| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Maf transcription factors form a distinct family of the basic leucine zipper (bZip) transcription factors. The Maf family is divided into two subclasses, large Mafs (c-maf, mafB, and mafA/L-maf, nrl) and small Mafs (MafF, MafK and MafG). Both subclasses contain leucine-zipper motifs, which allow homodimerisation as well as heterodimerisation with a variety of other bZip proteins. In contrast to the small Mafs, the large Maf proteins contain a transactivator domain in their amino terminus []. The small Maf proteins might contribute to oncogenic processes by participating in antioxidant responses, while large Maf proteins have been directly implicated in carcinogenesis []. This entry represents MafA. MafA plays a critical role in the regulation of crystalline genes and lens development [, ]. It also binds the insulin enhancer element RIPE3b and regulates the insulin gene transcription [, , ]. |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang C |
| Year: |
2005 |
| Journal: |
Mol Cell Biol |
| Title: |
MafA is a key regulator of glucose-stimulated insulin secretion. |
| Volume: |
25 |
| Issue: |
12 |
| Pages: |
4969-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao L |
| Year: |
2005 |
| Journal: |
J Biol Chem |
| Title: |
The islet beta cell-enriched MafA activator is a key regulator of insulin gene transcription. |
| Volume: |
280 |
| Issue: |
12 |
| Pages: |
11887-94 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6449789 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-08-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3292723 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:6449813 |
| Age: |
embryonic day 15.5 |
| Image: |
S1 E15.5 MafA |
| Note: |
Expression overlaps with that of Myt1. |
| Specimen Label: |
S1 E15.5 MafA |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6449789 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-08-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750321 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:6449813 |
| Age: |
embryonic day 13.5 |
| Image: |
S1 E13.5 MafA |
| Note: |
Expression overlaps with that of Myt1. |
| Specimen Label: |
S1 E13.5 MafA |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
359
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5789282 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2016-08-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716320 |
|
| Stage: |
TS20 |
| Assay Id: |
MGI:5789314 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
mafA |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Eychène A |
| Year: |
2008 |
| Journal: |
Nat Rev Cancer |
| Title: |
A new MAFia in cancer. |
| Volume: |
8 |
| Issue: |
9 |
| Pages: |
683-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ogino H |
| Year: |
1998 |
| Journal: |
Science |
| Title: |
Induction of lens differentiation by activation of a bZIP transcription factor, L-Maf. |
| Volume: |
280 |
| Issue: |
5360 |
| Pages: |
115-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Olbrot M |
| Year: |
2002 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA. |
| Volume: |
99 |
| Issue: |
10 |
| Pages: |
6737-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Benkhelifa S |
| Year: |
1998 |
| Journal: |
Oncogene |
| Title: |
mafA, a novel member of the maf proto-oncogene family, displays developmental regulation and mitogenic capacity in avian neuroretina cells. |
| Volume: |
17 |
| Issue: |
2 |
| Pages: |
247-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kataoka K |
| Year: |
2002 |
| Journal: |
J Biol Chem |
| Title: |
MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene. |
| Volume: |
277 |
| Issue: |
51 |
| Pages: |
49903-10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kajihara M |
| Year: |
2003 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Mouse MafA, homologue of zebrafish somite Maf 1, contributes to the specific transcriptional activity through the insulin promoter. |
| Volume: |
312 |
| Issue: |
3 |
| Pages: |
831-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lecoin L |
| Year: |
2010 |
| Journal: |
Dev Neurobiol |
| Title: |
MafA transcription factor identifies the early ret-expressing sensory neurons. |
| Volume: |
70 |
| Issue: |
7 |
| Pages: |
485-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matsuoka TA |
| Year: |
2003 |
| Journal: |
Mol Cell Biol |
| Title: |
Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells. |
| Volume: |
23 |
| Issue: |
17 |
| Pages: |
6049-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Eto K |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
MafA is required for postnatal proliferation of pancreatic β-cells. |
| Volume: |
9 |
| Issue: |
8 |
| Pages: |
e104184 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Singh T |
| Year: |
2019 |
| Journal: |
Sci Rep |
| Title: |
Loss of MafA and MafB expression promotes islet inflammation. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
9074 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6449762 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-08-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750321 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:6449800 |
| Age: |
embryonic day 13.5 |
| Image: |
S1 E13.5 MafA |
| Note: |
Expression overlaps with expression of Mafa. |
| Specimen Label: |
S1 E13.5 MafA |
| Detected: |
true |
| Specimen Num: |
21 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6449762 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-08-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3292723 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:6449800 |
| Age: |
embryonic day 15.5 |
| Image: |
S1 E15.5 MafA |
|
| Specimen Label: |
S1 E15.5 MafA |
| Detected: |
true |
| Specimen Num: |
25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hang Y |
| Year: |
2014 |
| Journal: |
Diabetes |
| Title: |
The MafA transcription factor becomes essential to islet β-cells soon after birth. |
| Volume: |
63 |
| Issue: |
6 |
| Pages: |
1994-2005 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kitamura YI |
| Year: |
2005 |
| Journal: |
Cell Metab |
| Title: |
FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction. |
| Volume: |
2 |
| Issue: |
3 |
| Pages: |
153-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nishimura W |
| Year: |
2009 |
| Journal: |
Dev Biol |
| Title: |
Expression of MafA in pancreatic progenitors is detrimental for pancreatic development. |
| Volume: |
333 |
| Issue: |
1 |
| Pages: |
108-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Artner I |
| Year: |
2008 |
| Journal: |
J Endocrinol |
| Title: |
MafA is a dedicated activator of the insulin gene in vivo. |
| Volume: |
198 |
| Issue: |
2 |
| Pages: |
271-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matsuoka TA |
| Year: |
2010 |
| Journal: |
Diabetes |
| Title: |
Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes. |
| Volume: |
59 |
| Issue: |
7 |
| Pages: |
1709-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matsuoka TA |
| Year: |
2015 |
| Journal: |
J Biol Chem |
| Title: |
Preserving Mafa expression in diabetic islet β-cells improves glycemic control in vivo. |
| Volume: |
290 |
| Issue: |
12 |
| Pages: |
7647-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nishimura W |
| Year: |
2015 |
| Journal: |
Diabetologia |
| Title: |
MafA is critical for maintenance of the mature beta cell phenotype in mice. |
| Volume: |
58 |
| Issue: |
3 |
| Pages: |
566-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bourane S |
| Year: |
2009 |
| Journal: |
Neuron |
| Title: |
Low-threshold mechanoreceptor subtypes selectively express MafA and are specified by Ret signaling. |
| Volume: |
64 |
| Issue: |
6 |
| Pages: |
857-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Luan C |
| Year: |
2019 |
| Journal: |
Commun Biol |
| Title: |
The calcium channel subunit gamma-4 is regulated by MafA and necessary for pancreatic beta-cell specification. |
| Volume: |
2 |
|
| Pages: |
106 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Noso S |
| Year: |
2010 |
| Journal: |
Diabetes |
| Title: |
Insulin transactivator MafA regulates intrathymic expression of insulin and affects susceptibility to type 1 diabetes. |
| Volume: |
59 |
| Issue: |
10 |
| Pages: |
2579-87 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Artner I |
| Year: |
2010 |
| Journal: |
Diabetes |
| Title: |
MafA and MafB regulate genes critical to beta-cells in a unique temporal manner. |
| Volume: |
59 |
| Issue: |
10 |
| Pages: |
2530-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nishimura W |
| Year: |
2006 |
| Journal: |
Dev Biol |
| Title: |
A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. |
| Volume: |
293 |
| Issue: |
2 |
| Pages: |
526-39 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matsuoka TA |
| Year: |
2017 |
| Journal: |
Diabetes |
| Title: |
Mafa Enables Pdx1 to Effectively Convert Pancreatic Islet Progenitors and Committed Islet α-Cells Into β-Cells In Vivo. |
| Volume: |
66 |
| Issue: |
5 |
| Pages: |
1293-1300 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yamamoto K |
| Year: |
2013 |
| Journal: |
J Biol Chem |
| Title: |
A novel function of Onecut1 protein as a negative regulator of MafA gene expression. |
| Volume: |
288 |
| Issue: |
30 |
| Pages: |
21648-58 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Scoville DW |
| Year: |
2015 |
| Journal: |
Diabetes |
| Title: |
MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function. |
| Volume: |
64 |
| Issue: |
11 |
| Pages: |
3772-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Harmon JS |
| Year: |
2009 |
| Journal: |
Endocrinology |
| Title: |
beta-Cell-specific overexpression of glutathione peroxidase preserves intranuclear MafA and reverses diabetes in db/db mice. |
| Volume: |
150 |
| Issue: |
11 |
| Pages: |
4855-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhu K |
| Year: |
2020 |
| Journal: |
Nat Commun |
| Title: |
Kindlin-2 modulates MafA and β-catenin expression to regulate β-cell function and mass in mice. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
484 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Walker EM |
| Year: |
2021 |
| Journal: |
Cell Rep |
| Title: |
Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males. |
| Volume: |
37 |
| Issue: |
2 |
| Pages: |
109813 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao X |
| Year: |
2012 |
| Journal: |
J Biol Chem |
| Title: |
MicroRNA-30d induces insulin transcription factor MafA and insulin production by targeting mitogen-activated protein 4 kinase 4 (MAP4K4) in pancreatic β-cells. |
| Volume: |
287 |
| Issue: |
37 |
| Pages: |
31155-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ganic E |
| Year: |
2015 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Islet-specific monoamine oxidase A and B expression depends on MafA transcriptional activity and is compromised in type 2 diabetes. |
| Volume: |
468 |
| Issue: |
4 |
| Pages: |
629-35 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Birchmeier C |
| Year: |
2016 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Submission for a Mafa-cre |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matsuoka TA |
| Year: |
2004 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
The MafA transcription factor appears to be responsible for tissue-specific expression of insulin. |
| Volume: |
101 |
| Issue: |
9 |
| Pages: |
2930-3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lecoin L |
| Year: |
2022 |
| Journal: |
Nat Commun |
| Title: |
Mafa-dependent GABAergic activity promotes mouse neonatal apneas. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
3284 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shimohata H |
| Year: |
2009 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
MafA-deficient and beta cell-specific MafK-overexpressing hybrid transgenic mice develop human-like severe diabetic nephropathy. |
| Volume: |
389 |
| Issue: |
2 |
| Pages: |
235-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He KH |
| Year: |
2014 |
| Journal: |
Dev Biol |
| Title: |
Differentiation of pancreatic endocrine progenitors reversibly blocked by premature induction of MafA. |
| Volume: |
385 |
| Issue: |
1 |
| Pages: |
2-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kanai K |
| Year: |
2010 |
| Journal: |
Genes Cells |
| Title: |
SUMOylation negatively regulates transcriptional and oncogenic activities of MafA. |
| Volume: |
15 |
| Issue: |
9 |
| Pages: |
971-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nishimura W |
| Year: |
2015 |
| Journal: |
Endocr J |
| Title: |
Generation and characterization of MafA-Kusabira Orange mice. |
| Volume: |
62 |
| Issue: |
1 |
| Pages: |
37-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ganic E |
| Year: |
2016 |
| Journal: |
Cell Rep |
| Title: |
MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes. |
| Volume: |
14 |
| Issue: |
8 |
| Pages: |
1991-2002 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu G |
| Year: |
2013 |
| Journal: |
Nat Med |
| Title: |
Thioredoxin-interacting protein regulates insulin transcription through microRNA-204. |
| Volume: |
19 |
| Issue: |
9 |
| Pages: |
1141-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Deng Z |
| Year: |
2020 |
| Journal: |
Int J Mol Sci |
| Title: |
An Inducible Diabetes Mellitus Murine Model Based on MafB Conditional Knockout under MafA-Deficient Condition. |
| Volume: |
21 |
| Issue: |
16 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nomoto H |
| Year: |
2015 |
| Journal: |
Endocrinology |
| Title: |
Inhibition of Small Maf Function in Pancreatic β-Cells Improves Glucose Tolerance Through the Enhancement of Insulin Gene Transcription and Insulin Secretion. |
| Volume: |
156 |
| Issue: |
10 |
| Pages: |
3570-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takeuchi T |
| Year: |
2009 |
| Journal: |
Genes Cells |
| Title: |
Neither MafA/L-Maf nor MafB is essential for lens development in mice. |
| Volume: |
14 |
| Issue: |
8 |
| Pages: |
941-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Arcourt A |
| Year: |
2017 |
| Journal: |
Neuron |
| Title: |
Touch Receptor-Derived Sensory Information Alleviates Acute Pain Signaling and Fine-Tunes Nociceptive Reflex Coordination. |
| Volume: |
93 |
| Issue: |
1 |
| Pages: |
179-193 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xiafukaiti G |
| Year: |
2019 |
| Journal: |
Mol Cell Biol |
| Title: |
MafB Is Important for Pancreatic β-Cell Maintenance under a MafA-Deficient Condition. |
| Volume: |
39 |
| Issue: |
17 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lin HH |
| Year: |
2024 |
| Journal: |
Nat Commun |
| Title: |
Spint1 disruption in mouse pancreas leads to glucose intolerance and impaired insulin production involving HEPSIN/MAFA. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
10537 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu Q |
| Year: |
2021 |
| Journal: |
Sci Adv |
| Title: |
Astrocytes contribute to pain gating in the spinal cord. |
| Volume: |
7 |
| Issue: |
45 |
| Pages: |
eabi6287 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guo S |
| Year: |
2013 |
| Journal: |
J Clin Invest |
| Title: |
Inactivation of specific β cell transcription factors in type 2 diabetes. |
| Volume: |
123 |
| Issue: |
8 |
| Pages: |
3305-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Abdellatif AM |
| Year: |
2015 |
| Journal: |
Exp Anim |
| Title: |
Role of large MAF transcription factors in the mouse endocrine pancreas. |
| Volume: |
64 |
| Issue: |
3 |
| Pages: |
305-12 |
|
•
•
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| Publication |
| First Author: |
Galloway JR |
| Year: |
2015 |
| Journal: |
Mol Endocrinol |
| Title: |
SSBP3 Interacts With Islet-1 and Ldb1 to Impact Pancreatic β-Cell Target Genes. |
| Volume: |
29 |
| Issue: |
12 |
| Pages: |
1774-86 |
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| Publication |
| First Author: |
ZeRuth GT |
| Year: |
2013 |
| Journal: |
Mol Endocrinol |
| Title: |
The Krüppel-like protein Gli-similar 3 (Glis3) functions as a key regulator of insulin transcription. |
| Volume: |
27 |
| Issue: |
10 |
| Pages: |
1692-705 |
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| Publication |
| First Author: |
Doyle MJ |
| Year: |
2007 |
| Journal: |
Development |
| Title: |
Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet. |
| Volume: |
134 |
| Issue: |
3 |
| Pages: |
515-23 |
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| Publication |
| First Author: |
Kang HS |
| Year: |
2009 |
| Journal: |
Mol Cell Biol |
| Title: |
Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression. |
| Volume: |
29 |
| Issue: |
24 |
| Pages: |
6366-79 |
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| Publication |
| First Author: |
Artner I |
| Year: |
2007 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
MafB is required for islet beta cell maturation. |
| Volume: |
104 |
| Issue: |
10 |
| Pages: |
3853-8 |
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| Publication |
| First Author: |
Wang Y |
| Year: |
2020 |
| Journal: |
Diabetes |
| Title: |
m6A mRNA Methylation Controls Functional Maturation in Neonatal Murine β-Cells. |
| Volume: |
69 |
| Issue: |
8 |
| Pages: |
1708-1722 |
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| Publication |
| First Author: |
Murakami-Kawaguchi S |
| Year: |
2014 |
| Journal: |
Cell Tissue Res |
| Title: |
Expression of Ins1 and Ins2 genes in mouse fetal liver. |
| Volume: |
355 |
| Issue: |
2 |
| Pages: |
303-14 |
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| Publication |
| First Author: |
Ito A |
| Year: |
2022 |
| Journal: |
Dev Neurobiol |
| Title: |
Expression of Maf family proteins in glutamatergic neurons of the mouse olfactory bulb. |
| Volume: |
82 |
| Issue: |
1 |
| Pages: |
77-87 |
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| Publication |
| First Author: |
Paul L |
| Year: |
2016 |
| Journal: |
Diabetes |
| Title: |
Lack of Prox1 Downregulation Disrupts the Expansion and Maturation of Postnatal Murine β-Cells. |
| Volume: |
65 |
| Issue: |
3 |
| Pages: |
687-98 |
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| Publication |
| First Author: |
Conrad E |
| Year: |
2016 |
| Journal: |
Am J Physiol Endocrinol Metab |
| Title: |
The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells. |
| Volume: |
310 |
| Issue: |
1 |
| Pages: |
E91-E102 |
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•
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| Publication |
| First Author: |
Nishimura W |
| Year: |
2008 |
| Journal: |
Dev Biol |
| Title: |
Preferential reduction of beta cells derived from Pax6-MafB pathway in MafB deficient mice. |
| Volume: |
314 |
| Issue: |
2 |
| Pages: |
443-56 |
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| Publication |
| First Author: |
Hu J |
| Year: |
2012 |
| Journal: |
J Neurosci |
| Title: |
c-Maf is required for the development of dorsal horn laminae III/IV neurons and mechanoreceptive DRG axon projections. |
| Volume: |
32 |
| Issue: |
16 |
| Pages: |
5362-73 |
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| Publication |
| First Author: |
Shawki HH |
| Year: |
2018 |
| Journal: |
PLoS One |
| Title: |
MAFB is dispensable for the fetal testis morphogenesis and the maintenance of spermatogenesis in adult mice. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
e0190800 |
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| Publication |
| First Author: |
Plank JL |
| Year: |
2011 |
| Journal: |
Dev Biol |
| Title: |
Influence and timing of arrival of murine neural crest on pancreatic beta cell development and maturation. |
| Volume: |
349 |
| Issue: |
2 |
| Pages: |
321-30 |
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| Publication |
| First Author: |
Dobosz AM |
| Year: |
2022 |
| Journal: |
Mol Metab |
| Title: |
Inhibition of stearoyl-CoA desaturase 1 in the mouse impairs pancreatic islet morphogenesis and promotes loss of β-cell identity and α-cell expansion in the mature pancreas. |
| Volume: |
67 |
|
| Pages: |
101659 |
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| Publication |
| First Author: |
Toren E |
| Year: |
2023 |
| Journal: |
Mol Metab |
| Title: |
The SSBP3 co-regulator is required for glucose homeostasis, pancreatic islet architecture, and beta-cell identity. |
| Volume: |
76 |
|
| Pages: |
101785 |
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| Publication |
| First Author: |
Davidson RK |
| Year: |
2024 |
| Journal: |
Diabetologia |
| Title: |
The SWI/SNF chromatin remodelling complex regulates pancreatic endocrine cell expansion and differentiation in mice in vivo. |
| Volume: |
67 |
| Issue: |
10 |
| Pages: |
2275-2288 |
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•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|