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Search results 1 to 100 out of 361 for Lrg1

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
116844 | LRG1
Type: gene
Organism: human
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Gene
514663 | LRG1
Type: gene
Organism: cattle
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Gene
100858066 | LRG1
Type: gene
Organism: chicken
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Gene
693859 | LRG1
Type: gene
Organism: macaque, rhesus
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Gene
116406453 | lrg1
Type: gene
Organism: frog, western clawed
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Gene
367455 | Lrg1
Type: gene
Organism: rat
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Gene
611876 | LRG1
Type: gene
Organism: dog, domestic
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Gene
738488 | LRG1
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1924155 | Lrg1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:1767237
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2622022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825788
Age: embryonic day 14.5
Image: Additional file 4 Lrg1
Specimen Label: Additional file 4 Lrg1
Detected: true
Specimen Num: 1
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Publication
35590198 | J:339062
First Author: O'Connor MN
Year: 2021
Journal: Med
Title: LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency.
Volume: 2
Issue: 11
Pages: 1231-1252.e10
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Publication
34208965 | J:308333
 
First Author: Kwan YP
Year: 2021
Journal: Cancers (Basel)
Title: LRG1 Promotes Metastatic Dissemination of Melanoma through Regulating EGFR/STAT3 Signalling.
Volume: 13
Issue: 13
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Publication
30858225 | J:278766
First Author: Hong Q
Year: 2019
Journal: J Am Soc Nephrol
Title: LRG1 Promotes Diabetic Kidney Disease Progression by Enhancing TGF-β-Induced Angiogenesis.
Volume: 30
Issue: 4
Pages: 546-562
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Publication
35318338 | J:322560
First Author: Dritsoula A
Year: 2022
Journal: Sci Rep
Title: Angiopathic activity of LRG1 is induced by the IL-6/STAT3 pathway.
Volume: 12
Issue: 1
Pages: 4867
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Publication
23868260 | J:204744
First Author: Wang X
Year: 2013
Journal: Nature
Title: LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling.
Volume: 499
Issue: 7458
Pages: 306-11
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Publication
34730111 | J:321872
 
First Author: He S
Year: 2021
Journal: J Clin Invest
Title: LRG1 is an adipokine that mediates obesity-induced hepatosteatosis and insulin resistance.
Volume: 131
Issue: 24
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Publication
36346018 | J:337151
   
First Author: Choi CHJ
Year: 2022
Journal: Elife
Title: LRG1 is an adipokine that promotes insulin sensitivity and suppresses inflammation.
Volume: 11
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Publication
34516824 | J:344210
First Author: Singhal M
Year: 2021
Journal: Sci Transl Med
Title: Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis.
Volume: 13
Issue: 609
Pages: eabe6805
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Publication
31220542 | J:283015
 
First Author: Jin J
Year: 2019
Journal: Neuroscience
Title: LRG1 Promotes Apoptosis and Autophagy through the TGFβ-smad1/5 Signaling Pathway to Exacerbate Ischemia/Reperfusion Injury.
Volume: 413
Pages: 123-134
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Publication
34291056 | J:314435
 
First Author: Pang KT
Year: 2021
Journal: Front Cell Dev Biol
Title: Leucine-Rich α-2-Glycoprotein 1 Suppresses Endothelial Cell Activation Through ADAM10-Mediated Shedding of TNF-α Receptor.
Volume: 9
Pages: 706143
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Publication
32887674 | J:298977
First Author: Liu C
Year: 2020
Journal: Diabetes
Title: A Multifunctional Role of Leucine-Rich α-2-Glycoprotein 1 in Cutaneous Wound Healing Under Normal and Diabetic Conditions.
Volume: 69
Issue: 11
Pages: 2467-2480
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Publication
34774561 | J:333742
First Author: Hong Q
Year: 2022
Journal: Kidney Int
Title: Modulation of transforming growth factor-β-induced kidney fibrosis by leucine-rich ⍺-2 glycoprotein-1.
Volume: 101
Issue: 2
Pages: 299-314
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Publication
30515388 | J:295522
 
First Author: Haku S
Year: 2018
Journal: Biomed Res Int
Title: Early Enhanced Leucine-Rich α-2-Glycoprotein-1 Expression in Glomerular Endothelial Cells of Type 2 Diabetic Nephropathy Model Mice.
Volume: 2018
Pages: 2817045
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Protein Coding Gene
MGP_CAROLIEiJ_G0021766 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0023914 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023873 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023843 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023875 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023638 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1924155 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024319 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023121 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023615 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0023743 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0023709 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023823 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0023736 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024364 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022866 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023185 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0020755 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022678 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
12223515 | J:78905
First Author: O'Donnell LC
Year: 2002
Journal: J Leukoc Biol
Title: Molecular characterization and expression analysis of leucine-rich alpha2-glycoprotein, a novel marker of granulocytic differentiation.
Volume: 72
Issue: 3
Pages: 478-85
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Publication
25826092 | J:263152
First Author: Takemoto N
Year: 2015
Journal: Oncotarget
Title: Leucine-rich α-2-glycoprotein promotes TGFβ1-mediated growth suppression in the Lewis lung carcinoma cell lines.
Volume: 6
Issue: 13
Pages: 11009-22
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Publication
26678356 | J:252575
First Author: Kumagai S
Year: 2016
Journal: Cardiovasc Res
Title: Myeloid cell-derived LRG attenuates adverse cardiac remodelling after myocardial infarction.
Volume: 109
Issue: 2
Pages: 272-82
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Publication
24058569 | J:206041
First Author: Miyajima M
Year: 2013
Journal: PLoS One
Title: Leucine-rich α2-glycoprotein is a novel biomarker of neurodegenerative disease in human cerebrospinal fluid and causes neurodegeneration in mouse cerebral cortex.
Volume: 8
Issue: 9
Pages: e74453
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Publication
28917663 | J:256717
 
First Author: Akiba C
Year: 2017
Journal: Neurobiol Aging
Title: Leucine-rich α2-glycoprotein overexpression in the brain contributes to memory impairment.
Volume: 60
Pages: 11-19
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Publication
19324010 | J:148353
First Author: Shirai R
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Up-regulation of the expression of leucine-rich alpha(2)-glycoprotein in hepatocytes by the mediators of acute-phase response.
Volume: 382
Issue: 4
Pages: 776-9
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Publication
33648938 | J:303896
First Author: Nakajima H
Year: 2021
Journal: J Immunol
Title: The Skin-Liver Axis Modulates the Psoriasiform Phenotype and Involves Leucine-Rich α-2 Glycoprotein.
Volume: 206
Issue: 7
Pages: 1469-1477
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Publication
26935556 | J:234421
First Author: Alsina FC
Year: 2016
Journal: EMBO Rep
Title: Lrig1 is a cell-intrinsic modulator of hippocampal dendrite complexity and BDNF signaling.
Volume: 17
Issue: 4
Pages: 601-16
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Publication
18492766 | J:137608
First Author: Wu Y
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Wdnm1-like, a new adipokine with a role in MMP-2 activation.
Volume: 295
Issue: 1
Pages: E205-15
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Publication
22509320 | J:307941
First Author: Zuo B
Year: 2012
Journal: PLoS One
Title: Analysis of microsatellite polymorphism in inbred knockout mice.
Volume: 7
Issue: 4
Pages: e34555
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Publication
15760467 | J:99477
 
First Author: Brown AC
Year: 2005
Journal: BMC Genet
Title: Searching QTL by gene expression: analysis of diabesity.
Volume: 6
Pages: 12
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Publication
23012479 | J:190322
First Author: Archambaud C
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Impact of lactobacilli on orally acquired listeriosis.
Volume: 109
Issue: 41
Pages: 16684-9
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Publication
27480124 | J:237787
First Author: Liu X
Year: 2016
Journal: BMC Immunol
Title: Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Volume: 17
Issue: 1
Pages: 25
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Lrg1<em1Smoc> | MGI:7290865
Name: leucine-rich alpha-2-glycoprotein 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6429121 | C57BL/6J-Lrg1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
8065929 | -
First Author: Müller L
Year: 1994
Journal: Nucleic Acids Res
Title: LRG1 is expressed during sporulation in Saccharomyces cerevisiae and contains motifs similar to LIM and rho/racGAP domains.
Volume: 22
Issue: 15
Pages: 3151-4
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Publication
38354758 | J:345719
First Author: Tsuruta H
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Fructose overconsumption accelerates renal dysfunction with aberrant glomerular endothelial-mesangial cell interactions in db/db mice.
Volume: 1870
Issue: 4
Pages: 167074
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Publication
32387619 | J:331818
 
First Author: Li W
Year: 2020
Journal: Exp Eye Res
Title: Leucine-rich α-2-glycoprotein-1 promotes diabetic corneal epithelial wound healing and nerve regeneration via regulation of matrix metalloproteinases.
Volume: 196
Pages: 108060
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Protein
Q91XC0
Organism: Mus musculus/domesticus
Length: 547  
Fragment?: false
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Protein
P63254
Organism: Mus musculus/domesticus
Length: 77  
Fragment?: false
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Protein
P25801
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: false
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Protein
Q8BGB5
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: false
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Protein
Q924W9
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: false
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Protein
Q71FD7
Organism: Mus musculus/domesticus
Length: 375  
Fragment?: false
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Protein
Q91XD2
Organism: Mus musculus/domesticus
Length: 341  
Fragment?: false
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Protein
Q9QXD8
Organism: Mus musculus/domesticus
Length: 668  
Fragment?: false
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Protein
P97314
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: false
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Protein
P50462
Organism: Mus musculus/domesticus
Length: 194  
Fragment?: false
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Protein
P97315
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom