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Search results 1 to 100 out of 389 for Mapkapk2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Tripathi D
Year: 2019
Journal: Arterioscler Thromb Vasc Biol
Title: Proinflammatory Effect of Endothelial Microparticles Is Mitochondria Mediated and Modulated Through MAPKAPK2 (MAPK-Activated Protein Kinase 2) Leading to Attenuation of Cardiac Hypertrophy.
Volume: 39
Issue: 6
Pages: 1100-1112
Publication
First Author: Wu Y
Year: 2007
Journal: Biochem Biophys Res Commun
Title: MAPKAPK2-mediated LSP1 phosphorylation and FMLP-induced neutrophil polarization.
Volume: 358
Issue: 1
Pages: 170-5
Publication
First Author: Herranz N
Year: 2015
Journal: Nat Cell Biol
Title: mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.
Volume: 17
Issue: 9
Pages: 1205-17
Publication
First Author: Henriques A
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Mesenchymal MAPKAPK2/HSP27 drives intestinal carcinogenesis.
Volume: 115
Issue: 24
Pages: E5546-E5555
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Kotlyarov A
Year: 1999
Journal: Nat Cell Biol
Title: MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis.
Volume: 1
Issue: 2
Pages: 94-7
Publication
First Author: Engel K
Year: 1998
Journal: EMBO J
Title: Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation.
Volume: 17
Issue: 12
Pages: 3363-71
Publication
First Author: Culbert AA
Year: 2006
Journal: J Biol Chem
Title: MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease.
Volume: 281
Issue: 33
Pages: 23658-67
Publication
First Author: Privitera L
Year: 2022
Journal: Aging Cell
Title: The MK2 cascade mediates transient alteration in mGluR-LTD and spatial learning in a murine model of Alzheimer's disease.
Volume: 21
Issue: 10
Pages: e13717
Publication
First Author: Liu T
Year: 2007
Journal: Am J Respir Cell Mol Biol
Title: Lack of MK2 inhibits myofibroblast formation and exacerbates pulmonary fibrosis.
Volume: 37
Issue: 5
Pages: 507-17
Publication
First Author: Lehner MD
Year: 2002
Journal: J Immunol
Title: Mitogen-activated protein kinase-activated protein kinase 2-deficient mice show increased susceptibility to Listeria monocytogenes infection.
Volume: 168
Issue: 9
Pages: 4667-73
Publication
First Author: Ghasemlou N
Year: 2010
Journal: J Neurosci
Title: Mitogen-activated protein kinase-activated protein kinase 2 (MK2) contributes to secondary damage after spinal cord injury.
Volume: 30
Issue: 41
Pages: 13750-9
Publication
First Author: Ray AL
Year: 2016
Journal: Int J Cancer
Title: Blockade of MK2 is protective in inflammation-associated colorectal cancer development.
Volume: 138
Issue: 3
Pages: 770-5
Publication
First Author: Limbourg A
Year: 2015
Journal: PLoS One
Title: MAP-Kinase Activated Protein Kinase 2 Links Endothelial Activation and Monocyte/macrophage Recruitment in Arteriogenesis.
Volume: 10
Issue: 10
Pages: e0138542
Publication
First Author: Bouska A
Year: 2009
Journal: Cancer Res
Title: Mdm2 affects genome stability independent of p53.
Volume: 69
Issue: 5
Pages: 1697-701
Publication
First Author: Hannigan MO
Year: 2001
Journal: J Immunol
Title: Abnormal migration phenotype of mitogen-activated protein kinase-activated protein kinase 2-/- neutrophils in Zigmond chambers containing formyl-methionyl-leucyl-phenylalanine gradients.
Volume: 167
Issue: 7
Pages: 3953-61
Publication
First Author: Thomas T
Year: 2008
Journal: Eur J Neurosci
Title: MAP-kinase-activated protein kinase 2 expression and activity is induced after neuronal depolarization.
Volume: 28
Issue: 4
Pages: 642-54
Publication
First Author: Mao X
Year: 2014
Journal: J Invest Dermatol
Title: MAPKAP kinase 2 (MK2)-dependent and -independent models of blister formation in pemphigus vulgaris.
Volume: 134
Issue: 1
Pages: 68-76
Publication  
First Author: Herbert BA
Year: 2017
Journal: Infect Immun
Title: Mitogen-Activated Protein Kinase 2 Signaling Shapes Macrophage Plasticity in Aggregatibacter actinomycetemcomitans-Induced Bone Loss.
Volume: 85
Issue: 1
Publication
First Author: Shiroto K
Year: 2005
Journal: J Mol Cell Cardiol
Title: MK2-/- gene knockout mouse hearts carry anti-apoptotic signal and are resistant to ischemia reperfusion injury.
Volume: 38
Issue: 1
Pages: 93-7
Publication
First Author: Ruiz M
Year: 2016
Journal: Diabetes
Title: MK2 Deletion in Mice Prevents Diabetes-Induced Perturbations in Lipid Metabolism and Cardiac Dysfunction.
Volume: 65
Issue: 2
Pages: 381-92
Publication
First Author: Funding AT
Year: 2009
Journal: J Invest Dermatol
Title: Reduced oxazolone-induced skin inflammation in MAPKAP kinase 2 knockout mice.
Volume: 129
Issue: 4
Pages: 891-8
Publication
First Author: Thuraisingam T
Year: 2010
Journal: J Invest Dermatol
Title: MAPKAPK-2 signaling is critical for cutaneous wound healing.
Volume: 130
Issue: 1
Pages: 278-86
Publication
First Author: de Boer JF
Year: 2014
Journal: PLoS One
Title: Mitogen-activated protein kinase-activated protein kinase 2 deficiency reduces insulin sensitivity in high-fat diet-fed mice.
Volume: 9
Issue: 9
Pages: e106300
Publication
First Author: Nagy N
Year: 2007
Journal: J Mol Cell Cardiol
Title: Ischemic preconditioning involves dual cardio-protective axes with p38MAPK as upstream target.
Volume: 42
Issue: 5
Pages: 981-90
Publication
First Author: Hegen M
Year: 2006
Journal: J Immunol
Title: MAPKAP kinase 2-deficient mice are resistant to collagen-induced arthritis.
Volume: 177
Issue: 3
Pages: 1913-7
Publication
First Author: Herbert BA
Year: 2015
Journal: PLoS One
Title: Sexual Dimorphism in MAPK-Activated Protein Kinase-2 (MK2) Regulation of RANKL-Induced Osteoclastogenesis in Osteoclast Progenitor Subpopulations.
Volume: 10
Issue: 5
Pages: e0125387
Publication
First Author: Soukup K
Year: 2017
Journal: Sci Rep
Title: Loss of MAPK-activated protein kinase 2 enables potent dendritic cell-driven anti-tumour T cell response.
Volume: 7
Issue: 1
Pages: 11746
Publication
First Author: Yuan J
Year: 2010
Journal: PLoS One
Title: MAPK-activated protein kinase 2 is required for mouse meiotic spindle assembly and kinetochore-microtubule attachment.
Volume: 5
Issue: 6
Pages: e11247
Publication
First Author: Noguchi N
Year: 2013
Journal: Arch Biochem Biophys
Title: Phosphorylation of epidermal growth factor receptor at serine 1047 by MAP kinase-activated protein kinase-2 in cultured lung epithelial cells treated with flagellin.
Volume: 529
Issue: 2
Pages: 75-85
Publication
First Author: Ray AL
Year: 2018
Journal: Int J Cancer
Title: Inhibition of MK2 suppresses IL-1β, IL-6, and TNF-α-dependent colorectal cancer growth.
Volume: 142
Issue: 8
Pages: 1702-1711
Publication  
First Author: Fan W
Year: 2018
Journal: Mol Cell Biol
Title: Hsp70 Interacts with Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinase 2 To Regulate p38MAPK Stability and Myoblast Differentiation during Skeletal Muscle Regeneration.
Volume: 38
Issue: 24
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: brain - total
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: cortex
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755028
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: brain medulla
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: cerebellum
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: brainstem
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: olfactory bulb
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: spinal cord
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: eye
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915328
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: harderian gland
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: heart
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: lung
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: liver
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: pancreas
Detected: false
Specimen Num: 13
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: kidney
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: spleen
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: thymus
Detected: true
Specimen Num: 16
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3552328
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: lymph nodes
Detected: true
Specimen Num: 17
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: bone marrow
Detected: false
Specimen Num: 18
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: skin
Detected: true
Specimen Num: 19
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1720228
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: gallbladder
Detected: true
Specimen Num: 20
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: urinary bladder
Detected: true
Specimen Num: 21
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: pituitary gland
Detected: true
Specimen Num: 22
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: adrenal gland
Detected: true
Specimen Num: 23
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1775128
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: salivary gland
Detected: true
Specimen Num: 24
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: skeletal muscle
Detected: true
Specimen Num: 25
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1718528
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: tongue
Detected: true
Specimen Num: 26
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: stomach
Detected: true
Specimen Num: 27
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: small intestine
Detected: true
Specimen Num: 28
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1925228
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: large intestine
Detected: true
Specimen Num: 29
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3519728
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: cecum
Detected: true
Specimen Num: 30
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: testis
Detected: true
Specimen Num: 31
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: epididymis
Detected: true
Specimen Num: 32
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Male
Emaps: EMAPS:1918028
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: seminal vesicle
Detected: true
Specimen Num: 33
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Male
Emaps: EMAPS:2979428
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: coagulating gland
Detected: true
Specimen Num: 34
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: prostate gland
Detected: true
Specimen Num: 35
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: ovary
Detected: true
Specimen Num: 36
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Absent
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: uterus
Detected: false
Specimen Num: 37
GXD Expression      
Probe: MGI:3625349
Assay Type: RT-PCR
Annotation Date: 2006-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3592628
Stage: TS28
Assay Id: MGI:3625350
Age: postnatal
Specimen Label: white fat
Detected: true
Specimen Num: 38
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2006-07-27
Strength: Very strong
Sex: Male
Emaps: EMAPS:3579528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3639259
Age: postnatal day 56
Image: Mouse 451449 - Image 99257593
Note: There is scattered expression in the white matter.
Specimen Label: Mouse 451449 - Image 99257593
Detected: true
Specimen Num: 92
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2006-07-27
Strength: Strong
Sex: Male
Emaps: EMAPS:1716128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3639259
Age: postnatal day 56
Image: Mouse 451449 - Image 99257412
Note: There is scattered expression in the cornea.
Specimen Label: Mouse 451449 - Image 99257412
Detected: true
Specimen Num: 40
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2006-07-27
Strength: Very strong
Sex: Male
Emaps: EMAPS:1876728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3639259
Age: postnatal day 56
Image: Mouse 451449 - Image 99257583
Note: Expression is present in practically all cells of the blood vessels of the spleen.
Specimen Label: Mouse 451449 - Image 99257583
Detected: true
Specimen Num: 82