|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 1002 for Lhx3

<< First    < Previous  |  Next >    Last >>
0.052s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: guinea pig
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Zhadanov AB
Year: 1995
Journal: Dev Dyn
Title: Expression pattern of the murine LIM class homeobox gene Lhx3 in subsets of neural and neuroendocrine tissues.
Volume: 202
Issue: 4
Pages: 354-64
Publication
First Author: Hume CR
Year: 2007
Journal: Gene Expr Patterns
Title: Expression of LHX3 and SOX2 during mouse inner ear development.
Volume: 7
Issue: 7
Pages: 798-807
Publication
First Author: Charles MA
Year: 2005
Journal: Mol Endocrinol
Title: PITX genes are required for cell survival and Lhx3 activation.
Volume: 19
Issue: 7
Pages: 1893-903
Publication
First Author: Sharma K
Year: 1998
Journal: Cell
Title: LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons.
Volume: 95
Issue: 6
Pages: 817-28
Publication
First Author: Sloop KW
Year: 1999
Journal: Mol Endocrinol
Title: Differential activation of pituitary hormone genes by human Lhx3 isoforms with distinct DNA binding properties.
Volume: 13
Issue: 12
Pages: 2212-25
Publication
First Author: Netchine I
Year: 2000
Journal: Nat Genet
Title: Mutations in LHX3 result in a new syndrome revealed by combined pituitary hormone deficiency.
Volume: 25
Issue: 2
Pages: 182-6
Publication
First Author: Tian G
Year: 2008
Journal: Dev Dyn
Title: Expression and function of the LIM homeobox containing genes Lhx3 and Lhx4 in the mouse placenta.
Volume: 237
Issue: 5
Pages: 1517-25
Publication
First Author: Sloop KW
Year: 2000
Journal: Gene
Title: Analysis of the human LHX3 neuroendocrine transcription factor gene and mapping to the subtelomeric region of chromosome 9.
Volume: 245
Issue: 2
Pages: 237-43
Publication
First Author: Fiorenza MT
Year: 2001
Journal: Gene
Title: Expression screening for Lhx3 downstream genes identifies Thg-1pit as a novel mouse gene involved in pituitary development.
Volume: 278
Issue: 1-2
Pages: 125-30
Publication
First Author: Seo SY
Year: 2015
Journal: Mol Cell Biol
Title: Critical Roles of the LIM Domains of Lhx3 in Recruiting Coactivators to the Motor Neuron-Specifying Isl1-Lhx3 Complex.
Volume: 35
Issue: 20
Pages: 3579-89
Publication
First Author: Colvin SC
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Model of pediatric pituitary hormone deficiency separates the endocrine and neural functions of the LHX3 transcription factor in vivo.
Volume: 108
Issue: 1
Pages: 173-8
Publication
First Author: Sloop KW
Year: 2001
Journal: J Biol Chem
Title: An isoform-specific inhibitory domain regulates the LHX3 LIM homeodomain factor holoprotein and the production of a functional alternate translation form.
Volume: 276
Issue: 39
Pages: 36311-9
GXD Expression    
Probe: MGI:6176420
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190710
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Lhx3
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6176420
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190710
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Lhx3
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6176420
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190710
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Lhx3
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6176420
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190710
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Lhx3
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6176420
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190710
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Lhx3
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6176420
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190710
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Lhx3
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6176420
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190710
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Lhx3
Detected: true
Specimen Num: 7
Publication
First Author: Seidah NG
Year: 1994
Journal: DNA Cell Biol
Title: The mouse homeoprotein mLIM-3 is expressed early in cells derived from the neuroepithelium and persists in adult pituitary.
Volume: 13
Issue: 12
Pages: 1163-80
Publication
First Author: Bach I
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: P-Lim, a LIM homeodomain factor, is expressed during pituitary organ and cell commitment and synergizes with Pit-1.
Volume: 92
Issue: 7
Pages: 2720-4
Publication
First Author: Prince KL
Year: 2013
Journal: Endocrinology
Title: Developmental analysis and influence of genetic background on the Lhx3 W227ter mouse model of combined pituitary hormone deficiency disease.
Volume: 154
Issue: 2
Pages: 738-48
Publication
First Author: Zhao Y
Year: 2006
Journal: Mech Dev
Title: Reduced expression of the LIM-homeobox gene Lhx3 impairs growth and differentiation of Rathke's pouch and increases cell apoptosis during mouse pituitary development.
Volume: 123
Issue: 8
Pages: 605-13
GXD Expression  
Probe: MGI:1859950
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757920
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7432593
Age: embryonic day 12.5
Note: Motor neurons that marked by Lhx3 were lost.
Specimen Label: 5A -/-
Detected: true
Specimen Num: 2
Publication
First Author: Bhati M
Year: 2008
Journal: EMBO J
Title: Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes.
Volume: 27
Issue: 14
Pages: 2018-29
GXD Expression
Probe: MGI:1202629
Assay Type: RNA in situ
Annotation Date: 1998-12-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672515
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:1316698
Age: embryonic day 9.5
Image: e9.5
Note: Expression of Lhx3 is initiated at the 20 somite stage in the dorsal domain of Rathke's pouch.
Specimen Label: e9.5
Detected: true
Specimen Num: 2
Publication
First Author: Glenn DJ
Year: 1999
Journal: J Biol Chem
Title: MRG1 binds to the LIM domain of Lhx2 and may function as a coactivator to stimulate glycoprotein hormone alpha-subunit gene expression.
Volume: 274
Issue: 51
Pages: 36159-67
GXD Expression
Probe: MGI:1202629
Assay Type: RNA in situ
Annotation Date: 1998-12-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751420
Pattern: Graded
Stage: TS20
Assay Id: MGI:1316698
Age: embryonic day 12.5
Image: e12.5
Note: There is a high level of Lhx3 in the dorsal domain of the anterior pituitary, a moderate level in the intermediate domain and a very low level in the ventral domain.
Specimen Label: e12.5
Detected: true
Specimen Num: 5
Publication
First Author: Shirasaki R
Year: 2006
Journal: Neuron
Title: FGF as a target-derived chemoattractant for developing motor axons genetically programmed by the LIM code.
Volume: 50
Issue: 6
Pages: 841-53
UniProt Feature
Begin: 1
Description: LIM/homeobox protein Lhx3
Type: chain
End: 400
Publication
First Author: Miyamoto T
Year: 2003
Journal: Dev Genes Evol
Title: Molecular cloning and expression analysis of the mouse Spot-2 gene in pituitary development.
Volume: 213
Issue: 4
Pages: 199-202
Publication
First Author: Xu M
Year: 2018
Journal: Genesis
Title: Generation and characterization of Lhx3GFP reporter knockin and Lhx3loxP conditional knockout mice.
Volume: 56
Issue: 4
Pages: e23098
Publication
First Author: Sheng HZ
Year: 1997
Journal: Science
Title: Multistep control of pituitary organogenesis.
Volume: 278
Issue: 5344
Pages: 1809-12
Publication
First Author: Sheng HZ
Year: 1996
Journal: Science
Title: Specification of pituitary cell lineages by the LIM homeobox gene Lhx3.
Volume: 272
Issue: 5264
Pages: 1004-7
Publication
First Author: Lee S
Year: 2008
Journal: Dev Cell
Title: A regulatory network to segregate the identity of neuronal subtypes.
Volume: 14
Issue: 6
Pages: 877-89
Publication
First Author: Al-Mosawie A
Year: 2007
Journal: Eur J Neurosci
Title: Heterogeneity of V2-derived interneurons in the adult mouse spinal cord.
Volume: 26
Issue: 11
Pages: 3003-15
Publication
First Author: Lee S
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Fusion protein Isl1-Lhx3 specifies motor neuron fate by inducing motor neuron genes and concomitantly suppressing the interneuron programs.
Volume: 109
Issue: 9
Pages: 3383-8
Publication
First Author: Lee SK
Year: 2003
Journal: Neuron
Title: Synchronization of neurogenesis and motor neuron specification by direct coupling of bHLH and homeodomain transcription factors.
Volume: 38
Issue: 5
Pages: 731-45
Publication    
First Author: Kim Y
Year: 2017
Journal: Elife
Title: The LIM protein complex establishes a retinal circuitry of visual adaptation by regulating Pax6 α-enhancer activity.
Volume: 6
Publication
First Author: Bretzner F
Year: 2013
Journal: J Neurosci
Title: Lhx3-Chx10 reticulospinal neurons in locomotor circuits.
Volume: 33
Issue: 37
Pages: 14681-92
Publication
First Author: Hinckley CA
Year: 2015
Journal: Neuron
Title: Spinal Locomotor Circuits Develop Using Hierarchical Rules Based on Motorneuron Position and Identity.
Volume: 87
Issue: 5
Pages: 1008-21
Publication
First Author: Hertzano R
Year: 2007
Journal: Eur J Neurosci
Title: Lhx3, a LIM domain transcription factor, is regulated by Pou4f3 in the auditory but not in the vestibular system.
Volume: 25
Issue: 4
Pages: 999-1005
Publication
First Author: Raetzman LT
Year: 2002
Journal: Development
Title: Lhx4 and Prop1 are required for cell survival and expansion of the pituitary primordia.
Volume: 129
Issue: 18
Pages: 4229-39
Publication
First Author: Gergics P
Year: 2015
Journal: Mol Endocrinol
Title: Lhx4 deficiency: increased cyclin-dependent kinase inhibitor expression and pituitary hypoplasia.
Volume: 29
Issue: 4
Pages: 597-612
Publication
First Author: Joshi K
Year: 2009
Journal: Neuron
Title: LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons.
Volume: 61
Issue: 6
Pages: 839-51
Publication
First Author: Kim N
Year: 2015
Journal: PLoS Genet
Title: Functional Diversification of Motor Neuron-specific Isl1 Enhancers during Evolution.
Volume: 11
Issue: 10
Pages: e1005560
Publication
First Author: Stallings CE
Year: 2018
Journal: Endocrinology
Title: Premature Expression of FOXO1 in Developing Mouse Pituitary Results in Anterior Lobe Hypoplasia.
Volume: 159
Issue: 8
Pages: 2891-2904
Publication
First Author: Zhadanov AB
Year: 1995
Journal: Genomics
Title: Genomic structure and chromosomal localization of the mouse LIM/homeobox gene Lhx3.
Volume: 27
Issue: 1
Pages: 27-32
Publication
First Author: Chou SJ
Year: 2006
Journal: Dev Biol
Title: Conserved regulatory elements establish the dynamic expression of Rpx/HesxI in early vertebrate development.
Volume: 292
Issue: 2
Pages: 533-45
Publication
First Author: Potok MA
Year: 2008
Journal: Dev Dyn
Title: WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth.
Volume: 237
Issue: 4
Pages: 1006-20
Publication
First Author: Gumbel JH
Year: 2012
Journal: PLoS One
Title: The forkhead transcription factor, Foxd1, is necessary for pituitary luteinizing hormone expression in mice.
Volume: 7
Issue: 12
Pages: e52156
Publication
First Author: Wang W
Year: 2022
Journal: Nat Commun
Title: The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development.
Volume: 13
Issue: 1
Pages: 958
Allele
Name: LIM homeobox protein 3; targeted mutation 1.3, Lin Gan
Allele Type: Targeted
Attribute String: Null/knockout
Publication
First Author: Takuma N
Year: 1998
Journal: Development
Title: Formation of Rathke's pouch requires dual induction from the diencephalon.
Volume: 125
Issue: 23
Pages: 4835-40
Publication
First Author: Ellsworth BS
Year: 2006
Journal: Mol Endocrinol
Title: FOXL2 in the pituitary: molecular, genetic, and developmental analysis.
Volume: 20
Issue: 11
Pages: 2796-805
Publication
First Author: Morikawa Y
Year: 2009
Journal: Dev Neurosci
Title: Detailed expression pattern of Foxp1 and its possible roles in neurons of the spinal cord during embryogenesis.
Volume: 31
Issue: 6
Pages: 511-22
Publication
First Author: Ellsworth BS
Year: 2008
Journal: Dev Biol
Title: Mechanisms underlying pituitary hypoplasia and failed cell specification in Lhx3-deficient mice.
Volume: 313
Issue: 1
Pages: 118-29
Publication
First Author: Balasubramanian R
Year: 2014
Journal: Gene Expr Patterns
Title: Expression of LIM-homeodomain transcription factors in the developing and mature mouse retina.
Volume: 14
Issue: 1
Pages: 1-8
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Wang L
Year: 2008
Journal: Neurobiol Dis
Title: Restricted expression of mutant SOD1 in spinal motor neurons and interneurons induces motor neuron pathology.
Volume: 29
Issue: 3
Pages: 400-8
Publication
First Author: Wilson JM
Year: 2007
Journal: J Neurophysiol
Title: Two-photon calcium imaging of network activity in XFP-expressing neurons in the mouse.
Volume: 97
Issue: 4
Pages: 3118-25
Publication  
First Author: Toenjes SA
Year: 1999
Journal: Parasitology
Title: The systemic immune response of BALB/c mice infected with larval Taenia crassiceps is a mixed Th1/Th2-type response.
Volume: 118 ( Pt 6)
Pages: 623-33
GXD Expression      
Probe: MGI:5000145
Assay Type: Northern blot
Annotation Date: 2011-05-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5000146
Age: postnatal adult
Specimen Label: Liver
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5000145
Assay Type: Northern blot
Annotation Date: 2011-05-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5000146
Age: postnatal adult
Specimen Label: Cortex
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:5000145
Assay Type: Northern blot
Annotation Date: 2011-05-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:5000146
Age: postnatal adult
Specimen Label: Hippocampus
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:5000145
Assay Type: Northern blot
Annotation Date: 2011-05-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:5000146
Age: postnatal adult
Specimen Label: Striatum
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:5000145
Assay Type: Northern blot
Annotation Date: 2011-05-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754028
Stage: TS28
Assay Id: MGI:5000146
Age: postnatal adult
Specimen Label: Thalamus
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:5000145
Assay Type: Northern blot
Annotation Date: 2011-05-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1753628
Stage: TS28
Assay Id: MGI:5000146
Age: postnatal adult
Specimen Label: Hypothalamus
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:5000145
Assay Type: Northern blot
Annotation Date: 2011-05-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5000146
Age: postnatal adult
Specimen Label: Cerebellum
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:5000145
Assay Type: Northern blot
Annotation Date: 2011-05-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751428
Stage: TS28
Assay Id: MGI:5000146
Age: postnatal adult
Specimen Label: Anterior Lobe
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5000145
Assay Type: Northern blot
Annotation Date: 2011-05-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751928
Stage: TS28
Assay Id: MGI:5000146
Age: postnatal adult
Specimen Label: Neurointermediate Lobe
Detected: true
Specimen Num: 9