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Search results 1 to 100 out of 1329 for Lox

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Lee VS
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans.
Volume: 113
Issue: 31
Pages: 8759-64
Publication
First Author: Gabay Yehezkely R
Year: 2020
Journal: Dev Cell
Title: Intracellular Role for the Matrix-Modifying Enzyme Lox in Regulating Transcription Factor Subcellular Localization and Activity in Muscle Regeneration.
Volume: 53
Issue: 4
Pages: 406-417.e5
Publication
First Author: Mäki JM
Year: 2002
Journal: Circulation
Title: Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice.
Volume: 106
Issue: 19
Pages: 2503-9
Publication  
First Author: Calabro NE
Year: 2019
Journal: Matrix Biol
Title: Thrombospondin-2 regulates extracellular matrix production, LOX levels, and cross-linking via downregulation of miR-29.
Volume: 82
Pages: 71-85
Publication
First Author: Spurney CF
Year: 2008
Journal: Neuromuscul Disord
Title: Dystrophin-deficient cardiomyopathy in mouse: expression of Nox4 and Lox are associated with fibrosis and altered functional parameters in the heart.
Volume: 18
Issue: 5
Pages: 371-81
Strain
Attribute String: targeted mutation, mutant strain, congenic
Publication
First Author: Erler JT
Year: 2009
Journal: Cancer Cell
Title: Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche.
Volume: 15
Issue: 1
Pages: 35-44
Publication
First Author: Hornstra IK
Year: 2003
Journal: J Biol Chem
Title: Lysyl oxidase is required for vascular and diaphragmatic development in mice.
Volume: 278
Issue: 16
Pages: 14387-93
Publication
First Author: Kim D
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Downregulation of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose-Induced Apoptosis.
Volume: 58
Issue: 5
Pages: 2725-2731
Publication    
First Author: Lee VS
Year: 2019
Journal: JCI Insight
Title: Intracellular retention of mutant lysyl oxidase leads to aortic dilation in response to increased hemodynamic stress.
Volume: 5
Publication  
First Author: Tsang KM
Year: 2022
Journal: Int J Mol Sci
Title: Copper-Binding Domain Variation in a Novel Murine Lysyl Oxidase Model Produces Structurally Inferior Aortic Elastic Fibers Whose Failure Is Modified by Age, Sex, and Blood Pressure.
Volume: 23
Issue: 12
Publication  
First Author: Peymanfar Y
Year: 2023
Journal: Int J Mol Sci
Title: The Lysyl Oxidase G473A Polymorphism Exacerbates Oral Cancer Development in Humans and Mice.
Volume: 24
Issue: 11
Publication
First Author: Li PA
Year: 2004
Journal: Brain Res Mol Brain Res
Title: Up-regulation and altered distribution of lysyl oxidase in the central nervous system of mutant SOD1 transgenic mouse model of amyotrophic lateral sclerosis.
Volume: 120
Issue: 2
Pages: 115-22
Publication
First Author: Liu SB
Year: 2016
Journal: FASEB J
Title: Lysyl oxidase activity contributes to collagen stabilization during liver fibrosis progression and limits spontaneous fibrosis reversal in mice.
Volume: 30
Issue: 4
Pages: 1599-609
Publication
First Author: Harlow CR
Year: 2017
Journal: PLoS One
Title: Targeting lysyl oxidase reduces peritoneal fibrosis.
Volume: 12
Issue: 8
Pages: e0183013
Publication
First Author: Galán M
Year: 2017
Journal: FASEB J
Title: Lysyl oxidase overexpression accelerates cardiac remodeling and aggravates angiotensin II-induced hypertrophy.
Volume: 31
Issue: 9
Pages: 3787-3799
Publication
First Author: Zhong Y
Year: 2022
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Lysyl oxidase regulation and protein aldehydes in the injured newborn lung.
Volume: 322
Issue: 2
Pages: L204-L223
Publication  
First Author: Wiel C
Year: 2013
Journal: Cell Death Dis
Title: Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis.
Volume: 4
Pages: e855
Publication  
First Author: Aviram R
Year: 2019
Journal: Matrix Biol
Title: Interactions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families.
Volume: 75-76
Pages: 114-125
Publication
First Author: Staiculescu MC
Year: 2017
Journal: Am J Physiol Heart Circ Physiol
Title: Mechanical behavior and matrisome gene expression in the aneurysm-prone thoracic aorta of newborn lysyl oxidase knockout mice.
Volume: 313
Issue: 2
Pages: H446-H456
Publication  
First Author: Noda K
Year: 2020
Journal: Sci Adv
Title: A matricellular protein fibulin-4 is essential for the activation of lysyl oxidase.
Volume: 6
Issue: 48
Publication
First Author: Atsawasuwan P
Year: 2008
Journal: J Biol Chem
Title: Lysyl oxidase binds transforming growth factor-beta and regulates its signaling via amine oxidase activity.
Volume: 283
Issue: 49
Pages: 34229-40
Publication
First Author: Hayashi K
Year: 2004
Journal: J Mol Histol
Title: Comparative immunocytochemical localization of lysyl oxidase (LOX) and the lysyl oxidase-like (LOXL) proteins: changes in the expression of LOXL during development and growth of mouse tissues.
Volume: 35
Issue: 8-9
Pages: 845-55
Publication
First Author: Gao Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling.
Volume: 107
Issue: 44
Pages: 18892-7
Publication  
First Author: Bernabei I
Year: 2023
Journal: Int J Mol Sci
Title: CD11b Deficiency Favors Cartilage Calcification via Increased Matrix Vesicles, Apoptosis, and Lysyl Oxidase Activity.
Volume: 24
Issue: 11
Publication
First Author: Chen JY
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Increased aortic stiffness and attenuated lysyl oxidase activity in obesity.
Volume: 33
Issue: 4
Pages: 839-46
Publication
First Author: Eliades A
Year: 2011
Journal: J Biol Chem
Title: Control of megakaryocyte expansion and bone marrow fibrosis by lysyl oxidase.
Volume: 286
Issue: 31
Pages: 27630-8
Publication
First Author: Pickup MW
Year: 2013
Journal: Cancer Res
Title: Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β-deficient mouse mammary carcinomas.
Volume: 73
Issue: 17
Pages: 5336-46
Publication
First Author: Lucero HA
Year: 2008
Journal: J Biol Chem
Title: Lysyl oxidase oxidizes cell membrane proteins and enhances the chemotactic response of vascular smooth muscle cells.
Volume: 283
Issue: 35
Pages: 24103-17
Publication
First Author: Pischon N
Year: 2009
Journal: Calcif Tissue Int
Title: Lysyl oxidase (lox) gene deficiency affects osteoblastic phenotype.
Volume: 85
Issue: 2
Pages: 119-26
Publication
First Author: Horiguchi M
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase.
Volume: 106
Issue: 45
Pages: 19029-34
Publication
First Author: Thomassin L
Year: 2005
Journal: J Biol Chem
Title: The Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibers.
Volume: 280
Issue: 52
Pages: 42848-55
Publication
First Author: Maruhashi T
Year: 2010
Journal: J Biol Chem
Title: Interaction between periostin and BMP-1 promotes proteolytic activation of lysyl oxidase.
Volume: 285
Issue: 17
Pages: 13294-303
Publication  
First Author: Busnadiego O
Year: 2015
Journal: J Mol Cell Cardiol
Title: Elevated expression levels of lysyl oxidases protect against aortic aneurysm progression in Marfan syndrome.
Volume: 85
Pages: 48-57
Publication
First Author: Kutchuk L
Year: 2015
Journal: Development
Title: Muscle composition is regulated by a Lox-TGFβ feedback loop.
Volume: 142
Issue: 5
Pages: 983-93
Publication
First Author: Mäki JM
Year: 2005
Journal: Am J Pathol
Title: Lysyl oxidase is essential for normal development and function of the respiratory system and for the integrity of elastic and collagen fibers in various tissues.
Volume: 167
Issue: 4
Pages: 927-36
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Contente S
Year: 1993
Journal: Genomics
Title: Structure of the mouse lysyl oxidase gene.
Volume: 16
Issue: 2
Pages: 395-400
Publication
First Author: de la Cueva A
Year: 2018
Journal: Carcinogenesis
Title: A polymorphism in the lysyl oxidase propeptide domain accelerates carcinogen-induced cancer.
Volume: 39
Issue: 7
Pages: 921-930
Publication
First Author: Sommer P
Year: 1993
Journal: Lab Invest
Title: Transient expression of lysyl oxidase by liver myofibroblasts in murine schistosomiasis.
Volume: 69
Issue: 4
Pages: 460-70
Publication
First Author: Contente S
Year: 1990
Journal: Science
Title: Expression of gene rrg is associated with reversion of NIH 3T3 transformed by LTR-c-H-ras.
Volume: 249
Issue: 4970
Pages: 796-8
Publication
First Author: Krzyzosiak WJ
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Isolation of genes specifically expressed in flat revertant cells derived from activated ras-transformed NIH 3T3 cells by treatment with azatyrosine.
Volume: 89
Issue: 11
Pages: 4879-83
Publication
First Author: Chang YS
Year: 1993
Journal: Cytogenet Cell Genet
Title: The mouse lysyl oxidase gene (Lox) resides on chromosome 18.
Volume: 63
Issue: 1
Pages: 47-9
Publication
First Author: Jourdan-Le Saux C
Year: 1994
Journal: Biochem Biophys Res Commun
Title: Lysyl oxidase cDNA of myofibroblast from mouse fibrotic liver.
Volume: 199
Issue: 2
Pages: 587-92
Publication
First Author: Dimaculangan DD
Year: 1994
Journal: Differentiation
Title: Retinoic acid prevents downregulation of ras recision gene/lysyl oxidase early in adipocyte differentiation.
Volume: 58
Issue: 1
Pages: 47-52
Publication
First Author: Tsuda T
Year: 2003
Journal: Anat Rec A Discov Mol Cell Evol Biol
Title: Prominent expression of lysyl oxidase during mouse embryonic cardiovascular development.
Volume: 270
Issue: 2
Pages: 93-6
Publication
First Author: Contente S
Year: 2009
Journal: Biochim Biophys Acta
Title: Tumor suppressive effect of lysyl oxidase proenzyme.
Volume: 1793
Issue: 7
Pages: 1272-8
GXD Expression    
Probe: MGI:7328495
Assay Type: RT-PCR
Annotation Date: 2022-08-09
Strength: Present
Sex: Female
Emaps: EMAPS:3590028
Stage: TS28
Assay Id: MGI:7328498
Age: postnatal adult
Image: 7
Specimen Label: Hif2a control
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7328495
Assay Type: RT-PCR
Annotation Date: 2022-08-09
Strength: Present
Sex: Female
Emaps: EMAPS:3590028
Stage: TS28
Assay Id: MGI:7328498
Age: postnatal adult
Image: 7
Specimen Label: Hif2a uKO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5576011
Assay Type: RT-PCR
Annotation Date: 2014-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1786622
Stage: TS22
Assay Id: MGI:5576054
Age: embryonic day 14.5
Image: 2
Specimen Label: wt
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5576011
Assay Type: RT-PCR
Annotation Date: 2014-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1786622
Stage: TS22
Assay Id: MGI:5576054
Age: embryonic day 14.5
Image: 2
Specimen Label: ko
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3693568
Assay Type: RT-PCR
Annotation Date: 2007-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1771322
Stage: TS22
Assay Id: MGI:3693757
Age: embryonic day 14.5
Specimen Label: wt
Detected: true
Specimen Num: 1
GXD Expression        
Probe: MGI:3693568
Assay Type: RT-PCR
Annotation Date: 2007-01-15
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1771322
Stage: TS22
Assay Id: MGI:3693757
Age: embryonic day 14.5
Specimen Label: Runx2-/-
Specimen Num: 2
GXD Expression      
Probe: MGI:6276111
Assay Type: RT-PCR
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1775521
Stage: TS21
Assay Id: MGI:6276200
Age: embryonic day 13.0
Specimen Label: Fetal 13
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6276111
Assay Type: RT-PCR
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1775522
Stage: TS22
Assay Id: MGI:6276200
Age: embryonic day 14.0
Specimen Label: Fetal 14
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5751979
Assay Type: RT-PCR
Annotation Date: 2016-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610518
Stage: TS18
Assay Id: MGI:5751981
Age: embryonic day 11.0
Specimen Label: E11
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5751979
Assay Type: RT-PCR
Annotation Date: 2016-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:5751981
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5751979
Assay Type: RT-PCR
Annotation Date: 2016-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610523
Stage: TS23
Assay Id: MGI:5751981
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6377079
Assay Type: Western blot
Annotation Date: 2019-11-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1860128
Stage: TS28
Assay Id: MGI:6377084
Age: postnatal week 4
Specimen Label: control
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7540926
Assay Type: RT-PCR
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768126
Stage: TS26
Assay Id: MGI:7540932
Age: embryonic day 18.5
Specimen Label: wt
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7540926
Assay Type: RT-PCR
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768126
Stage: TS26
Assay Id: MGI:7540932
Age: embryonic day 18.5
Specimen Label: LOX-/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6276111
Assay Type: RT-PCR
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881223
Stage: TS23
Assay Id: MGI:6276200
Age: embryonic day 15.0
Specimen Label: Fetal 15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6276111
Assay Type: RT-PCR
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881224
Stage: TS24
Assay Id: MGI:6276200
Age: embryonic day 16.0
Specimen Label: Fetal 16
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6276111
Assay Type: RT-PCR
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881225
Stage: TS25
Assay Id: MGI:6276200
Age: embryonic day 17.0
Specimen Label: Fetal 17
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6276111
Assay Type: RT-PCR
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881226
Stage: TS26
Assay Id: MGI:6276200
Age: embryonic day 18.0
Specimen Label: Fetal 18
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6276111
Assay Type: RT-PCR
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881227
Stage: TS27
Assay Id: MGI:6276200
Age: postnatal day 1
Specimen Label: Neonatal 1
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6276111
Assay Type: RT-PCR
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881228
Stage: TS28
Assay Id: MGI:6276200
Age: postnatal day 7
Specimen Label: Neonatal 7
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:6276111
Assay Type: RT-PCR
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881228
Stage: TS28
Assay Id: MGI:6276200
Age: postnatal day 14
Specimen Label: Neonatal 14
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:6276111
Assay Type: RT-PCR
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881228
Stage: TS28
Assay Id: MGI:6276200
Age: postnatal day 21
Specimen Label: Neonatal 21
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:6276111
Assay Type: RT-PCR
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881228
Stage: TS28
Assay Id: MGI:6276200
Age: postnatal day 28
Specimen Label: Neonatal 28
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:6276111
Assay Type: RT-PCR
Annotation Date: 2019-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881228
Stage: TS28
Assay Id: MGI:6276200
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:5309496
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5422864
Age: embryonic day 14.5
Specimen Label: MH3270; Specimen C4380
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309496
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716122
Stage: TS22
Assay Id: MGI:5422864
Age: embryonic day 14.5
Specimen Label: MH3270; Specimen C4380
Detected: false
Specimen Num: 1