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Search results 1 to 100 out of 352 for Mafk

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0.042s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: Maf transcription factors form a distinct family of the basic leucine zipper (bZip) transcription factors. The Maf family is divided into two subclasses, large Mafs and small Mafs (MafF, MafK []and MafG []). Both subclasses contain leucine-zipper motifs, which allow homodimerisation as well as heterodimerisation with a variety of other bZip proteins. Small Mafs can act as negative regulators of transcription by recruiting transcriptional repressors or by forming homodimers that can then displace active dimers. Small Mafs lack a transactivator domain, but they can also serve as transcriptional activators by dimerising with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites.The small Mafs (MafF, MafG and MafK) appear to be crucial regulators of mammalian gene expression. Small Mafs are also involved in regulating stress response and detoxification pathways [].
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: false
Publication
First Author: Fujiwara KT
Year: 1993
Journal: Oncogene
Title: Two new members of the maf oncogene family, mafK and mafF, encode nuclear b-Zip proteins lacking putative trans-activator domain.
Volume: 8
Issue: 9
Pages: 2371-80
Publication
First Author: Blank V
Year: 1997
Journal: Blood
Title: Human MafG is a functional partner for p45 NF-E2 in activating globin gene expression.
Volume: 89
Issue: 11
Pages: 3925-35
Publication
First Author: Kannan MB
Year: 2012
Journal: Biochim Biophys Acta
Title: The small MAF transcription factors MAFF, MAFG and MAFK: current knowledge and perspectives.
Volume: 1823
Issue: 10
Pages: 1841-6
Publication  
First Author: Hwang YJ
Year: 2013
Journal: Sci Rep
Title: MafK positively regulates NF-κB activity by enhancing CBP-mediated p65 acetylation.
Volume: 3
Pages: 3242
Protein
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: false
Publication
First Author: Igarashi K
Year: 1995
Journal: J Biol Chem
Title: Activity and expression of murine small Maf family protein MafK.
Volume: 270
Issue: 13
Pages: 7615-24
Publication
First Author: Abdellatif AM
Year: 2016
Journal: PLoS One
Title: β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development.
Volume: 11
Issue: 2
Pages: e0150010
Publication
First Author: Motohashi H
Year: 1996
Journal: Genes Cells
Title: Mesodermal- vs. neuronal-specific expression of MafK is elicited by different promoters.
Volume: 1
Issue: 2
Pages: 223-38
Publication
First Author: Andrews NC
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene.
Volume: 90
Issue: 24
Pages: 11488-92
Publication
First Author: Shimohata H
Year: 2006
Journal: Biochem Biophys Res Commun
Title: MafK overexpression in pancreatic beta-cells caused impairment of glucose-stimulated insulin secretion.
Volume: 346
Issue: 3
Pages: 671-80
Publication
First Author: Katsuoka F
Year: 2000
Journal: EMBO J
Title: One enhancer mediates mafK transcriptional activation in both hematopoietic and cardiac muscle cells.
Volume: 19
Issue: 12
Pages: 2980-91
Publication
First Author: Agrawal SA
Year: 2015
Journal: Hum Genet
Title: Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract.
Volume: 134
Issue: 7
Pages: 717-35
Publication
First Author: Töröcsik B
Year: 2002
Journal: J Neurosci
Title: The basic region and leucine zipper transcription factor MafK is a new nerve growth factor-responsive immediate early gene that regulates neurite outgrowth.
Volume: 22
Issue: 20
Pages: 8971-80
GXD Expression    
Probe: MGI:6177470
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190756
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Mafk
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6177470
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190756
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Mafk
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6177470
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190756
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Mafk
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6177470
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190756
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Mafk
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6177470
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190756
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Mafk
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6177470
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190756
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Mafk
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6177470
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190756
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Mafk
Detected: true
Specimen Num: 7
Publication
First Author: Oyake T
Year: 1996
Journal: Mol Cell Biol
Title: Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site.
Volume: 16
Issue: 11
Pages: 6083-95
Publication  
First Author: Patel SD
Year: 2022
Journal: Front Cell Dev Biol
Title: Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects.
Volume: 10
Pages: 981893
Publication
First Author: Itoh K
Year: 1997
Journal: Biochem Biophys Res Commun
Title: An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements.
Volume: 236
Issue: 2
Pages: 313-22
Publication
First Author: Shimohata H
Year: 2009
Journal: Biochem Biophys Res Commun
Title: MafA-deficient and beta cell-specific MafK-overexpressing hybrid transgenic mice develop human-like severe diabetic nephropathy.
Volume: 389
Issue: 2
Pages: 235-40
Publication
First Author: Onodera K
Year: 2000
Journal: EMBO J
Title: Perinatal synthetic lethality and hematopoietic defects in compound mafG::mafK mutant mice.
Volume: 19
Issue: 6
Pages: 1335-45
Publication
First Author: Shavit JA
Year: 1998
Journal: Genes Dev
Title: Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice.
Volume: 12
Issue: 14
Pages: 2164-74
Publication
First Author: Motohashi H
Year: 2000
Journal: Cell
Title: Positive or negative MARE-dependent transcriptional regulation is determined by the abundance of small Maf proteins.
Volume: 103
Issue: 6
Pages: 865-75
Publication
First Author: Igarashi K
Year: 1994
Journal: Nature
Title: Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins.
Volume: 367
Issue: 6463
Pages: 568-72
Publication
First Author: Katsuoka F
Year: 2003
Journal: Mol Cell Biol
Title: Small Maf compound mutants display central nervous system neuronal degeneration, aberrant transcription, and Bach protein mislocalization coincident with myoclonus and abnormal startle response.
Volume: 23
Issue: 4
Pages: 1163-74
Publication
First Author: Katsuoka F
Year: 2005
Journal: Mol Cell Biol
Title: Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes.
Volume: 25
Issue: 18
Pages: 8044-51
Publication
First Author: Murphy P
Year: 2000
Journal: Mech Dev
Title: Expression of the bZIP transcription factor TCF11 and its potential dimerization partners during development.
Volume: 97
Issue: 1-2
Pages: 141-8
Publication
First Author: Onodera K
Year: 1999
Journal: J Biol Chem
Title: Characterization of the murine mafF gene.
Volume: 274
Issue: 30
Pages: 21162-9
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:2656260
Assay Type: Northern blot
Annotation Date: 2003-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2656264
Age: postnatal adult
Image: 6
Specimen Label: brain
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2656260
Assay Type: Northern blot
Annotation Date: 2003-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2656264
Age: postnatal adult
Image: 6
Specimen Label: liver
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2656260
Assay Type: Northern blot
Annotation Date: 2003-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2656264
Age: postnatal adult
Image: 6
Specimen Label: spleen
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2656260
Assay Type: Northern blot
Annotation Date: 2003-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2656264
Age: postnatal adult
Image: 6
Specimen Label: lung
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2656260
Assay Type: Northern blot
Annotation Date: 2003-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2656264
Age: postnatal adult
Image: 6
Specimen Label: kidney
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2656260
Assay Type: Northern blot
Annotation Date: 2003-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2656264
Age: postnatal adult
Image: 6
Specimen Label: heart
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2656260
Assay Type: Northern blot
Annotation Date: 2003-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2656264
Age: postnatal adult
Image: 6
Specimen Label: skeletal muscle
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:2656260
Assay Type: Northern blot
Annotation Date: 2003-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Stage: TS20
Assay Id: MGI:2656267
Age: embryonic day 12.0
Image: 6
Specimen Label: fetus 12
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2656260
Assay Type: Northern blot
Annotation Date: 2003-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:2656267
Age: embryonic day 14.0
Image: 6
Specimen Label: fetus 14
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2656260
Assay Type: Northern blot
Annotation Date: 2003-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:2656267
Age: embryonic day 16.0
Image: 6
Specimen Label: fetus 16
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2656260
Assay Type: Northern blot
Annotation Date: 2003-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:2656267
Age: postnatal newborn
Image: 6
Specimen Label: newborn 0
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2656260
Assay Type: Northern blot
Annotation Date: 2003-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2656267
Age: postnatal day 7
Image: 6
Specimen Label: newborn 7
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2656260
Assay Type: Northern blot
Annotation Date: 2003-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2656267
Age: postnatal day 14
Image: 6
Specimen Label: newborn 14
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2663438
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2663442
Age: postnatal adult
Image: 7
Specimen Label: Brain
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2663438
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:2663442
Age: postnatal adult
Image: 7
Specimen Label: Thymus
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2663438
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2663442
Age: postnatal adult
Image: 7
Specimen Label: Lung
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2663438
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2663442
Age: postnatal adult
Image: 7
Specimen Label: Liver
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2663438
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2663442
Age: postnatal adult
Image: 7
Specimen Label: Spleen
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2663438
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:2663442
Age: postnatal adult
Image: 7
Specimen Label: Intestine
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2663438
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2663442
Age: postnatal adult
Image: 7
Specimen Label: Kidney
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:2663438
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2663442
Age: postnatal adult
Image: 7
Specimen Label: Heart
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:2663438
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:2663442
Age: postnatal adult
Image: 7
Specimen Label: Muscle
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:2663438
Assay Type: RT-PCR
Annotation Date: 2003-06-23
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:2663442
Age: postnatal adult
Image: 7
Specimen Label: Ovary
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:2673616
Assay Type: RT-PCR
Annotation Date: 2003-09-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684623
Stage: TS23
Assay Id: MGI:2673618
Age: embryonic day 15.5
Image: 2
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:2673616
Assay Type: RT-PCR
Annotation Date: 2003-09-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684623
Stage: TS23
Assay Id: MGI:2673618
Age: embryonic day 15.5
Image: 2
Specimen Label: +/-
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2673616
Assay Type: RT-PCR
Annotation Date: 2003-09-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684623
Stage: TS23
Assay Id: MGI:2673618
Age: embryonic day 15.5
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:2684454
Assay Type: RT-PCR
Annotation Date: 2004-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:2684456
Age: embryonic day 9.5
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2684454
Assay Type: RT-PCR
Annotation Date: 2004-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:2684456
Age: embryonic day 9.5
Specimen Label: None
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2684472
Assay Type: Western blot
Annotation Date: 2004-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:2684473
Age: postnatal adult
Specimen Label: mafG-/-
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2684472
Assay Type: Western blot
Annotation Date: 2004-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:2684473
Age: postnatal adult
Specimen Label: wild type
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3815879
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816683
Age: postnatal
Specimen Label: Metaphase II
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3815879
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816683
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3815879
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816683
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3815879
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816683
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3815879
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816683
Age: embryonic day 3.0
Specimen Label: Morula
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3815879
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3816683
Age: embryonic day 3.5
Specimen Label: E3.5 blastocyst
Detected: true
Specimen Num: 6