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Search results 1 to 100 out of 470 for Map1b

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0.431s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Rattus norvegicus
Protein Domain
Type: Family
Description: MAP1-family proteins are microtubule-associated proteins (MAPs) that bind along the microtubule lattice. Mammalian genomes usually contain three family members, MAP1A, MAP1B and MAP1S. Only one family member, Futsch, is found in Drosophila.Human MAP1A and MAP1B, are predominantly expressed in neurons, where they are thought to be important in the formation and development of axons and dendrites [, ]. Human MAP1A and MAP1B stabilise microtubules and interact with other cellular components, including filamentous actin and signalling proteins. The activity of MAP1A and MAP1B is controlled by upstream signalling mechanisms, including the MAP kinase and glycogen synthase kinase-3 beta pathways []. This entry represent MAP1B. It may bind to at least two tubulin subunits in the polymer. This bridging of subunits might be involved in nucleating microtubule polymerisation and in stabilising microtubules []. Besides its microtubule regulation functions, MAP1B also acts as a signalling protein involved in normal physiology and pathological conditions in the nervous system [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Villarroel-Campos D
Year: 2014
Journal: Dev Neurobiol
Title: The MAP1B case: an old MAP that is new again.
Volume: 74
Issue: 10
Pages: 953-71
Publication
First Author: Gonzalez-Billault C
Year: 2001
Journal: Mol Biol Cell
Title: Evidence for the role of MAP1B in axon formation.
Volume: 12
Issue: 7
Pages: 2087-98
Publication
First Author: González-Billault C
Year: 2005
Journal: Cereb Cortex
Title: A role of MAP1B in Reelin-dependent neuronal migration.
Volume: 15
Issue: 8
Pages: 1134-45
Publication
First Author: Jiménez-Mateos EM
Year: 2006
Journal: Biochem J
Title: Role of MAP1B in axonal retrograde transport of mitochondria.
Volume: 397
Issue: 1
Pages: 53-9
Publication
First Author: Montenegro-Venegas C
Year: 2010
Journal: Mol Biol Cell
Title: MAP1B regulates axonal development by modulating Rho-GTPase Rac1 activity.
Volume: 21
Issue: 20
Pages: 3518-28
Publication
First Author: Chen YL
Year: 2013
Journal: J Neurosci
Title: Modulation of mGluR-dependent MAP1B translation and AMPA receptor endocytosis by microRNA miR-146a-5p.
Volume: 33
Issue: 21
Pages: 9013-20
Publication
First Author: Kutschera W
Year: 1998
Journal: Genomics
Title: The mouse and rat MAP1B genes: genomic organization and alternative transcription.
Volume: 49
Issue: 3
Pages: 430-6
Publication
First Author: Palenzuela R
Year: 2017
Journal: J Neurosci
Title: MAP1B Light Chain Modulates Synaptic Transmission via AMPA Receptor Intracellular Trapping.
Volume: 37
Issue: 41
Pages: 9945-9963
Publication
First Author: Noble M
Year: 1989
Journal: J Cell Biol
Title: The microtubule binding domain of microtubule-associated protein MAP1B contains a repeated sequence motif unrelated to that of MAP2 and tau.
Volume: 109
Issue: 6 Pt 2
Pages: 3367-76
Publication
First Author: Utreras E
Year: 2008
Journal: Dev Neurosci
Title: Microtubule-associated protein 1B interaction with tubulin tyrosine ligase contributes to the control of microtubule tyrosination.
Volume: 30
Issue: 1-3
Pages: 200-10
Publication
First Author: Tortosa E
Year: 2011
Journal: J Biol Chem
Title: Microtubule-associated protein 1B (MAP1B) is required for dendritic spine development and synaptic maturation.
Volume: 286
Issue: 47
Pages: 40638-48
Publication
First Author: Pangratz-Fuehrer S
Year: 2005
Journal: Behav Brain Res
Title: Mice deficient in microtubule-associated protein MAP1B show a distinct behavioral phenotype and altered retina function.
Volume: 164
Issue: 2
Pages: 188-96
Publication
First Author: Eriksson M
Year: 2010
Journal: Neurosci Lett
Title: MAP1B binds to the NMDA receptor subunit NR3A and affects NR3A protein concentrations.
Volume: 475
Issue: 1
Pages: 33-7
Protein
Organism: Mus musculus
Length: 724  
Fragment?: true
Protein
Organism: Mus musculus
Length: 377  
Fragment?: true
Protein
Organism: Mus musculus
Length: 236  
Fragment?: false
Protein
Organism: Mus musculus
Length: 396  
Fragment?: true
Protein
Organism: Mus musculus
Length: 324  
Fragment?: true
Protein
Organism: Mus musculus
Length: 691  
Fragment?: true
Protein
Organism: Mus musculus
Length: 61  
Fragment?: false
Protein
Organism: Mus musculus
Length: 528  
Fragment?: true
Publication
First Author: Halpain S
Year: 2006
Journal: Genome Biol
Title: The MAP1 family of microtubule-associated proteins.
Volume: 7
Issue: 6
Pages: 224
Publication
First Author: Tymanskyj SR
Year: 2012
Journal: Mol Cell Neurosci
Title: MAP1B enhances microtubule assembly rates and axon extension rates in developing neurons.
Volume: 49
Issue: 2
Pages: 110-9
Protein
Organism: Mus musculus
Length: 2464  
Fragment?: false
Protein
Organism: Mus musculus
Length: 2464  
Fragment?: false
Publication
First Author: Bouquet C
Year: 2007
Journal: Mol Cell Neurosci
Title: MAP1B coordinates microtubule and actin filament remodeling in adult mouse Schwann cell tips and DRG neuron growth cones.
Volume: 36
Issue: 2
Pages: 235-47
Publication
First Author: Takei Y
Year: 2000
Journal: J Cell Biol
Title: Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes.
Volume: 150
Issue: 5
Pages: 989-1000
Publication
First Author: Del Río JA
Year: 2004
Journal: Curr Biol
Title: MAP1B is required for Netrin 1 signaling in neuronal migration and axonal guidance.
Volume: 14
Issue: 10
Pages: 840-50
Publication
First Author: Tortosa E
Year: 2013
Journal: EMBO J
Title: MAP1B regulates microtubule dynamics by sequestering EB1/3 in the cytosol of developing neuronal cells.
Volume: 32
Issue: 9
Pages: 1293-306
Publication  
First Author: Grossman GH
Year: 2014
Journal: Adv Exp Med Biol
Title: Interaction of tubby-like protein-1 (Tulp1) and microtubule-associated protein (MAP) 1A and MAP1B in the mouse retina.
Volume: 801
Pages: 511-8
Publication
First Author: Teng J
Year: 2001
Journal: J Cell Biol
Title: Synergistic effects of MAP2 and MAP1B knockout in neuronal migration, dendritic outgrowth, and microtubule organization.
Volume: 155
Issue: 1
Pages: 65-76
Publication
First Author: Meixner A
Year: 2000
Journal: J Cell Biol
Title: MAP1B is required for axon guidance and Is involved in the development of the central and peripheral nervous system.
Volume: 151
Issue: 6
Pages: 1169-78
Publication
First Author: Aoki K
Year: 1995
Journal: Anat Embryol (Berl)
Title: Differential expression of N-CAM, vimentin and MAP1B during initial pathfinding of olfactory receptor neurons in the mouse embryo.
Volume: 192
Issue: 3
Pages: 211-20
Publication
First Author: Fuhrmann-Stroissnigg H
Year: 2012
Journal: PLoS One
Title: The light chains of microtubule-associated proteins MAP1A and MAP1B interact with α1-syntrophin in the central and peripheral nervous system.
Volume: 7
Issue: 11
Pages: e49722
Publication
First Author: Meixner A
Year: 1999
Journal: Biochim Biophys Acta
Title: Analysis of the mouse MAP1B gene identifies a highly conserved 4.3 kb 3' untranslated region and provides evidence against the proposed structure of DBI-1 cDNA.
Volume: 1445
Issue: 3
Pages: 345-50
Publication
First Author: Stroissnigg H
Year: 2007
Journal: Nat Cell Biol
Title: S-nitrosylation of microtubule-associated protein 1B mediates nitric-oxide-induced axon retraction.
Volume: 9
Issue: 9
Pages: 1035-45
Publication
First Author: Liu D
Year: 1996
Journal: Gene
Title: Isolation and sequencing of the 5' end of the rat microtubule-associated protein (MAP1B)-encoding cDNA.
Volume: 171
Issue: 2
Pages: 307-8
Publication
First Author: Meli R
Year: 2015
Journal: PLoS One
Title: Repulsive axon guidance by Draxin is mediated by protein Kinase B (Akt), glycogen synthase kinase-3β (GSK-3β) and microtubule-associated protein 1B.
Volume: 10
Issue: 3
Pages: e0119524
Publication
First Author: Gödel M
Year: 2015
Journal: PLoS One
Title: Microtubule Associated Protein 1b (MAP1B) Is a Marker of the Microtubular Cytoskeleton in Podocytes but Is Not Essential for the Function of the Kidney Filtration Barrier in Mice.
Volume: 10
Issue: 10
Pages: e0140116
Publication
First Author: Bouquet C
Year: 2004
Journal: J Neurosci
Title: Microtubule-associated protein 1B controls directionality of growth cone migration and axonal branching in regeneration of adult dorsal root ganglia neurons.
Volume: 24
Issue: 32
Pages: 7204-13
Publication
First Author: Opal P
Year: 2003
Journal: J Biol Chem
Title: Mapmodulin/leucine-rich acidic nuclear protein binds the light chain of microtubule-associated protein 1B and modulates neuritogenesis.
Volume: 278
Issue: 36
Pages: 34691-9
Publication
First Author: Ryan SD
Year: 2012
Journal: J Cell Biol
Title: Microtubule stability, Golgi organization, and transport flux require dystonin-a2-MAP1B interaction.
Volume: 196
Issue: 6
Pages: 727-42
Publication
First Author: Jiménez-Mateos EM
Year: 2005
Journal: J Neurosci Res
Title: End binding protein-1 (EB1) complements microtubule-associated protein-1B during axonogenesis.
Volume: 80
Issue: 3
Pages: 350-9
Publication
First Author: Hatta T
Year: 2018
Journal: Sci Rep
Title: Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B.
Volume: 8
Issue: 1
Pages: 16756
Publication
First Author: Villarroel-Campos D
Year: 2016
Journal: J Neurosci
Title: Rab35 Functions in Axon Elongation Are Regulated by P53-Related Protein Kinase in a Mechanism That Involves Rab35 Protein Degradation and the Microtubule-Associated Protein 1B.
Volume: 36
Issue: 27
Pages: 7298-313
Publication
First Author: González-Billault C
Year: 2002
Journal: J Neurosci Res
Title: Participation of structural microtubule-associated proteins (MAPs) in the development of neuronal polarity.
Volume: 67
Issue: 6
Pages: 713-9
Publication  
First Author: Barnat M
Year: 2016
Journal: Mol Cell Neurosci
Title: The GSK3-MAP1B pathway controls neurite branching and microtubule dynamics.
Volume: 72
Pages: 9-21
Publication
First Author: Takei Y
Year: 1997
Journal: J Cell Biol
Title: Delayed development of nervous system in mice homozygous for disrupted microtubule-associated protein 1B (MAP1B) gene.
Volume: 137
Issue: 7
Pages: 1615-26
Publication
First Author: Edelmann W
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Neuronal abnormalities in microtubule-associated protein 1B mutant mice.
Volume: 93
Issue: 3
Pages: 1270-5
Publication
First Author: O'Brien JE
Year: 2012
Journal: J Biol Chem
Title: Interaction of voltage-gated sodium channel Nav1.6 (SCN8A) with microtubule-associated protein Map1b.
Volume: 287
Issue: 22
Pages: 18459-66
Publication
First Author: Feltrin D
Year: 2012
Journal: PLoS Biol
Title: Growth cone MKK7 mRNA targeting regulates MAP1b-dependent microtubule bundling to control neurite elongation.
Volume: 10
Issue: 12
Pages: e1001439
Publication
First Author: Lu R
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development.
Volume: 101
Issue: 42
Pages: 15201-6
Publication
First Author: Cheng L
Year: 2014
Journal: Neuron
Title: Human CFEOM1 mutations attenuate KIF21A autoinhibition and cause oculomotor axon stalling.
Volume: 82
Issue: 2
Pages: 334-49
Publication
First Author: Benoist M
Year: 2013
Journal: EMBO J
Title: MAP1B-dependent Rac activation is required for AMPA receptor endocytosis during long-term depression.
Volume: 32
Issue: 16
Pages: 2287-99
Publication
First Author: Barnat M
Year: 2010
Journal: J Neurosci
Title: Distinct roles of c-Jun N-terminal kinase isoforms in neurite initiation and elongation during axonal regeneration.
Volume: 30
Issue: 23
Pages: 7804-16
Publication
First Author: Wang QJ
Year: 2006
Journal: J Neurosci
Title: Induction of autophagy in axonal dystrophy and degeneration.
Volume: 26
Issue: 31
Pages: 8057-68
Publication
First Author: Scharf JM
Year: 1996
Journal: Genomics
Title: The mouse region syntenic for human spinal muscular atrophy lies within the Lgn1 critical interval and contains multiple copies of Naip exon 5.
Volume: 38
Issue: 3
Pages: 405-17
Publication
First Author: González-Billault C
Year: 2000
Journal: Mol Cell Neurosci
Title: Perinatal lethality of microtubule-associated protein 1B-deficient mice expressing alternative isoforms of the protein at low levels.
Volume: 16
Issue: 4
Pages: 408-21
Publication
First Author: Tretyakova I
Year: 2005
Journal: J Biol Chem
Title: Nuclear export factor family protein participates in cytoplasmic mRNA trafficking.
Volume: 280
Issue: 36
Pages: 31981-90
Publication
First Author: Armentano M
Year: 2006
Journal: Development
Title: COUP-TFI is required for the formation of commissural projections in the forebrain by regulating axonal growth.
Volume: 133
Issue: 21
Pages: 4151-62
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Durkin AS
Year: 1994
Journal: Cytogenet Cell Genet
Title: Chromosome assignment of human brain expressed sequence tags (ESTs) by analyzing fluorescently labeled PCR products from hybrid cell panels.
Volume: 65
Issue: 1-2
Pages: 86-91
Publication
First Author: Cheng A
Year: 1999
Journal: Brain Res Dev Brain Res
Title: MAP5 expression in proliferating neuroblasts.
Volume: 113
Issue: 1-2
Pages: 107-13
GXD Expression      
Probe: MGI:6209728
Assay Type: RT-PCR
Annotation Date: 2018-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6214914
Age: postnatal day 15
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6209728
Assay Type: RT-PCR
Annotation Date: 2018-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6209846
Age: postnatal day 7
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2652566
Assay Type: Western blot
Annotation Date: 2003-03-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:2652571
Age: postnatal newborn
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:2652566
Assay Type: Western blot
Annotation Date: 2003-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:2652571
Age: postnatal newborn
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2652566
Assay Type: Western blot
Annotation Date: 2003-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:2652571
Age: postnatal newborn
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2652442
Assay Type: Western blot
Annotation Date: 2003-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:2652482
Age: postnatal newborn
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2652442
Assay Type: Western blot
Annotation Date: 2003-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:2652482
Age: postnatal newborn
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2652442
Assay Type: Western blot
Annotation Date: 2003-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:2652482
Age: postnatal newborn
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2652460
Assay Type: Western blot
Annotation Date: 2003-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:2652481
Age: postnatal newborn
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2652460
Assay Type: Western blot
Annotation Date: 2003-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:2652481
Age: postnatal newborn
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2652460
Assay Type: Western blot
Annotation Date: 2003-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:2652481
Age: postnatal newborn
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2652459
Assay Type: Western blot
Annotation Date: 2003-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:2652480
Age: postnatal newborn
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2652459
Assay Type: Western blot
Annotation Date: 2003-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:2652480
Age: postnatal newborn
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2652459
Assay Type: Western blot
Annotation Date: 2003-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:2652480
Age: postnatal newborn
Detected: true
Specimen Num: 1