Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) proteins are cell adhesion molecules expressed on the endothelium in mucosa that guide the specific homing of lymphocytes into mucosal tissues [, ]. MAdCAM-1 belongs to a subclass of the immunoglobulin superfamily (IgSF), whose members are ligands for integrins []. MAdCAM-1 is the major ligand for alpha4beta7 integrin []and the ligand for L-selectin []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Briskin MJ |
Year: |
1993 |
Journal: |
Nature |
Title: |
MAdCAM-1 has homology to immunoglobulin and mucin-like adhesion receptors and to IgA1. |
Volume: |
363 |
Issue: |
6428 |
Pages: |
461-4 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
He C |
Year: |
2023 |
Journal: |
Sci Transl Med |
Title: |
Gut-licensed β7(+) CD4(+) T cells contribute to progressive retinal ganglion cell damage in glaucoma. |
Volume: |
15 |
Issue: |
707 |
Pages: |
eadg1656 |
|
•
•
•
•
•
|
Publication |
First Author: |
Berg EL |
Year: |
1993 |
Journal: |
Nature |
Title: |
L-selectin-mediated lymphocyte rolling on MAdCAM-1. |
Volume: |
366 |
Issue: |
6456 |
Pages: |
695-8 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
405
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
405
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
405
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Tan K |
Year: |
1998 |
Journal: |
Structure |
Title: |
The structure of immunoglobulin superfamily domains 1 and 2 of MAdCAM-1 reveals novel features important for integrin recognition. |
Volume: |
6 |
Issue: |
6 |
Pages: |
793-801 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ogawa T |
Year: |
2004 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Chronic allergy to dietary ovalbumin induces lymphocyte migration to rat small intestinal mucosa that is inhibited by MAdCAM-1. |
Volume: |
286 |
Issue: |
5 |
Pages: |
G702-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Butcher EC |
Year: |
1999 |
Journal: |
Adv Immunol |
Title: |
Lymphocyte trafficking and regional immunity. |
Volume: |
72 |
|
Pages: |
209-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Campbell PK |
Year: |
2002 |
Journal: |
Genetics |
Title: |
Mutation of a novel gene results in abnormal development of spermatid flagella, loss of intermale aggression and reduced body fat in mice. |
Volume: |
162 |
Issue: |
1 |
Pages: |
307-20 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Sampaio SO |
Year: |
1995 |
Journal: |
J Immunol |
Title: |
Organization, regulatory sequences, and alternatively spliced transcripts of the mucosal addressin cell adhesion molecule-1 (MAdCAM-1) gene. |
Volume: |
155 |
Issue: |
5 |
Pages: |
2477-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schiffer SG |
Year: |
1995 |
Journal: |
Biochem Biophys Res Commun |
Title: |
An alternately spliced mRNA encoding functional domains of murine MAdCAM-1. |
Volume: |
216 |
Issue: |
1 |
Pages: |
170-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schippers A |
Year: |
2009 |
Journal: |
Gastroenterology |
Title: |
Mucosal addressin cell-adhesion molecule-1 controls plasma-cell migration and function in the small intestine of mice. |
Volume: |
137 |
Issue: |
3 |
Pages: |
924-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kuhbandner K |
Year: |
2019 |
Journal: |
Front Immunol |
Title: |
MAdCAM-1-Mediated Intestinal Lymphocyte Homing Is Critical for the Development of Active Experimental Autoimmune Encephalomyelitis. |
Volume: |
10 |
|
Pages: |
903 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shigematsu T |
Year: |
2001 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
MAdCAM mediates lymphocyte-endothelial cell adhesion in a murine model of chronic colitis. |
Volume: |
281 |
Issue: |
5 |
Pages: |
G1309-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kanwar JR |
Year: |
2000 |
Journal: |
Immunol Cell Biol |
Title: |
Prevention of a chronic progressive form of experimental autoimmune encephalomyelitis by an antibody against mucosal addressin cell adhesion molecule-1, given early in the course of disease progression. |
Volume: |
78 |
Issue: |
6 |
Pages: |
641-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shyjan AM |
Year: |
1996 |
Journal: |
J Immunol |
Title: |
Human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) demonstrates structural and functional similarities to the alpha 4 beta 7-integrin binding domains of murine MAdCAM-1, but extreme divergence of mucin-like sequences. |
Volume: |
156 |
Issue: |
8 |
Pages: |
2851-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Viney JL |
Year: |
1996 |
Journal: |
J Immunol |
Title: |
Mucosal addressin cell adhesion molecule-1: a structural and functional analysis demarcates the integrin binding motif. |
Volume: |
157 |
Issue: |
6 |
Pages: |
2488-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Döring A |
Year: |
2011 |
Journal: |
Eur J Immunol |
Title: |
TET inducible expression of the α4β7-integrin ligand MAdCAM-1 on the blood-brain barrier does not influence the immunopathogenesis of experimental autoimmune encephalomyelitis. |
Volume: |
41 |
Issue: |
3 |
Pages: |
813-21 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7572960 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-01-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3648122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7574115 |
Age: |
embryonic day 14.5 |
Image: |
1B MAdCAM-1 bottom |
|
Specimen Label: |
1B MAdCAM-1 bottom |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7572960 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-01-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3648122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7574115 |
Age: |
embryonic day 14.5 |
Image: |
S1A MAdCAM-1 |
Note: |
Expression restricted to placode cells. |
Specimen Label: |
S1A MAdCAM-1 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416051 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1853523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826054 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_010430_02 |
|
Specimen Label: |
euxassay_010430_02 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416051 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1853523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826054 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_010430_03 |
|
Specimen Label: |
euxassay_010430_03 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416051 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1853523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826054 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_010430_04 |
|
Specimen Label: |
euxassay_010430_04 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416051 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1853523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826054 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_010430_05 |
|
Specimen Label: |
euxassay_010430_05 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416051 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1853523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826054 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_010430_06 |
|
Specimen Label: |
euxassay_010430_06 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416051 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1853523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826054 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_010430_07 |
|
Specimen Label: |
euxassay_010430_07 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7572960 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-01-18 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3553621 |
|
Stage: |
TS21 |
Assay Id: |
MGI:7574502 |
Age: |
embryonic day 13.5 |
Image: |
S2A Eda-/- |
|
Specimen Label: |
S2A Eda-/- |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7572960 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-01-18 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3553621 |
|
Stage: |
TS21 |
Assay Id: |
MGI:7574502 |
Age: |
embryonic day 13.5 |
Image: |
S2A wt |
|
Specimen Label: |
S2A wt |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5634487 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-05-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3556128 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:5634488 |
Age: |
postnatal day 4 |
|
Note: |
Expression is in high endothelial venules. |
Specimen Label: |
8B |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4461434 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2010-07-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1782921 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:4461448 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
2B |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4461434 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2010-07-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1877122 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:4461448 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was detected in the hair buds over almost the entire body of the embryo. |
Specimen Label: |
1B |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4461434 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2010-07-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1877122 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:4461448 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was detected in hair buds. |
Specimen Label: |
1B inset |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4461434 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2010-07-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1877122 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:4461448 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was detected in hair placodes. |
Specimen Label: |
2C |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4461434 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2010-07-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1877123 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:4461448 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
2D |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4461434 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2010-07-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1877122 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:4461448 |
Age: |
embryonic day 14.5-15.5 |
|
Note: |
Expression was detected in the hair placode. |
Specimen Label: |
not shown |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4461434 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2010-07-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1877124 |
Pattern: |
Regionally restricted |
Stage: |
TS24 |
Assay Id: |
MGI:4461448 |
Age: |
embryonic day 16.5 |
|
Note: |
Expression was detected in newly formed hair placodes. |
Specimen Label: |
not shown |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4461434 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2010-07-23 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1877125 |
|
Stage: |
TS25 |
Assay Id: |
MGI:4461448 |
Age: |
embryonic day 17.5-18.5 |
|
Note: |
Expression was not detected in hair placodes or elongating hair follicles. |
Specimen Label: |
not shown |
Detected: |
false |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4461434 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2018-01-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876526 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:6107835 |
Age: |
embryonic day 18.5 |
Image: |
B Dse+/+;Dsel-/- |
Note: |
Expression is in stromal cells in the peripheral lymph node. |
Specimen Label: |
B Dse+/+;Dsel-/- |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4461434 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2018-01-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876526 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:6107835 |
Age: |
embryonic day 18.5 |
Image: |
B DKO |
Note: |
Expression is the same as in Dse+/+;Dsel-/- lymph nodes. |
Specimen Label: |
B DKO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7572960 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-01-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3639222 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:7574115 |
Age: |
embryonic day 14.5 |
Image: |
1B MAdCAM-1 top |
|
Specimen Label: |
1B MAdCAM-1 top |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4461434 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2010-07-23 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752524 |
|
Stage: |
TS24 |
Assay Id: |
MGI:4461448 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
not shown |
Detected: |
false |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4461434 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2010-07-23 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752522 |
|
Stage: |
TS22 |
Assay Id: |
MGI:4461448 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
3A |
Detected: |
false |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4461434 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2010-07-23 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752523 |
|
Stage: |
TS23 |
Assay Id: |
MGI:4461448 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
3B |
Detected: |
false |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4461434 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2010-07-23 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752522 |
|
Stage: |
TS22 |
Assay Id: |
MGI:4461448 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
3C |
Detected: |
false |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4461434 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2010-07-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752522 |
Pattern: |
Spotted |
Stage: |
TS22 |
Assay Id: |
MGI:4461448 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
3D |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4461434 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2010-07-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:2672020 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4461448 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
2A |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6450199 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3699728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6450204 |
Age: |
postnatal adult |
Image: |
S2B WT |
|
Specimen Label: |
S2B WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6450199 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3699728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6450204 |
Age: |
postnatal adult |
Image: |
S2B STING N153S |
Note: |
Authors stage that expression remained intact in the mutant spleen. |
Specimen Label: |
S2B STING N153S |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fidelle M |
Year: |
2023 |
Journal: |
Science |
Title: |
A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers. |
Volume: |
380 |
Issue: |
6649 |
Pages: |
eabo2296 |
|
•
•
•
•
•
|
Publication |
First Author: |
Picarella D |
Year: |
1997 |
Journal: |
J Immunol |
Title: |
Monoclonal antibodies specific for beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) reduce inflammation in the colon of scid mice reconstituted with CD45RBhigh CD4+ T cells. |
Volume: |
158 |
Issue: |
5 |
Pages: |
2099-106 |
|
•
•
•
•
•
|
Publication |
First Author: |
Teramoto K |
Year: |
2005 |
Journal: |
Clin Exp Immunol |
Title: |
Increased lymphocyte trafficking to colonic microvessels is dependent on MAdCAM-1 and C-C chemokine mLARC/CCL20 in DSS-induced mice colitis. |
Volume: |
139 |
Issue: |
3 |
Pages: |
421-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koike R |
Year: |
1997 |
Journal: |
Cell Immunol |
Title: |
Analysis of expression of lymphocyte homing-related adhesion molecules in ALY mice deficient in lymph nodes and Peyer's patches. |
Volume: |
180 |
Issue: |
1 |
Pages: |
62-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Berlin C |
Year: |
1993 |
Journal: |
Cell |
Title: |
Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. |
Volume: |
74 |
Issue: |
1 |
Pages: |
185-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pabst O |
Year: |
2000 |
Journal: |
EMBO J |
Title: |
NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue. |
Volume: |
19 |
Issue: |
9 |
Pages: |
2015-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mizushima T |
Year: |
2010 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Blockage of angiotensin II type 1 receptor regulates TNF-alpha-induced MAdCAM-1 expression via inhibition of NF-kappaB translocation to the nucleus and ameliorates colitis. |
Volume: |
298 |
Issue: |
2 |
Pages: |
G255-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vojkovics D |
Year: |
2019 |
Journal: |
Front Immunol |
Title: |
Differential Effects of the Absence of Nkx2-3 and MAdCAM-1 on the Distribution of Intestinal Type 3 Innate Lymphoid Cells and Postnatal SILT Formation in Mice. |
Volume: |
10 |
|
Pages: |
366 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsuzaki K |
Year: |
2005 |
Journal: |
Clin Exp Immunol |
Title: |
In vivo demonstration of T lymphocyte migration and amelioration of ileitis in intestinal mucosa of SAMP1/Yit mice by the inhibition of MAdCAM-1. |
Volume: |
140 |
Issue: |
1 |
Pages: |
22-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ueha S |
Year: |
2007 |
Journal: |
J Leukoc Biol |
Title: |
Intervention of MAdCAM-1 or fractalkine alleviates graft-versus-host reaction associated intestinal injury while preserving graft-versus-tumor effects. |
Volume: |
81 |
Issue: |
1 |
Pages: |
176-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Burke SD |
Year: |
2007 |
Journal: |
Diabetes |
Title: |
Aberrant endometrial features of pregnancy in diabetic NOD mice. |
Volume: |
56 |
Issue: |
12 |
Pages: |
2919-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fernekorn U |
Year: |
2004 |
Journal: |
Eur J Immunol |
Title: |
Functional involvement of P-selectin and MAdCAM-1 in the recruitment of alpha4beta7-integrin-expressing monocyte-like cells to the pregnant mouse uterus. |
Volume: |
34 |
Issue: |
12 |
Pages: |
3423-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu Y |
Year: |
2007 |
Journal: |
Immunol Cell Biol |
Title: |
The correlation between proinflammatory cytokines, MAdCAM-1 and cellular infiltration in the inflamed colon from TNF-alpha gene knockout mice. |
Volume: |
85 |
Issue: |
8 |
Pages: |
633-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang C |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Alpha4beta7/MAdCAM-1 interactions play an essential role in transitioning cryptopatches into isolated lymphoid follicles and a nonessential role in cryptopatch formation. |
Volume: |
181 |
Issue: |
6 |
Pages: |
4052-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hadis U |
Year: |
2011 |
Journal: |
Immunity |
Title: |
Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria. |
Volume: |
34 |
Issue: |
2 |
Pages: |
237-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kellermayer Z |
Year: |
2019 |
Journal: |
J Immunol |
Title: |
IL-22-Independent Protection from Colitis in the Absence of Nkx2.3 Transcription Factor in Mice. |
Volume: |
202 |
Issue: |
6 |
Pages: |
1833-1844 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hoshino H |
Year: |
2011 |
Journal: |
J Histochem Cytochem |
Title: |
An integrin alpha4beta7•IgG heterodimeric chimera binds to MAdCAM-1 on high endothelial venules in gut-associated lymphoid tissue. |
Volume: |
59 |
Issue: |
6 |
Pages: |
572-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abonia JP |
Year: |
2006 |
Journal: |
Blood |
Title: |
Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for recruitment of mast cell progenitors to the inflamed lung. |
Volume: |
108 |
Issue: |
5 |
Pages: |
1588-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Katayama Y |
Year: |
2004 |
Journal: |
Blood |
Title: |
Integrin alpha4beta7 and its counterreceptor MAdCAM-1 contribute to hematopoietic progenitor recruitment into bone marrow following transplantation. |
Volume: |
104 |
Issue: |
7 |
Pages: |
2020-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Murai M |
Year: |
2003 |
Journal: |
Nat Immunol |
Title: |
Peyer's patch is the essential site in initiating murine acute and lethal graft-versus-host reaction. |
Volume: |
4 |
Issue: |
2 |
Pages: |
154-60 |
|
•
•
•
•
•
|