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Search results 1 to 100 out of 695 for Lrp2

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Christ A
Year: 2012
Journal: Dev Cell
Title: LRP2 is an auxiliary SHH receptor required to condition the forebrain ventral midline for inductive signals.
Volume: 22
Issue: 2
Pages: 268-78
Gene
Type: gene
Organism: Homo sapiens
Allele
Name: low density lipoprotein receptor-related protein 2; targeted mutation 2, Thomas E Willnow
Allele Type: Targeted
Attribute String: Recombinase
Publication categories: ProxyCollection
Genotype
Symbol: Lrp2/Lrp2<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Oh SJ
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Progesterone induces expression of Lrp2 in the murine uterus.
Volume: 441
Issue: 1
Pages: 175-9
Publication
First Author: Kur E
Year: 2014
Journal: J Cell Sci
Title: LRP2 mediates folate uptake in the developing neural tube.
Volume: 127
Issue: Pt 10
Pages: 2261-8
Publication
First Author: Baardman ME
Year: 2016
Journal: Dis Model Mech
Title: Common arterial trunk and ventricular non-compaction in Lrp2 knockout mice indicate a crucial role of LRP2 in cardiac development.
Volume: 9
Issue: 4
Pages: 413-25
Publication
First Author: Gajera CR
Year: 2010
Journal: J Cell Sci
Title: LRP2 in ependymal cells regulates BMP signaling in the adult neurogenic niche.
Volume: 123
Issue: Pt 11
Pages: 1922-30
Publication
First Author: Gerbe F
Year: 2008
Journal: Dev Biol
Title: Dynamic expression of Lrp2 pathway members reveals progressive epithelial differentiation of primitive endoderm in mouse blastocyst.
Volume: 313
Issue: 2
Pages: 594-602
Publication
First Author: Christ A
Year: 2015
Journal: Dev Cell
Title: LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli.
Volume: 35
Issue: 1
Pages: 36-48
Publication
First Author: Cases O
Year: 2015
Journal: PLoS One
Title: Foxg1-Cre Mediated Lrp2 Inactivation in the Developing Mouse Neural Retina, Ciliary and Retinal Pigment Epithelia Models Congenital High Myopia.
Volume: 10
Issue: 6
Pages: e0129518
Publication    
First Author: Hammad SM
Year: 2000
Journal: GenBank Submission
Title: Mus musculus low density lipoprotein receptor-related protein 2 LRP2 (Lrp2) mRNA, partial cds
Pages: AF197160
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Publication
First Author: Petersen HH
Year: 2003
Journal: J Cell Sci
Title: Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule.
Volume: 116
Issue: Pt 3
Pages: 453-61
Publication
First Author: Christ A
Year: 2010
Journal: Kidney Int
Title: The soluble intracellular domain of megalin does not affect renal proximal tubular function in vivo.
Volume: 78
Issue: 5
Pages: 473-7
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Storm T
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Selective Ablation of Megalin in the Retinal Pigment Epithelium Results in Megaophthalmos, Macromelanosome Formation and Severe Retina Degeneration.
Volume: 60
Issue: 1
Pages: 322-330
Publication
First Author: Cases O
Year: 2017
Journal: Biochim Biophys Acta
Title: Impaired vitreous composition and retinal pigment epithelium function in the FoxG1::LRP2 myopic mice.
Volume: 1863
Issue: 6
Pages: 1242-1254
Publication
First Author: Lighthouse JK
Year: 2011
Journal: Dev Dyn
Title: MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.
Volume: 240
Issue: 3
Pages: 577-88
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Nykjaer A
Year: 1999
Journal: Cell
Title: An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3.
Volume: 96
Issue: 4
Pages: 507-15
Publication
First Author: Gburek J
Year: 2003
Journal: Am J Physiol Renal Physiol
Title: Renal uptake of myoglobin is mediated by the endocytic receptors megalin and cubilin.
Volume: 285
Issue: 3
Pages: F451-8
Publication
First Author: Hammes A
Year: 2005
Journal: Cell
Title: Role of endocytosis in cellular uptake of sex steroids.
Volume: 122
Issue: 5
Pages: 751-62
Publication
First Author: Gonzalez-Villalobos R
Year: 2006
Journal: Am J Physiol Renal Physiol
Title: Megalin binds and internalizes angiotensin-(1-7).
Volume: 290
Issue: 5
Pages: F1270-5
Publication
First Author: K├Ânig O
Year: 2008
Journal: FASEB J
Title: Estrogen and the inner ear: megalin knockout mice suffer progressive hearing loss.
Volume: 22
Issue: 2
Pages: 410-7
Publication
First Author: Leheste JR
Year: 2003
Journal: FASEB J
Title: Hypocalcemia and osteopathy in mice with kidney-specific megalin gene defect.
Volume: 17
Issue: 2
Pages: 247-9
Publication
First Author: Theilig F
Year: 2007
Journal: J Am Soc Nephrol
Title: Abrogation of protein uptake through megalin-deficient proximal tubules does not safeguard against tubulointerstitial injury.
Volume: 18
Issue: 6
Pages: 1824-34
Publication
First Author: Bachmann S
Year: 2004
Journal: J Am Soc Nephrol
Title: Kidney-specific inactivation of the megalin gene impairs trafficking of renal inorganic sodium phosphate cotransporter (NaPi-IIa).
Volume: 15
Issue: 4
Pages: 892-900
Publication
First Author: Raila J
Year: 2005
Journal: J Nutr
Title: Megalin-mediated reuptake of retinol in the kidneys of mice is essential for vitamin A homeostasis.
Volume: 135
Issue: 11
Pages: 2512-6
Publication
First Author: Motoyoshi Y
Year: 2008
Journal: Kidney Int
Title: Megalin contributes to the early injury of proximal tubule cells during nonselective proteinuria.
Volume: 74
Issue: 10
Pages: 1262-9
Publication
First Author: Willnow TE
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Defective forebrain development in mice lacking gp330/megalin.
Volume: 93
Issue: 16
Pages: 8460-4
Publication
First Author: Leheste JR
Year: 1999
Journal: Am J Pathol
Title: Megalin knockout mice as an animal model of low molecular weight proteinuria.
Volume: 155
Issue: 4
Pages: 1361-70
Publication
First Author: Christensen EI
Year: 1999
Journal: J Am Soc Nephrol
Title: Evidence for an essential role of megalin in transepithelial transport of retinol.
Volume: 10
Issue: 4
Pages: 685-95
Publication
First Author: Birn H
Year: 2002
Journal: Am J Physiol Renal Physiol
Title: Megalin is essential for renal proximal tubule reabsorption and accumulation of transcobalamin-B(12).
Volume: 282
Issue: 3
Pages: F408-16
Publication
First Author: Moestrup SK
Year: 1998
Journal: J Clin Invest
Title: beta2-glycoprotein-I (apolipoprotein H) and beta2-glycoprotein-I-phospholipid complex harbor a recognition site for the endocytic receptor megalin.
Volume: 102
Issue: 5
Pages: 902-9
Publication
First Author: Birn H
Year: 2000
Journal: J Clin Invest
Title: Cubilin is an albumin binding protein important for renal tubular albumin reabsorption.
Volume: 105
Issue: 10
Pages: 1353-61
Publication
First Author: Lisi S
Year: 2005
Journal: Mol Cell Endocrinol
Title: Thyroid dysfunction in megalin deficient mice.
Volume: 236
Issue: 1-2
Pages: 43-7
Publication
First Author: Shrestha S
Year: 2018
Journal: Sci Rep
Title: Circulating FABP4 is eliminated by the kidney via glomerular filtration followed by megalin-mediated reabsorption.
Volume: 8
Issue: 1
Pages: 16451
Publication
First Author: Chiu-Ugalde J
Year: 2010
Journal: Biochem J
Title: Mutation of megalin leads to urinary loss of selenoprotein P and selenium deficiency in serum, liver, kidneys and brain.
Volume: 431
Issue: 1
Pages: 103-11
Publication
First Author: Leshchiner I
Year: 2012
Journal: Genome Res
Title: Mutation mapping and identification by whole-genome sequencing.
Volume: 22
Issue: 8
Pages: 1541-8
Publication
First Author: Gueth-Hallonet C
Year: 1994
Journal: Development
Title: Gp330 is specifically expressed in outer cells during epithelial differentiation in the preimplantation mouse embryo.
Volume: 120
Issue: 11
Pages: 3289-99
Publication
First Author: Chowdhary BP
Year: 1995
Journal: Cytogenet Cell Genet
Title: In situ hybridization mapping of a 500-kDa calcium-sensing protein gene (LRP2) to human chromosome region 2q31-->q32.1 and porcine chromosome region 15q22-->q24.
Volume: 71
Issue: 2
Pages: 120-3
Publication
First Author: Niemeier A
Year: 1999
Journal: Arterioscler Thromb Vasc Biol
Title: Identification of megalin/gp330 as a receptor for lipoprotein(a) in vitro.
Volume: 19
Issue: 3
Pages: 552-61
Publication
First Author: De S
Year: 2017
Journal: Diabetes
Title: Exocytosis-Mediated Urinary Full-Length Megalin Excretion Is Linked With the Pathogenesis of Diabetic Nephropathy.
Volume: 66
Issue: 5
Pages: 1391-1404
GXD Expression      
Probe: MGI:5529487
Assay Type: RT-PCR
Annotation Date: 2014-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Stage: TS24
Assay Id: MGI:5529492
Age: embryonic day 16.5
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5529487
Assay Type: RT-PCR
Annotation Date: 2014-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Stage: TS24
Assay Id: MGI:5529492
Age: embryonic day 16.5
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5529487
Assay Type: RT-PCR
Annotation Date: 2014-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:5529492
Age: embryonic day 14.5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5529487
Assay Type: RT-PCR
Annotation Date: 2014-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:5529492
Age: embryonic day 14.5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5529487
Assay Type: RT-PCR
Annotation Date: 2014-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:5529492
Age: embryonic day 11.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5529487
Assay Type: RT-PCR
Annotation Date: 2014-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:5529492
Age: embryonic day 11.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5529487
Assay Type: RT-PCR
Annotation Date: 2014-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5529492
Age: embryonic day 9.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5529487
Assay Type: RT-PCR
Annotation Date: 2014-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5529492
Age: embryonic day 9.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6189052
Assay Type: RT-PCR
Annotation Date: 2018-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360356
Stage: TS06
Assay Id: MGI:6189087
Age: embryonic day 4.5
Image: 1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6189052
Assay Type: RT-PCR
Annotation Date: 2018-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Stage: TS04
Assay Id: MGI:6189087
Age: embryonic day 3.5
Image: 1
Detected: true
Specimen Num: 2
GXD Expression        
Probe: MGI:5529487
Assay Type: RT-PCR
Annotation Date: 2014-01-21
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5529494
Age: postnatal month 4-6
Specimen Num: 6
GXD Expression        
Probe: MGI:5529487
Assay Type: RT-PCR
Annotation Date: 2014-01-21
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5529494
Age: postnatal month 4-6
Specimen Num: 5
GXD Expression        
Probe: MGI:5529487
Assay Type: RT-PCR
Annotation Date: 2014-01-21
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5529494
Age: postnatal month 4-6
Specimen Num: 8
GXD Expression        
Probe: MGI:5529487
Assay Type: RT-PCR
Annotation Date: 2014-01-21
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5529494
Age: postnatal month 4-6
Specimen Num: 7
GXD Expression      
Probe: MGI:5529487
Assay Type: RT-PCR
Annotation Date: 2014-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5529494
Age: postnatal month 4-6
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5529487
Assay Type: RT-PCR
Annotation Date: 2014-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5529494
Age: postnatal month 4-6
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6189052
Assay Type: RT-PCR
Annotation Date: 2018-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Stage: TS03
Assay Id: MGI:6189087
Age: embryonic day 2.5
Image: 1
Detected: true
Specimen Num: 1
GXD Expression        
Probe: MGI:5529487
Assay Type: RT-PCR
Annotation Date: 2014-01-21
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5529494
Age: postnatal month 4-6
Specimen Num: 2
GXD Expression        
Probe: MGI:5529487
Assay Type: RT-PCR
Annotation Date: 2014-01-21
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5529494
Age: postnatal month 4-6
Specimen Num: 1
GXD Expression  
Probe: MGI:5299067
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2966528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5543051
Age: postnatal day 84
Image: GUDMAP:14452
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5299067
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2849126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543051
Age: embryonic day 17.5
Image: GUDMAP:14451
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5906640
Assay Type: Immunohistochemistry
Annotation Date: 2017-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2849125
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5906872
Age: embryonic day 17.5
Image: GUDMAP:22259
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5299067
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2800326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543051
Age: embryonic day 17.5
Image: GUDMAP:14451
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:4949862
Assay Type: Immunohistochemistry
Annotation Date: 2014-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2800323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5548303
Age: embryonic day 15.5
Image: GUDMAP:8201
Note: signal absent from capillary loop nephrons
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6189066
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360356
Pattern: Not Specified
Stage: TS06
Assay Id: MGI:6189094
Age: embryonic day 4.5
Image: S1A
Detected: true
Specimen Num: 13
GXD Expression
Probe: MGI:6189066
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360356
Pattern: Regionally restricted
Stage: TS06
Assay Id: MGI:6189094
Age: embryonic day 4.5
Image: 5C
Note: Authors report expression is strongly polarized in the epithelium at E4.5. Localization corresponds to future apical side.
Detected: true
Specimen Num: 12
GXD Expression
Probe: MGI:6189066
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360356
Pattern: Regionally restricted
Stage: TS06
Assay Id: MGI:6189094
Age: embryonic day 4.5
Image: 5B
Note: Authors report expression is strongly polarized in the epithelium at E4.5. Localization corresponds to future apical side.
Detected: true
Specimen Num: 11
GXD Expression
Probe: MGI:6189066
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360355
Pattern: Regionally restricted
Stage: TS05
Assay Id: MGI:6189094
Age: embryonic day 3.75
Image: 5A
Note: Polarized expression in E3.75 embryos only in pre-primitive endoderm cells that had lost contact with the blastocoelic cavity. Localization corresponds to future apical side. Authors report strong increase in level of expresion.
Detected: true
Specimen Num: 10
GXD Expression
Probe: MGI:4949862
Assay Type: Immunohistochemistry
Annotation Date: 2014-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2813623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5548303
Age: embryonic day 15.5
Image: GUDMAP:8201
Note: spotted expression; signal in subset of interstitial cells
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4949862
Assay Type: Immunohistochemistry
Annotation Date: 2014-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2812023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5548303
Age: embryonic day 15.5
Image: GUDMAP:8201
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6153169
Assay Type: Immunohistochemistry
Annotation Date: 2018-04-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6153172
Age: embryonic day 8.5
Note: Expression is in clusters adjacent to the vascular sinuses (with little or no endothelial expression) and at the cell surface in cells that surround the ectoplacental cone.
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:6153169
Assay Type: Immunohistochemistry
Annotation Date: 2018-04-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6153173
Age: embryonic day 8.5
Note: Expression is in clusters adjacent to vascular sinuses (with little or no endothelial expression) and at the cell surface in cells that surround the ectoplacental cone.
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6153169
Assay Type: Immunohistochemistry
Annotation Date: 2018-04-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6153172
Age: embryonic day 8.5
Note: Expression is in cells that surround the ectoplacental cone.
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4949862
Assay Type: Immunohistochemistry
Annotation Date: 2014-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2881123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5548303
Age: embryonic day 15.5
Image: GUDMAP:8201
Detected: true
Specimen Num: 1