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Search results 1 to 100 out of 490 for Lgals3

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Hits by Strain

Type Details Score
Gene
3958 | LGALS3
Type: gene
Organism: human
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Gene
394583 | lgals3
Type: gene
Organism: frog, western clawed
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Gene
83781 | Lgals3
Type: gene
Organism: rat
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Gene
404021 | LGALS3
Type: gene
Organism: dog, domestic
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Gene
744038 | LGALS3
Type: gene
Organism: chimpanzee
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Gene
786492 | LGALS3
Type: gene
Organism: cattle
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Gene
373917 | LGALS3
Type: gene
Organism: chicken
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Gene
697290 | LGALS3
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:96778 | Lgals3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
31745588 | J:328955
First Author: Maupin KA
Year: 2020
Journal: Calcif Tissue Int
Title: Loss of Lgals3 Protects Against Gonadectomy-Induced Cortical Bone Loss in Mice.
Volume: 106
Issue: 3
Pages: 283-293
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GXD Expression
GXD Expression
 
Probe: MGI:7715252
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-10
Strength: Present
Sex: Male
Emaps: EMAPS:1914228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7716436
Age: postnatal week 4
Note: Lgals3 (MAC-2) is a marker for osteoclasts. Staining did not overlap with Fabp5 in the proximal tibia.
Specimen Label: 2a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7715252
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-10
Strength: Present
Sex: Male
Emaps: EMAPS:3789628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7716436
Age: postnatal week 4
Note: Lgals3 (MAC-2) is a marker for osteoclasts. Staining did not overlap with Fabp5 in the proximal tibia.
Specimen Label: 2a
Detected: true
Specimen Num: 1
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Publication
36062328 | J:329549
First Author: Maupin KA
Year: 2022
Journal: FEBS Open Bio
Title: Mutation of the galectin-3 glycan-binding domain (Lgals3-R200S) enhances cortical bone expansion in male mice and trabecular bone mass in female mice.
Volume: 12
Issue: 10
Pages: 1717-1728
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Publication
32674599 | J:318676
First Author: Alencar GF
Year: 2020
Journal: Circulation
Title: Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis.
Volume: 142
Issue: 21
Pages: 2045-2059
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Publication
30886760 | J:278316
 
First Author: Maupin KA
Year: 2018
Journal: Bone Res
Title: Enhanced cortical bone expansion in Lgals3-deficient mice during aging.
Volume: 6
Pages: 7
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Publication
35977543 | J:343754
First Author: Margeta MA
Year: 2022
Journal: Immunity
Title: Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma.
Volume: 55
Issue: 9
Pages: 1627-1644.e7
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Publication
39504243 | J:360636
First Author: Zhong X
Year: 2024
Journal: Cell Rep
Title: Distinct RORγt-dependent Th17 immune responses are required for autoimmune pathogenesis and protection against bacterial infection.
Volume: 43
Issue: 11
Pages: 114951
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Publication
29716523 | J:264129
First Author: Chaudoin TR
Year: 2018
Journal: BMC Neurosci
Title: Mice lacking galectin-3 (Lgals3) function have decreased home cage movement.
Volume: 19
Issue: 1
Pages: 27
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Publication
31231399 | J:281234
 
First Author: Arsenijevic A
Year: 2019
Journal: Front Immunol
Title: Gal-3 Deficiency Suppresses Novosphyngobium aromaticivorans Inflammasome Activation and IL-17 Driven Autoimmune Cholangitis in Mice.
Volume: 10
Pages: 1309
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Publication
21791638 | J:177743
First Author: Darrow AL
Year: 2011
Journal: Physiol Genomics
Title: Transcriptional analysis of the endothelial response to diabetes reveals a role for galectin-3.
Volume: 43
Issue: 20
Pages: 1144-52
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Publication
31006066 | J:295793
First Author: Boza-Serrano A
Year: 2019
Journal: Acta Neuropathol
Title: Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease.
Volume: 138
Issue: 2
Pages: 251-273
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Publication
27226561 | J:235800
First Author: Knights AJ
Year: 2016
Journal: J Biol Chem
Title: Krüppel-like Factor 3 (KLF3/BKLF) Is Required for Widespread Repression of the Inflammatory Modulator Galectin-3 (Lgals3).
Volume: 291
Issue: 31
Pages: 16048-58
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Publication
27385019 | J:234181
First Author: Wang JJ
Year: 2016
Journal: PLoS Genet
Title: Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model.
Volume: 12
Issue: 7
Pages: e1006038
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Publication
34526900 | J:314195
 
First Author: Humphries DC
Year: 2021
Journal: Front Pharmacol
Title: Selective Myeloid Depletion of Galectin-3 Offers Protection Against Acute and Chronic Lung Injury.
Volume: 12
Pages: 715986
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Publication
32295421 | J:292467
First Author: Di Gregoli K
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Galectin-3 Identifies a Subset of Macrophages With a Potential Beneficial Role in Atherosclerosis.
Volume: 40
Issue: 6
Pages: 1491-1509
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Protein Coding Gene
MGP_CAROLIEiJ_G0019166 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021221 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0021169 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0021147 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0021172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020956 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_96778 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021607 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020481 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020922 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0021045 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0021030 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0021115 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0021055 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021640 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0020230 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020537 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030183 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0020054 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10745073 | J:61468
First Author: Menon RP
Year: 2000
Journal: FEBS Lett
Title: Interaction of a novel cysteine and histidine-rich cytoplasmic protein with galectin-3 in a carbohydrate-independent manner.
Volume: 470
Issue: 3
Pages: 227-31
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Publication
2584931 | J:22044
First Author: Cherayil BJ
Year: 1989
Journal: J Exp Med
Title: The Mac-2 antigen is a galactose-specific lectin that binds IgE.
Volume: 170
Issue: 6
Pages: 1959-72
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Publication
3360772 | J:17163
First Author: Jia S
Year: 1988
Journal: J Biol Chem
Title: Carbohydrate binding protein 35. Complementary DNA sequence reveals homology with proteins of the heterogeneous nuclear RNP.
Volume: 263
Issue: 13
Pages: 6009-11
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Publication
2525069 | J:17165
First Author: Raz A
Year: 1989
Journal: Cancer Res
Title: Identification of the metastasis-associated, galactoside-binding lectin as a chimeric gene product with homology to an IgE-binding protein.
Volume: 49
Issue: 13
Pages: 3489-93
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Publication
20053377 | J:159938
First Author: Doverhag C
Year: 2010
Journal: Neurobiol Dis
Title: Galectin-3 contributes to neonatal hypoxic-ischemic brain injury.
Volume: 38
Issue: 1
Pages: 36-46
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Publication
28744198 | J:311983
 
First Author: Chen YC
Year: 2017
Journal: Front Mol Neurosci
Title: Galectin-3 Negatively Regulates Hippocampus-Dependent Memory Formation through Inhibition of Integrin Signaling and Galectin-3 Phosphorylation.
Volume: 10
Pages: 217
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Publication
35163089 | J:325889
 
First Author: Fernández-Martín JC
Year: 2022
Journal: Int J Mol Sci
Title: Gal3 Plays a Deleterious Role in a Mouse Model of Endotoxemia.
Volume: 23
Issue: 3
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Publication
28822790 | J:257078
 
First Author: Simon D
Year: 2017
Journal: Bone
Title: Galectin-3 as a novel regulator of osteoblast-osteoclast interaction and bone homeostasis.
Volume: 105
Pages: 35-41
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Publication
18202187 | J:131371
First Author: Henderson NC
Year: 2008
Journal: Am J Pathol
Title: Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis.
Volume: 172
Issue: 2
Pages: 288-98
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Publication
37208177 | J:353468
First Author: Xue S
Year: 2023
Journal: J Neurosci
Title: Elevated Galectin-3 Is Associated with Aging, Multiple Sclerosis, and Oxidized Phosphatidylcholine-Induced Neurodegeneration.
Volume: 43
Issue: 25
Pages: 4725-4737
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Publication
18202191 | J:131407
First Author: Farnworth SL
Year: 2008
Journal: Am J Pathol
Title: Galectin-3 reduces the severity of pneumococcal pneumonia by augmenting neutrophil function.
Volume: 172
Issue: 2
Pages: 395-405
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Publication
31127200 | J:288672
First Author: Tao CC
Year: 2020
Journal: Cell Death Differ
Title: Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer's disease.
Volume: 27
Issue: 1
Pages: 192-209
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Publication
32703931 | J:305750
First Author: Freitag N
Year: 2020
Journal: Cell Death Dis
Title: Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiency.
Volume: 11
Issue: 7
Pages: 560
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Publication
25215410 | J:225346
 
First Author: Clare DK
Year: 2014
Journal: Nat Commun
Title: Basal foot MTOC organizes pillar MTs required for coordination of beating cilia.
Volume: 5
Pages: 4888
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Publication
18250477 | J:131971
First Author: MacKinnon AC
Year: 2008
Journal: J Immunol
Title: Regulation of alternative macrophage activation by galectin-3.
Volume: 180
Issue: 4
Pages: 2650-8
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Publication
23527230 | J:199906
First Author: Mishra BB
Year: 2013
Journal: PLoS One
Title: Galectin-3 functions as an alarmin: pathogenic role for sepsis development in murine respiratory tularemia.
Volume: 8
Issue: 3
Pages: e59616
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Publication
26002282 | J:225752
 
First Author: Jaquenod De Giusti C
Year: 2015
Journal: J Mol Cell Cardiol
Title: Macrophages and galectin 3 play critical roles in CVB3-induced murine acute myocarditis and chronic fibrosis.
Volume: 85
Pages: 58-70
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Publication
24269916 | J:210375
 
First Author: Young CC
Year: 2014
Journal: Neurobiol Dis
Title: Blocked angiogenesis in Galectin-3 null mice does not alter cellular and behavioral recovery after middle cerebral artery occlusion stroke.
Volume: 63
Pages: 155-64
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Publication
32750085 | J:298152
First Author: Snarr BD
Year: 2020
Journal: PLoS Pathog
Title: Galectin-3 enhances neutrophil motility and extravasation into the airways during Aspergillus fumigatus infection.
Volume: 16
Issue: 8
Pages: e1008741
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Publication
16549783 | J:107656
First Author: Henderson NC
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Galectin-3 regulates myofibroblast activation and hepatic fibrosis.
Volume: 103
Issue: 13
Pages: 5060-5
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Publication
27733579 | J:243513
First Author: Wright RD
Year: 2017
Journal: J Leukoc Biol
Title: Galectin-3-null mice display defective neutrophil clearance during acute inflammation.
Volume: 101
Issue: 3
Pages: 717-726
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Publication
36103788 | J:335475
 
First Author: Zhang C
Year: 2022
Journal: Hear Res
Title: Galectin-3 protects auditory function in female mice.
Volume: 424
Pages: 108602
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Publication
23175698 | J:190845
First Author: Dragomir AC
Year: 2012
Journal: J Immunol
Title: Role of galectin-3 in classical and alternative macrophage activation in the liver following acetaminophen intoxication.
Volume: 189
Issue: 12
Pages: 5934-41
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Publication
30387702 | J:272463
First Author: Nguyen MN
Year: 2019
Journal: Am J Physiol Heart Circ Physiol
Title: Galectin-3 deficiency ameliorates fibrosis and remodeling in dilated cardiomyopathy mice with enhanced Mst1 signaling.
Volume: 316
Issue: 1
Pages: H45-H60
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Publication
21693585 | J:183042
First Author: Comte I
Year: 2011
Journal: J Cell Sci
Title: Galectin-3 maintains cell motility from the subventricular zone to the olfactory bulb.
Volume: 124
Issue: Pt 14
Pages: 2438-47
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Publication
28128358 | J:275158
 
First Author: Yip PK
Year: 2017
Journal: Sci Rep
Title: Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration.
Volume: 7
Pages: 41689
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Publication
32098291 | J:297969
 
First Author: Hafsia N
Year: 2020
Journal: Int J Mol Sci
Title: Galectin 3 Deficiency Alters Chondrocyte Primary Cilium Formation and Exacerbates Cartilage Destruction via Mitochondrial Apoptosis.
Volume: 21
Issue: 4
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Publication
29424570 | J:262287
First Author: Nguyen MN
Year: 2018
Journal: Am J Physiol Heart Circ Physiol
Title: Upregulated galectin-3 is not a critical disease mediator of cardiomyopathy induced by β2-adrenoceptor overexpression.
Volume: 314
Issue: 6
Pages: H1169-H1178
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Publication
37955122 | J:355340
First Author: Sukreet S
Year: 2023
Journal: Am J Physiol Cell Physiol
Title: The absorption of bovine milk small extracellular vesicles largely depends on galectin 3 and galactose ligands in human intestinal cells and C57BL/6J mice.
Volume: 325
Issue: 6
Pages: C1421-C1430
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Publication
25724551 | J:222877
First Author: Sunil VR
Year: 2015
Journal: Toxicol Appl Pharmacol
Title: Regulation of ozone-induced lung inflammation and injury by the β-galactoside-binding lectin galectin-3.
Volume: 284
Issue: 2
Pages: 236-45
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Publication
31311846 | J:282079
 
First Author: AbuSamra DB
Year: 2019
Journal: Sci Signal
Title: Galectin-3 initiates epithelial-stromal paracrine signaling to shape the proteolytic microenvironment during corneal repair.
Volume: 12
Issue: 590
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Publication
26829035 | J:231539
First Author: Walker JT
Year: 2016
Journal: J Invest Dermatol
Title: Genetic Deletion of Galectin-3 Does Not Impair Full-Thickness Excisional Skin Healing.
Volume: 136
Issue: 5
Pages: 1042-50
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Publication
23451284 | J:197183
First Author: Pang J
Year: 2013
Journal: PLoS One
Title: Increased adiposity, dysregulated glucose metabolism and systemic inflammation in Galectin-3 KO mice.
Volume: 8
Issue: 2
Pages: e57915
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Publication
36293342 | J:333896
 
First Author: Al-Salam S
Year: 2022
Journal: Int J Mol Sci
Title: Early Doxorubicin Myocardial Injury: Inflammatory, Oxidative Stress, and Apoptotic Role of Galectin-3.
Volume: 23
Issue: 20
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Publication
17785480 | J:126353
First Author: Breuilh L
Year: 2007
Journal: Infect Immun
Title: Galectin-3 modulates immune and inflammatory responses during helminthic infection: impact of galectin-3 deficiency on the functions of dendritic cells.
Volume: 75
Issue: 11
Pages: 5148-57
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Publication
26948424 | J:231919
First Author: Frunza O
Year: 2016
Journal: Am J Pathol
Title: Myocardial Galectin-3 Expression Is Associated with Remodeling of the Pressure-Overloaded Heart and May Delay the Hypertrophic Response without Affecting Survival, Dysfunction, and Cardiac Fibrosis.
Volume: 186
Issue: 5
Pages: 1114-27
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Publication
26337870 | J:226853
First Author: James RE
Year: 2016
Journal: Glia
Title: Loss of galectin-3 decreases the number of immune cells in the subventricular zone and restores proliferation in a viral model of multiple sclerosis.
Volume: 64
Issue: 1
Pages: 105-21
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Publication
27550173 | J:277251
First Author: Hillis JM
Year: 2016
Journal: J Neuroinflammation
Title: Cuprizone demyelination induces a unique inflammatory response in the subventricular zone.
Volume: 13
Issue: 1
Pages: 190
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Publication
22836271 | J:186539
First Author: Lalancette-Hébert M
Year: 2012
Journal: J Neurosci
Title: Galectin-3 is required for resident microglia activation and proliferation in response to ischemic injury.
Volume: 32
Issue: 30
Pages: 10383-95
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Publication
23117656 | J:216919
First Author: Calvier L
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Galectin-3 mediates aldosterone-induced vascular fibrosis.
Volume: 33
Issue: 1
Pages: 67-75
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Publication
23139902 | J:278839
First Author: Lerman BJ
Year: 2012
Journal: Brain Behav
Title: Deletion of galectin-3 exacerbates microglial activation and accelerates disease progression and demise in a SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
Volume: 2
Issue: 5
Pages: 563-75
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Publication
10702423 | J:60741
First Author: Hsu DK
Year: 2000
Journal: Am J Pathol
Title: Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses.
Volume: 156
Issue: 3
Pages: 1073-83
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Publication
30099675 | J:311792
First Author: Kovacevic MM
Year: 2018
Journal: Immunol Res
Title: Galectin-3 deficiency enhances type 2 immune cell-mediated myocarditis in mice.
Volume: 66
Issue: 4
Pages: 491-502
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Publication
30016630 | J:269663
 
First Author: Mendonça HR
Year: 2018
Journal: Brain Res
Title: Lack of Galectin-3 attenuates neuroinflammation and protects the retina and optic nerve of diabetic mice.
Volume: 1700
Pages: 126-137
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Publication
18845486 | J:143408
First Author: Mensah-Brown EP
Year: 2009
Journal: Clin Immunol
Title: Targeted disruption of the galectin-3 gene results in decreased susceptibility to multiple low dose streptozotocin-induced diabetes in mice.
Volume: 130
Issue: 1
Pages: 83-8
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Publication
28438899 | J:247861
First Author: Gittens BR
Year: 2017
Journal: J Immunol
Title: Galectin-3: A Positive Regulator of Leukocyte Recruitment in the Inflamed Microcirculation.
Volume: 198
Issue: 11
Pages: 4458-4469
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Publication
18843294 | J:150231
First Author: Hsu DK
Year: 2009
Journal: J Invest Dermatol
Title: Endogenous galectin-3 is localized in membrane lipid rafts and regulates migration of dendritic cells.
Volume: 129
Issue: 3
Pages: 573-83
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Publication
33072090 | J:313986
 
First Author: Park AM
Year: 2020
Journal: Front Immunol
Title: Galectin-3 as a Therapeutic Target for NSAID-Induced Intestinal Ulcers.
Volume: 11
Pages: 550366
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Publication
29472568 | J:262581
First Author: de Oliveira FL
Year: 2018
Journal: Sci Rep
Title: Lack of galectin-3 modifies differentially Notch ligands in bone marrow and spleen stromal cells interfering with B cell differentiation.
Volume: 8
Issue: 1
Pages: 3495
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Publication
29432728 | J:274126
 
First Author: Iacobini C
Year: 2018
Journal: Metabolism
Title: Galectin-3 is essential for proper bone cell differentiation and activity, bone remodeling and biomechanical competence in mice.
Volume: 83
Pages: 149-158
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Publication
18825751 | J:142816
First Author: Ferraz LC
Year: 2008
Journal: Eur J Immunol
Title: Lack of galectin-3 alters the balance of innate immune cytokines and confers resistance to Rhodococcus equi infection.
Volume: 38
Issue: 10
Pages: 2762-75
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Publication
23406314 | J:214913
First Author: Mietto BS
Year: 2013
Journal: Eur J Neurosci
Title: Lack of galectin-3 speeds Wallerian degeneration by altering TLR and pro-inflammatory cytokine expressions in injured sciatic nerve.
Volume: 37
Issue: 10
Pages: 1682-90
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Publication
23592449 | J:201022
First Author: Fermino ML
Year: 2013
Journal: Eur J Immunol
Title: Galectin-3 negatively regulates the frequency and function of CD4(+) CD25(+) Foxp3(+) regulatory T cells and influences the course of Leishmania major infection.
Volume: 43
Issue: 7
Pages: 1806-17
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Publication
19229338 | J:146278
First Author: Ruas LP
Year: 2009
Journal: PLoS One
Title: Lack of galectin-3 drives response to Paracoccidioides brasiliensis toward a Th2-biased immunity.
Volume: 4
Issue: 2
Pages: e4519
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Publication
34222228 | J:321266
 
First Author: Ribeiro TN
Year: 2021
Journal: Front Cell Dev Biol
Title: Notch1 and Galectin-3 Modulate Cortical Reactive Astrocyte Response After Brain Injury.
Volume: 9
Pages: 649854
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Publication
19179612 | J:146659
First Author: Saegusa J
Year: 2009
Journal: Am J Pathol
Title: Galectin-3 is critical for the development of the allergic inflammatory response in a mouse model of atopic dermatitis.
Volume: 174
Issue: 3
Pages: 922-31
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