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Search results 1 to 100 out of 195 for Ly96

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
23643 | LY96
Type: gene
Organism: human
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Gene
137487879 | ly96
Type: gene
Organism: zebrafish
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Gene
610524 | LY96
Type: gene
Organism: dog, domestic
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Gene
448830 | Ly96
Type: gene
Organism: rat
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Gene
746178 | LY96
Type: gene
Organism: chimpanzee
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Gene
613753 | LY96
Type: gene
Organism: cattle
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Gene
420189 | LY96
Type: gene
Organism: chicken
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Gene
696778 | LY96
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR039217 | LY96
Type: Family
Description: Lymphocyte antigen 96 (LY96 or MD-2) is a glycoprotein essential for the innate response to lipopolysaccharide (LPS), binds to both LPS and the extracellular domain of Toll-like receptor 4 (TLR4) []. LY96 also associates with TLR2, enabling a response to LPS and peptidoglycan from both Gram-positive and Gram-negative bacteria []. The structure of LPS-bound LY96 has been solved, showing that the LPS binds in a deep hydrophobic cavity sandwiched by two beta sheets and that the phosphorylated glucosamine moieties are located at the entrance to the cavity [].
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Protein Coding Gene
MGI:1341909 | Ly96
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
17569869 | -
First Author: Ohto U
Year: 2007
Journal: Science
Title: Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa.
Volume: 316
Issue: 5831
Pages: 1632-4
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Publication
11160242 | -
First Author: Dziarski R
Year: 2001
Journal: J Immunol
Title: MD-2 enables Toll-like receptor 2 (TLR2)-mediated responses to lipopolysaccharide and enhances TLR2-mediated responses to Gram-positive and Gram-negative bacteria and their cell wall components.
Volume: 166
Issue: 3
Pages: 1938-44
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Publication
15175334 | -
First Author: Kennedy MN
Year: 2004
Journal: J Biol Chem
Title: A complex of soluble MD-2 and lipopolysaccharide serves as an activating ligand for Toll-like receptor 4.
Volume: 279
Issue: 33
Pages: 34698-704
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Protein
Q9JHF9
Organism: Mus musculus/domesticus
Length: 160  
Fragment?: false
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Protein
A0A087WQZ9
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: false
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Protein
Q64HC9
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: false
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Protein
Q14AM4
Organism: Mus musculus/domesticus
Length: 160  
Fragment?: false
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Publication
23071439 | J:194866
First Author: Hajjar AM
Year: 2012
Journal: PLoS Pathog
Title: Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica.
Volume: 8
Issue: 10
Pages: e1002963
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Publication
29020088 | J:248428
First Author: Hajjar AM
Year: 2017
Journal: PLoS One
Title: Expression level of human TLR4 rather than sequence is the key determinant of LPS responsiveness.
Volume: 12
Issue: 10
Pages: e0186308
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Protein Coding Gene
MGP_CAROLIEiJ_G0013971 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0015859 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0015840 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0015799 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0015796 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0015630 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1341909 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016250 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015211 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0015603 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0015702 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0015707 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0015774 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0015726 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0016297 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0014995 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0015274 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023848 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0014776 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10891475 | J:62997
First Author: Kato K
Year: 2000
Journal: Blood
Title: ESOP-1, a secreted protein expressed in the hematopoietic, nervous, and reproductive systems of embryonic and adult mice.
Volume: 96
Issue: 1
Pages: 362-4
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Publication
12055629 | J:92494
First Author: Nagai Y
Year: 2002
Journal: Nat Immunol
Title: Essential role of MD-2 in LPS responsiveness and TLR4 distribution.
Volume: 3
Issue: 7
Pages: 667-72
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Publication
28045026 | J:243825
 
First Author: Wang Y
Year: 2017
Journal: Nat Commun
Title: Saturated palmitic acid induces myocardial inflammatory injuries through direct binding to TLR4 accessory protein MD2.
Volume: 8
Pages: 13997
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Publication
26076332 | J:258795
First Author: Wang Y
Year: 2015
Journal: Br J Pharmacol
Title: MD-2 as the target of a novel small molecule, L6H21, in the attenuation of LPS-induced inflammatory response and sepsis.
Volume: 172
Issue: 17
Pages: 4391-405
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Publication
18203970 | J:149717
First Author: Hadina S
Year: 2008
Journal: Am J Respir Cell Mol Biol
Title: MD-2-dependent pulmonary immune responses to inhaled lipooligosaccharides: effect of acylation state.
Volume: 38
Issue: 6
Pages: 647-54
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Publication
35176461 | J:346870
First Author: Qian J
Year: 2022
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Myeloid differential protein-2 inhibition improves diabetic cardiomyopathy via p38MAPK inhibition and AMPK pathway activation.
Volume: 1868
Issue: 5
Pages: 166369
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Publication
32210720 | J:303144
First Author: Rajamanickam V
Year: 2020
Journal: Int J Biol Sci
Title: Selective targeting of the TLR4 co-receptor, MD2, prevents colon cancer growth and lung metastasis.
Volume: 16
Issue: 8
Pages: 1288-1302
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Publication
28726347 | J:258727
First Author: Wang L
Year: 2017
Journal: Obesity (Silver Spring)
Title: MD2 Blockage Protects Obesity-Induced Vascular Remodeling via Activating AMPK/Nrf2.
Volume: 25
Issue: 9
Pages: 1532-1539
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Publication
28965884 | J:254033
First Author: Fang Q
Year: 2018
Journal: Biochim Biophys Acta
Title: Inhibition of myeloid differentiation factor-2 attenuates obesity-induced cardiomyopathy and fibrosis.
Volume: 1864
Issue: 1
Pages: 252-262
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Publication
35343085 | J:334690
First Author: Luo W
Year: 2022
Journal: Clin Transl Med
Title: MD2 deficiency prevents high-fat diet-induced AMPK suppression and lipid accumulation through regulating TBK1 in non-alcoholic fatty liver disease.
Volume: 12
Issue: 3
Pages: e777
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Publication
28322341 | J:275281
 
First Author: Xu Z
Year: 2017
Journal: Sci Rep
Title: Angiotensin II induces kidney inflammatory injury and fibrosis through binding to myeloid differentiation protein-2 (MD2).
Volume: 7
Pages: 44911
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Publication
31254764 | J:310776
 
First Author: Chen H
Year: 2019
Journal: Phytomedicine
Title: Inhibition of myeloid differentiation factor 2 by baicalein protects against acute lung injury.
Volume: 63
Pages: 152997
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Publication
30959575 | J:310777
First Author: Wang Y
Year: 2019
Journal: Br J Pharmacol
Title: Blockade of myeloid differentiation 2 attenuates diabetic nephropathy by reducing activation of the renin-angiotensin system in mouse kidneys.
Volume: 176
Issue: 14
Pages: 2642-2657
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Publication
29111459 | J:260062
 
First Author: Chen H
Year: 2018
Journal: Toxicol Lett
Title: Myeloid differentiation protein 2 induced retinal ischemia reperfusion injury via upregulation of ROS through a TLR4-NOX4 pathway.
Volume: 282
Pages: 109-120
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Publication
28767204 | J:260563
First Author: Fang Q
Year: 2017
Journal: J Cell Mol Med
Title: Blockade of myeloid differentiation protein 2 prevents obesity-induced inflammation and nephropathy.
Volume: 21
Issue: 12
Pages: 3776-3786
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Publication
29077272 | J:260565
First Author: Zhang Y
Year: 2018
Journal: J Cell Mol Med
Title: Inhibition of MD2-dependent inflammation attenuates the progression of non-alcoholic fatty liver disease.
Volume: 22
Issue: 2
Pages: 936-947
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Publication
- | J:265259
     
First Author: Ochoa C
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for pique.
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Publication
19783674 | J:153830
First Author: Vasl J
Year: 2009
Journal: J Immunol
Title: Novel roles of lysines 122, 125, and 58 in functional differences between human and murine MD-2.
Volume: 183
Issue: 8
Pages: 5138-45
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Publication
23583403 | J:201856
First Author: Koo JE
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Sulforaphane inhibits the engagement of LPS with TLR4/MD2 complex by preferential binding to Cys133 in MD2.
Volume: 434
Issue: 3
Pages: 600-5
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Publication
31032920 | J:289694
First Author: Han C
Year: 2019
Journal: J Cell Physiol
Title: The effects and mechanisms of myeloid differentiation protein 2 on intestinal mucosal permeability in mice with chronic colitis.
Volume: 234
Issue: 11
Pages: 21089-21099
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GXD Expression
GXD Expression
     
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:3839646
Age: embryonic day 7.5
Specimen Label: 7.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
       
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3839646
Age: embryonic day 11.5
Specimen Label: 11.5
Specimen Num: 2
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GXD Expression
GXD Expression
       
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:3839646
Age: embryonic day 13.5
Specimen Label: 13.5
Specimen Num: 3
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GXD Expression
GXD Expression
       
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:3839646
Age: embryonic day 15.5
Specimen Label: 15.5
Specimen Num: 4
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GXD Expression
GXD Expression
       
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3839647
Age: postnatal adult
Specimen Label: Brain
Specimen Num: 1
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GXD Expression
GXD Expression
       
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3839647
Age: postnatal adult
Specimen Label: Lung
Specimen Num: 2
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GXD Expression
GXD Expression
       
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3839647
Age: postnatal adult
Specimen Label: Heart
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3839647
Age: postnatal adult
Specimen Label: Liver
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3839647
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:3839647
Age: postnatal adult
Specimen Label: Small intestine
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3839647
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:3839647
Age: postnatal adult
Specimen Label: Ovary
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526928
Stage: TS28
Assay Id: MGI:3839647
Age: embryonic day 8.5
Specimen Label: Decidua
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604213
Stage: TS13
Assay Id: MGI:3839647
Age: embryonic day 8.5
Specimen Label: Decidua
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
       
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:3839647
Age: postnatal adult
Specimen Label: Muscle
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:3839647
Age: postnatal adult
Specimen Label: Skin
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3839647
Age: postnatal adult
Specimen Label: Thymus
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
     
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3839647
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
     
Probe: MGI:3839645
Assay Type: Northern blot
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:3839647
Age: postnatal adult
Specimen Label: Bone marrow
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
   
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3839652
Age: embryonic day 12.5
Specimen Label: 2B viii
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:3839652
Age: embryonic day 12.5
Note: Expression is in the olfactory bulb.
Specimen Label: Not shown
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3839652
Age: embryonic day 12.5
Specimen Label: 2B vii
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608511
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:3839652
Age: embryonic day 7.5
Note: Expression is in the blood islands.
Specimen Label: 2B i
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608513
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:3839652
Age: embryonic day 8.5
Note: Expression is in the spreading vascular network derived from blood islands.
Specimen Label: 2B ii
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608514
Pattern: Regionally restricted
Stage: TS14
Assay Id: MGI:3839652
Age: embryonic day 9.0
Note: Expression is in the spreading vascular network derived from blood islands and in endothelial cells.
Specimen Label: 2B iii, iv
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608514
Pattern: Regionally restricted
Stage: TS14
Assay Id: MGI:3839652
Age: embryonic day 9.0
Note: Expression is in endothelial cells and in blood cells.
Specimen Label: 2B v
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608513
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:3839652
Age: embryonic day 8.5
Note: Expression is in endothelial cells and in blood cells.
Specimen Label: 2B vi
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Present
Sex: Male
Emaps: EMAPS:3147628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3839652
Age: postnatal adult
Specimen Label: 2B x
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:3839652
Age: embryonic day 12.5
Note: Expression is in nipples.
Specimen Label: Not shown
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1698620
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3839652
Age: embryonic day 12.5
Specimen Label: 2B vii
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3839652
Age: embryonic day 12.5
Specimen Label: 2B vii
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3839652
Age: postnatal adult
Specimen Label: 2B ix
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3839652
Age: embryonic day 12.5
Specimen Label: 2B vii
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3839652
Age: embryonic day 12.5
Specimen Label: Not shown
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3839652
Age: embryonic day 12.5
Specimen Label: 2B vii
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3839649
Assay Type: Immunohistochemistry
Annotation Date: 2009-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3562728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3839652
Age: postnatal adult
Note: Authors report expression in oocytes and granulosa cells in all follicles - from small to large, maturated follicles - and that expression become stronger as follicles develop.
Specimen Label: 2B ix
Detected: true
Specimen Num: 8
•
•
•
•
•
Publication
10725698 | J:61404
First Author: Akashi S
Year: 2000
Journal: J Immunol
Title: Cutting edge: cell surface expression and lipopolysaccharide signaling via the toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages.
Volume: 164
Issue: 7
Pages: 3471-5
•
•
•
•
•
Publication
17803912 | J:127195
First Author: Kim HM
Year: 2007
Journal: Cell
Title: Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran.
Volume: 130
Issue: 5
Pages: 906-17
•
•
•
•
•
Publication
22532668 | J:184807
First Author: Ohto U
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2.
Volume: 109
Issue: 19
Pages: 7421-6
•
•
•
•
•
Publication
21233280 | J:171153
First Author: Csak T
Year: 2011
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice.
Volume: 300
Issue: 3
Pages: G433-41
•
•
•
•
•
Publication
21865549 | J:179344
First Author: Meng J
Year: 2011
Journal: J Immunol
Title: Genome-wide expression profiling and mutagenesis studies reveal that lipopolysaccharide responsiveness appears to be absolutely dependent on TLR4 and MD-2 expression and is dependent upon intermolecular ionic interactions.
Volume: 187
Issue: 7
Pages: 3683-93
•
•
•
•
•
Publication
18936141 | J:146686
First Author: Sun Y
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: Inhibition of corneal inflammation by the TLR4 antagonist Eritoran tetrasodium (E5564).
Volume: 50
Issue: 3
Pages: 1247-54
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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