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Search results 1 to 100 out of 838 for Lrp5

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Akhter MP
Year: 2004
Journal: Bone
Title: Bone biomechanical properties in LRP5 mutant mice.
Volume: 35
Issue: 1
Pages: 162-9
Publication
First Author: Xia CH
Year: 2010
Journal: PLoS One
Title: LRP5 is required for vascular development in deeper layers of the retina.
Volume: 5
Issue: 7
Pages: e11676
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1737322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3276322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Note: Expression was weak in Face/Soft Tissues.
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1783822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1665922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1706822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1674822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1738222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1755022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1733122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3290622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1745822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3278022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1666822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1685322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1718522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1750322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1775122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3287422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1736222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1832122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1741222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3599822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1821522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1702122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1668822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Detected: true
Specimen Num: 1
Publication
First Author: Shahi P
Year: 2012
Journal: PLoS One
Title: Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis.
Volume: 7
Issue: 1
Pages: e30814
Publication
First Author: Cui Y
Year: 2011
Journal: Nat Med
Title: Lrp5 functions in bone to regulate bone mass.
Volume: 17
Issue: 6
Pages: 684-91
Publication
First Author: Huang W
Year: 2016
Journal: PLoS One
Title: Critical Endothelial Regulation by LRP5 during Retinal Vascular Development.
Volume: 11
Issue: 3
Pages: e0152833
Publication
First Author: Sun T
Year: 2017
Journal: PLoS One
Title: miR-375-3p negatively regulates osteogenesis by targeting and decreasing the expression levels of LRP5 and β-catenin.
Volume: 12
Issue: 2
Pages: e0171281
Publication
First Author: Li L
Year: 2018
Journal: Biosci Trends
Title: Heterozygous deletion of LRP5 gene in mice alters profile of immune cells and modulates differentiation of osteoblasts.
Volume: 12
Issue: 3
Pages: 266-274
Publication
First Author: Dubrow SA
Year: 2007
Journal: J Musculoskelet Neuronal Interact
Title: Gender specific LRP5 influences on trabecular bone structure and strength.
Volume: 7
Issue: 2
Pages: 166-73
Publication
First Author: Babij P
Year: 2003
Journal: J Bone Miner Res
Title: High bone mass in mice expressing a mutant LRP5 gene.
Volume: 18
Issue: 6
Pages: 960-74
Publication
First Author: Xia CH
Year: 2013
Journal: PLoS One
Title: Deletion of LRP5 in VLDLR knockout mice inhibits retinal neovascularization.
Volume: 8
Issue: 9
Pages: e75186
Publication
First Author: Zhong Z
Year: 2012
Journal: J Cell Biochem
Title: Lrp5 and Lrp6 play compensatory roles in mouse intestinal development.
Volume: 113
Issue: 1
Pages: 31-8
Publication
First Author: Sawakami K
Year: 2006
Journal: J Biol Chem
Title: The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment.
Volume: 281
Issue: 33
Pages: 23698-711
Publication
First Author: Niziolek PJ
Year: 2015
Journal: J Bone Miner Res
Title: High Bone Mass-Causing Mutant LRP5 Receptors Are Resistant to Endogenous Inhibitors In Vivo.
Volume: 30
Issue: 10
Pages: 1822-30
Publication
First Author: Yadav VK
Year: 2008
Journal: Cell
Title: Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum.
Volume: 135
Issue: 5
Pages: 825-37
Publication  
First Author: Kang KS
Year: 2019
Journal: Bone
Title: Induction of Lrp5 HBM-causing mutations in Cathepsin-K expressing cells alters bone metabolism.
Volume: 120
Pages: 166-175
Publication
First Author: Sebastian A
Year: 2017
Journal: PLoS One
Title: Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts.
Volume: 12
Issue: 11
Pages: e0188264
Publication
First Author: Weaver SR
Year: 2017
Journal: Sci Rep
Title: Characterization of mammary-specific disruptions for Tph1 and Lrp5 during murine lactation.
Volume: 7
Issue: 1
Pages: 15155
Publication
First Author: Joeng KS
Year: 2011
Journal: Dev Biol
Title: Lrp5 and Lrp6 redundantly control skeletal development in the mouse embryo.
Volume: 359
Issue: 2
Pages: 222-9
Publication
First Author: Riddle RC
Year: 2013
Journal: PLoS One
Title: Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisition.
Volume: 8
Issue: 5
Pages: e63323
Publication
First Author: Mammoto T
Year: 2012
Journal: PLoS One
Title: LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway.
Volume: 7
Issue: 7
Pages: e41596
Publication
First Author: Chin EN
Year: 2015
Journal: Mol Cell Biol
Title: Lrp5 Has a Wnt-Independent Role in Glucose Uptake and Growth for Mammary Epithelial Cells.
Volume: 36
Issue: 6
Pages: 871-85
Publication
First Author: Kelly OG
Year: 2004
Journal: Development
Title: The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice.
Volume: 131
Issue: 12
Pages: 2803-15
Publication
First Author: Liedert A
Year: 2014
Journal: PLoS One
Title: Osteoblast-specific Krm2 overexpression and Lrp5 deficiency have different effects on fracture healing in mice.
Volume: 9
Issue: 7
Pages: e103250
Publication
First Author: Ye X
Year: 2009
Journal: Cell
Title: Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization.
Volume: 139
Issue: 2
Pages: 285-98
Publication
First Author: Kim SP
Year: 2017
Journal: Endocrinology
Title: Lack of Lrp5 Signaling in Osteoblasts Sensitizes Male Mice to Diet-Induced Disturbances in Glucose Metabolism.
Volume: 158
Issue: 11
Pages: 3805-3816
Publication
First Author: Young JJ
Year: 2007
Journal: PLoS Pathog
Title: LRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxin.
Volume: 3
Issue: 3
Pages: e27
Publication
First Author: Lindvall C
Year: 2006
Journal: J Biol Chem
Title: The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis.
Volume: 281
Issue: 46
Pages: 35081-7
Publication  
First Author: Lim KE
Year: 2021
Journal: Bone
Title: Co-deletion of Lrp5 and Lrp6 in the skeleton severely diminishes bone gain from sclerostin antibody administration.
Volume: 143
Pages: 115708
Publication
First Author: Liu J
Year: 2019
Journal: FASEB J
Title: Lrp5 and Lrp6 are required for maintaining self-renewal and differentiation of hematopoietic stem cells.
Volume: 33
Issue: 4
Pages: 5615-5625
Publication
First Author: Holmen SL
Year: 2004
Journal: J Bone Miner Res
Title: Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6.
Volume: 19
Issue: 12
Pages: 2033-40
Publication
First Author: Kode A
Year: 2014
Journal: Nat Med
Title: Lrp5 regulation of bone mass and serotonin synthesis in the gut.
Volume: 20
Issue: 11
Pages: 1228-9
Publication
First Author: Haÿ E
Year: 2009
Journal: Mol Cell Biol
Title: N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation.
Volume: 29
Issue: 4
Pages: 953-64
Publication
First Author: Niziolek PJ
Year: 2012
Journal: Bone
Title: Mechanotransduction in bone tissue: The A214V and G171V mutations in Lrp5 enhance load-induced osteogenesis in a surface-selective manner.
Volume: 51
Issue: 3
Pages: 459-65
Publication
First Author: Niziolek PJ
Year: 2015
Journal: PLoS One
Title: Missense Mutations in LRP5 Associated with High Bone Mass Protect the Mouse Skeleton from Disuse- and Ovariectomy-Induced Osteopenia.
Volume: 10
Issue: 11
Pages: e0140775
Publication
First Author: Ellies DL
Year: 2006
Journal: J Bone Miner Res
Title: Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity.
Volume: 21
Issue: 11
Pages: 1738-49
Publication
First Author: Goel S
Year: 2012
Journal: J Biol Chem
Title: Both LRP5 and LRP6 receptors are required to respond to physiological Wnt ligands in mammary epithelial cells and fibroblasts.
Volume: 287
Issue: 20
Pages: 16454-66
Publication
First Author: Galán-Díez M
Year: 2016
Journal: Biochim Biophys Acta
Title: Normal hematopoiesis and lack of β-catenin activation in osteoblasts of patients and mice harboring Lrp5 gain-of-function mutations.
Volume: 1863
Issue: 3
Pages: 490-498
Publication
First Author: Javaheri B
Year: 2012
Journal: PLoS One
Title: Lrp5 is not required for the proliferative response of osteoblasts to strain but regulates proliferation and apoptosis in a cell autonomous manner.
Volume: 7
Issue: 5
Pages: e35726
Publication
First Author: Min Swe NM
Year: 2021
Journal: Dev Dyn
Title: Aberrantly activated Wnt/β-catenin pathway co-receptors LRP5 and LRP6 regulate osteoblast differentiation in the developing coronal sutures of an Apert syndrome (Fgfr2S252W /+ ) mouse model.
Volume: 250
Issue: 3
Pages: 465-476
Publication  
First Author: Kaupp S
Year: 2020
Journal: Bone
Title: Combination therapy in the Col1a2G610C mouse model of Osteogenesis Imperfecta reveals an additive effect of enhancing LRP5 signaling and inhibiting TGFβ signaling on trabecular bone but not on cortical bone.
Volume: 131
Pages: 115084
Publication
First Author: Saxon LK
Year: 2011
Journal: Bone
Title: Analysis of multiple bone responses to graded strains above functional levels, and to disuse, in mice in vivo show that the human Lrp5 G171V High Bone Mass mutation increases the osteogenic response to loading but that lack of Lrp5 activity reduces it.
Volume: 49
Issue: 2
Pages: 184-93
Publication  
First Author: Charette JR
Year: 2017
Journal: Mol Vis
Title: A mutagenesis-derived Lrp5 mouse mutant with abnormal retinal vasculature and low bone mineral density.
Volume: 23
Pages: 140-148
Publication
First Author: Kedlaya R
Year: 2013
Journal: Sci Transl Med
Title: Sclerostin inhibition reverses skeletal fragility in an Lrp5-deficient mouse model of OPPG syndrome.
Volume: 5
Issue: 211
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