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Search results 1 to 100 out of 159 for Map4

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Microtubule-associated protein 4 (MAP4) is a non-neuronal microtubule-associated protein that promotes microtubule assembly [, ]. It contains a microtubule binding domain (Tau/MAP repeats) that shares homology with neuronal microtubule-associated protein MAP2 and Tau []. It is a ubiquitous heat-stable MAP responsible for stabilisation of microtubules []. Overexpression of MAP4 causes a shift of tubulin dimers to a polymerised fraction and formed dense, stable microtubule networks []. The persistent transcriptional up-regulation of MAP4, cardiac alpha- and beta-tubulinis is linked to the cytoskeletal abnormality during severe pressure overload-induced cardiac hypertrophy [].
Publication
First Author: Takahashi M
Year: 2003
Journal: Am J Physiol Heart Circ Physiol
Title: Phenotypic consequences of beta1-tubulin expression and MAP4 decoration of microtubules in adult cardiocytes.
Volume: 285
Issue: 5
Pages: H2072-83
Publication
First Author: Samora CP
Year: 2011
Journal: Nat Cell Biol
Title: MAP4 and CLASP1 operate as a safety mechanism to maintain a stable spindle position in mitosis.
Volume: 13
Issue: 9
Pages: 1040-50
Publication
First Author: Cheng G
Year: 2010
Journal: J Biol Chem
Title: Basis for MAP4 dephosphorylation-related microtubule network densification in pressure overload cardiac hypertrophy.
Volume: 285
Issue: 49
Pages: 38125-40
Publication
First Author: Cheng G
Year: 2005
Journal: Am J Physiol Heart Circ Physiol
Title: Inhibition of beta-adrenergic receptor trafficking in adult cardiocytes by MAP4 decoration of microtubules.
Volume: 288
Issue: 3
Pages: H1193-202
Publication
First Author: Ebneth A
Year: 1999
Journal: Cell Motil Cytoskeleton
Title: Phosphorylation of MAP2c and MAP4 by MARK kinases leads to the destabilization of microtubules in cells.
Volume: 44
Issue: 3
Pages: 209-24
Publication
First Author: Permana S
Year: 2005
Journal: Cell Struct Funct
Title: Truncation of the projection domain of MAP4 (microtubule-associated protein 4) leads to attenuation of microtubule dynamic instability.
Volume: 29
Issue: 5-6
Pages: 147-57
Publication
First Author: Kitazawa H
Year: 2000
Journal: Cell Struct Funct
Title: Ser787 in the proline-rich region of human MAP4 is a critical phosphorylation site that reduces its activity to promote tubulin polymerization.
Volume: 25
Issue: 1
Pages: 33-9
Protein
Organism: Mus musculus/domesticus
Length: 99  
Fragment?: false
Publication  
First Author: Chapin SJ
Year: 1991
Journal: J Cell Sci
Title: Non-neuronal 210 x 10(3) Mr microtubule-associated protein (MAP4) contains a domain homologous to the microtubule-binding domains of neuronal MAP2 and tau.
Volume: 98 ( Pt 1)
Pages: 27-36
Publication
First Author: Tokuraku K
Year: 2003
Journal: J Biol Chem
Title: The number of repeat sequences in microtubule-associated protein 4 affects the microtubule surface properties.
Volume: 278
Issue: 32
Pages: 29609-18
Publication
First Author: Chinnakkannu P
Year: 2010
Journal: J Biol Chem
Title: Site-specific microtubule-associated protein 4 dephosphorylation causes microtubule network densification in pressure overload cardiac hypertrophy.
Volume: 285
Issue: 28
Pages: 21837-48
Protein
Organism: Mus musculus/domesticus
Length: 1125  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 933  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 276  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1441  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 414  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 290  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 902  
Fragment?: false
Publication  
First Author: Li L
Year: 2018
Journal: EBioMedicine
Title: Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice.
Volume: 37
Pages: 221-235
Publication
First Author: Li L
Year: 2022
Journal: Cell Commun Signal
Title: Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy.
Volume: 20
Issue: 1
Pages: 115
Publication
First Author: Code RJ
Year: 1992
Journal: Gene
Title: Mouse microtubule-associated protein 4 (MAP4) transcript diversity generated by alternative polyadenylation.
Volume: 122
Issue: 2
Pages: 367-70
Publication  
First Author: Bizet AA
Year: 2015
Journal: Nat Commun
Title: Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization.
Volume: 6
Pages: 8666
Publication
First Author: Mangan ME
Year: 1996
Journal: Development
Title: A muscle-specific variant of microtubule-associated protein 4 (MAP4) is required in myogenesis.
Volume: 122
Issue: 3
Pages: 771-81
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: West RR
Year: 1991
Journal: J Biol Chem
Title: A model for microtubule-associated protein 4 structure. Domains defined by comparisons of human, mouse, and bovine sequences.
Volume: 266
Issue: 32
Pages: 21886-96
GXD Expression    
Probe: MGI:28298
Assay Type: Northern blot
Annotation Date: 1998-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1309347
Age: postnatal adult
Image: 5
Specimen Label: Skeletal muscle
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:28298
Assay Type: Northern blot
Annotation Date: 1998-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1309347
Age: postnatal adult
Image: 5
Specimen Label: Heart
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:28298
Assay Type: Northern blot
Annotation Date: 1998-11-16
Strength: Absent
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:1309347
Age: postnatal adult
Image: 5
Specimen Label: Uterus
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:28298
Assay Type: Northern blot
Annotation Date: 1998-11-16
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:1309347
Age: postnatal adult
Image: 5
Specimen Label: Testis
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:28298
Assay Type: Northern blot
Annotation Date: 1998-11-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1309347
Age: postnatal adult
Image: 5
Specimen Label: Brain
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:28298
Assay Type: Northern blot
Annotation Date: 1998-11-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1309347
Age: postnatal adult
Image: 5
Specimen Label: Lung
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:28298
Assay Type: Northern blot
Annotation Date: 1998-11-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1309347
Age: postnatal adult
Image: 5
Specimen Label: Kidney
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:2652435
Assay Type: Western blot
Annotation Date: 2003-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Stage: TS26
Assay Id: MGI:2652488
Age: embryonic day 19.0
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2652435
Assay Type: Western blot
Annotation Date: 2003-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Stage: TS26
Assay Id: MGI:2652488
Age: embryonic day 19.0
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2652435
Assay Type: Western blot
Annotation Date: 2003-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Stage: TS26
Assay Id: MGI:2652488
Age: embryonic day 19.0
Specimen Label: -/-
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2680593
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2680616
Age: postnatal adult
Image: 3
Specimen Label: +/+ te
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2680593
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2680616
Age: postnatal adult
Image: 3
Specimen Label: +/+ sp
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2680593
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:2680616
Age: postnatal adult
Image: 3
Specimen Label: +/+ mu
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2680593
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2680616
Age: postnatal adult
Image: 3
Specimen Label: +/+ lu
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2680593
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2680616
Age: postnatal adult
Image: 3
Specimen Label: +/+ li
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:2680593
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2680616
Age: postnatal adult
Image: 3
Specimen Label: +/+ ki
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:2680593
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2680616
Age: postnatal adult
Image: 3
Specimen Label: +/+ he
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:2680593
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624728
Stage: TS28
Assay Id: MGI:2680616
Age: postnatal adult
Image: 3
Specimen Label: +/+ gu
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:2680593
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:2680616
Age: embryonic day 12.5
Image: 3
Specimen Label: +/+ 12
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:2680593
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2680616
Age: postnatal adult
Image: 3
Specimen Label: +/+ br
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:2680593
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2680617
Age: postnatal adult
Image: 3
Specimen Label: brain +/+
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2680593
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2680617
Age: postnatal adult
Image: 3
Specimen Label: kidney +/+
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2680599
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2680618
Age: postnatal adult
Image: 4
Specimen Label: kidney +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2680599
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2680618
Age: postnatal adult
Image: 4
Specimen Label: brain +/+
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2680601
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2680619
Age: postnatal adult
Image: 4
Specimen Label: kidney +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2680601
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2680619
Age: postnatal adult
Image: 4
Specimen Label: brain +/+
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2680603
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2680620
Age: postnatal adult
Image: 4
Specimen Label: kidney +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2680603
Assay Type: Northern blot
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2680620
Age: postnatal adult
Image: 4
Specimen Label: brain +/+
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3606436
Assay Type: Western blot
Annotation Date: 2005-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3263428
Stage: TS28
Assay Id: MGI:3607167
Age: postnatal adult
Image: 6
Specimen Label: adult
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:3759492
Assay Type: Northern blot
Annotation Date: 2007-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914428
Stage: TS28
Assay Id: MGI:3759494
Age: postnatal adult
Image: 6
Specimen Label: adult
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:2252984
Assay Type: RNA in situ
Annotation Date: 2023-09-26
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7530867
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:16424
Assay Type: RNA in situ
Annotation Date: 1998-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1770121
Pattern: Uniform
Stage: TS21
Assay Id: MGI:1309399
Age: embryonic day 13.0
Image: 7C.
Specimen Label: 7C.
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:28298
Assay Type: RNA in situ
Annotation Date: 1998-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1770121
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:1309400
Age: embryonic day 13.0
Image: 7D.
Specimen Label: 7D.
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:28298
Assay Type: RNA in situ
Annotation Date: 1998-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598821
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:1309400
Age: embryonic day 13.0
Image: 7B.
Specimen Label: 7B.
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:28298
Assay Type: RNA in situ
Annotation Date: 1998-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598821
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:1309400
Age: embryonic day 13.0
Image: 7D.
Specimen Label: 7D.
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:28298
Assay Type: RNA in situ
Annotation Date: 1998-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:1309400
Age: embryonic day 14.0
Specimen Label: Not Shown
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:28298
Assay Type: RNA in situ
Annotation Date: 1998-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:1309400
Age: embryonic day 15.0
Specimen Label: Not Shown
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:28298
Assay Type: RNA in situ
Annotation Date: 1998-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:1309400
Age: embryonic day 16.0
Specimen Label: Not Shown
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:16424
Assay Type: RNA in situ
Annotation Date: 1998-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1774321
Pattern: Uniform
Stage: TS21
Assay Id: MGI:1309399
Age: embryonic day 13.0
Image: 7C.
Specimen Label: 7C.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:16424
Assay Type: RNA in situ
Annotation Date: 1998-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:1309399
Age: embryonic day 13.0
Image: 7A.
Note: Expression is at relatively uniform levels in most tissues.
Specimen Label: 7A.
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:16424
Assay Type: RNA in situ
Annotation Date: 1998-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:1309399
Age: embryonic day 13.0
Image: 7C.
Note: Expression is at relatively uniform levels in most tissues.
Specimen Label: 7C.
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:16424
Assay Type: RNA in situ
Annotation Date: 1998-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1718521
Pattern: Uniform
Stage: TS21
Assay Id: MGI:1309399
Age: embryonic day 13.0
Image: 7E.
Specimen Label: 7E.
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:28298
Assay Type: RNA in situ
Annotation Date: 1998-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1718521
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:1309400
Age: embryonic day 13.0
Image: 7E.
Specimen Label: 7E.
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:28298
Assay Type: RNA in situ
Annotation Date: 1998-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1617718
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:1309400
Age: embryonic day 11.0
Note: Expression is in the pre-thoracic muscles.
Specimen Label: Not Shown
Detected: true
Specimen Num: 1