Pages: R320-30
Publication  
First Author: Milbank E
Year: 2023
Journal: Metabolism
Title: Small extracellular vesicle targeting of hypothalamic AMPKα1 promotes weight loss in leptin receptor deficient mice.
Volume: 139
Pages: 155350
Publication
First Author: Horev G
Year: 2000
Journal: Mol Cell Endocrinol
Title: Molecular cloning and properties of the chicken leptin-receptor (CLEPR) gene.
Volume: 162
Issue: 1-2
Pages: 95-106
Publication
First Author: Guo Z
Year: 2022
Journal: Sci Adv
Title: Leptin receptor signaling sustains metabolic fitness of alveolar macrophages to attenuate pulmonary inflammation.
Volume: 8
Issue: 28
Pages: eabo3064
Publication
First Author: Dodd GT
Year: 2014
Journal: Cell Metab
Title: The thermogenic effect of leptin is dependent on a distinct population of prolactin-releasing peptide neurons in the dorsomedial hypothalamus.
Volume: 20
Issue: 4
Pages: 639-49
Publication
First Author: Jiang L
Year: 2020
Journal: Nat Commun
Title: Leptin receptor-expressing neuron Sh2b1 supports sympathetic nervous system and protects against obesity and metabolic disease.
Volume: 11
Issue: 1
Pages: 1517
Publication
First Author: Yue R
Year: 2016
Journal: Cell Stem Cell
Title: Leptin Receptor Promotes Adipogenesis and Reduces Osteogenesis by Regulating Mesenchymal Stromal Cells in Adult Bone Marrow.
Volume: 18
Issue: 6
Pages: 782-96
Publication
First Author: Breit SN
Year: 2023
Journal: Cell Metab
Title: GDF15 enhances body weight and adiposity reduction in obese mice by leveraging the leptin pathway.
Volume: 35
Issue: 8
Pages: 1341-1355.e3
Publication
First Author: Roh JI
Year: 2018
Journal: Exp Anim
Title: CRISPR-Cas9-mediated generation of obese and diabetic mouse models.
Volume: 67
Issue: 2
Pages: 229-237
Publication    
First Author: Ramos-Lobo AM
Year: 2019
Journal: Elife
Title: Long-term consequences of the absence of leptin signaling in early life.
Volume: 8
Publication    
First Author: Yu S
Year: 2018
Journal: Elife
Title: Preoptic leptin signaling modulates energy balance independent of body temperature regulation.
Volume: 7
Publication
First Author: Li CJ
Year: 2018
Journal: J Clin Invest
Title: Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging.
Volume: 128
Issue: 12
Pages: 5251-5266
Publication
First Author: Sadagurski M
Year: 2014
Journal: Mol Metab
Title: Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasis.
Volume: 3
Issue: 1
Pages: 55-63
Publication
First Author: Djogo T
Year: 2016
Journal: Cell Metab
Title: Adult NG2-Glia Are Required for Median Eminence-Mediated Leptin Sensing and Body Weight Control.
Volume: 23
Issue: 5
Pages: 797-810
Publication    
First Author: Caron A
Year: 2018
Journal: Elife
Title: POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels.
Volume: 7
Publication
First Author: Takahashi K
Year: 2023
Journal: Cell Rep
Title: Inter-organ insulin-leptin signal crosstalk from the liver enhances survival during food shortages.
Volume: 42
Issue: 5
Pages: 112415
Publication
First Author: Chua SC Jr
Year: 1997
Journal: Genomics
Title: Fine structure of the murine leptin receptor gene: splice site suppression is required to form two alternatively spliced transcripts.
Volume: 45
Issue: 2
Pages: 264-70
Publication
First Author: Chua SC Jr
Year: 2004
Journal: Am J Physiol Endocrinol Metab
Title: Transgenic complementation of leptin receptor deficiency. II. Increased leptin receptor transgene dose effects on obesity/diabetes and fertility/lactation in lepr-db/db mice.
Volume: 286
Issue: 3
Pages: E384-92
Publication
First Author: de Luca C
Year: 2005
Journal: J Clin Invest
Title: Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes.
Volume: 115
Issue: 12
Pages: 3484-93
Publication
First Author: Pereira S
Year: 2019
Journal: Sci Rep
Title: Metabolic effects of leptin receptor knockdown or reconstitution in adipose tissues.
Volume: 9
Issue: 1
Pages: 3307
Publication
First Author: Childs GV
Year: 2011
Journal: Endocrinology
Title: The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity.
Volume: 152
Issue: 1
Pages: 69-81
Publication
First Author: Oka H
Year: 2023
Journal: Sci Rep
Title: Subset of the periodontal ligament expressed leptin receptor contributes to part of hard tissue-forming cells.
Volume: 13
Issue: 1
Pages: 3442
Publication
First Author: Kakava-Georgiadou N
Year: 2022
Journal: Sci Rep
Title: Molecular profile and response to energy deficit of leptin-receptor neurons in the lateral hypothalamus.
Volume: 12
Issue: 1
Pages: 13374
Publication  
First Author: de Vrind VAJ
Year: 2021
Journal: Front Endocrinol (Lausanne)
Title: Leptin Receptor Expressing Neurons in the Substantia Nigra Regulate Locomotion, and in The Ventral Tegmental Area Motivation and Feeding.
Volume: 12
Pages: 680494
Publication
First Author: Senn SS
Year: 2019
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Unsilencing of native LepRs in hypothalamic SF1 neurons does not rescue obese phenotype in LepR-deficient mice.
Volume: 317
Issue: 3
Pages: R451-R460
Publication  
First Author: Berger C
Year: 2021
Journal: J Lipid Res
Title: A novel compound heterozygous leptin receptor mutation causes more severe obesity than in Leprdb/db mice.
Volume: 62
Pages: 100105
Publication
First Author: Kim JH
Year: 2003
Journal: J Nutr
Title: New leptin receptor mutations in mice: Lepr(db-rtnd), Lepr(db-dmpg) and Lepr(db-rlpy).
Volume: 133
Issue: 5
Pages: 1265-71
Publication
First Author: Bingham NC
Year: 2008
Journal: Endocrinology
Title: Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome.
Volume: 149
Issue: 5
Pages: 2138-48
Publication
First Author: Duggal P
Year: 2011
Journal: J Clin Invest
Title: A mutation in the leptin receptor is associated with Entamoeba histolytica infection in children.
Volume: 121
Issue: 3
Pages: 1191-8
Publication
First Author: Shi H
Year: 2010
Journal: Physiol Behav
Title: The roles of leptin receptors on POMC neurons in the regulation of sex-specific energy homeostasis.
Volume: 100
Issue: 2
Pages: 165-72
Publication
First Author: Madan R
Year: 2014
Journal: Infect Immun
Title: Role of leptin-mediated colonic inflammation in defense against Clostridium difficile colitis.
Volume: 82
Issue: 1
Pages: 341-9
Publication
First Author: Wright DE
Year: 2007
Journal: J Peripher Nerv Syst
Title: Selective changes in nocifensive behavior despite normal cutaneous axon innervation in leptin receptor-null mutant (db/db) mice.
Volume: 12
Issue: 4
Pages: 250-61
Publication
First Author: Chua S Jr
Year: 2010
Journal: Kidney Int
Title: A susceptibility gene for kidney disease in an obese mouse model of type II diabetes maps to chromosome 8.
Volume: 78
Issue: 5
Pages: 453-62
Publication
First Author: Ikeda A
Year: 2014
Journal: Gastroenterology
Title: Leptin receptor somatic mutations are frequent in HCV-infected cirrhotic liver and associated with hepatocellular carcinoma.
Volume: 146
Issue: 1
Pages: 222-32.e35
Publication
First Author: Duffy S
Year: 2018
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Rodent models of leptin receptor deficiency are less sensitive to amylin.
Volume: 315
Issue: 4
Pages: R856-R865
Publication
First Author: Mackey-Lawrence NM
Year: 2013
Journal: Infect Immun
Title: Effect of the leptin receptor Q223R polymorphism on the host transcriptome following infection with Entamoeba histolytica.
Volume: 81
Issue: 5
Pages: 1460-70
Publication
First Author: Gogiraju R
Year: 2023
Journal: Sci Rep
Title: Deletion of endothelial leptin receptors in mice promotes diet-induced obesity.
Volume: 13
Issue: 1
Pages: 8276
Publication  
First Author: Naranjo V
Year: 2020
Journal: Neuroscience
Title: Specific Deletion of the Astrocyte Leptin Receptor Induces Changes in Hippocampus Glutamate Metabolism, Synaptic Transmission and Plasticity.
Volume: 447
Pages: 182-190
Publication  
First Author: Zhang J
Year: 2023
Journal: Front Endocrinol (Lausanne)
Title: The leptin receptor has no role in delta-cell control of beta-cell function in the mouse.
Volume: 14
Pages: 1257671
Publication
First Author: Evans MC
Year: 2017
Journal: Endocrinology
Title: Dopamine Neuron-Restricted Leptin Receptor Signaling Reduces Some Aspects of Food Reward but Exacerbates the Obesity of Leptin Receptor-Deficient Male Mice.
Volume: 158
Issue: 12
Pages: 4246-4256
Publication
First Author: Allison MB
Year: 2015
Journal: Mol Metab
Title: TRAP-seq defines markers for novel populations of hypothalamic and brainstem LepRb neurons.
Volume: 4
Issue: 4
Pages: 299-309
Publication
First Author: Byun HR
Year: 2011
Journal: Neurobiol Dis
Title: Obesity and downregulated hypothalamic leptin receptors in male metallothionein-3-null mice.
Volume: 44
Issue: 1
Pages: 125-32