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Search results 1 to 92 out of 92 for Mapre3

0.039s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
22924 | MAPRE3
Type: gene
Organism: human
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Gene
106992881 | MAPRE3
Type: gene
Organism: macaque, rhesus
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Gene
116410812 | mapre3
Type: gene
Organism: frog, western clawed
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Gene
298848 | Mapre3
Type: gene
Organism: rat
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Gene
741019 | MAPRE3
Type: gene
Organism: chimpanzee
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Gene
475694 | MAPRE3
Type: gene
Organism: dog, domestic
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Gene
528839 | MAPRE3
Type: gene
Organism: cattle
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Gene
100857732 | MAPRE3
Type: gene
Organism: chicken
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Protein Coding Gene
MGI:2140967 | Mapre3
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
100129724 | MAPRE3-AS1
Type: gene
Organism: human
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Publication
17658256 | J:127422
First Author: Straube A
Year: 2007
Journal: Curr Biol
Title: EB3 regulates microtubule dynamics at the cell cortex and is required for myoblast elongation and fusion.
Volume: 17
Issue: 15
Pages: 1318-25
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Protein Coding Gene
MGP_CAROLIEiJ_G0027064 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029396 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029362 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029313 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029373 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029094 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2140967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029826 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028505 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029062 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029211 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029169 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029296 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029198 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0029860 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028229 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0028585 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029317 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028082 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
26119739 | J:224855
First Author: Geyer M
Year: 2015
Journal: Cell Rep
Title: Microtubule-Associated Protein EB3 Regulates IP3 Receptor Clustering and Ca(2+) Signaling in Endothelial Cells.
Volume: 12
Issue: 1
Pages: 79-89
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Publication
29247211 | J:323751
First Author: Pchitskaya E
Year: 2017
Journal: Sci Rep
Title: Stim2-Eb3 Association and Morphology of Dendritic Spines in Hippocampal Neurons.
Volume: 7
Issue: 1
Pages: 17625
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Publication
18230754 | J:134358
First Author: Patel-Hett S
Year: 2008
Journal: Blood
Title: Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules.
Volume: 111
Issue: 9
Pages: 4605-16
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Publication
25761518 | J:222292
First Author: Sayas CL
Year: 2015
Journal: J Neurochem
Title: Tau regulates the localization and function of End-binding proteins 1 and 3 in developing neuronal cells.
Volume: 133
Issue: 5
Pages: 653-67
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Publication
24145165 | J:207946
First Author: Oddoux S
Year: 2013
Journal: J Cell Biol
Title: Microtubules that form the stationary lattice of muscle fibers are dynamic and nucleated at Golgi elements.
Volume: 203
Issue: 2
Pages: 205-13
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Publication
21079248 | J:166828
First Author: Thon JN
Year: 2010
Journal: J Cell Biol
Title: Cytoskeletal mechanics of proplatelet maturation and platelet release.
Volume: 191
Issue: 4
Pages: 861-74
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Publication
23572079 | J:198528
First Author: Tortosa E
Year: 2013
Journal: EMBO J
Title: MAP1B regulates microtubule dynamics by sequestering EB1/3 in the cytosol of developing neuronal cells.
Volume: 32
Issue: 9
Pages: 1293-306
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Publication
32163033 | J:290279
   
First Author: Crapster JA
Year: 2020
Journal: Elife
Title: HIPK4 is essential for murine spermiogenesis.
Volume: 9
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Publication
16148041 | J:107111
First Author: Komarova Y
Year: 2005
Journal: Mol Biol Cell
Title: EB1 and EB3 control CLIP dissociation from the ends of growing microtubules.
Volume: 16
Issue: 11
Pages: 5334-45
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Publication
17310996 | J:131462
First Author: Hsieh PC
Year: 2007
Journal: Oncogene
Title: p53 downstream target DDA3 is a novel microtubule-associated protein that interacts with end-binding protein EB3 and activates beta-catenin pathway.
Volume: 26
Issue: 34
Pages: 4928-40
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Publication
34983065 | J:338075
First Author: Wen Q
Year: 2022
Journal: Brain
Title: Inactivating Celsr2 promotes motor axon fasciculation and regeneration in mouse and human.
Volume: 145
Issue: 2
Pages: 670-683
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Publication
25024228 | J:212241
First Author: Boutin C
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: A dual role for planar cell polarity genes in ciliated cells.
Volume: 111
Issue: 30
Pages: E3129-38
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Publication
36343267 | J:333796
First Author: Ruiz-Reig N
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: KIF2A deficiency causes early-onset neurodegeneration.
Volume: 119
Issue: 46
Pages: e2209714119
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Publication
- | J:165965
     
First Author: Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource
Year: 2010
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Europhenome
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Domain
IPR027735 | RP1/EB2_vertebrate
Type: Family
Description: Microtubule-associated protein RP/EB family member 2 (also known as RP1 or EB2) belongs to the RP/EB family, which consists of MAPRE1 (EB1), MAPRE2 (RP1, also known as EB2) and MAPRE3 (EBF3, also known as EB3). Unlike EB1 and EB3, EB2 does not promote persistent microtubule growth by suppressing catastrophes []. It has been shown that MAPRE2 is highly expressed in pancreatic cancer cells, and seems to be involved in perineural invasion [].
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Protein Domain
IPR027738 | EB3
Type: Family
Description: Microtubule-assocaiated protein RP/EB family member 3 (EB3) belongs to the RP/EB family, which consists of MAPRE1 (EB1), MAPRE2 (RP1, also known as EB2) and MAPRE3 (EBF3, also known as EB3). EB3 promotes persistent microtubule growth by suppressing catastrophes []. Unlike EB1 or EB2, EB3 also binds to the F-actin-binding protein drebrin and the E3 ubiquitin ligase SIAH-1 []. EB3 is specifically upregulated upon myogenic differentiation. Knockdown of EB3, but not that of EB1, prevents myoblast elongation and fusion into myotubes [].
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Publication
19255245 | -
First Author: Komarova Y
Year: 2009
Journal: J Cell Biol
Title: Mammalian end binding proteins control persistent microtubule growth.
Volume: 184
Issue: 5
Pages: 691-706
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Publication
19632184 | -
First Author: Honnappa S
Year: 2009
Journal: Cell
Title: An EB1-binding motif acts as a microtubule tip localization signal.
Volume: 138
Issue: 2
Pages: 366-76
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Protein Domain
IPR027739 | EB1_Meta
Type: Family
Description: Microtubule-associated protein RP/EB family member 1 (EB1) belongs to the RP/EB family, which consists of MAPRE1 (EB1), MAPRE2 (RP1, also known as EB2) and MAPRE3 (EBF3, also known as EB3). EB1 binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. EB1 contains an N-terminal calponin homology (CH) domain that is responsible for the interaction with microtubules (MTs), and a C-terminal coiled coil domain that extends into a four-helix bundle, required for dimer formation []. Through their C-terminal sequences, EBs interact with most other known +TIPs (plus end tracking proteins) and recruit many of them to the growing MT ends [, ]. EB1 is involved in MT anchoring at the centrosome and cell migration [].
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Publication
15311282 | -
First Author: Wen Y
Year: 2004
Journal: Nat Cell Biol
Title: EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration.
Volume: 6
Issue: 9
Pages: 820-30
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Publication
12388762 | -
First Author: Askham JM
Year: 2002
Journal: Mol Biol Cell
Title: Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome.
Volume: 13
Issue: 10
Pages: 3627-45
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Publication
19787265 | -
First Author: Abiatari I
Year: 2009
Journal: Int J Oncol
Title: The microtubule-associated protein MAPRE2 is involved in perineural invasion of pancreatic cancer cells.
Volume: 35
Issue: 5
Pages: 1111-6
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Publication
18322465 | -
First Author: Akhmanova A
Year: 2008
Journal: Nat Rev Mol Cell Biol
Title: Tracking the ends: a dynamic protein network controls the fate of microtubule tips.
Volume: 9
Issue: 4
Pages: 309-22
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Publication
20008324 | -
First Author: De Groot CO
Year: 2010
Journal: J Biol Chem
Title: Molecular insights into mammalian end-binding protein heterodimerization.
Volume: 285
Issue: 8
Pages: 5802-14
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Publication
21062375 | -
First Author: Liu H
Year: 2010
Journal: Mol Microbiol
Title: Aspergillus fumigatus AcuM regulates both iron acquisition and gluconeogenesis.
Volume: 78
Issue: 4
Pages: 1038-54
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Publication
18806788 | -
First Author: Geraldo S
Year: 2008
Journal: Nat Cell Biol
Title: Targeting of the F-actin-binding protein drebrin by the microtubule plus-tip protein EB3 is required for neuritogenesis.
Volume: 10
Issue: 10
Pages: 1181-9
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Protein Domain
IPR027328 | MAPRE
Type: Family
Description: This entry represents the microtubule-associated protein RP/EB (MAPRE) family, including MAPRE1 (EB1), MAPRE2 (RP1, also known as EB2), MAPRE3 (EBF3, also known as EB3) and their homologues from eukaryotes. Despite their high protein sequence conservation, the individual EBs exhibit different regulatory and functional properties []. For instance, EB1 and EB3, but not EB2, promote persistent microtubule growth by suppressing catastrophes [].EB1 contains an N-terminal calponin homology (CH) domain that is responsible for the interaction with microtubules (MTs), and a C-terminal coiled coil domain that extends into a four-helix bundle, required for dimer formation []. Through their C-terminal sequences, EBs interact with most other known +TIPs (plus end tracking proteins) and recruit many of them to the growing MT ends [, ]. EB1 is involved in MT anchoring at the centrosome and cell migration []. EB2 is highly expressed in pancreatic cancer cells, and seems to be involved in perineural invasion []. EB3 is specifically upregulated upon myogenic differentiation. Knockdown of EB3, but not that of EB1, prevents myoblast elongation and fusion into myotubes []. This entry also includes bZIP transcription factor hapX from the yeast Neosartorya fumigata, which is a transcription factor required for repression of genes during iron starvation [].
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Protein
A0A0J9YVB9
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: true
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Protein
Q3TG90
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: false
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Protein
Q61166
Organism: Mus musculus/domesticus
Length: 268  
Fragment?: false
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Protein
Q8R001
Organism: Mus musculus/domesticus
Length: 326  
Fragment?: false
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Protein
Q6PER3
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: false
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Protein
E9Q6X0
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
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Protein
Q3U4H0
Organism: Mus musculus/domesticus
Length: 268  
Fragment?: false
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Protein
D3YYK8
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: true
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Protein
Q2UZW7
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: false
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Protein
D3Z6G3
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom