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Search results 1 to 100 out of 161 for Lsm3

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0.046s
Type Details Score
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Domain
Description: This entry represents Sm-like protein Lsm3. It can be found in the nuclear Lsm2-8 complex or in the cytoplasmic Lsm1-7 complex. The Lsm2-8 complex associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 snRNP, U4/U6.U5 snRNP, and free U6 snRNP). It binds and stabilizes the 3'-terminal poly(U) tract of U6 snRNA and facilitates the assembly of U4-U6 di-snRNP and U4-U6-U5 tri-snRNP [, , ]. The Lsm1-7 complex associates with deadenylated mRNA and promotes decapping in the 5'-3' mRNA decay pathway [, ]. The Sm and the Lsm proteins, characterised by the Sm-domain, have RNA-related functions. The Sm heptamer ring associates with four (U1, U2, U4, U5) snRNPs, while Lsm2-8 heptamer is part of the U6 snRNP. Another Lsm heptameric complex, Lsm1-7, which differs from Lsm2-8 by one Lsm protein, functions in mRNA decapping, a crucial step in the mRNA degradation pathway [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: false
GXD Expression    
Probe: MGI:953618
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3271122
Stage: TS22
Assay Id: MGI:4354897
Age: embryonic day 14.5
Note: There is no expression in either the upper or lower cortical plate.
Specimen Label: Table S5 - Lsm3
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:953618
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354897
Age: embryonic day 14.5
Specimen Label: Table S5 - Lsm3
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:953618
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3270422
Stage: TS22
Assay Id: MGI:4354897
Age: embryonic day 14.5
Specimen Label: Table S5 - Lsm3
Detected: false
Specimen Num: 1
Publication
First Author: Jiang M
Year: 2018
Journal: Cell
Title: Self-Recognition of an Inducible Host lncRNA by RIG-I Feedback Restricts Innate Immune Response.
Volume: 173
Issue: 4
Pages: 906-919.e13
Publication
First Author: Zhou L
Year: 2014
Journal: Nature
Title: Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA.
Volume: 506
Issue: 7486
Pages: 116-20
Publication
First Author: Beggs JD
Year: 2005
Journal: Biochem Soc Trans
Title: Lsm proteins and RNA processing.
Volume: 33
Issue: Pt 3
Pages: 433-8
Publication
First Author: Wu D
Year: 2012
Journal: PLoS One
Title: Crystal structures of Lsm3, Lsm4 and Lsm5/6/7 from Schizosaccharomyces pombe.
Volume: 7
Issue: 5
Pages: e36768
Publication
First Author: He W
Year: 2000
Journal: Curr Opin Cell Biol
Title: Functions of Lsm proteins in mRNA degradation and splicing.
Volume: 12
Issue: 3
Pages: 346-50
Publication
First Author: Zhou L
Year: 2014
Journal: Cell Res
Title: Crystal structure and biochemical analysis of the heptameric Lsm1-7 complex.
Volume: 24
Issue: 4
Pages: 497-500
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
GXD Expression  
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1665821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617165
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617165
Age: embryonic day 13.5
Image: E13.5
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: E13.5
Specimen Num: 1
GXD Expression  
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1760621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617165
Age: embryonic day 13.5
Image: E13.5
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: E13.5
Specimen Num: 1
GXD Expression  
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617165
Age: embryonic day 13.5
Image: E13.5
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: E13.5
Specimen Num: 1
GXD Expression    
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1697427
Stage: TS27
Assay Id: MGI:3617165
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716827
Stage: TS27
Assay Id: MGI:3617165
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1753627
Stage: TS27
Assay Id: MGI:3617165
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3284527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617165
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
GXD Expression  
Probe: MGI:953618
Assay Type: RNA in situ
Annotation Date: 2023-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7526606
Age: embryonic day 14.5
Note: Ventricular zone expression was greater than in the cortical plate.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280927
Stage: TS27
Assay Id: MGI:3617165
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:3617165
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: false
Specimen Num: 2
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:3615020
Assay Type: RT-PCR
Annotation Date: 2006-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3616805
Age: embryonic day 13.5
Specimen Label: RT-PCR E13.5 brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3615020
Assay Type: RT-PCR
Annotation Date: 2006-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3616805
Age: postnatal day 0
Specimen Label: RT-PCR P0 brain
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691627
Stage: TS27
Assay Id: MGI:3617165
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1760627
Stage: TS27
Assay Id: MGI:3617165
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754927
Stage: TS27
Assay Id: MGI:3617165
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1716821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617165
Age: embryonic day 13.5
Image: E13.5
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: E13.5
Specimen Num: 1
GXD Expression    
Probe: MGI:953618
Assay Type: RNA in situ
Annotation Date: 2023-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7526606
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617165
Age: embryonic day 13.5
Image: E13.5
Note: Authors indicate that there was either ubiquitous or background expression in precortical tissue.
Specimen Label: E13.5
Specimen Num: 1
GXD Expression  
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617165
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
GXD Expression    
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1679727
Stage: TS27
Assay Id: MGI:3617165
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754027
Stage: TS27
Assay Id: MGI:3617165
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3267921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617165
Age: embryonic day 13.5
Image: E13.5
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: E13.5
Specimen Num: 1
GXD Expression  
Probe: MGI:3615778
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617165
Age: embryonic day 13.5
Image: E13.5
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: E13.5
Specimen Num: 1
Gene
Type: gene
Organism: human
Publication
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
Publication
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
Publication
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
Publication  
First Author: McKee AE
Year: 2005
Journal: BMC Dev Biol
Title: A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
Volume: 5
Pages: 14
Publication        
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform