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Search results 1 to 100 out of 120 for Lsm7

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Type Details Score
Gene
51690 | LSM7
Type: gene
Organism: human
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Gene
509920 | LSM7
Type: gene
Organism: cattle
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Gene
420055 | LSM7
Type: gene
Organism: chicken
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Gene
573047 | lsm7
Type: gene
Organism: zebrafish
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Gene
721486 | LSM7
Type: gene
Organism: macaque, rhesus
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Gene
100127774 | lsm7
Type: gene
Organism: frog, western clawed
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Gene
362829 | Lsm7
Type: gene
Organism: rat
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Gene
612170 | LSM7
Type: gene
Organism: dog, domestic
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Gene
455572 | LSM7
Type: gene
Organism: chimpanzee
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Protein Domain
IPR017132 | Lsm7
Type: Family
Description: This entry represents Sm-like protein Lsm7. It could be found in the nuclear Lsm2-8 complex or in the cytoplasmic Lsm1-7 complex. The Lsm2-8 complex associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 snRNP, U4/U6.U5 snRNP, and free U6 snRNP). It binds and stabilizes the 3'-terminal poly(U) tract of U6 snRNA and facilitates the assembly of U4-U6 di-snRNP and U4-U6-U5 tri-snRNP [, , ]. The Lsm1-7 complex associates with deadenylated mRNA and promotes decapping in the 5'-3' mRNA decay pathway [, ]. The Sm and the Lsm proteins, characterised by the Sm-domain, have RNA-related functions. The Sm heptamer ring associates with four (U1, U2, U4, U5) snRNPs, while Lsm2-8 heptamer is part of the U6 snRNP. Another Lsm heptameric complex, Lsm1-7, which differs from Lsm2-8 by one Lsm protein, functions in mRNA decapping, a crucial step in the mRNA degradation pathway [].
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Protein Coding Gene
MGI:1913344 | Lsm7
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9CQQ8
Organism: Mus musculus/domesticus
Length: 103  
Fragment?: false
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Publication
24240276 | -
First Author: Zhou L
Year: 2014
Journal: Nature
Title: Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA.
Volume: 506
Issue: 7486
Pages: 116-20
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Publication
15916535 | -
First Author: Beggs JD
Year: 2005
Journal: Biochem Soc Trans
Title: Lsm proteins and RNA processing.
Volume: 33
Issue: Pt 3
Pages: 433-8
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Publication
22615807 | -
First Author: Wu D
Year: 2012
Journal: PLoS One
Title: Crystal structures of Lsm3, Lsm4 and Lsm5/6/7 from Schizosaccharomyces pombe.
Volume: 7
Issue: 5
Pages: e36768
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Publication
10801455 | -
First Author: He W
Year: 2000
Journal: Curr Opin Cell Biol
Title: Functions of Lsm proteins in mRNA degradation and splicing.
Volume: 12
Issue: 3
Pages: 346-50
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Publication
24513854 | -
First Author: Zhou L
Year: 2014
Journal: Cell Res
Title: Crystal structure and biochemical analysis of the heptameric Lsm1-7 complex.
Volume: 24
Issue: 4
Pages: 497-500
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GXD Expression
GXD Expression
     
Probe: MGI:3615024
Assay Type: RT-PCR
Annotation Date: 2006-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3616851
Age: postnatal day 0
Specimen Label: RT-PCR P0 brain
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617515
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617515
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617515
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617515
Age: embryonic day 13.5
Image: E13.5
Note: Expression was detected in precortical tissue.
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617515
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617515
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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Protein Coding Gene
MGP_CAROLIEiJ_G0015607 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017524 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017502 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017463 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017464 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017287 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1913344 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017918 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016854 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017259 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017365 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017359 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017436 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017385 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017959 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016635 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016914 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031020 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016425 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:3615024
Assay Type: RT-PCR
Annotation Date: 2006-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3616851
Age: embryonic day 13.5
Specimen Label: RT-PCR E13.5 brain
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1665821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617515
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617515
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617515
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617515
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617515
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617515
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617515
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617515
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617515
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617515
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617515
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617515
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617515
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3615781
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617515
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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Publication
25288739 | J:216429
First Author: Perez-Santángelo S
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Role for LSM genes in the regulation of circadian rhythms.
Volume: 111
Issue: 42
Pages: 15166-71
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Publication
11591653 | J:103507
First Author: Suzuki H
Year: 2001
Journal: Genome Res
Title: Protein-protein interaction panel using mouse full-length cDNAs.
Volume: 11
Issue: 10
Pages: 1758-65
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Publication
16033648 | J:103446
 
First Author: McKee AE
Year: 2005
Journal: BMC Dev Biol
Title: A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
Volume: 5
Pages: 14
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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UniProt Feature
UniProt Feature
Begin: 2
Description: U6 snRNA-associated Sm-like protein LSm7
Type: chain
End: 103
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Protein
A0A1W2P6N1
Organism: Mus musculus/domesticus
Length: 78  
Fragment?: false
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Gene
102553438 | Lsm7-ps1
Type: gene
Organism: rat
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Gene
120098619 | Lsm7l1
Type: gene
Organism: rat
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Gene
108706793 | lsm7.S
Type: gene
Organism: frog, African clawed
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Gene
444555 | lsm7.L
Type: gene
Organism: frog, African clawed
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Allele
Lsm7<+> | MGI:3048935
   
Name: LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated; wild type
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Allele
Lsm7<Gt(PST10693)Mfgc> | MGI:3860931
 
Name: LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated; gene trap PST10693, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
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Allele
Lsm7<Gt(PST6861)Mfgc> | MGI:4342923
 
Name: LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated; gene trap PST6861, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
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Allele
Lsm7<Gt(PST11439)Mfgc> | MGI:3861782
 
Name: LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated; gene trap PST11439, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
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Allele
Lsm7<tm1e(EUCOMM)Hmgu> | MGI:5013770
Name: LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Lsm7<Gt(PST1414)Mfgc> | MGI:4332430
 
Name: LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated; gene trap PST1414, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
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Allele
Lsm7<Gt(PST6250)Mfgc> | MGI:3860577
 
Name: LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated; gene trap PST6250, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
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Allele
Lsm7<Gt(PST7296)Mfgc> | MGI:3860733
 
Name: LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated; gene trap PST7296, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
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