Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6739862 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-17 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:2800724 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6740180 |
Age: |
embryonic day 16.5 |
Image: |
5A Lrp1 Six2Cre Brg1flx/flx |
Note: |
Authors report 87% reduction in proximal tubules. |
Specimen Label: |
5A Lrp1 Six2Cre Brg1flx/flx |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6739862 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-08-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:2800324 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6740180 |
Age: |
embryonic day 16.5 |
Image: |
5A Lrp1 Brg1flx/flx |
Note: |
Formation of proximal tubules readily apparent. |
Specimen Label: |
5A Lrp1 Brg1flx/flx |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boel NM |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
LRP1 is required for novobiocin-mediated fibronectin turnover. |
Volume: |
8 |
Issue: |
1 |
Pages: |
11438 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kanai Y |
Year: |
2014 |
Journal: |
J Cell Biol |
Title: |
KIF13B enhances the endocytosis of LRP1 by recruiting LRP1 to caveolae. |
Volume: |
204 |
Issue: |
3 |
Pages: |
395-408 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hamlin AN |
Year: |
2016 |
Journal: |
J Biol Chem |
Title: |
LRP1 Protein Deficiency Exacerbates Palmitate-induced Steatosis and Toxicity in Hepatocytes. |
Volume: |
291 |
Issue: |
32 |
Pages: |
16610-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Storck SE |
Year: |
2016 |
Journal: |
J Clin Invest |
Title: |
Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier. |
Volume: |
126 |
Issue: |
1 |
Pages: |
123-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pflanzner T |
Year: |
2011 |
Journal: |
Neurobiol Aging |
Title: |
LRP1 mediates bidirectional transcytosis of amyloid-β across the blood-brain barrier. |
Volume: |
32 |
Issue: |
12 |
Pages: |
2323.e1-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu CC |
Year: |
2017 |
Journal: |
J Neurosci |
Title: |
Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition. |
Volume: |
37 |
Issue: |
15 |
Pages: |
4023-4031 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gaultier A |
Year: |
2010 |
Journal: |
Matrix Biol |
Title: |
LRP1 regulates remodeling of the extracellular matrix by fibroblasts. |
Volume: |
29 |
Issue: |
1 |
Pages: |
22-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Reekmans SM |
Year: |
2010 |
Journal: |
Cell Mol Life Sci |
Title: |
Inactivation of the proximal NPXY motif impairs early steps in LRP1 biosynthesis. |
Volume: |
67 |
Issue: |
1 |
Pages: |
135-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rastegarlari G |
Year: |
2012 |
Journal: |
Blood |
Title: |
Macrophage LRP1 contributes to the clearance of von Willebrand factor. |
Volume: |
119 |
Issue: |
9 |
Pages: |
2126-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou L |
Year: |
2009 |
Journal: |
PLoS One |
Title: |
LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol export. |
Volume: |
4 |
Issue: |
8 |
Pages: |
e6853 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lehti K |
Year: |
2009 |
Journal: |
J Cell Sci |
Title: |
MT1-MMP promotes vascular smooth muscle dedifferentiation through LRP1 processing. |
Volume: |
122 |
Issue: |
Pt 1 |
Pages: |
126-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen K |
Year: |
2022 |
Journal: |
Mol Neurodegener |
Title: |
LRP1 is a neuronal receptor for α-synuclein uptake and spread. |
Volume: |
17 |
Issue: |
1 |
Pages: |
57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schwarz MM |
Year: |
2023 |
Journal: |
Sci Adv |
Title: |
Lrp1 is essential for lethal Rift Valley fever hepatic disease in mice. |
Volume: |
9 |
Issue: |
28 |
Pages: |
eadh2264 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ganaie SS |
Year: |
2021 |
Journal: |
Cell |
Title: |
Lrp1 is a host entry factor for Rift Valley fever virus. |
Volume: |
184 |
Issue: |
20 |
Pages: |
5163-5178.e24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xian X |
Year: |
2017 |
Journal: |
Elife |
Title: |
LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis. |
Volume: |
6 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Liu CC |
Year: |
2015 |
Journal: |
J Neurosci |
Title: |
Neuronal LRP1 regulates glucose metabolism and insulin signaling in the brain. |
Volume: |
35 |
Issue: |
14 |
Pages: |
5851-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Capurro MI |
Year: |
2012 |
Journal: |
J Cell Sci |
Title: |
LRP1 mediates Hedgehog-induced endocytosis of the GPC3-Hedgehog complex. |
Volume: |
125 |
Issue: |
Pt 14 |
Pages: |
3380-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mao H |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ. |
Volume: |
8 |
|
Pages: |
14960 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kohara Y |
Year: |
2020 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Knockdown of Lrp1 in RAW264 cells inhibits osteoclast differentiation and osteoclast-osteoblast interactions in vitro. |
Volume: |
523 |
Issue: |
4 |
Pages: |
961-965 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakajima C |
Year: |
2014 |
Journal: |
Development |
Title: |
The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development. |
Volume: |
141 |
Issue: |
23 |
Pages: |
4513-25 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6190739 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Lrp1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6190739 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Lrp1 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6190739 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Lrp1 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6190739 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Lrp1 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190739 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Lrp1 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190739 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Lrp1 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190739 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Lrp1 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vi L |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice. |
Volume: |
9 |
Issue: |
1 |
Pages: |
5191 |
|
•
•
•
•
•
|
Publication |
First Author: |
May P |
Year: |
2004 |
Journal: |
Mol Cell Biol |
Title: |
Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice. |
Volume: |
24 |
Issue: |
20 |
Pages: |
8872-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Orita S |
Year: |
2013 |
Journal: |
J Neurosci |
Title: |
Schwann cell LRP1 regulates remak bundle ultrastructure and axonal interactions to prevent neuropathic pain. |
Volume: |
33 |
Issue: |
13 |
Pages: |
5590-602 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schnieder J |
Year: |
2020 |
Journal: |
Matrix Biol |
Title: |
Loss of LRP1 promotes acquisition of contractile-myofibroblast phenotype and release of active TGF-β1 from ECM stores. |
Volume: |
88 |
|
Pages: |
69-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nichols CE |
Year: |
2021 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Lrp1 Regulation of Pulmonary Function. Follow-Up of Human GWAS in Mice. |
Volume: |
64 |
Issue: |
3 |
Pages: |
368-378 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jaeschke A |
Year: |
2020 |
Journal: |
J Lipid Res |
Title: |
Mutation in the distal NPxY motif of LRP1 alleviates dietary cholesterol-induced dyslipidemia and tissue inflammation. |
Volume: |
62 |
|
Pages: |
100012 |
|
•
•
•
•
•
|
Publication |
First Author: |
Konaniah ES |
Year: |
2017 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Deficiency of LRP1 in Mature Adipocytes Promotes Diet-Induced Inflammation and Atherosclerosis-Brief Report. |
Volume: |
37 |
Issue: |
6 |
Pages: |
1046-1049 |
|
•
•
•
•
•
|
Publication |
First Author: |
Herr UM |
Year: |
2017 |
Journal: |
Front Mol Neurosci |
Title: |
LRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric State. |
Volume: |
10 |
|
Pages: |
118 |
|
•
•
•
•
•
|
Publication |
First Author: |
Garcia-Arcos I |
Year: |
2022 |
Journal: |
J Lipid Res |
Title: |
LRP1 loss in airway epithelium exacerbates smoke-induced oxidative damage and airway remodeling. |
Volume: |
63 |
Issue: |
4 |
Pages: |
100185 |
|
•
•
•
•
•
|
Publication |
First Author: |
He L |
Year: |
2023 |
Journal: |
Cell Commun Signal |
Title: |
FUT2 inhibits the EMT and metastasis of colorectal cancer by increasing LRP1 fucosylation. |
Volume: |
21 |
Issue: |
1 |
Pages: |
63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Terrand J |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
LRP1 controls intracellular cholesterol storage and fatty acid synthesis through modulation of Wnt signaling. |
Volume: |
284 |
Issue: |
1 |
Pages: |
381-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Q |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000575 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mao H |
Year: |
2016 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
LRP1 Regulates Retinal Angiogenesis by Inhibiting PARP-1 Activity and Endothelial Cell Proliferation. |
Volume: |
36 |
Issue: |
2 |
Pages: |
350-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brifault C |
Year: |
2019 |
Journal: |
Glia |
Title: |
LRP1 deficiency in microglia blocks neuro-inflammation in the spinal dorsal horn and neuropathic pain processing. |
Volume: |
67 |
Issue: |
6 |
Pages: |
1210-1224 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oue H |
Year: |
2023 |
Journal: |
JCI Insight |
Title: |
LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4. |
Volume: |
8 |
Issue: |
7 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kanekiyo T |
Year: |
2012 |
Journal: |
J Neurosci |
Title: |
LRP1 in brain vascular smooth muscle cells mediates local clearance of Alzheimer's amyloid-β. |
Volume: |
32 |
Issue: |
46 |
Pages: |
16458-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shackleton B |
Year: |
2016 |
Journal: |
Fluids Barriers CNS |
Title: |
Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding. |
Volume: |
13 |
Issue: |
1 |
Pages: |
14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gordts PL |
Year: |
2009 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Inactivation of the LRP1 intracellular NPxYxxL motif in LDLR-deficient mice enhances postprandial dyslipidemia and atherosclerosis. |
Volume: |
29 |
Issue: |
9 |
Pages: |
1258-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Muratoglu SC |
Year: |
2013 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
LRP1 protects the vasculature by regulating levels of connective tissue growth factor and HtrA1. |
Volume: |
33 |
Issue: |
9 |
Pages: |
2137-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roebroek AJ |
Year: |
2006 |
Journal: |
Mol Cell Biol |
Title: |
Mutant Lrp1 knock-in mice generated by recombinase-mediated cassette exchange reveal differential importance of the NPXY motifs in the intracellular domain of LRP1 for normal fetal development. |
Volume: |
26 |
Issue: |
2 |
Pages: |
605-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maier W |
Year: |
2013 |
Journal: |
Mol Neurodegener |
Title: |
LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype. |
Volume: |
8 |
|
Pages: |
25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin JI |
Year: |
2020 |
Journal: |
Commun Biol |
Title: |
Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening. |
Volume: |
3 |
Issue: |
1 |
Pages: |
312 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Q |
Year: |
2010 |
Journal: |
J Neurosci |
Title: |
Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. |
Volume: |
30 |
Issue: |
50 |
Pages: |
17068-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Velmurugan GV |
Year: |
2023 |
Journal: |
Cells |
Title: |
LRP1 Deficiency Promotes Mitostasis in Response to Oxidative Stress: Implications for Mitochondrial Targeting after Traumatic Brain Injury. |
Volume: |
12 |
Issue: |
10 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou L |
Year: |
2009 |
Journal: |
PLoS One |
Title: |
LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation. |
Volume: |
4 |
Issue: |
9 |
Pages: |
e6922 |
|
•
•
•
•
•
|
Publication |
First Author: |
Muratoglu SC |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Macrophage LRP1 suppresses neo-intima formation during vascular remodeling by modulating the TGF-β signaling pathway. |
Volume: |
6 |
Issue: |
12 |
Pages: |
e28846 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin JP |
Year: |
2017 |
Journal: |
Elife |
Title: |
LRP1 regulates peroxisome biogenesis and cholesterol homeostasis in oligodendrocytes and is required for proper CNS myelin development and repair. |
Volume: |
6 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Calvier L |
Year: |
2019 |
Journal: |
Circ Res |
Title: |
LRP1 Deficiency in Vascular SMC Leads to Pulmonary Arterial Hypertension That Is Reversed by PPARγ Activation. |
Volume: |
124 |
Issue: |
12 |
Pages: |
1778-1785 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boucher P |
Year: |
2007 |
Journal: |
PLoS One |
Title: |
LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome. |
Volume: |
2 |
Issue: |
5 |
Pages: |
e448 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jedrychowski MP |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
Proteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signaling. |
Volume: |
285 |
Issue: |
1 |
Pages: |
104-14 |
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Publication |
First Author: |
Wohner N |
Year: |
2015 |
Journal: |
J Thromb Haemost |
Title: |
Shear stress-independent binding of von Willebrand factor-type 2B mutants p.R1306Q & p.V1316M to LRP1 explains their increased clearance. |
Volume: |
13 |
Issue: |
5 |
Pages: |
815-20 |
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Publication |
First Author: |
Van Gool B |
Year: |
2019 |
Journal: |
Mol Neurobiol |
Title: |
LRP1 Has a Predominant Role in Production over Clearance of Aβ in a Mouse Model of Alzheimer's Disease. |
Volume: |
56 |
Issue: |
10 |
Pages: |
7234-7245 |
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Publication |
First Author: |
Fu T |
Year: |
2017 |
Journal: |
Biochim Biophys Acta |
Title: |
APP, APLP2 and LRP1 interact with PCSK9 but are not required for PCSK9-mediated degradation of the LDLR in vivo. |
Volume: |
1862 |
Issue: |
9 |
Pages: |
883-889 |
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Publication |
First Author: |
Romeo R |
Year: |
2020 |
Journal: |
Front Cell Neurosci |
Title: |
Deletion of LRP1 From Astrocytes Modifies Neuronal Network Activity in an in vitro Model of the Tripartite Synapse. |
Volume: |
14 |
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Pages: |
567253 |
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Publication |
First Author: |
Yan W |
Year: |
2022 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Heterozygous LRP1 deficiency causes developmental dysplasia of the hip by impairing triradiate chondrocytes differentiation due to inhibition of autophagy. |
Volume: |
119 |
Issue: |
37 |
Pages: |
e2203557119 |
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Publication |
First Author: |
Au DT |
Year: |
2018 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Regulates Smooth Muscle Contractility by Modulating Ca2+ Signaling and Expression of Cytoskeleton-Related Proteins. |
Volume: |
38 |
Issue: |
11 |
Pages: |
2651-2664 |
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Publication |
First Author: |
Guo YX |
Year: |
2016 |
Journal: |
Neuroscience |
Title: |
1,25-Dihydroxyvitamin D3 regulates expression of LRP1 and RAGE in vitro and in vivo, enhancing Aβ1-40 brain-to-blood efflux and peripheral uptake transport. |
Volume: |
322 |
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Pages: |
28-38 |
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Publication |
First Author: |
Mueller PA |
Year: |
2022 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Macrophage LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Is Required for the Effect of CD47 Blockade on Efferocytosis and Atherogenesis-Brief Report. |
Volume: |
42 |
Issue: |
1 |
Pages: |
e1-e9 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
401
 |
Fragment?: |
true |
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Publication |
First Author: |
Mark PR |
Year: |
2022 |
Journal: |
Cold Spring Harb Mol Case Stud |
Title: |
Autosomal recessive LRP1-related syndrome featuring cardiopulmonary dysfunction, bone dysmorphology, and corneal clouding. |
Volume: |
8 |
Issue: |
6 |
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Publication |
First Author: |
Ding Y |
Year: |
2016 |
Journal: |
EBioMedicine |
Title: |
Low-Density Lipoprotein Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and Hepatic Steatosis. |
Volume: |
7 |
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Pages: |
135-45 |
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Publication |
First Author: |
Bang YJ |
Year: |
2021 |
Journal: |
Science |
Title: |
Serum amyloid A delivers retinol to intestinal myeloid cells to promote adaptive immunity. |
Volume: |
373 |
Issue: |
6561 |
Pages: |
eabf9232 |
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Publication |
First Author: |
Zurhove K |
Year: |
2008 |
Journal: |
Sci Signal |
Title: |
Gamma-secretase limits the inflammatory response through the processing of LRP1. |
Volume: |
1 |
Issue: |
47 |
Pages: |
ra15 |
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Publication |
First Author: |
Basford JE |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
Hepatic deficiency of low density lipoprotein receptor-related protein-1 reduces high density lipoprotein secretion and plasma levels in mice. |
Volume: |
286 |
Issue: |
15 |
Pages: |
13079-87 |
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Publication |
First Author: |
Hamlin AN |
Year: |
2018 |
Journal: |
J Biol Chem |
Title: |
Low-density lipoprotein receptor-related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression. |
Volume: |
293 |
Issue: |
25 |
Pages: |
9674-9684 |
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Publication |
First Author: |
Tachibana M |
Year: |
2016 |
Journal: |
Exp Neurol |
Title: |
Rescuing effects of RXR agonist bexarotene on aging-related synapse loss depend on neuronal LRP1. |
Volume: |
277 |
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Pages: |
1-9 |
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Publication |
First Author: |
Xu G |
Year: |
2012 |
Journal: |
Alzheimers Res Ther |
Title: |
Reduction of low-density lipoprotein receptor-related protein (LRP1) in hippocampal neurons does not proportionately reduce, or otherwise alter, amyloid deposition in APPswe/PS1dE9 transgenic mice. |
Volume: |
4 |
Issue: |
2 |
Pages: |
12 |
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•
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Publication |
First Author: |
Poplawski G |
Year: |
2018 |
Journal: |
Glia |
Title: |
Schwann cells regulate sensory neuron gene expression before and after peripheral nerve injury. |
Volume: |
66 |
Issue: |
8 |
Pages: |
1577-1590 |
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Publication |
First Author: |
Basford JE |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Smooth muscle LDL receptor-related protein-1 deletion induces aortic insufficiency and promotes vascular cardiomyopathy in mice. |
Volume: |
8 |
Issue: |
11 |
Pages: |
e82026 |
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Publication |
First Author: |
Benitez-Amaro A |
Year: |
2020 |
Journal: |
Metabolism |
Title: |
Low-density lipoprotein receptor-related protein 1 deficiency in cardiomyocytes reduces susceptibility to insulin resistance and obesity. |
Volume: |
106 |
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Pages: |
154191 |
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Publication |
First Author: |
Hofmann SM |
Year: |
2007 |
Journal: |
J Clin Invest |
Title: |
Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice. |
Volume: |
117 |
Issue: |
11 |
Pages: |
3271-82 |
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Publication |
First Author: |
Gaultier A |
Year: |
2009 |
Journal: |
J Cell Sci |
Title: |
Low-density lipoprotein receptor-related protein 1 is an essential receptor for myelin phagocytosis. |
Volume: |
122 |
Issue: |
Pt 8 |
Pages: |
1155-62 |
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Publication |
First Author: |
Fernandez-Castaneda A |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
Identification of the low density lipoprotein (LDL) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris. |
Volume: |
288 |
Issue: |
7 |
Pages: |
4538-48 |
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Publication |
First Author: |
Chen J |
Year: |
2020 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
sLRP1 (Soluble Low-Density Lipoprotein Receptor-Related Protein 1): A Novel Biomarker for P2Y12 (P2Y Purinoceptor 12) Receptor Expression in Atherosclerotic Plaques. |
Volume: |
40 |
Issue: |
6 |
Pages: |
e166-e179 |
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Publication |
First Author: |
Basford JE |
Year: |
2009 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Smooth muscle LDL receptor-related protein-1 inactivation reduces vascular reactivity and promotes injury-induced neointima formation. |
Volume: |
29 |
Issue: |
11 |
Pages: |
1772-8 |
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Publication |
First Author: |
Pi X |
Year: |
2012 |
Journal: |
Circ Res |
Title: |
LRP1-dependent endocytic mechanism governs the signaling output of the bmp system in endothelial cells and in angiogenesis. |
Volume: |
111 |
Issue: |
5 |
Pages: |
564-74 |
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Publication |
First Author: |
Boucher P |
Year: |
2003 |
Journal: |
Science |
Title: |
LRP: role in vascular wall integrity and protection from atherosclerosis. |
Volume: |
300 |
Issue: |
5617 |
Pages: |
329-32 |
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Publication |
First Author: |
Lee J |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells. |
Volume: |
14 |
Issue: |
1 |
Pages: |
8463 |
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Publication |
First Author: |
Strickland DK |
Year: |
2014 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Low-density lipoprotein receptor-related protein-1: role in the regulation of vascular integrity. |
Volume: |
34 |
Issue: |
3 |
Pages: |
487-98 |
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Publication |
First Author: |
Yamamoto K |
Year: |
2022 |
Journal: |
Matrix Biol |
Title: |
A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage. |
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Publication |
First Author: |
Davis FM |
Year: |
2015 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Smooth muscle cell deletion of low-density lipoprotein receptor-related protein 1 augments angiotensin II-induced superior mesenteric arterial and ascending aortic aneurysms. |
Volume: |
35 |
Issue: |
1 |
Pages: |
155-62 |
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