|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 96 out of 96 for Map3k13

0.025s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Chen M
Year: 2018
Journal: Cell Rep
Title: Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS.
Volume: 22
Issue: 13
Pages: 3587-3597
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10537
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10558
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2853323
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10537
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10537
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10558
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1795023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10537
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1795023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10558
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4426804
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1857423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826080
Age: embryonic day 14.5
Image: euxassay_014094_10
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4426804
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1857423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826080
Age: embryonic day 14.5
Image: euxassay_014094_11
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4426804
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1857423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826080
Age: embryonic day 14.5
Image: euxassay_014094_12
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4426804
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1857423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826080
Age: embryonic day 14.5
Image: euxassay_014094_13
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1869223
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10537
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2854023
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10558
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10537
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10558
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10537
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10537
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10558
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:4426804
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826080
Age: embryonic day 14.5
Image: euxassay_014094_09
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4426804
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826080
Age: embryonic day 14.5
Image: euxassay_014094_10
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4426804
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826080
Age: embryonic day 14.5
Image: euxassay_014094_11
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4426804
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826080
Age: embryonic day 14.5
Image: euxassay_014094_13
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4426804
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826080
Age: embryonic day 14.5
Image: euxassay_014094_14
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4426804
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826080
Age: embryonic day 14.5
Image: euxassay_014094_15
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4426804
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826080
Age: embryonic day 14.5
Image: euxassay_014094_16
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4426804
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826080
Age: embryonic day 14.5
Image: euxassay_014094_17
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4426804
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826080
Age: embryonic day 14.5
Image: euxassay_014094_18
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10537
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10558
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10537
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10558
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10537
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10558
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10558
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:4426804
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826080
Age: embryonic day 14.5
Image: euxassay_014094_13
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4426804
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826080
Age: embryonic day 14.5
Image: euxassay_014094_14
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10537
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10558
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001864
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542418
Age: embryonic day 15.5
Image: GUDMAP:10558
Detected: false
Specimen Num: 2
Publication  
First Author: Chen M
Year: 2016
Journal: Sci Rep
Title: Leucine Zipper-bearing Kinase promotes axon growth in mammalian central nervous system neurons.
Volume: 6
Pages: 31482
Publication
First Author: Itoh A
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Impaired regenerative response of primary sensory neurons in ZPK/DLK gene-trap mice.
Volume: 383
Issue: 2
Pages: 258-62
Publication
First Author: Welsbie DS
Year: 2017
Journal: Neuron
Title: Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons.
Volume: 94
Issue: 6
Pages: 1142-1154.e6
Publication
First Author: Craig EA
Year: 2008
Journal: Dev Dyn
Title: MAP3Ks as central regulators of cell fate during development.
Volume: 237
Issue: 11
Pages: 3102-14
Publication
First Author: Saiga T
Year: 2009
Journal: Mol Cell Biol
Title: Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development.
Volume: 29
Issue: 13
Pages: 3529-43
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication
First Author: Ikeda A
Year: 2001
Journal: FEBS Lett
Title: Identification and characterization of functional domains in a mixed lineage kinase LZK.
Volume: 488
Issue: 3
Pages: 190-5
Publication
First Author: Ikeda A
Year: 2001
Journal: J Biochem
Title: Mixed lineage kinase LZK forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway.
Volume: 130
Issue: 6
Pages: 773-81
Protein Domain
Type: Family
Description: MAP3K13 (also known as leucine zipper-bearing kinase LZK) activates the c-Jun-NH2 terminal kinase (JNK) pathway through activation of the MAP kinase kinase MAP2K7 [, ]. MAP3K13 acts synergistically with peroxiredoxin-3 (PRDX3) to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B []. MAP3K13 forms dimers/oligomers through its dual leucine zipper-like motif, and that this is necessary for activation of the JNK/SAPK pathway [].
Publication
First Author: Masaki M
Year: 2003
Journal: Eur J Biochem
Title: Mixed lineage kinase LZK and antioxidant protein-1 activate NF-kappaB synergistically.
Volume: 270
Issue: 1
Pages: 76-83
Protein Domain
Type: Family
Description: This entry represents mitogen-activated protein kinase kinase kinase, types 12/13 (MAP3K12 and MAP3K13), which form part of the mixed lineage kinase (MLK) family. MAP3K12 (also known as leucine-zipper protein kinase (ZPK), dual leucine zipper-bearing kinase (DLK) or MAPK-upstream kinase (MUK)) is a MAPKKK class protein kinase that induces JNK/SAPK activation. MAP3K12 is known to interact with MUK-binding inhibitory protein (MBIP). MBIP contains two tandem leucine-zipper-like motifs; MBIP interacts with one of the two leucine-zipper-like motifs of MAP3K12 and inhibits the activity of MAP3K12 to induce JNK/SAPK activation [, ]. MAP3K12 is autophosphorylated on Ser/Thr in cytosol under basal conditions, and dephosphorylated when membrane-associated.MAP3K13 (also known as leucine zipper-bearing kinase LZK) activates the c-Jun-NH2 terminal kinase (JNK) pathway through activation of the MAP kinase kinase MAP2K7 []. MAP3K13 acts synergistically with peroxiredoxin-3 (PRDX3) to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B [].
Publication
First Author: Itoh A
Year: 2004
Journal: Biochem Biophys Res Commun
Title: SP3 acts as a positive regulator on the core promoter of human ZPK gene.
Volume: 313
Issue: 3
Pages: 612-8
Protein
Organism: Mus musculus
Length: 959  
Fragment?: false
Publication
First Author: Fukuyama K
Year: 2000
Journal: J Biol Chem
Title: MAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/dual leucine zipper-bearing kinase/leucine zipper protein kinase.
Volume: 275
Issue: 28
Pages: 21247-54
Protein
Organism: Mus musculus
Length: 888  
Fragment?: false