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Search results 1 to 100 out of 362 for Lyst

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: Lysosomal-trafficking regulator (LYST) is a large BEACH domain-containing protein that affects lysosome size and quantity []. LYST controls the terminal maturation of perforin-containing vesicles into secretory granules []. Mutations in the LYST gene causes Chediak-Higashi syndrome, which is a rare autosomal-recessive syndrome characterised by hypopigmentation, severe immune deficiency, a bleeding tendency and progressive neurological dysfunction [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Barbosa MD
Year: 1996
Journal: Nature
Title: Identification of the homologous beige and Chediak-Higashi syndrome genes.
Volume: 382
Issue: 6588
Pages: 262-5
Gene
Type: gene
Organism: Homo sapiens
Publication      
First Author: Gwynn B
Year: 2006
Journal: MGI Direct Data Submission
Title: ENU induced mutation at Lyst locus
Publication
First Author: Holland P
Year: 2014
Journal: Traffic
Title: LYST affects lysosome size and quantity, but not trafficking or degradation through autophagy or endocytosis.
Volume: 15
Issue: 12
Pages: 1390-405
Publication
First Author: Sepulveda FE
Year: 2015
Journal: Traffic
Title: LYST controls the biogenesis of the endosomal compartment required for secretory lysosome function.
Volume: 16
Issue: 2
Pages: 191-203
Publication      
First Author: Blasius AL
Year: 2009
Journal: MGI Direct Data Submission
Title: Charlotte gray is an allele of Lyst and displays pigmentation defects: Record for "charlotte gray" updated January 9th, 2009
Publication
First Author: Misumi DJ
Year: 1997
Journal: Genomics
Title: The physical and genetic map surrounding the Lyst gene on mouse chromosome 13.
Volume: 40
Issue: 1
Pages: 147-50
Publication      
First Author: Samples RM
Year: 2006
Journal: MGI Direct Data Submission
Title: Beige 16 Jackson: a remutation of the Lyst gene
Publication
First Author: Lyst MJ
Year: 2018
Journal: Cell Rep
Title: Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2.
Volume: 24
Issue: 9
Pages: 2213-2220
Publication
First Author: Westphal A
Year: 2017
Journal: J Exp Med
Title: Lysosomal trafficking regulator Lyst links membrane trafficking to toll-like receptor-mediated inflammatory responses.
Volume: 214
Issue: 1
Pages: 227-244
Publication
First Author: Trantow CM
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: Lyst mutation in mice recapitulates iris defects of human exfoliation syndrome.
Volume: 50
Issue: 3
Pages: 1205-14
Publication
First Author: Lyst MJ
Year: 2013
Journal: Nat Neurosci
Title: Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor.
Volume: 16
Issue: 7
Pages: 898-902
Publication      
First Author: Peters LL
Year: 2003
Journal: MGI Direct Data Submission
Title: A remutation at the beige (Lyst) locus arising in an ethylnitrosourea mutagenesis screen
Protein
Organism: Mus musculus
Length: 140  
Fragment?: true
Publication
First Author: Shimazaki H
Year: 2014
Journal: J Neurol Neurosurg Psychiatry
Title: Autosomal-recessive complicated spastic paraplegia with a novel lysosomal trafficking regulator gene mutation.
Volume: 85
Issue: 9
Pages: 1024-8
Publication
First Author: Runkel F
Year: 2006
Journal: Mamm Genome
Title: Grey, a novel mutation in the murine Lyst gene, causes the beige phenotype by skipping of exon 25.
Volume: 17
Issue: 3
Pages: 203-10
Publication      
First Author: Eidenschenk C
Year: 2008
Journal: MGI Direct Data Submission
Title: Grey wolf is an allele of Lyst and a model for Chediak-Higashi Syndrome
Publication      
First Author: Rutschmann S
Year: 2008
Journal: MGI Direct Data Submission
Title: Souris is an allele of Lyst and is a model for Chediak-Higashi Syndrome
Protein
Organism: Mus musculus
Length: 1310  
Fragment?: true
Protein
Organism: Mus musculus
Length: 521  
Fragment?: true
Protein
Organism: Mus musculus
Length: 698  
Fragment?: true
Protein
Organism: Mus musculus
Length: 580  
Fragment?: true
Protein
Organism: Mus musculus
Length: 3788  
Fragment?: false
Protein
Organism: Mus musculus
Length: 3787  
Fragment?: false
Publication      
First Author: Prince L
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for charcoal.
Publication      
First Author: Ishikawa A
Year: 2019
Journal: MGI Direct Data Submission
Title: A new spontaneous mutant allele at the lysosomal trafficking regulator locus in mice.
Publication      
First Author: Reyna C
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for charzard
Publication      
First Author: Reyna C
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for vulpix
Publication
First Author: Hedberg-Buenz A
Year: 2019
Journal: Sci Rep
Title: Mouse models and strain-dependency of Chédiak-Higashi syndrome-associated neurologic dysfunction.
Volume: 9
Issue: 1
Pages: 6752
Publication
First Author: Introne W
Year: 1999
Journal: Mol Genet Metab
Title: Clinical, molecular, and cell biological aspects of Chediak-Higashi syndrome.
Volume: 68
Issue: 2
Pages: 283-303
Publication
First Author: Jessen B
Year: 2011
Journal: Blood
Title: Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome.
Volume: 118
Issue: 17
Pages: 4620-9
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Barbosa MD
Year: 1997
Journal: Hum Mol Genet
Title: Identification of mutations in two major mRNA isoforms of the Chediak-Higashi syndrome gene in human and mouse.
Volume: 6
Issue: 7
Pages: 1091-8
Publication      
First Author: Reyna C
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for robin
Publication      
First Author: Reyna C
Year: 2014
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for 50-cal
Publication      
First Author: Zhang Z
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Swallow
Publication
First Author: Lutzner MA
Year: 1967
Journal: J Hered
Title: Giant granules in leukocytes of the beige mouse.
Volume: 58
Issue: 6
Pages: 299-300
Publication
First Author: Prueitt JL
Year: 1978
Journal: J Lipid Res
Title: Pulmonary surface-active materials in the Chediak-Higashi syndrome.
Volume: 19
Issue: 4
Pages: 410-5
Publication
First Author: Malkinson AM
Year: 1983
Journal: J Natl Cancer Inst
Title: Major effect on susceptibility to urethan-induced pulmonary adenoma by a single gene in BALB/cBy mice.
Volume: 70
Issue: 5
Pages: 931-6
Publication
First Author: Roder JC
Year: 1979
Journal: J Immunol
Title: The beige mutation in the mouse. I. A stem cell predetermined impairment in natural killer cell function.
Volume: 123
Issue: 5
Pages: 2168-73
Publication
First Author: Perou CM
Year: 1997
Journal: J Biol Chem
Title: The Beige/Chediak-Higashi syndrome gene encodes a widely expressed cytosolic protein.
Volume: 272
Issue: 47
Pages: 29790-4
Publication
First Author: Elin RJ
Year: 1974
Journal: Infect Immun
Title: Infection and immunoglobulin concentrations in Chediak-Higashi mice.
Volume: 10
Issue: 1
Pages: 88-91
Publication
First Author: Takeuchi K
Year: 1986
Journal: J Exp Med
Title: Lysosomal elastase and cathepsin G in beige mice. Neutrophils of beige (Chediak-Higashi) mice selectively lack lysosomal elastase and cathepsin G.
Volume: 163
Issue: 3
Pages: 665-77
Publication
First Author: Rasmussen KR
Year: 1992
Journal: Infect Immun
Title: Experimental Cryptosporidium parvum infections in immunosuppressed adult mice.
Volume: 60
Issue: 4
Pages: 1648-52
Publication      
First Author: Clark EA
Year: 1982
Title: The beige (bg) gene influences the development of autoimmune disease in SB/Le male mice
Pages: 301-6
Publication
First Author: Whitney PL
Year: 1992
Journal: Exp Lung Res
Title: Soluble beta-galactoside specific lectin is developmentally regulated in lungs of neonatal black mice and beige mice.
Volume: 18
Issue: 4
Pages: 553-61
Publication
First Author: Swank RT
Year: 1978
Journal: Am J Pathol
Title: Turnover of kidney beta-glucuronidase in normal and Chédiak-Higashi (beige) mice.
Volume: 92
Issue: 3
Pages: 755-72
Publication
First Author: Talmadge JE
Year: 1980
Journal: Nature
Title: Role of NK cells in tumour growth and metastasis in beige mice.
Volume: 284
Issue: 5757
Pages: 622-4
Publication
First Author: Kärre K
Year: 1980
Journal: Nature
Title: Low natural in vivo resistance to syngeneic leukaemias in natural killer-deficient mice.
Volume: 284
Issue: 5757
Pages: 624-6
Publication
First Author: Kaido T
Year: 1993
Journal: Int J Cancer
Title: Sensitized T lymphocytes render DBA/2 beige mice responsive to IFN alpha/beta therapy of Friend erythroleukemia visceral metastases.
Volume: 54
Issue: 3
Pages: 475-81
Publication
First Author: Mathiasen JR
Year: 1987
Journal: Life Sci
Title: C57BL/6J-bgJ (beige) mice: differential sensitivity in the tail flick test to centrally administered mu- and delta-opioid receptor agonists.
Volume: 40
Issue: 20
Pages: 1989-94
Publication
First Author: Appelberg R
Year: 1995
Journal: Infect Immun
Title: Susceptibility of beige mice to Mycobacterium avium: role of neutrophils.
Volume: 63
Issue: 9
Pages: 3381-7
Publication
First Author: Oliver JM
Year: 1976
Journal: Am J Pathol
Title: Impaired microtubule function correctable by cyclic GMP and cholinergic agonists in the Chediak-Higashi syndrome.
Volume: 85
Issue: 2
Pages: 395-418
Publication
First Author: Barthold SW
Year: 1995
Journal: J Infect Dis
Title: Exacerbation of Lyme arthritis in beige mice.
Volume: 172
Issue: 3
Pages: 778-84
Publication
First Author: Haliotis T
Year: 1985
Journal: Int J Cancer
Title: Spontaneous and induced primary oncogenesis in natural killer (NK)-cell-deficient beige mutant mice.
Volume: 35
Issue: 4
Pages: 505-13
Publication
First Author: Takeuchi K
Year: 2000
Journal: Biochim Biophys Acta
Title: A hyperosmotic stress-induced mRNA of carp cell encodes Na(+)- and Cl(-)-dependent high affinity taurine transporter.
Volume: 1464
Issue: 2
Pages: 219-30
Publication
First Author: Pope BL
Year: 1994
Journal: Cell Immunol
Title: Murine strain variation in the natural killer cell and proliferative responses to the immunostimulatory compound 7-allyl-8-oxoguanosine: role of cytokines.
Volume: 159
Issue: 2
Pages: 194-210
Publication
First Author: Perou CM
Year: 1993
Journal: Somat Cell Mol Genet
Title: Complementation analysis of Chediak-Higashi syndrome: the same gene may be responsible for the defect in all patients and species.
Volume: 19
Issue: 5
Pages: 459-68
Publication
First Author: Oliver C
Year: 1975
Journal: Lab Invest
Title: Formation of anomalous lysosomes in monocytes, neutrophils, and eosinophils from bone marrow of mice with Chédiak-Higashi syndrome.
Volume: 32
Issue: 1
Pages: 17-27
Publication
First Author: Shellam GR
Year: 1981
Journal: Proc Natl Acad Sci U S A
Title: Increased susceptibility to cytomegalovirus infection in beige mutant mice.
Volume: 78
Issue: 8
Pages: 5104-8
Publication
First Author: Starcher B
Year: 1989
Journal: Exp Lung Res
Title: The beige mouse: role of neutrophil elastase in the development of pulmonary emphysema.
Volume: 15
Issue: 5
Pages: 785-800
Publication
First Author: Cavarra E
Year: 1999
Journal: Am J Respir Cell Mol Biol
Title: Neutrophil influx into the lungs of beige mice is followed by elastolytic damage and emphysema.
Volume: 20
Issue: 2
Pages: 264-9
Publication
First Author: Tanaka E
Year: 1994
Journal: Exp Lung Res
Title: Effects of the beige mutation on respiratory tract infection with Pseudomonas aeruginosa in mice.
Volume: 20
Issue: 4
Pages: 351-66
Publication
First Author: Kisucka J
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage.
Volume: 103
Issue: 4
Pages: 855-60
Publication
First Author: Kirkpatrick CE
Year: 1982
Journal: Infect Immun
Title: Leishmaniasis in beige mice.
Volume: 38
Issue: 3
Pages: 1208-16
Publication
First Author: Gallin JI
Year: 1974
Journal: Blood
Title: Granulocyte function in the Chediak-Higashi syndrome of mice.
Volume: 43
Issue: 2
Pages: 201-6
Publication
First Author: Chi EY
Year: 1978
Journal: J Histochem Cytochem
Title: Mast cell granule formation in the beige mouse.
Volume: 26
Issue: 2
Pages: 131-7
Publication
First Author: Willingham MC
Year: 1981
Journal: Exp Cell Res
Title: The origin and fate of large dense bodies in beige mouse fibroblasts. Lysosomal fusion and exocytosis.
Volume: 136
Issue: 1
Pages: 157-68
Publication
First Author: Enriquez FJ
Year: 1991
Journal: J Protozool
Title: Cryptosporidium infections in inbred strains of mice.
Volume: 38
Issue: 6
Pages: 100S-102S
Publication
First Author: Guo H
Year: 1992
Journal: Tokai J Exp Clin Med
Title: Cytoarchitectonic abnormalities in cerebellum and hippocampal formation of beige mutant mouse.
Volume: 17
Issue: 1
Pages: 53-61
Publication  
First Author: Roths JB
Year: 1982
Journal: Jackson Lab Ann Rep
Title: The beige mutation retards the progression of autoimmune disease.
Volume: 53
Pages: 65
Publication
First Author: Brandt EJ
Year: 1975
Journal: J Cell Biol
Title: Defective lysosomal enzyme secretion in kidneys of Chediak-Higashi (beige) mice.
Volume: 67
Issue: 3
Pages: 774-88
Publication
First Author: Feith GW
Year: 1993
Journal: Kidney Int
Title: Lack of albuminuria in the early heterologous phase of anti-GBM nephritis in beige mice.
Volume: 43
Issue: 4
Pages: 824-7
Publication
First Author: Perou CM
Year: 1997
Journal: Genomics
Title: The bg allele mutation is due to a LINE1 element retrotransposition.
Volume: 42
Issue: 2
Pages: 366-8
Publication
First Author: Borges R
Year: 2001
Journal: Cell Tissue Res
Title: Morphological and functional characterization of beige mouse adrenomedullary secretory vesicles.
Volume: 304
Issue: 1
Pages: 159-64
Publication
First Author: Oliver C
Year: 1973
Journal: J Histochem Cytochem
Title: Distribution of anomalous lysosomes in the beige mouse: a homologue of Chediak-Higashi syndrome.
Volume: 21
Issue: 3
Pages: 218-28
Publication
First Author: Saxena RK
Year: 1982
Journal: Nature
Title: Defective T-cell response in beige mutant mice.
Volume: 295
Issue: 5846
Pages: 240-1