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Search results 1 to 100 out of 709 for Lrp6

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0.037s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Bilic J
Year: 2007
Journal: Science
Title: Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation.
Volume: 316
Issue: 5831
Pages: 1619-22
Publication
First Author: Castelo-Branco G
Year: 2010
Journal: Dev Dyn
Title: Delayed dopaminergic neuron differentiation in Lrp6 mutant mice.
Volume: 239
Issue: 1
Pages: 211-21
Publication
First Author: Bikkavilli RK
Year: 2012
Journal: J Cell Sci
Title: Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2.
Volume: 125
Issue: Pt 10
Pages: 2446-56
Publication
First Author: Gray JD
Year: 2010
Journal: Hum Mol Genet
Title: Functional interactions between the LRP6 WNT co-receptor and folate supplementation.
Volume: 19
Issue: 23
Pages: 4560-72
Publication
First Author: Zhong Z
Year: 2012
Journal: J Cell Biochem
Title: Lrp5 and Lrp6 play compensatory roles in mouse intestinal development.
Volume: 113
Issue: 1
Pages: 31-8
Publication
First Author: Pellicelli M
Year: 2018
Journal: Biochim Biophys Acta
Title: Lrp6 is a target of the PTH-activated αNAC transcriptional coregulator.
Volume: 1861
Issue: 2
Pages: 61-71
Publication
First Author: Andersson ER
Year: 2010
Journal: Dev Dyn
Title: Genetic interaction between Lrp6 and Wnt5a during mouse development.
Volume: 239
Issue: 1
Pages: 237-45
Publication
First Author: Wei W
Year: 2006
Journal: Cell
Title: The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin.
Volume: 124
Issue: 6
Pages: 1141-54
Publication
First Author: Jeong W
Year: 2020
Journal: EMBO Rep
Title: LDL receptor-related protein LRP6 senses nutrient levels and regulates Hippo signaling.
Volume: 21
Issue: 9
Pages: e50103
Publication
First Author: Sebastian A
Year: 2017
Journal: PLoS One
Title: Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts.
Volume: 12
Issue: 11
Pages: e0188264
Publication
First Author: Lindvall C
Year: 2009
Journal: PLoS One
Title: The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development.
Volume: 4
Issue: 6
Pages: e5813
Publication
First Author: Kim I
Year: 2013
Journal: J Cell Biol
Title: Clathrin and AP2 are required for PtdIns(4,5)P2-mediated formation of LRP6 signalosomes.
Volume: 200
Issue: 4
Pages: 419-28
Publication  
First Author: Li J
Year: 2016
Journal: Nat Commun
Title: LRP6 acts as a scaffold protein in cardiac gap junction assembly.
Volume: 7
Pages: 11775
Publication
First Author: Zhou CJ
Year: 2010
Journal: Dev Dyn
Title: Generation of Lrp6 conditional gene-targeting mouse line for modeling and dissecting multiple birth defects/congenital anomalies.
Volume: 239
Issue: 1
Pages: 318-26
Publication
First Author: Joeng KS
Year: 2011
Journal: Dev Biol
Title: Lrp5 and Lrp6 redundantly control skeletal development in the mouse embryo.
Volume: 359
Issue: 2
Pages: 222-9
Publication
First Author: Song L
Year: 2010
Journal: Dev Dyn
Title: Cardiac neural crest and outflow tract defects in Lrp6 mutant mice.
Volume: 239
Issue: 1
Pages: 200-10
Publication
First Author: Riddle RC
Year: 2013
Journal: PLoS One
Title: Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisition.
Volume: 8
Issue: 5
Pages: e63323
Publication
First Author: Gray JD
Year: 2013
Journal: Hum Mol Genet
Title: LRP6 exerts non-canonical effects on Wnt signaling during neural tube closure.
Volume: 22
Issue: 21
Pages: 4267-81
Publication
First Author: Wan M
Year: 2011
Journal: Sci Signal
Title: LRP6 mediates cAMP generation by G protein-coupled receptors through regulating the membrane targeting of Gα(s).
Volume: 4
Issue: 164
Pages: ra15
Publication
First Author: Li C
Year: 2013
Journal: J Bone Miner Res
Title: Disruption of LRP6 in osteoblasts blunts the bone anabolic activity of PTH.
Volume: 28
Issue: 10
Pages: 2094-108
Publication
First Author: Kelly OG
Year: 2004
Journal: Development
Title: The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice.
Volume: 131
Issue: 12
Pages: 2803-15
Publication
First Author: Young JJ
Year: 2007
Journal: PLoS Pathog
Title: LRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxin.
Volume: 3
Issue: 3
Pages: e27
Publication
First Author: Liu J
Year: 2019
Journal: FASEB J
Title: Lrp5 and Lrp6 are required for maintaining self-renewal and differentiation of hematopoietic stem cells.
Volume: 33
Issue: 4
Pages: 5615-5625
Publication  
First Author: Lim KE
Year: 2021
Journal: Bone
Title: Co-deletion of Lrp5 and Lrp6 in the skeleton severely diminishes bone gain from sclerostin antibody administration.
Volume: 143
Pages: 115708
Publication
First Author: Kubota T
Year: 2008
Journal: J Bone Miner Res
Title: Lrp6 hypomorphic mutation affects bone mass through bone resorption in mice and impairs interaction with Mesd.
Volume: 23
Issue: 10
Pages: 1661-71
Publication  
First Author: Garg B
Year: 2017
Journal: Cancer Lett
Title: Modulation of post-translational modifications in β-catenin and LRP6 inhibits Wnt signaling pathway in pancreatic cancer.
Volume: 388
Pages: 64-72
Publication
First Author: Cheng SL
Year: 2015
Journal: Circ Res
Title: Vascular smooth muscle LRP6 limits arteriosclerotic calcification in diabetic LDLR-/- mice by restraining noncanonical Wnt signals.
Volume: 117
Issue: 2
Pages: 142-56
Publication
First Author: Kokubu C
Year: 2004
Journal: Development
Title: Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis.
Volume: 131
Issue: 21
Pages: 5469-80
Publication
First Author: Khan Z
Year: 2007
Journal: Mol Cell Biol
Title: Analysis of endogenous LRP6 function reveals a novel feedback mechanism by which Wnt negatively regulates its receptor.
Volume: 27
Issue: 20
Pages: 7291-301
Publication
First Author: Goel S
Year: 2012
Journal: J Biol Chem
Title: Both LRP5 and LRP6 receptors are required to respond to physiological Wnt ligands in mammary epithelial cells and fibroblasts.
Volume: 287
Issue: 20
Pages: 16454-66
Publication
First Author: Adamska M
Year: 2005
Journal: Dev Dyn
Title: Genetic interaction between Wnt7a and Lrp6 during patterning of dorsal and posterior structures of the mouse limb.
Volume: 233
Issue: 2
Pages: 368-72
Publication
First Author: Zhou CJ
Year: 2008
Journal: Dev Dyn
Title: Ocular coloboma and dorsoventral neuroretinal patterning defects in Lrp6 mutant eyes.
Volume: 237
Issue: 12
Pages: 3681-9
Publication
First Author: Nam JS
Year: 2006
Journal: J Biol Chem
Title: Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression.
Volume: 281
Issue: 19
Pages: 13247-57
Publication
First Author: Allache R
Year: 2014
Journal: Hum Mol Genet
Title: Novel mutations in Lrp6 orthologs in mouse and human neural tube defects affect a highly dosage-sensitive Wnt non-canonical planar cell polarity pathway.
Volume: 23
Issue: 7
Pages: 1687-99
Publication
First Author: Min Swe NM
Year: 2021
Journal: Dev Dyn
Title: Aberrantly activated Wnt/β-catenin pathway co-receptors LRP5 and LRP6 regulate osteoblast differentiation in the developing coronal sutures of an Apert syndrome (Fgfr2S252W /+ ) mouse model.
Volume: 250
Issue: 3
Pages: 465-476
Publication
First Author: Koduri V
Year: 2007
Journal: Biochemistry
Title: Requirement for natively unstructured regions of mesoderm development candidate 2 in promoting low-density lipoprotein receptor-related protein 6 maturation.
Volume: 46
Issue: 22
Pages: 6570-7
Publication
First Author: Liu CC
Year: 2014
Journal: Neuron
Title: Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease.
Volume: 84
Issue: 1
Pages: 63-77
Publication
First Author: Brown SD
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family.
Volume: 248
Issue: 3
Pages: 879-88
Publication
First Author: Berger BS
Year: 2017
Journal: EMBO Rep
Title: Parkinson's disease-associated receptor GPR37 is an ER chaperone for LRP6.
Volume: 18
Issue: 5
Pages: 712-725
Publication
First Author: Liu W
Year: 2008
Journal: Circ Res
Title: Mutation in EGFP domain of LDL receptor-related protein 6 impairs cellular LDL clearance.
Volume: 103
Issue: 11
Pages: 1280-8
Publication
First Author: Liu W
Year: 2012
Journal: J Biol Chem
Title: Low density lipoprotein (LDL) receptor-related protein 6 (LRP6) regulates body fat and glucose homeostasis by modulating nutrient sensing pathways and mitochondrial energy expenditure.
Volume: 287
Issue: 10
Pages: 7213-23
Publication
First Author: Wang S
Year: 2015
Journal: FASEB J
Title: Nonalcoholic fatty liver disease induced by noncanonical Wnt and its rescue by Wnt3a.
Volume: 29
Issue: 8
Pages: 3436-45
Publication
First Author: Chen Z
Year: 2018
Journal: Theranostics
Title: Cardiomyocyte-Restricted Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) Deletion Leads to Lethal Dilated Cardiomyopathy Partly Through Drp1 Signaling.
Volume: 8
Issue: 3
Pages: 627-643
Publication
First Author: Liu X
Year: 2013
Journal: Diabetes
Title: Antiangiogenic and antineuroinflammatory effects of kallistatin through interactions with the canonical Wnt pathway.
Volume: 62
Issue: 12
Pages: 4228-38
Publication
First Author: Wang XM
Year: 2019
Journal: Int J Mol Med
Title: Role and mechanisms of action of microRNA‑21 as regards the regulation of the WNT/β‑catenin signaling pathway in the pathogenesis of non‑alcoholic fatty liver disease.
Volume: 44
Issue: 6
Pages: 2201-2212
Publication
First Author: Liu B
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway.
Volume: 110
Issue: 17
Pages: 6877-82
Publication
First Author: Tezuka N
Year: 2007
Journal: Biochem Biophys Res Commun
Title: GRB10 binds to LRP6, the Wnt co-receptor and inhibits canonical Wnt signaling pathway.
Volume: 356
Issue: 3
Pages: 648-54
Publication
First Author: Srivastava R
Year: 2015
Journal: Cell Rep
Title: Impaired LRP6-TCF7L2 Activity Enhances Smooth Muscle Cell Plasticity and Causes Coronary Artery Disease.
Volume: 13
Issue: 4
Pages: 746-759
Publication
First Author: Frey JL
Year: 2015
Journal: Mol Cell Biol
Title: Wnt-Lrp5 signaling regulates fatty acid metabolism in the osteoblast.
Volume: 35
Issue: 11
Pages: 1979-91
Publication  
First Author: Ren DN
Year: 2015
Journal: Nat Commun
Title: LRP5/6 directly bind to Frizzled and prevent Frizzled-regulated tumour metastasis.
Volume: 6
Pages: 6906
Publication
First Author: Wang X
Year: 2019
Journal: Genes Cells
Title: Lipoprotein receptor-related protein 6 is required to maintain intercalated disk integrity.
Volume: 24
Issue: 12
Pages: 789-800
Publication
First Author: Ge M
Year: 2019
Journal: Cell Rep
Title: miR-29a/b1 Inhibits Hair Follicle Stem Cell Lineage Progression by Spatiotemporally Suppressing WNT and BMP Signaling.
Volume: 29
Issue: 8
Pages: 2489-2504.e4
Publication
First Author: Collette NM
Year: 2010
Journal: Dev Biol
Title: Genetic evidence that SOST inhibits WNT signaling in the limb.
Volume: 342
Issue: 2
Pages: 169-79
Publication
First Author: Carter M
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Crooked tail (Cd) model of human folate-responsive neural tube defects is mutated in Wnt coreceptor lipoprotein receptor-related protein 6.
Volume: 102
Issue: 36
Pages: 12843-8
Publication
First Author: Sakaguchi N
Year: 2003
Journal: Neurosci Res
Title: Receptor-type protein tyrosine phosphatase zeta as a component of the signaling receptor complex for midkine-dependent survival of embryonic neurons.
Volume: 45
Issue: 2
Pages: 219-24
Publication
First Author: Sato A
Year: 2010
Journal: EMBO J
Title: Wnt5a regulates distinct signalling pathways by binding to Frizzled2.
Volume: 29
Issue: 1
Pages: 41-54
Publication
First Author: Holmen SL
Year: 2004
Journal: J Bone Miner Res
Title: Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6.
Volume: 19
Issue: 12
Pages: 2033-40
Publication
First Author: Zhou CJ
Year: 2004
Journal: J Neurosci
Title: Wnt signaling mutants have decreased dentate granule cell production and radial glial scaffolding abnormalities.
Volume: 24
Issue: 1
Pages: 121-6
Publication  
First Author: Choi JH
Year: 2019
Journal: Science
Title: LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.
Volume: 364
Issue: 6440
Publication
First Author: Lian G
Year: 2016
Journal: Development
Title: Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway.
Volume: 143
Issue: 23
Pages: 4509-4520
Publication
First Author: MacDonald BT
Year: 2004
Journal: Development
Title: Hypomorphic expression of Dkk1 in the doubleridge mouse: dose dependence and compensatory interactions with Lrp6.
Volume: 131
Issue: 11
Pages: 2543-52
Publication
First Author: Wang H
Year: 2013
Journal: J Biol Chem
Title: SOX9 regulates low density lipoprotein receptor-related protein 6 (LRP6) and T-cell factor 4 (TCF4) expression and Wnt/β-catenin activation in breast cancer.
Volume: 288
Issue: 9
Pages: 6478-87
Publication
First Author: Srivastava R
Year: 2019
Journal: Arterioscler Thromb Vasc Biol
Title: TCF7L2 (Transcription Factor 7-Like 2) Regulation of GATA6 (GATA-Binding Protein 6)-Dependent and -Independent Vascular Smooth Muscle Cell Plasticity and Intimal Hyperplasia.
Volume: 39
Issue: 2
Pages: 250-262
Publication
First Author: Dai TL
Year: 2014
Journal: Exp Ther Med
Title: Depletion of canonical Wnt signaling components has a neuroprotective effect on midbrain dopaminergic neurons in an MPTP-induced mouse model of Parkinson's disease.
Volume: 8
Issue: 2
Pages: 384-390
Publication
First Author: Revollo L
Year: 2015
Journal: J Bone Miner Res
Title: N-cadherin restrains PTH activation of Lrp6/β-catenin signaling and osteoanabolic action.
Volume: 30
Issue: 2
Pages: 274-85
Publication
First Author: Brennan K
Year: 2004
Journal: Oncogene
Title: Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins.
Volume: 23
Issue: 28
Pages: 4873-84
Publication
First Author: Wang K
Year: 2008
Journal: J Biol Chem
Title: Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism.
Volume: 283
Issue: 34
Pages: 23371-5
Publication
First Author: Hsieh JC
Year: 2003
Journal: Cell
Title: Mesd encodes an LRP5/6 chaperone essential for specification of mouse embryonic polarity.
Volume: 112
Issue: 3
Pages: 355-67
Publication
First Author: Wang Z
Year: 2005
Journal: Mol Cell Biol
Title: Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5.
Volume: 25
Issue: 12
Pages: 5022-30
Publication
First Author: Szabó NE
Year: 2011
Journal: PLoS One
Title: Interaction between axons and specific populations of surrounding cells is indispensable for collateral formation in the mammillary system.
Volume: 6
Issue: 5
Pages: e20315
Publication
First Author: Badders NM
Year: 2009
Journal: PLoS One
Title: The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage.
Volume: 4
Issue: 8
Pages: e6594
Publication
First Author: Bryja V
Year: 2009
Journal: Mol Biol Cell
Title: The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo.
Volume: 20
Issue: 3
Pages: 924-36
Publication
First Author: Rajamannan NM
Year: 2011
Journal: J Cell Biochem
Title: The role of Lrp5/6 in cardiac valve disease: experimental hypercholesterolemia in the ApoE-/- /Lrp5-/- mice.
Volume: 112
Issue: 10
Pages: 2987-91
Publication
First Author: Li Y
Year: 2005
Journal: J Cell Sci
Title: Mesd binds to mature LDL-receptor-related protein-6 and antagonizes ligand binding.
Volume: 118
Issue: Pt 22
Pages: 5305-14
Publication
First Author: Bourhis E
Year: 2010
Journal: J Biol Chem
Title: Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6.
Volume: 285
Issue: 12
Pages: 9172-9
Publication
First Author: Ramachandran B
Year: 2018
Journal: J Biol Chem
Title: A GTPase-activating protein-binding protein (G3BP1)/antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells.
Volume: 293
Issue: 21
Pages: 7942-7968
Publication
First Author: Chen HJ
Year: 2006
Journal: Genes Dev
Title: The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway.
Volume: 20
Issue: 14
Pages: 1933-45
Publication
First Author: Pinson KI
Year: 2000
Journal: Nature
Title: An LDL-receptor-related protein mediates Wnt signalling in mice.
Volume: 407
Issue: 6803
Pages: 535-8
Publication
First Author: Fossat N
Year: 2011
Journal: Development
Title: Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo.
Volume: 138
Issue: 4
Pages: 667-76
Publication
First Author: Song L
Year: 2009
Journal: Development
Title: Lrp6-mediated canonical Wnt signaling is required for lip formation and fusion.
Volume: 136
Issue: 18
Pages: 3161-71
Publication
First Author: Zhou Y
Year: 2014
Journal: J Clin Invest
Title: Canonical WNT signaling components in vascular development and barrier formation.
Volume: 124
Issue: 9
Pages: 3825-46
Publication  
First Author: Dash S
Year: 2020
Journal: Front Physiol
Title: The Mediator Subunit, Med23 Is Required for Embryonic Survival and Regulation of Canonical WNT Signaling During Cranial Ganglia Development.
Volume: 11
Pages: 531933
Publication
First Author: Wang Y
Year: 2016
Journal: J Am Soc Nephrol
Title: LDL Receptor-Related Protein 6 Modulates Ret Proto-Oncogene Signaling in Renal Development and Cystic Dysplasia.
Volume: 27
Issue: 2
Pages: 417-27
Publication
First Author: Zhou CJ
Year: 2006
Journal: Neuroscience
Title: Neuronal production and precursor proliferation defects in the neocortex of mice with loss of function in the canonical Wnt signaling pathway.
Volume: 142
Issue: 4
Pages: 1119-31
Publication
First Author: Ahn Y
Year: 2010
Journal: Development
Title: Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning.
Volume: 137
Issue: 19
Pages: 3221-31
Publication
First Author: Sima J
Year: 2016
Journal: Development
Title: Molecular dynamics of Dkk4 modulates Wnt action and regulates meibomian gland development.
Volume: 143
Issue: 24
Pages: 4723-4735
Publication
First Author: Porntaveetus T
Year: 2012
Journal: Eur J Orthod
Title: Wnt signaling in the murine diastema.
Volume: 34
Issue: 4
Pages: 518-24
Publication
First Author: Ellies DL
Year: 2006
Journal: J Bone Miner Res
Title: Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity.
Volume: 21
Issue: 11
Pages: 1738-49
Publication
First Author: Snowball J
Year: 2015
Journal: Dev Biol
Title: Mesenchymal Wnt signaling promotes formation of sternum and thoracic body wall.
Volume: 401
Issue: 2
Pages: 264-75
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus