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Search results 1 to 100 out of 378 for Lgr4

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Hits by Strain

Hits by Category

Type Details Score
Gene
55366 | LGR4
Type: gene
Organism: human
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Gene
451088 | LGR4
Type: gene
Organism: chimpanzee
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Gene
505423 | LGR4
Type: gene
Organism: cattle
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Gene
428605 | LGR4
Type: gene
Organism: chicken
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Gene
558825 | lgr4
Type: gene
Organism: zebrafish
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Gene
701736 | LGR4
Type: gene
Organism: macaque, rhesus
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Gene
100144922 | lgr4
Type: gene
Organism: frog, western clawed
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Gene
286994 | Lgr4
Type: gene
Organism: rat
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Gene
476896 | LGR4
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1891468 | Lgr4
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
105376671 | LGR4-AS1
Type: gene
Organism: human
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Publication
30406697 | J:278480
First Author: Li Z
Year: 2019
Journal: Am J Physiol Gastrointest Liver Physiol
Title: LGR4 protects hepatocytes from injury in mouse.
Volume: 316
Issue: 1
Pages: G123-G131
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Publication
26333992 | J:227517
First Author: Koizumi M
Year: 2015
Journal: Biol Reprod
Title: Lgr4 controls specialization of female gonads in mice.
Volume: 93
Issue: 4
Pages: 90
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Publication
29269400 | J:273817
First Author: Yue Z
Year: 2018
Journal: FASEB J
Title: LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells.
Volume: 32
Issue: 5
Pages: 2422-2437
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Publication
32493844 | J:308970
 
First Author: Mancini A
Year: 2020
Journal: JCI Insight
Title: LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling.
Volume: 5
Issue: 11
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Publication
20638054 | J:307452
First Author: Mohri Y
Year: 2010
Journal: Fertil Steril
Title: Reduced fertility with impairment of early-stage embryos observed in mice lacking Lgr4 in epithelial tissues.
Volume: 94
Issue: 7
Pages: 2878-81
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Publication
17850793 | J:126813
First Author: Kato S
Year: 2007
Journal: FEBS Lett
Title: Eye-open at birth phenotype with reduced keratinocyte motility in LGR4 null mice.
Volume: 581
Issue: 24
Pages: 4685-90
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Publication
16406039 | J:105945
First Author: Mendive F
Year: 2006
Journal: Dev Biol
Title: Defective postnatal development of the male reproductive tract in LGR4 knockout mice.
Volume: 290
Issue: 2
Pages: 421-34
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Publication
19301269 | J:174171
First Author: Lambot MA
Year: 2009
Journal: Anat Rec (Hoboken)
Title: Three-dimensional reconstruction of efferent ducts in wild-type and Lgr4 knock-out mice.
Volume: 292
Issue: 4
Pages: 595-603
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Publication
24212090 | J:208298
First Author: Wang J
Year: 2013
Journal: Nat Cell Biol
Title: Ablation of LGR4 promotes energy expenditure by driving white-to-brown fat switch.
Volume: 15
Issue: 12
Pages: 1455-63
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Publication
23897697 | J:204016
First Author: Luo W
Year: 2013
Journal: Stem Cells
Title: Lgr4 is a key regulator of prostate development and prostate stem cell differentiation.
Volume: 31
Issue: 11
Pages: 2492-505
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Publication
32035093 | J:293867
First Author: Ren X
Year: 2020
Journal: J Invest Dermatol
Title: Lgr4 Deletion Delays the Hair Cycle and Inhibits the Activation of Hair Follicle Stem Cells.
Volume: 140
Issue: 9
Pages: 1706-1712.e4
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Publication
24877628 | J:217023
First Author: Pan H
Year: 2014
Journal: Endocrinology
Title: Lgr4 gene regulates corpus luteum maturation through modulation of the WNT-mediated EGFR-ERK signaling pathway.
Volume: 155
Issue: 9
Pages: 3624-37
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Publication
26102032 | J:228673
First Author: Sun Y
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Ablation of Lgr4 enhances energy adaptation in skeletal muscle via activation of Ampk/Sirt1/Pgc1α pathway.
Volume: 464
Issue: 2
Pages: 396-400
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Publication
17079737 | J:121125
First Author: Hoshii T
Year: 2007
Journal: Biol Reprod
Title: LGR4 regulates the postnatal development and integrity of male reproductive tracts in mice.
Volume: 76
Issue: 2
Pages: 303-13
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Publication
30536377 | J:270886
     
First Author: Sun P
Year: 2018
Journal: J Cell Physiol
Title: Loss of Lgr4 inhibits differentiation, migration and apoptosis, and promotes proliferation in bone mesenchymal stem cells.
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Publication
23712846 | J:202723
First Author: Wang Y
Year: 2013
Journal: Stem Cells
Title: Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2.
Volume: 31
Issue: 9
Pages: 1921-31
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Publication
21508962 | J:173765
First Author: Mustata RC
Year: 2011
Journal: EMBO Rep
Title: Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo.
Volume: 12
Issue: 6
Pages: 558-64
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Publication
21693646 | J:198905
First Author: Carmon KS
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling.
Volume: 108
Issue: 28
Pages: 11452-7
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Publication
24353284 | J:216037
First Author: Wang F
Year: 2014
Journal: J Mol Endocrinol
Title: LGR4 acts as a link between the peripheral circadian clock and lipid metabolism in liver.
Volume: 52
Issue: 2
Pages: 133-43
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Publication
27064449 | J:235185
First Author: Luo J
Year: 2016
Journal: Nat Med
Title: LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption.
Volume: 22
Issue: 5
Pages: 539-46
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Publication
22738954 | J:186318
First Author: Mohri Y
Year: 2012
Journal: Biosci Biotechnol Biochem
Title: LGR4 is required for the cell survival of the peripheral mesenchyme at the embryonic stages of nephrogenesis.
Volume: 76
Issue: 5
Pages: 888-91
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Publication
25063812 | J:250415
First Author: Guan X
Year: 2014
Journal: J Biol Chem
Title: Lgr4 protein deficiency induces ataxia-like phenotype in mice and impairs long term depression at cerebellar parallel fiber-Purkinje cell synapses.
Volume: 289
Issue: 38
Pages: 26492-504
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Publication
23975934 | J:203941
First Author: Sone M
Year: 2013
Journal: FASEB J
Title: LGR4 expressed in uterine epithelium is necessary for uterine gland development and contributes to decidualization in mice.
Volume: 27
Issue: 12
Pages: 4917-28
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Publication
23393138 | J:197850
First Author: Liu S
Year: 2013
Journal: J Biol Chem
Title: Lgr4 gene deficiency increases susceptibility and severity of dextran sodium sulfate-induced inflammatory bowel disease in mice.
Volume: 288
Issue: 13
Pages: 8794-803; discussion 8804
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Publication
27693558 | J:237841
First Author: Xu P
Year: 2016
Journal: Cancer Lett
Title: Lgr4 is crucial for skin carcinogenesis by regulating MEK/ERK and Wnt/β-catenin signaling pathways.
Volume: 383
Issue: 2
Pages: 161-170
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Publication
24680895 | J:212415
First Author: Kinzel B
Year: 2014
Journal: Dev Biol
Title: Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice.
Volume: 390
Issue: 2
Pages: 181-90
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Publication
27559308 | J:273440
 
First Author: Żak M
Year: 2016
Journal: Front Cell Neurosci
Title: LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea.
Volume: 10
Pages: 186
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Publication
28634819 | J:252705
First Author: Kriz V
Year: 2017
Journal: Transgenic Res
Title: Establishment of a tagged variant of Lgr4 receptor suitable for functional and expression studies in the mouse.
Volume: 26
Issue: 5
Pages: 689-701
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Publication
25811370 | J:229263
First Author: Zhu J
Year: 2015
Journal: PLoS One
Title: Targeted deletion of the murine Lgr4 gene decreases lens epithelial cell resistance to oxidative stress and induces age-related cataract formation.
Volume: 10
Issue: 3
Pages: e0119599
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Publication
16028069 | J:158050
First Author: Van Schoore G
Year: 2005
Journal: Histochem Cell Biol
Title: Expression pattern of the orphan receptor LGR4/GPR48 gene in the mouse.
Volume: 124
Issue: 1
Pages: 35-50
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Publication
16785743 | J:127019
First Author: Kato S
Year: 2006
Journal: Nephron Exp Nephrol
Title: Leucine-rich repeat-containing G protein-coupled receptor-4 (LGR4, Gpr48) is essential for renal development in mice.
Volume: 104
Issue: 2
Pages: e63-75
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Publication
28768769 | J:246044
First Author: Luo W
Year: 2017
Journal: J Biol Chem
Title: Leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial-mesenchymal transition.
Volume: 292
Issue: 37
Pages: 15525-15537
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Publication
31376385 | J:284290
First Author: Wu J
Year: 2020
Journal: J Invest Dermatol
Title: MicroRNA-34 Family Enhances Wound Inflammation by Targeting LGR4.
Volume: 140
Issue: 2
Pages: 465-476.e11
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Publication
24519938 | J:212439
First Author: Yi T
Year: 2014
Journal: J Biol Chem
Title: LGR4/GPR48 inactivation leads to aniridia-genitourinary anomalies-mental retardation syndrome defects.
Volume: 289
Issue: 13
Pages: 8767-80
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Publication
28842478 | J:246020
First Author: Zhang N
Year: 2017
Journal: J Biol Chem
Title: Leucine-rich repeat-containing G protein-coupled receptor 4 facilitates vesicular stomatitis virus infection by binding vesicular stomatitis virus glycoprotein.
Volume: 292
Issue: 40
Pages: 16527-16538
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Publication
23533175 | J:195273
First Author: Qian Y
Year: 2013
Journal: Development
Title: Lgr4-mediated Wnt/β-catenin signaling in peritubular myoid cells is essential for spermatogenesis.
Volume: 140
Issue: 8
Pages: 1751-61
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Publication
18651655 | J:139012
First Author: Mohri Y
Year: 2008
Journal: Dev Dyn
Title: Impaired hair placode formation with reduced expression of hair follicle-related genes in mice lacking Lgr4.
Volume: 237
Issue: 8
Pages: 2235-42
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Publication
19301403 | J:147036
First Author: Yamashita R
Year: 2009
Journal: Dev Dyn
Title: Defective development of the gall bladder and cystic duct in Lgr4- hypomorphic mice.
Volume: 238
Issue: 4
Pages: 993-1000
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Publication
32926477 | J:306915
First Author: Liu S
Year: 2020
Journal: FASEB J
Title: Rspo1/Rspo3-LGR4 signaling inhibits hepatic cholesterol synthesis through the AMPKα-SREBP2 pathway.
Volume: 34
Issue: 11
Pages: 14946-14959
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Publication
29967265 | J:265563
First Author: Tan B
Year: 2018
Journal: Cancer Res
Title: Inhibition of Rspo-Lgr4 Facilitates Checkpoint Blockade Therapy by Switching Macrophage Polarization.
Volume: 78
Issue: 17
Pages: 4929-4942
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Publication
21523854 | J:172277
First Author: Mohri Y
Year: 2011
Journal: Dev Dyn
Title: Lgr4-deficient mice showed premature differentiation of ureteric bud with reduced expression of Wnt effector Lef1 and Gata3.
Volume: 240
Issue: 6
Pages: 1626-34
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Publication
29859889 | J:264603
First Author: Da Silva F
Year: 2018
Journal: Dev Biol
Title: Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4.
Volume: 441
Issue: 1
Pages: 42-51
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Publication
21727895 | J:174842
First Author: de Lau W
Year: 2011
Journal: Nature
Title: Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.
Volume: 476
Issue: 7360
Pages: 293-7
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Publication
24344199 | J:316107
First Author: Han XH
Year: 2014
Journal: Mol Cell Biol
Title: Regulation of the follistatin gene by RSPO-LGR4 signaling via activation of the WNT/β-catenin pathway in skeletal myogenesis.
Volume: 34
Issue: 4
Pages: 752-64
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Publication
37651925 | J:341172
 
First Author: Watanabe K
Year: 2023
Journal: Gene Expr Patterns
Title: Spatiotemporal expression patterns of R-spondins and their receptors, Lgrs, in the developing mouse telencephalon.
Volume: 49
Pages: 119333
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Publication
15192078 | J:92077
First Author: Mazerbourg S
Year: 2004
Journal: Mol Endocrinol
Title: Leucine-rich repeat-containing, G protein-coupled receptor 4 null mice exhibit intrauterine growth retardation associated with embryonic and perinatal lethality.
Volume: 18
Issue: 9
Pages: 2241-54
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Protein Coding Gene
MGP_CAROLIEiJ_G0024049 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026242 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026203 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026183 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026212 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025962 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1891468 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026664 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025427 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025940 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026078 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026041 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026181 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026065 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026717 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025162 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025494 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025487 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024962 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
20023170 | J:157158
First Author: Li XY
Year: 2010
Journal: Development
Title: G protein-coupled receptor 48 upregulates estrogen receptor alpha expression via cAMP/PKA signaling in the male reproductive tract.
Volume: 137
Issue: 1
Pages: 151-7
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Publication
24595031 | J:214699
First Author: Dang Y
Year: 2014
Journal: PLoS One
Title: Gpr48 deficiency induces polycystic kidney lesions and renal fibrosis in mice by activating Wnt signal pathway.
Volume: 9
Issue: 3
Pages: e89835
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Publication
11401528 | J:68632
First Author: Loh ED
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Molecular characterization of a novel glycoprotein hormone G-protein-coupled receptor.
Volume: 282
Issue: 3
Pages: 757-64
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GXD Expression
GXD Expression
     
Probe: MGI:1933811
Assay Type: Northern blot
Annotation Date: 2001-05-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:1934149
Age: embryonic day 7.0
Specimen Label: 7
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:1933811
Assay Type: Northern blot
Annotation Date: 2001-05-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:1934149
Age: embryonic day 11.0
Specimen Label: 11
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:1933811
Assay Type: Northern blot
Annotation Date: 2001-05-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:1934149
Age: embryonic day 15.0
Specimen Label: 15
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:1933811
Assay Type: Northern blot
Annotation Date: 2001-05-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:1934149
Age: embryonic day 17.0
Specimen Label: 17
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:1933811
Assay Type: Northern blot
Annotation Date: 2006-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3689388
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:1933811
Assay Type: Northern blot
Annotation Date: 2006-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3689388
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:1933811
Assay Type: Northern blot
Annotation Date: 2006-11-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3689388
Age: postnatal adult
Specimen Label: Spleen
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:1933811
Assay Type: Northern blot
Annotation Date: 2006-11-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3689388
Age: postnatal adult
Specimen Label: Lung
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:1933811
Assay Type: Northern blot
Annotation Date: 2006-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3689388
Age: postnatal adult
Specimen Label: Liver
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:1933811
Assay Type: Northern blot
Annotation Date: 2006-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:3689388
Age: postnatal adult
Specimen Label: Muscle
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:1933811
Assay Type: Northern blot
Annotation Date: 2006-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3689388
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:1933811
Assay Type: Northern blot
Annotation Date: 2006-11-30
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3689388
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:5585160
Assay Type: RT-PCR
Annotation Date: 2014-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737323
Stage: TS23
Assay Id: MGI:5585166
Age: embryonic day 15.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5585160
Assay Type: RT-PCR
Annotation Date: 2014-09-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737323
Stage: TS23
Assay Id: MGI:5585166
Age: embryonic day 15.5
Image: 1
Specimen Label: -/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5585160
Assay Type: RT-PCR
Annotation Date: 2014-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737320
Stage: TS20
Assay Id: MGI:5585167
Age: embryonic day 12.5
Image: 1
Specimen Label: E12.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5585160
Assay Type: RT-PCR
Annotation Date: 2014-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737321
Stage: TS21
Assay Id: MGI:5585167
Age: embryonic day 13.5
Image: 1
Specimen Label: E13.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5585160
Assay Type: RT-PCR
Annotation Date: 2014-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737322
Stage: TS22
Assay Id: MGI:5585167
Age: embryonic day 14.5
Image: 1
Specimen Label: E14.5
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5585160
Assay Type: RT-PCR
Annotation Date: 2014-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737323
Stage: TS23
Assay Id: MGI:5585167
Age: embryonic day 15.5
Image: 1
Specimen Label: E15.5
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5585160
Assay Type: RT-PCR
Annotation Date: 2014-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737324
Stage: TS24
Assay Id: MGI:5585167
Age: embryonic day 16.5
Image: 1
Specimen Label: E16.5
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5585160
Assay Type: RT-PCR
Annotation Date: 2014-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737325
Stage: TS25
Assay Id: MGI:5585167
Age: embryonic day 17.5
Image: 1
Specimen Label: E17.5
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5585160
Assay Type: RT-PCR
Annotation Date: 2014-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737327
Stage: TS27
Assay Id: MGI:5585167
Age: postnatal day 0
Image: 1
Specimen Label: P0
Detected: true
Specimen Num: 7
•
•
•
•
•




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