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Search results 1 to 89 out of 89 for Lim2

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Hits by Category

Hits by Strain

Type Details Score
Gene
3982 | LIM2
Type: gene
Organism: human
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Gene
100124809 | lim2
Type: gene
Organism: frog, western clawed
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Gene
281282 | LIM2
Type: gene
Organism: cattle
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Gene
114903 | Lim2
Type: gene
Organism: rat
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Gene
748793 | LIM2
Type: gene
Organism: chimpanzee
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Gene
100856095 | LIM2
Type: gene
Organism: dog, domestic
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Gene
719639 | LIM2
Type: gene
Organism: macaque, rhesus
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Gene
101749931 | LIM2
Type: gene
Organism: chicken
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Protein Coding Gene
MGI:104698 | Lim2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
8666393 | J:29219
First Author: Kerscher S
Year: 1995
Journal: Genomics
Title: Mapping of four mouse genes encoding eye lens-specific structural, gap junction, and integral membrane proteins: Cryba1 (crystallin beta A3/A1), Crybb2 (crystallin beta B2), Gja8 (MP70), and Lim2 (MP19).
Volume: 29
Issue: 2
Pages: 445-50
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Gene
105372446 | LIM2-AS1
Type: gene
Organism: human
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Publication
9238094 | J:46338
 
First Author: Steele EC Jr
Year: 1997
Journal: Mol Vis
Title: Identification of a mutation in the MP19 gene, Lim2, in the cataractous mouse mutant To3.
Volume: 3
Pages: 5
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Publication
17251442 | J:123284
First Author: Shiels A
Year: 2007
Journal: Invest Ophthalmol Vis Sci
Title: Refractive defects and cataracts in mice lacking lens intrinsic membrane protein-2.
Volume: 48
Issue: 2
Pages: 500-8
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Publication
21617753 | J:179533
 
First Author: Puk O
Year: 2011
Journal: Mol Vis
Title: Microphakia and congenital cataract formation in a novel Lim2(C51R) mutant mouse.
Volume: 17
Pages: 1164-71
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Publication
21775657 | J:181598
First Author: Shi Y
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Further analysis of the lens phenotype in Lim2-deficient mice.
Volume: 52
Issue: 10
Pages: 7332-9
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Publication
12097863 | J:80745
 
First Author: Zhou L
Year: 2002
Journal: Mol Vis
Title: Temporal expression of three mouse lens fiber cell membrane protein genes during early development.
Volume: 8
Pages: 143-8
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Publication
8812411 | J:34877
First Author: Kerscher S
Year: 1996
Journal: Genomics
Title: Two new cataract loci, Ccw and To3, and further mapping of the Npp and Opj cataracts in the mouse.
Volume: 36
Issue: 1
Pages: 17-21
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Protein Coding Gene
MGI_C57BL6J_104698 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
19401333 | J:150486
First Author: Shi Y
Year: 2009
Journal: J Cell Sci
Title: The stratified syncytium of the vertebrate lens.
Volume: 122
Issue: Pt 10
Pages: 1607-15
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GXD Expression
GXD Expression
     
Probe: MGI:6360892
Assay Type: RT-PCR
Annotation Date: 2019-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:6360896
Age: postnatal adult
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6360892
Assay Type: RT-PCR
Annotation Date: 2019-09-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603914
Stage: TS14
Assay Id: MGI:6360896
Age: embryonic day 9.0
Specimen Label: 4
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6360892
Assay Type: RT-PCR
Annotation Date: 2019-09-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6360896
Age: embryonic day 9.5
Specimen Label: 5
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6360892
Assay Type: RT-PCR
Annotation Date: 2019-09-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603916
Stage: TS16
Assay Id: MGI:6360896
Age: embryonic day 10.0
Specimen Label: 6
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6360892
Assay Type: RT-PCR
Annotation Date: 2019-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6360896
Age: embryonic day 10.5
Specimen Label: 7
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:6360892
Assay Type: RT-PCR
Annotation Date: 2019-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185818
Stage: TS18
Assay Id: MGI:6360896
Age: embryonic day 11.0
Specimen Label: 8
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:6360892
Assay Type: RT-PCR
Annotation Date: 2019-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185819
Stage: TS19
Assay Id: MGI:6360896
Age: embryonic day 11.5
Specimen Label: 9
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:6360892
Assay Type: RT-PCR
Annotation Date: 2019-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185820
Stage: TS20
Assay Id: MGI:6360896
Age: embryonic day 12.0
Specimen Label: 10
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:6360892
Assay Type: RT-PCR
Annotation Date: 2019-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185820
Stage: TS20
Assay Id: MGI:6360896
Age: embryonic day 12.5
Specimen Label: 11
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:6360892
Assay Type: RT-PCR
Annotation Date: 2019-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185821
Stage: TS21
Assay Id: MGI:6360896
Age: embryonic day 13.0
Specimen Label: 12
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:287799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801823
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825925
Age: embryonic day 14.5
Image: euxassay_000148_02
Specimen Label: euxassay_000148_02
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:287799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801823
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825925
Age: embryonic day 14.5
Image: euxassay_000148_03
Specimen Label: euxassay_000148_03
Detected: true
Specimen Num: 2
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Publication
7088001 | J:23988
First Author: Ehling UH
Year: 1982
Journal: Mutat Res
Title: Dominant cataract mutations and specific-locus mutations in mice induced by radiation or ethylnitrosourea.
Volume: 92
Issue: 1-2
Pages: 181-92
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Publication
6510713 | J:51161
First Author: Favor J
Year: 1984
Journal: Genet Res
Title: Characterization of dominant cataract mutations in mice: penetrance, fertility and homozygous viability of mutations recovered after 250 mg/kg ethylnitrosourea paternal treatment.
Volume: 44
Issue: 2
Pages: 183-97
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Publication
- | J:67683
   
First Author: Church RL
Year: 2001
Journal: GenBank Submission
Title: Mus musculus lens intrinsic membrane protein 2 (Lim2) and granule membrane protein (Nkg7) genes, complete cds
Pages: AF320075
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Publication
6877261 | J:21950
First Author: Favor J
Year: 1983
Journal: Mutat Res
Title: A comparison of the dominant cataract and recessive specific-locus mutation rates induced by treatment of male mice with ethylnitrosourea.
Volume: 110
Issue: 2
Pages: 367-82
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Publication
15922675 | J:99528
First Author: Joksimovic M
Year: 2005
Journal: Gene Expr Patterns
Title: Dynamic expression of murine HOXA5 protein in the central nervous system.
Volume: 5
Issue: 6
Pages: 792-800
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Publication
15331780 | J:92405
First Author: Angata T
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Large-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanisms.
Volume: 101
Issue: 36
Pages: 13251-6
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Publication
21698205 | J:174785
First Author: Luu B
Year: 2011
Journal: PLoS One
Title: The lineage contribution and role of Gbx2 in spinal cord development.
Volume: 6
Issue: 6
Pages: e20940
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Publication
8812484 | J:34617
First Author: Stubbs L
Year: 1996
Journal: Genomics
Title: Detailed comparative map of human chromosome 19q and related regions of the mouse genome.
Volume: 35
Issue: 3
Pages: 499-508
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Domain
IPR033726 | LIM2_prickle
Type: Domain
Description: Prickle has been implicated in regulation of cell movement in the planar cell polarity (PCP) pathway [], which requires the conserved Frizzled/Dishevelled (Dsh). Prickle interacts with Dishevelled [], thereby modulating the activity of Frizzled/Dishevelled and the PCP signaling. Two forms of prickle have been identified, namely prickle 1 and prickle 2. These are differentially expressed; prickle 1 is found in fetal heart and hematological malignancies, while prickle 2 is expressed in fetal brain, adult cartilage, pancreatic islet, and some types of tumorous cells [].Prickle contains an N-terminal PET domain and three C-terminal LIM domains. LIM domains are 50-60 amino acids in size and share two characteristic zinc finger motifs []. The two zinc fingers contain eight conserved residues, mostly cysteines and histidines, which coordinately bond to two zinc atoms. LIM domains function as adaptors or scaffolds to support the assembly of multimeric protein complexes.This entry represents the second LIM domain of prickle.
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Publication
10851259 | J:100078
 
First Author: Steele EC Jr
Year: 2000
Journal: Mol Vis
Title: Lim2(To3) transgenic mice establish a causative relationship between the mutation identified in the lim2 gene and cataractogenesis in the To3 mouse mutant.
Volume: 6
Pages: 85-94
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Allele
Tg(Lim2*G15V)1Rlc | MGI:3606782
Name: transgene insertion 1, Robert L Church
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Protein Coding Gene
MGI:107792 | Lhx5
Type: protein_coding_gene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Tg(Lim2*G15V)1Rlc/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Lim2*G15V)1Rlc/Tg(Lim2*G15V)1Rlc
Background: involves: C57BL/6 * SJL
Zygosity: hm
Has Mutant Allele: true
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Allele
Lim2<To3> | MGI:1862040
 
Name: lens intrinsic membrane protein 2; total opacity 3
Allele Type: Chemically induced (ENU)
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Publication
12525887 | J:81511
First Author: Katoh M
Year: 2003
Journal: Int J Mol Med
Title: Identification and characterization of human PRICKLE1 and PRICKLE2 genes as well as mouse Prickle1 and Prickle2 genes homologous to Drosophila tissue polarity gene prickle.
Volume: 11
Issue: 2
Pages: 249-56
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Publication
15937478 | -
First Author: Jenny A
Year: 2005
Journal: Nat Cell Biol
Title: Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding.
Volume: 7
Issue: 7
Pages: 691-7
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Publication
12874125 | -
First Author: Carreira-Barbosa F
Year: 2003
Journal: Development
Title: Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish.
Volume: 130
Issue: 17
Pages: 4037-46
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Transgene
MGI:3606781 | Tg(Lim2*G15V)1Rlc
Type: transgene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Lim2/Lim2<+>
Background: involves: 102 * C3H/He * T STOCK
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lim2/Lim2
Background: involves: 102 * C3H/He * T STOCK
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110263 | cataract 19 multiple types
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Protein
Q3U5C7
Organism: Mus musculus/domesticus
Length: 832  
Fragment?: false
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Protein
Q80Y24
Organism: Mus musculus/domesticus
Length: 845  
Fragment?: false
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Protein
Q80VL3
Organism: Mus musculus/domesticus
Length: 624  
Fragment?: false
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Protein
A7YQ68
Organism: Mus musculus/domesticus
Length: 901  
Fragment?: false
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Protein
Q8CIL5
Organism: Mus musculus/domesticus
Length: 649  
Fragment?: true
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Protein
Q8BNH2
Organism: Mus musculus/domesticus
Length: 556  
Fragment?: false
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Publication
15520811 | -
First Author: Kadrmas JL
Year: 2004
Journal: Nat Rev Mol Cell Biol
Title: The LIM domain: from the cytoskeleton to the nucleus.
Volume: 5
Issue: 11
Pages: 920-31
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Publication
10835633 | J:62550
First Author: Netchine I
Year: 2000
Journal: Nat Genet
Title: Mutations in LHX3 result in a new syndrome revealed by combined pituitary hormone deficiency.
Volume: 25
Issue: 2
Pages: 182-6
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Publication
15911088 | J:99031
First Author: Terano T
Year: 2005
Journal: Exp Hematol
Title: Transcriptional control of fetal liver hematopoiesis: dominant negative effect of the overexpression of the LIM domain mutants of LMO2.
Volume: 33
Issue: 6
Pages: 641-51
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom