| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Eidenschenk C |
| Year: |
2008 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Zigzag, a viable mouse Lfng mutation affecting the axial skeleton |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Williams DR |
| Year: |
2014 |
| Journal: |
Dev Biol |
| Title: |
Posterior skeletal development and the segmentation clock period are sensitive to Lfng dosage during somitogenesis. |
| Volume: |
388 |
| Issue: |
2 |
| Pages: |
159-69 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okubo Y |
| Year: |
2012 |
| Journal: |
Nat Commun |
| Title: |
Lfng regulates the synchronized oscillation of the mouse segmentation clock via trans-repression of Notch signalling. |
| Volume: |
3 |
|
| Pages: |
1141 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303867 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303877 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng deltaFCE/deltaFCE |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303867 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303877 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng deltaFCE/deltaFCE |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303867 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303877 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng deltaFCE/deltaFCE |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303867 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303877 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng deltaFCE/deltaFCE |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303867 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303877 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/deltaFCE |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303867 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303877 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/deltaFCE |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303867 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303877 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/deltaFCE |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303867 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303877 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/deltaFCE |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303867 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303877 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/deltaFCE |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/+ |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/+ |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/+ |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/+ |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/deltaFCE |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/deltaFCE |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/deltaFCE |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/deltaFCE |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/deltaFCE |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng deltaFCE/deltaFCE |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng deltaFCE/deltaFCE |
| Detected: |
true |
| Specimen Num: |
17 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng deltaFCE/deltaFCE |
| Detected: |
true |
| Specimen Num: |
18 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng deltaFCE/deltaFCE |
| Detected: |
true |
| Specimen Num: |
20 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng deltaFCE/deltaFCE |
| Detected: |
true |
| Specimen Num: |
21 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303867 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303877 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng deltaFCE/deltaFCE |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303867 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303877 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng deltaFCE/deltaFCE |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303867 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303877 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng deltaFCE/deltaFCE |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303867 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303877 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/deltaFCE |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303867 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303877 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/deltaFCE |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/+ |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/+ |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/deltaFCE |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng +/deltaFCE |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng deltaFCE/deltaFCE |
| Detected: |
true |
| Specimen Num: |
16 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6303869 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675217 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:6303883 |
| Age: |
embryonic day 10.5 |
| Image: |
4 |
|
| Specimen Label: |
Lfng deltaFCE/deltaFCE |
| Detected: |
true |
| Specimen Num: |
19 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bochter MS |
| Year: |
2022 |
| Journal: |
Dev Biol |
| Title: |
Lfng and Dll3 cooperate to modulate protein interactions in cis and coordinate oscillatory Notch pathway activation in the segmentation clock. |
| Volume: |
487 |
|
| Pages: |
42-56 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6323233 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-07-16 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3673919 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:6323241 |
| Age: |
embryonic day 11.0 |
|
| Note: |
No expression in dental epithelium during initiation of tooth development. |
| Specimen Label: |
Lfng E11 not shown |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wahi K |
| Year: |
2017 |
| Journal: |
Dev Dyn |
| Title: |
Putative binding sites for mir-125 family miRNAs in the mouse Lfng 3'UTR affect transcript expression in the segmentation clock, but mir-125a-5p is dispensable for normal somitogenesis. |
| Volume: |
246 |
| Issue: |
10 |
| Pages: |
740-748 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Williams DR |
| Year: |
2016 |
| Journal: |
Development |
| Title: |
Disruption of somitogenesis by a novel dominant allele of Lfng suggests important roles for protein processing and secretion. |
| Volume: |
143 |
| Issue: |
5 |
| Pages: |
822-30 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7789037 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-12-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1666915 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:7789038 |
| Age: |
embryonic day 9.5 |
| Image: |
S4B control |
| Note: |
Lfng is a proneurosensory marker with expression in the ventral region along the anterior-posterior axis at E9.5. |
| Specimen Label: |
S4B control |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1276421 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2008-02-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1675215 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:3772245 |
| Age: |
embryonic day 9.5 |
| Image: |
2E |
| Note: |
Expression is in stripes in the anterior presomitic mesoderm. Ripply2 is coexpressed with these anterior stripes of Lfng mRNA in prospective somites S-I and S0. |
| Specimen Label: |
2E |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1095428 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
1999-06-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1618913 |
| Pattern: |
Not Specified |
| Stage: |
TS13 |
| Assay Id: |
MGI:1337661 |
| Age: |
embryonic day 8.5 |
| Image: |
3.E |
| Note: |
Expression domain overlaps with Dll1 expression domain at the posterior edge of the anterior Lfng stripe, while more caudally they overlap entirely. |
| Specimen Label: |
3.E |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Visan I |
| Year: |
2006 |
| Journal: |
Nat Immunol |
| Title: |
Regulation of T lymphopoiesis by Notch1 and Lunatic fringe-mediated competition for intrathymic niches. |
| Volume: |
7 |
| Issue: |
6 |
| Pages: |
634-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu J |
| Year: |
2006 |
| Journal: |
Development |
| Title: |
Not all lunatic fringe null female mice are infertile. |
| Volume: |
133 |
| Issue: |
4 |
| Pages: |
579; author reply 579-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hahn KL |
| Year: |
2009 |
| Journal: |
Reproduction |
| Title: |
A deficiency of lunatic fringe is associated with cystic dilation of the rete testis. |
| Volume: |
137 |
| Issue: |
1 |
| Pages: |
79-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Akdemir ES |
| Year: |
2022 |
| Journal: |
J Neurosci |
| Title: |
Lunatic Fringe-GFP Marks Lamina-Specific Astrocytes That Regulate Sensory Processing. |
| Volume: |
42 |
| Issue: |
4 |
| Pages: |
567-580 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Serth K |
| Year: |
2003 |
| Journal: |
Genes Dev |
| Title: |
Transcriptional oscillation of lunatic fringe is essential for somitogenesis. |
| Volume: |
17 |
| Issue: |
7 |
| Pages: |
912-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Serth K |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
O-fucosylation of DLL3 is required for its function during somitogenesis. |
| Volume: |
10 |
| Issue: |
4 |
| Pages: |
e0123776 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fisher RE |
| Year: |
2012 |
| Journal: |
Anat Rec (Hoboken) |
| Title: |
Mutations in the Notch pathway alter the patterning of multifidus. |
| Volume: |
295 |
| Issue: |
1 |
| Pages: |
32-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang N |
| Year: |
2000 |
| Journal: |
Curr Biol |
| Title: |
A mutation in the Lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea. |
| Volume: |
10 |
| Issue: |
11 |
| Pages: |
659-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yuan JS |
| Year: |
2011 |
| Journal: |
Blood |
| Title: |
Lunatic Fringe prolongs Delta/Notch-induced self-renewal of committed αβ T-cell progenitors. |
| Volume: |
117 |
| Issue: |
4 |
| Pages: |
1184-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang S |
| Year: |
2015 |
| Journal: |
Cancer Res |
| Title: |
Manic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction. |
| Volume: |
75 |
| Issue: |
10 |
| Pages: |
1936-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kato TM |
| Year: |
2010 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Lunatic fringe potentiates Notch signaling in the developing brain. |
| Volume: |
45 |
| Issue: |
1 |
| Pages: |
12-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Song Y |
| Year: |
2016 |
| Journal: |
J Immunol |
| Title: |
Lunatic, Manic, and Radical Fringe Each Promote T and B Cell Development. |
| Volume: |
196 |
| Issue: |
1 |
| Pages: |
232-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mukherjee S |
| Year: |
2014 |
| Journal: |
J Immunol |
| Title: |
STAT5-induced lunatic fringe during Th2 development alters delta-like 4-mediated Th2 cytokine production in respiratory syncytial virus-exacerbated airway allergic disease. |
| Volume: |
192 |
| Issue: |
3 |
| Pages: |
996-1003 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sparrow DB |
| Year: |
2006 |
| Journal: |
Am J Hum Genet |
| Title: |
Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype. |
| Volume: |
78 |
| Issue: |
1 |
| Pages: |
28-37 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Luther KB |
| Year: |
2009 |
| Journal: |
J Biol Chem |
| Title: |
Structural and mechanistic insights into lunatic fringe from a kinetic analysis of enzyme mutants. |
| Volume: |
284 |
| Issue: |
5 |
| Pages: |
3294-305 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stauber M |
| Year: |
2012 |
| Journal: |
Mech Dev |
| Title: |
Modifying transcript lengths of cycling mouse segmentation genes. |
| Volume: |
129 |
| Issue: |
1-4 |
| Pages: |
61-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kadur Lakshminarasimha Murthy P |
| Year: |
2018 |
| Journal: |
Elife |
| Title: |
Radical and lunatic fringes modulate notch ligands to support mammalian intestinal homeostasis. |
| Volume: |
7 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang N |
| Year: |
2002 |
| Journal: |
Genesis |
| Title: |
Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice. |
| Volume: |
33 |
| Issue: |
1 |
| Pages: |
21-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen J |
| Year: |
2005 |
| Journal: |
Genesis |
| Title: |
Negative feedback loop formed by Lunatic fringe and Hes7 controls their oscillatory expression during somitogenesis. |
| Volume: |
43 |
| Issue: |
4 |
| Pages: |
196-204 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Semerci F |
| Year: |
2017 |
| Journal: |
Elife |
| Title: |
Lunatic fringe-mediated Notch signaling regulates adult hippocampal neural stem cell maintenance. |
| Volume: |
6 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang N |
| Year: |
1998 |
| Journal: |
Nature |
| Title: |
Defects in somite formation in lunatic fringe-deficient mice. |
| Volume: |
394 |
| Issue: |
6691 |
| Pages: |
374-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang S |
| Year: |
2016 |
| Journal: |
Oncogene |
| Title: |
Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer. |
| Volume: |
35 |
| Issue: |
19 |
| Pages: |
2485-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Evrard YA |
| Year: |
1998 |
| Journal: |
Nature |
| Title: |
lunatic fringe is an essential mediator of somite segmentation and patterning. |
| Volume: |
394 |
| Issue: |
6691 |
| Pages: |
377-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okano S |
| Year: |
2005 |
| Journal: |
Jpn J Vet Res |
| Title: |
Examination of the Lunatic fringe and Uncx4.1 expression by whole-mount in situ hybridization in the embryo of the CKH-Jsr (jumbled spine and ribs) mouse. |
| Volume: |
52 |
| Issue: |
4 |
| Pages: |
145-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shifley ET |
| Year: |
2008 |
| Journal: |
Development |
| Title: |
Oscillatory lunatic fringe activity is crucial for segmentation of the anterior but not posterior skeleton. |
| Volume: |
135 |
| Issue: |
5 |
| Pages: |
899-908 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu K |
| Year: |
2012 |
| Journal: |
Cancer Cell |
| Title: |
Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer. |
| Volume: |
21 |
| Issue: |
5 |
| Pages: |
626-41 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
199
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|