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Search results 1 to 100 out of 519 for Map2k1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Bissonauth V
Year: 2006
Journal: Development
Title: Requirement for Map2k1 (Mek1) in extra-embryonic ectoderm during placentogenesis.
Volume: 133
Issue: 17
Pages: 3429-40
Publication
First Author: Nadeau V
Year: 2009
Journal: Development
Title: Map2k1 and Map2k2 genes contribute to the normal development of syncytiotrophoblasts during placentation.
Volume: 136
Issue: 8
Pages: 1363-74
Publication
First Author: Ishii K
Year: 2012
Journal: Development
Title: FGF2 mediates mouse spermatogonial stem cell self-renewal via upregulation of Etv5 and Bcl6b through MAP2K1 activation.
Volume: 139
Issue: 10
Pages: 1734-43
Publication
First Author: Bueno OF
Year: 2000
Journal: EMBO J
Title: The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice.
Volume: 19
Issue: 23
Pages: 6341-50
Publication
First Author: Maejima Y
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Constitutively active MEK1 rescues cardiac dysfunction caused by overexpressed GSK-3α during aging and hemodynamic pressure overload.
Volume: 303
Issue: 8
Pages: H979-88
Publication
First Author: Catalanotti F
Year: 2009
Journal: Nat Struct Mol Biol
Title: A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal.
Volume: 16
Issue: 3
Pages: 294-303
Publication    
First Author: Kim JM
Year: 2022
Journal: Elife
Title: Biphasic regulation of osteoblast development via the ERK MAPK-mTOR pathway.
Volume: 11
Publication
First Author: Nadeau V
Year: 2014
Journal: Development
Title: Essential role of the ERK/MAPK pathway in blood-placental barrier formation.
Volume: 141
Issue: 14
Pages: 2825-37
Publication
First Author: Aoidi R
Year: 2016
Journal: Sci Signal
Title: Functional redundancy of the kinases MEK1 and MEK2: Rescue of the Mek1 mutant phenotype by Mek2 knock-in reveals a protein threshold effect.
Volume: 9
Issue: 412
Pages: ra9
Publication
First Author: Krenz M
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Role of ERK1/2 signaling in congenital valve malformations in Noonan syndrome.
Volume: 105
Issue: 48
Pages: 18930-5
Publication
First Author: Holter MC
Year: 2021
Journal: Cereb Cortex
Title: Hyperactive MEK1 Signaling in Cortical GABAergic Neurons Promotes Embryonic Parvalbumin Neuron Loss and Defects in Behavioral Inhibition.
Volume: 31
Issue: 6
Pages: 3064-3081
Publication  
First Author: Aoidi R
Year: 2018
Journal: Dis Model Mech
Title: Mek1Y130C mice recapitulate aspects of human cardio-facio-cutaneous syndrome.
Volume: 11
Issue: 3
Publication    
First Author: Xing L
Year: 2016
Journal: Elife
Title: Layer specific and general requirements for ERK/MAPK signaling in the developing neocortex.
Volume: 5
Publication
First Author: Li X
Year: 2012
Journal: Neuron
Title: MEK Is a Key Regulator of Gliogenesis in the Developing Brain.
Volume: 75
Issue: 6
Pages: 1035-50
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Crews CM
Year: 1992
Journal: Science
Title: The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product.
Volume: 258
Issue: 5081
Pages: 478-80
Publication
First Author: Baumgartner C
Year: 2018
Journal: Cell Stem Cell
Title: An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion.
Volume: 22
Issue: 6
Pages: 879-892.e6
Publication
First Author: Shneider BL
Year: 2021
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Constitutive activation of mitogen-activated protein kinase kinase (MEK1) in ileal enterocytes leads to dysplasia and a predisposition to cancer.
Volume: 320
Issue: 3
Pages: G366-G379
Publication
First Author: Bluhm B
Year: 2017
Journal: Development
Title: miR-322 stabilizes MEK1 expression to inhibit RAF/MEK/ERK pathway activation in cartilage.
Volume: 144
Issue: 19
Pages: 3562-3577
Publication
First Author: Hobbs RM
Year: 2004
Journal: J Invest Dermatol
Title: Expression of activated MEK1 in differentiating epidermal cells is sufficient to generate hyperproliferative and inflammatory skin lesions.
Volume: 123
Issue: 3
Pages: 503-15
Publication
First Author: Gong X
Year: 2001
Journal: Invest Ophthalmol Vis Sci
Title: Development of cataractous macrophthalmia in mice expressing an active MEK1 in the lens.
Volume: 42
Issue: 3
Pages: 539-48
Publication
First Author: Sommer A
Year: 2000
Journal: FEBS Lett
Title: Synergistic activation of the mkp-1 gene by protein kinase A signaling and USF, but not c-Myc.
Volume: 474
Issue: 2-3
Pages: 146-50
Publication
First Author: Emslie EA
Year: 1994
Journal: Hum Genet
Title: The CL100 gene, which encodes a dual specificity (Tyr/Thr) MAP kinase phosphatase, is highly conserved and maps to human chromosome 5q34.
Volume: 93
Issue: 5
Pages: 513-6
Publication
First Author: Druey KM
Year: 1996
Journal: Nature
Title: Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family.
Volume: 379
Issue: 6567
Pages: 742-6
Publication
First Author: Cano E
Year: 1996
Journal: Oncogene
Title: Identification of anisomycin-activated kinases p45 and p55 in murine cells as MAPKAP kinase-2.
Volume: 12
Issue: 4
Pages: 805-12
Publication
First Author: Kornhauser JM
Year: 1997
Journal: Neuron
Title: A kinase to remember: dual roles for MAP kinase in long-term memory.
Volume: 18
Issue: 6
Pages: 839-42
Publication
First Author: Bloom MW
Year: 2006
Journal: Anat Rec A Discov Mol Cell Evol Biol
Title: Aspects of achondroplasia in the skulls of dwarf transgenic mice: a cephalometric study.
Volume: 288
Issue: 3
Pages: 316-22
Publication
First Author: Imai J
Year: 2008
Journal: Science
Title: Regulation of pancreatic beta cell mass by neuronal signals from the liver.
Volume: 322
Issue: 5905
Pages: 1250-4
Publication
First Author: Wang S
Year: 2013
Journal: Biochim Biophys Acta
Title: ERK-mediated suppression of cilia in cisplatin-induced tubular cell apoptosis and acute kidney injury.
Volume: 1832
Issue: 10
Pages: 1582-90
GXD Expression      
Probe: MGI:3054040
Assay Type: Western blot
Annotation Date: 2004-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3054045
Age: embryonic day 11.5
Specimen Label: -/-
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3054040
Assay Type: Western blot
Annotation Date: 2004-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3054045
Age: embryonic day 11.5
Specimen Label: -/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3054040
Assay Type: Western blot
Annotation Date: 2004-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3054045
Age: embryonic day 11.5
Specimen Label: +/+
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3054040
Assay Type: Western blot
Annotation Date: 2004-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3054045
Age: embryonic day 11.5
Specimen Label: -/-
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3054040
Assay Type: Western blot
Annotation Date: 2004-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3054045
Age: embryonic day 11.5
Specimen Label: +/-
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3054040
Assay Type: Western blot
Annotation Date: 2004-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3054045
Age: embryonic day 11.5
Specimen Label: -/-
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3054040
Assay Type: Western blot
Annotation Date: 2004-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3054045
Age: embryonic day 11.5
Specimen Label: +/+
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3054040
Assay Type: Western blot
Annotation Date: 2004-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3054045
Age: embryonic day 11.5
Specimen Label: +/+
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3054040
Assay Type: Western blot
Annotation Date: 2004-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3054045
Age: embryonic day 11.5
Specimen Label: +/+
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:3054040
Assay Type: Western blot
Annotation Date: 2004-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3054045
Age: embryonic day 11.5
Specimen Label: +/+
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:3054040
Assay Type: Western blot
Annotation Date: 2004-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3054045
Age: embryonic day 11.5
Specimen Label: +/-
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:3054040
Assay Type: Western blot
Annotation Date: 2004-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3054045
Age: embryonic day 11.5
Specimen Label: +/-
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:3576758
Assay Type: RT-PCR
Annotation Date: 2005-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3577219
Age: embryonic day 1.5
Image: 1
Specimen Label: E1.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3576758
Assay Type: RT-PCR
Annotation Date: 2005-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3577219
Age: embryonic day 2.5
Image: 1
Specimen Label: E2.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3576758
Assay Type: RT-PCR
Annotation Date: 2005-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3577219
Age: embryonic day 3.5
Image: 1
Specimen Label: E3.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3830877
Assay Type: Northern blot
Annotation Date: 2009-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:3830976
Age: embryonic day 9.5
Specimen Label: 9.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3830877
Assay Type: Northern blot
Annotation Date: 2009-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:3830976
Age: embryonic day 10.5
Specimen Label: 10.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3830877
Assay Type: Northern blot
Annotation Date: 2009-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3830976
Age: embryonic day 11.5
Specimen Label: 11.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3830877
Assay Type: Northern blot
Annotation Date: 2009-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3830976
Age: embryonic day 12.5
Specimen Label: 12.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3830877
Assay Type: Northern blot
Annotation Date: 2009-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:3830976
Age: embryonic day 13.5
Specimen Label: 13.5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3830877
Assay Type: Northern blot
Annotation Date: 2009-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:3830976
Age: embryonic day 14.5
Specimen Label: 14.5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3830878
Assay Type: Northern blot
Annotation Date: 2009-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:3830979
Age: embryonic day 14.5
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3830878
Assay Type: Northern blot
Annotation Date: 2009-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:3830979
Age: embryonic day 14.5
Specimen Label: 4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3830878
Assay Type: Northern blot
Annotation Date: 2009-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3830979
Age: postnatal adult
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3830878
Assay Type: Northern blot
Annotation Date: 2009-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3830979
Age: postnatal adult
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3830969
Assay Type: Western blot
Annotation Date: 2009-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:3830984
Age: embryonic day 14.5
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3830969
Assay Type: Western blot
Annotation Date: 2009-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:3830984
Age: embryonic day 14.5
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3830969
Assay Type: Western blot
Annotation Date: 2009-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:3830984
Age: embryonic day 14.5
Specimen Label: 5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3830969
Assay Type: Western blot
Annotation Date: 2009-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3830984
Age: postnatal adult
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3830969
Assay Type: Western blot
Annotation Date: 2009-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3830984
Age: postnatal adult
Specimen Label: 4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3830969
Assay Type: Western blot
Annotation Date: 2009-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3830984
Age: postnatal adult
Specimen Label: 6
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3576758
Assay Type: RT-PCR
Annotation Date: 2005-05-18
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3577219
Age: postnatal adult
Image: 1
Specimen Label: Unf
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6195231
Assay Type: Western blot
Annotation Date: 2018-08-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752825
Stage: TS25
Assay Id: MGI:6195270
Age: embryonic day 17.5
Image: 7
Specimen Label: Het
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6195235
Assay Type: Western blot
Annotation Date: 2018-08-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752825
Stage: TS25
Assay Id: MGI:6195272
Age: embryonic day 17.5
Image: 7
Specimen Label: Het
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6195235
Assay Type: Western blot
Annotation Date: 2018-08-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752825
Stage: TS25
Assay Id: MGI:6195272
Age: embryonic day 17.5
Image: 7
Specimen Label: Null
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6195231
Assay Type: Western blot
Annotation Date: 2018-08-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752825
Stage: TS25
Assay Id: MGI:6195270
Age: embryonic day 17.5
Image: 7
Specimen Label: Null
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7506890
Assay Type: RT-PCR
Annotation Date: 2023-07-13
Strength: Present
Sex: Female
Emaps: EMAPS:3820522
Stage: TS22
Assay Id: MGI:7506921
Age: embryonic day 14.5
Specimen Label: Untr Male
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7506890
Assay Type: RT-PCR
Annotation Date: 2023-07-13
Strength: Present
Sex: Female
Emaps: EMAPS:3187822
Stage: TS22
Assay Id: MGI:7506921
Age: embryonic day 14.5
Specimen Label: Untr Male
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7506890
Assay Type: RT-PCR
Annotation Date: 2023-07-13
Strength: Present
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:7506921
Age: embryonic day 14.5
Specimen Label: Untr Male
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7506890
Assay Type: RT-PCR
Annotation Date: 2023-07-13
Strength: Present
Sex: Female
Emaps: EMAPS:3820522
Stage: TS22
Assay Id: MGI:7506921
Age: embryonic day 14.5
Specimen Label: Untr Female
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7506890
Assay Type: RT-PCR
Annotation Date: 2023-07-13
Strength: Present
Sex: Female
Emaps: EMAPS:3187822
Stage: TS22
Assay Id: MGI:7506921
Age: embryonic day 14.5
Specimen Label: Untr Female
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7506890
Assay Type: RT-PCR
Annotation Date: 2023-07-13
Strength: Present
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:7506921
Age: embryonic day 14.5
Specimen Label: Untr Female
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7506890
Assay Type: RT-PCR
Annotation Date: 2023-07-13
Strength: Present
Sex: Female
Emaps: EMAPS:3820525
Stage: TS25
Assay Id: MGI:7506923
Age: embryonic day 17.5
Specimen Label: Untr Male
Detected: true
Specimen Num: 1