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Search results 1 to 100 out of 149 for Map1a

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0.06s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Domain
Type: Family
Description: MAP1 is one of the first described microtubule-associated proteins (MAPs). It was discovered through its association with tubulin, and was later resolved into three distinct proteins: MAP1A, MAP1B (also called MAP5) and MAP1C. MAP1A and MAP1B are structurally related and share light chains with each other, and MAP1C was later shown to be the heavy chain of brain cytoplasmic dynein [].MAP1A is a long, rod-shaped protein that is made up of a large heavy chain and three light chains, LC1, LC2 and LC3. Light chain binding appears to regulate the activity of MAP1A and MAP1B []. MAP1A binds to and stabilises microtubules and can promote microtubule assembly []. It is expressed in mature neurons and may serve a key function in synaptic plasticity [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Nakayama A
Year: 2003
Journal: J Biol Chem
Title: Role for RFX transcription factors in non-neuronal cell-specific inactivation of the microtubule-associated protein MAP1A promoter.
Volume: 278
Issue: 1
Pages: 233-40
Publication
First Author: Fuhrmann-Stroissnigg H
Year: 2012
Journal: PLoS One
Title: The light chains of microtubule-associated proteins MAP1A and MAP1B interact with α1-syntrophin in the central and peripheral nervous system.
Volume: 7
Issue: 11
Pages: e49722
Publication
First Author: Schoenfeld TA
Year: 1989
Journal: J Neurosci
Title: MAP 1A and MAP 1B are structurally related microtubule associated proteins with distinct developmental patterns in the CNS.
Volume: 9
Issue: 5
Pages: 1712-30
Publication
First Author: Noiges R
Year: 2002
Journal: J Neurosci
Title: Microtubule-associated protein 1A (MAP1A) and MAP1B: light chains determine distinct functional properties.
Volume: 22
Issue: 6
Pages: 2106-14
Publication
First Author: Pedrotti B
Year: 1994
Journal: Biochemistry
Title: Purified native microtubule associated protein MAP1A: kinetics of microtubule assembly and MAP1A/tubulin stoichiometry.
Volume: 33
Issue: 41
Pages: 12463-70
Publication
First Author: Clemmensen C
Year: 2012
Journal: Cell Mol Neurobiol
Title: The microtubule-associated protein 1A (MAP1A) is an early molecular target of soluble Aβ-peptide.
Volume: 32
Issue: 4
Pages: 561-6
Publication
First Author: Szebenyi G
Year: 2005
Journal: Curr Biol
Title: Activity-driven dendritic remodeling requires microtubule-associated protein 1A.
Volume: 15
Issue: 20
Pages: 1820-6
Protein
Organism: Mus musculus
Length: 2776  
Fragment?: false
Protein
Organism: Mus musculus
Length: 3014  
Fragment?: false
Publication
First Author: Nakayama A
Year: 2001
Journal: Biochim Biophys Acta
Title: Characterization of two promoters that regulate alternative transcripts in the microtubule-associated protein (MAP) 1A gene.
Volume: 1518
Issue: 3
Pages: 260-6
Publication
First Author: Xia Y
Year: 2017
Journal: Biochem J
Title: Structure of the PSD-95/MAP1A complex reveals a unique target recognition mode of the MAGUK GK domain.
Volume: 474
Issue: 16
Pages: 2817-2828
Publication
First Author: Edelmann W
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Neuronal abnormalities in microtubule-associated protein 1B mutant mice.
Volume: 93
Issue: 3
Pages: 1270-5
Publication
First Author: Liu Y
Year: 2015
Journal: J Neurosci
Title: Mutations in the microtubule-associated protein 1A (Map1a) gene cause Purkinje cell degeneration.
Volume: 35
Issue: 11
Pages: 4587-98
Publication  
First Author: Grossman GH
Year: 2014
Journal: Adv Exp Med Biol
Title: Interaction of tubby-like protein-1 (Tulp1) and microtubule-associated protein (MAP) 1A and MAP1B in the mouse retina.
Volume: 801
Pages: 511-8
Publication
First Author: Takei Y
Year: 2015
Journal: J Neurosci
Title: Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A.
Volume: 35
Issue: 47
Pages: 15539-54
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:2652439
Assay Type: Western blot
Annotation Date: 2003-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Stage: TS26
Assay Id: MGI:2652486
Age: embryonic day 19.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2652439
Assay Type: Western blot
Annotation Date: 2003-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Stage: TS26
Assay Id: MGI:2652486
Age: embryonic day 19.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2652439
Assay Type: Western blot
Annotation Date: 2003-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Stage: TS26
Assay Id: MGI:2652486
Age: embryonic day 19.0
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6358509
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6358634
Age: embryonic day 18.5
Image: 9Db
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6358509
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6358634
Age: embryonic day 18.5
Image: 9De
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6358509
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6358634
Age: embryonic day 18.5
Image: 9Dh
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6358509
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6358634
Age: embryonic day 18.5
Image: 9Dk
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6358509
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6358634
Age: embryonic day 18.5
Image: 9Db
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6358509
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6358634
Age: embryonic day 18.5
Image: 9De
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6358509
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6358634
Age: embryonic day 18.5
Image: 9Dh
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6358509
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6358634
Age: embryonic day 18.5
Image: 9Dk
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6358509
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6358634
Age: embryonic day 18.5
Image: 9Db
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6358509
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6358634
Age: embryonic day 18.5
Image: 9De
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6358509
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6358634
Age: embryonic day 18.5
Image: 9Dh
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6358509
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6358634
Age: embryonic day 18.5
Image: 9Dk
Detected: true
Specimen Num: 4
Publication
First Author: Fang Q
Year: 2011
Journal: Genetics
Title: A modifier gene alleviates hypothyroidism-induced hearing impairment in Pou1f1dw dwarf mice.
Volume: 189
Issue: 2
Pages: 665-73
Publication
First Author: Ikeda A
Year: 1999
Journal: Hum Mol Genet
Title: Genetic modification of hearing in tubby mice: evidence for the existence of a major gene (moth1) which protects tubby mice from hearing loss.
Volume: 8
Issue: 9
Pages: 1761-7
Publication
First Author: Takei Y
Year: 1997
Journal: J Cell Biol
Title: Delayed development of nervous system in mice homozygous for disrupted microtubule-associated protein 1B (MAP1B) gene.
Volume: 137
Issue: 7
Pages: 1615-26
Publication
First Author: Garner CC
Year: 1990
Journal: J Neurochem
Title: Molecular cloning of microtubule-associated protein 1 (MAP1A) and microtubule-associated protein 5 (MAP1B): identification of distinct genes and their differential expression in developing brain.
Volume: 55
Issue: 1
Pages: 146-54
Publication
First Author: Kutschera W
Year: 1998
Journal: Genomics
Title: The mouse and rat MAP1B genes: genomic organization and alternative transcription.
Volume: 49
Issue: 3
Pages: 430-6
Publication
First Author: Ikeda A
Year: 2002
Journal: Nat Genet
Title: Microtubule-associated protein 1A is a modifier of tubby hearing (moth1).
Volume: 30
Issue: 4
Pages: 401-5
Publication
First Author: Maddox DM
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: An allele of microtubule-associated protein 1A (Mtap1a) reduces photoreceptor degeneration in Tulp1 and Tub Mutant Mice.
Volume: 53
Issue: 3
Pages: 1663-9
Publication
First Author: Noguchi Y
Year: 2006
Journal: Genetics
Title: Multiple quantitative trait loci modify cochlear hair cell degeneration in the Beethoven (Tmc1Bth) mouse model of progressive hearing loss DFNA36.
Volume: 173
Issue: 4
Pages: 2111-9
Publication
First Author: Suda Y
Year: 2010
Journal: Development
Title: The same enhancer regulates the earliest Emx2 expression in caudal forebrain primordium, subsequent expression in dorsal telencephalon and later expression in the cortical ventricular zone.
Volume: 137
Issue: 17
Pages: 2939-49
Publication
First Author: Komatsu M
Year: 2007
Journal: Cell
Title: Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.
Volume: 131
Issue: 6
Pages: 1149-63
Publication
First Author: González-Billault C
Year: 2000
Journal: Mol Cell Neurosci
Title: Perinatal lethality of microtubule-associated protein 1B-deficient mice expressing alternative isoforms of the protein at low levels.
Volume: 16
Issue: 4
Pages: 408-21
Publication
First Author: Faussone-Pellegrini MS
Year: 1999
Journal: Anat Embryol (Berl)
Title: The cytoskeleton of the myenteric neurons during murine embryonic life.
Volume: 199
Issue: 5
Pages: 459-69
Publication
First Author: Aoki K
Year: 1995
Journal: Anat Embryol (Berl)
Title: Differential expression of N-CAM, vimentin and MAP1B during initial pathfinding of olfactory receptor neurons in the mouse embryo.
Volume: 192
Issue: 3
Pages: 211-20
Publication
First Author: Tretyakova I
Year: 2005
Journal: J Biol Chem
Title: Nuclear export factor family protein participates in cytoplasmic mRNA trafficking.
Volume: 280
Issue: 36
Pages: 31981-90
Publication
First Author: Ikegami K
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Loss of alpha-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function.
Volume: 104
Issue: 9
Pages: 3213-8
Publication  
First Author: Yu Z
Year: 2012
Journal: Neuroscience
Title: Identification of neuroglobin-interacting proteins using yeast two-hybrid screening.
Volume: 200
Pages: 99-105
Publication
First Author: Chakraborti A
Year: 1992
Journal: Mouse Genome
Title: Microtubule-associated protein genes (Mtap-1, Mtap-2, Mtap-5) map to mouse chromosomes 1, 2 and 13
Volume: 90
Issue: 4
Pages: 679-81
Publication
First Author: Johnson KR
Year: 2006
Journal: Brain Res
Title: Strain background effects and genetic modifiers of hearing in mice.
Volume: 1091
Issue: 1
Pages: 79-88
Publication
First Author: Zheng M
Year: 2017
Journal: FASEB J
Title: Tau haploinsufficiency causes prenatal loss of dopaminergic neurons in the ventral tegmental area and reduction of transcription factor orthodenticle homeobox 2 expression.
Volume: 31
Issue: 8
Pages: 3349-3358
Publication
First Author: Chiannilkulchai N
Year: 1995
Journal: Hum Mol Genet
Title: A primary expression map of the chromosome 15q15 region containing the recessive form of limb-girdle muscular dystrophy (LGMD2A) gene.
Volume: 4
Issue: 4
Pages: 717-25
Publication
First Author: Nadeau JH
Year: 2003
Journal: Curr Opin Genet Dev
Title: Modifier genes and protective alleles in humans and mice.
Volume: 13
Issue: 3
Pages: 290-5
Publication
First Author: Kozak CA
Year: 1995
Journal: Genomics
Title: Genomic cloning of mouse MIF (macrophage inhibitory factor) and genetic mapping of the human and mouse expressed gene and nine mouse pseudogenes.
Volume: 27
Issue: 3
Pages: 405-11
Publication
First Author: Cossette SM
Year: 2014
Journal: Biol Open
Title: Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism.
Volume: 4
Issue: 1
Pages: 48-61
Publication
First Author: Zuberi AR
Year: 1996
Journal: Genomics
Title: A genetic linkage map of mouse chromosome 2 extending from thrombospondin to paired box gene 1, including the H3 minor histocompatibility complex.
Volume: 33
Issue: 1
Pages: 75-84
Publication
First Author: Sullivan SL
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: The chromosomal distribution of mouse odorant receptor genes.
Volume: 93
Issue: 2
Pages: 884-8
Publication
First Author: Lyu MS
Year: 1996
Journal: Mamm Genome
Title: Genetic mapping of the human and mouse phospholipase C genes.
Volume: 7
Issue: 7
Pages: 501-4
Publication
First Author: Munton RP
Year: 2007
Journal: Mol Cell Proteomics
Title: Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.
Volume: 6
Issue: 2
Pages: 283-93
Publication
First Author: Kozak CA
Year: 1999
Journal: Mamm Genome
Title: Identification and genetic mapping of differentially expressed genes in mice differing at the If1 interferon regulatory locus.
Volume: 10
Issue: 9
Pages: 853-7
Publication        
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.