Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Lymphocyte antigen 86 (LY86, also known as MD-1) is a secretory glycoprotein that regulates subsequent T cell activation and cytokine production [, ]. |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Gorczynski RM |
Year: |
2000 |
Journal: |
J Immunol |
Title: |
Regulation of gene expression of murine MD-1 regulates subsequent T cell activation and cytokine production. |
Volume: |
165 |
Issue: |
4 |
Pages: |
1925-32 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
162
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
90
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsuneyoshi N |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
The functional and structural properties of MD-2 required for lipopolysaccharide binding are absent in MD-1. |
Volume: |
174 |
Issue: |
1 |
Pages: |
340-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Song Z |
Year: |
2020 |
Journal: |
Front Genet |
Title: |
Comprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Non-invasive Early Biomarkers of Alzheimer's Disease in 5XFAD Mouse Model. |
Volume: |
11 |
|
Pages: |
565479 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Nagai Y |
Year: |
2002 |
Journal: |
Blood |
Title: |
Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide. |
Volume: |
99 |
Issue: |
5 |
Pages: |
1699-705 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiong X |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Novel Protective Role of Myeloid Differentiation 1 in Pathological Cardiac Remodelling. |
Volume: |
7 |
|
Pages: |
41857 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peng J |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Loss of MD1 exacerbates pressure overload-induced left ventricular structural and electrical remodelling. |
Volume: |
7 |
Issue: |
1 |
Pages: |
5116 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shuai W |
Year: |
2020 |
Journal: |
Channels (Austin) |
Title: |
The effect of MD1 on potassium and L-type calcium current of cardiomyocytes from high-fat diet mice. |
Volume: |
14 |
Issue: |
1 |
Pages: |
181-189 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gorczynski RM |
Year: |
2006 |
Journal: |
J Immunol |
Title: |
MD1 expression regulates development of regulatory T cells. |
Volume: |
177 |
Issue: |
2 |
Pages: |
1078-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang HJ |
Year: |
2020 |
Journal: |
J Cell Mol Med |
Title: |
MD1 deletion exaggerates cardiomyocyte autophagy induced by heart failure with preserved ejection fraction through ROS/MAPK signalling pathway. |
Volume: |
24 |
Issue: |
16 |
Pages: |
9300-9312 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang X |
Year: |
2019 |
Journal: |
Eur J Pharmacol |
Title: |
Loss of MD1 exacerbates myocardial ischemia/reperfusion injury and susceptibility to ventricular arrhythmia. |
Volume: |
844 |
|
Pages: |
79-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thomas Jennings R |
Year: |
2016 |
Journal: |
Int Immunol |
Title: |
Inflammatory responses increase secretion of MD-1 protein. |
Volume: |
28 |
Issue: |
10 |
Pages: |
503-512 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001357 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1737921 |
Pattern: |
Spotted |
Stage: |
TS21 |
Assay Id: |
MGI:5541912 |
Age: |
embryonic day 13.5 |
Image: |
GUDMAP:10336 |
|
Specimen Label: |
GUDMAP:10336 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001357 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1737321 |
Pattern: |
Spotted |
Stage: |
TS21 |
Assay Id: |
MGI:5541912 |
Age: |
embryonic day 13.5 |
Image: |
GUDMAP:10335 |
|
Specimen Label: |
GUDMAP:10335 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001357 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737323 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541912 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:10767 |
|
Specimen Label: |
GUDMAP:10767 |
Detected: |
false |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001357 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1795921 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5541912 |
Age: |
embryonic day 13.5 |
Image: |
GUDMAP:10337 |
|
Specimen Label: |
GUDMAP:10337 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001357 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1736621 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5541912 |
Age: |
embryonic day 13.5 |
Image: |
GUDMAP:10335 |
|
Specimen Label: |
GUDMAP:10335 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001357 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1736621 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5541912 |
Age: |
embryonic day 13.5 |
Image: |
GUDMAP:10336 |
|
Specimen Label: |
GUDMAP:10336 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001357 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1795023 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541912 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:10767 |
|
Specimen Label: |
GUDMAP:10767 |
Detected: |
false |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001357 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1795023 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541912 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:10768 |
|
Specimen Label: |
GUDMAP:10768 |
Detected: |
false |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001357 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2890921 |
Pattern: |
Spotted |
Stage: |
TS21 |
Assay Id: |
MGI:5541912 |
Age: |
embryonic day 13.5 |
Image: |
GUDMAP:10337 |
|
Specimen Label: |
GUDMAP:10337 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423624 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-09-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754422 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:6456112 |
Age: |
embryonic day 14.5 |
Image: |
S9 |
Note: |
Expression was detected in microglia. |
Specimen Label: |
S9 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001357 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1796821 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5541912 |
Age: |
embryonic day 13.5 |
Image: |
GUDMAP:10334 |
|
Specimen Label: |
GUDMAP:10334 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001357 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2909821 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5541912 |
Age: |
embryonic day 13.5 |
Image: |
GUDMAP:10334 |
|
Specimen Label: |
GUDMAP:10334 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001357 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2913821 |
Pattern: |
Spotted |
Stage: |
TS21 |
Assay Id: |
MGI:5541912 |
Age: |
embryonic day 13.5 |
Image: |
GUDMAP:10334 |
|
Specimen Label: |
GUDMAP:10334 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001357 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1636717 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5541912 |
Age: |
embryonic day 10.5 |
Image: |
GUDMAP:10011 |
Note: |
expression uncertain |
Specimen Label: |
GUDMAP:10011 |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001357 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797221 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:5541912 |
Age: |
embryonic day 13.5 |
Image: |
GUDMAP:10334 |
Note: |
spotted expression |
Specimen Label: |
GUDMAP:10334 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423624 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1914123 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826033 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_011090_01 |
|
Specimen Label: |
euxassay_011090_01 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001357 |
Assay Type: |
RNA in situ |
Annotation Date: |
2025-01-13 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1832623 |
|
Stage: |
TS23 |
Assay Id: |
MGI:7850766 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Supplementary Table 1 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423624 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1914223 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826033 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_011090_01 |
|
Specimen Label: |
euxassay_011090_01 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423624 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1914223 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826033 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_011090_02 |
|
Specimen Label: |
euxassay_011090_02 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423624 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-06-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3523622 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7486451 |
Age: |
embryonic day 14.5 |
Image: |
1D |
|
Specimen Label: |
1D |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423624 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-06-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3523622 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7486451 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001357 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796221 |
Pattern: |
Spotted |
Stage: |
TS21 |
Assay Id: |
MGI:5541912 |
Age: |
embryonic day 13.5 |
Image: |
GUDMAP:10337 |
|
Specimen Label: |
GUDMAP:10337 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyake K |
Year: |
1998 |
Journal: |
J Immunol |
Title: |
Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression. |
Volume: |
161 |
Issue: |
3 |
Pages: |
1348-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sasaki S |
Year: |
2012 |
Journal: |
Mol Immunol |
Title: |
Serum soluble MD-1 levels increase with disease progression in autoimmune prone MRL(lpr/lpr) mice. |
Volume: |
49 |
Issue: |
4 |
Pages: |
611-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2019 |
Journal: |
Molecules |
Title: |
Myeloid Differentiation Protein 2 Mediates Angiotensin II-Induced Liver Inflammation and Fibrosis in Mice. |
Volume: |
25 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shimazu R |
Year: |
1999 |
Journal: |
J Exp Med |
Title: |
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. |
Volume: |
189 |
Issue: |
11 |
Pages: |
1777-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Harrill AH |
Year: |
2009 |
Journal: |
Genome Res |
Title: |
Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans. |
Volume: |
19 |
Issue: |
9 |
Pages: |
1507-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kunda PE |
Year: |
2014 |
Journal: |
Neuroscience |
Title: |
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