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Search results 1 to 100 out of 2279 for Mapt

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Type Details Score
Gene
4137 | MAPT
Type: gene
Organism: human
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Gene
450177 | MAPT
Type: gene
Organism: chimpanzee
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Gene
480488 | MAPT
Type: gene
Organism: dog, domestic
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Gene
426737 | MAPT
Type: gene
Organism: chicken
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Gene
574327 | MAPT
Type: gene
Organism: macaque, rhesus
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Gene
779920 | mapt
Type: gene
Organism: frog, western clawed
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Gene
281296 | MAPT
Type: gene
Organism: cattle
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Gene
key_37175 | MAPT
Type: gene
Organism: goat
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Gene
29477 | Mapt
Type: gene
Organism: rat
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Protein Coding Gene
MGI:97180 | Mapt
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
100128977 | MAPT-AS1
Type: gene
Organism: human
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Gene
100130148 | MAPT-IT1
Type: gene
Organism: human
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Publication
37047532 | J:334899
 
First Author: Andrés-Benito P
Year: 2023
Journal: Int J Mol Sci
Title: Deregulated Transcription and Proteostasis in Adult mapt Knockout Mouse.
Volume: 24
Issue: 7
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Publication
30290707 | J:310931
First Author: Xu Y
Year: 2019
Journal: Autophagy
Title: The cargo receptor SQSTM1 ameliorates neurofibrillary tangle pathology and spreading through selective targeting of pathological MAPT (microtubule associated protein tau).
Volume: 15
Issue: 4
Pages: 583-598
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6393446
Age: postnatal day 0
Image: 7 Mapt P0
Note: Expression was detected in hair cells; a subset co-localized with Mapt.
Specimen Label: 7 Mapt P0
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6393446
Age: postnatal day 0
Image: 7 Mapt P0 orthogonal
Note: Expression was detected in hair cells; a subset co-localized with Mapt.
Specimen Label: 7 Mapt P0 orthogonal
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393446
Age: postnatal day 12
Image: 7 Mapt P12
Note: Expression was detected in hair cells; a subset co-localized with Mapt.
Specimen Label: 7 Mapt P12
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393446
Age: postnatal day 12
Image: 7 Mapt P12 orthogonal
Note: Expression was detected in hair cells; a subset co-localized with Mapt.
Specimen Label: 7 Mapt P12 orthogonal
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393446
Age: postnatal day 64
Image: 7 Mapt P64
Note: Expression was detected in hair cells; a subset co-localized with Mapt.
Specimen Label: 7 Mapt P64
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393446
Age: postnatal day 64
Image: 7 Mapt P64 orthogonal
Note: Expression was detected in hair cells; a subset co-localized with Mapt.
Specimen Label: 7 Mapt P64 orthogonal
Detected: true
Specimen Num: 24
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Publication
29282277 | J:329754
First Author: Caneus J
Year: 2018
Journal: Mol Biol Cell
Title: Mitotic defects lead to neuronal aneuploidy and apoptosis in frontotemporal lobar degeneration caused by MAPT mutations.
Volume: 29
Issue: 5
Pages: 575-586
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Publication
36635241 | J:332555
 
First Author: Huang M
Year: 2022
Journal: eNeuro
Title: Increase in Tau Pathology in P290S Mapt Knock-In Mice Crossed with App (NL-G-F) Mice.
Volume: 9
Issue: 6
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Publication
29729423 | J:264741
 
First Author: Adalbert R
Year: 2018
Journal: Neurobiol Aging
Title: Interaction between a MAPT variant causing frontotemporal dementia and mutant APP affects axonal transport.
Volume: 68
Pages: 68-75
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GXD Expression
GXD Expression
   
Probe: MGI:6177589
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190766
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Mapt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6177589
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190766
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Mapt
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6177589
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190766
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Mapt
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6177589
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190766
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Mapt
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6177589
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190766
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Mapt
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6177589
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190766
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Mapt
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6177589
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190766
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Mapt
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:6393274
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-05
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1729327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6393311
Age: postnatal day 0
Image: 7 P0 orthogonal
Note: At P0, Mapt was barely detected in the utricle.
Specimen Label: 7 P0 orthogonal
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6393274
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-05
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1729327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6393311
Age: postnatal day 0
Image: 7 P0
Note: At P0, Mapt was barely detected in the utricle.
Specimen Label: 7 P0
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6393274
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393311
Age: postnatal day 64
Image: 4D
Note: There was broad overlap of Mapt expression with the Type II hair cell marker, Calb2.
Specimen Label: 4D
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6393274
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393311
Age: postnatal day 12
Image: 7 P12
Note: At P12, Mapt was expressed in a significant number of Type II hair cells.
Specimen Label: 7 P12
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:6393274
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393311
Age: postnatal day 12
Image: 7 P12 orthogonal
Note: At P12, Mapt was expressed in a significant number of Type II hair cells.
Specimen Label: 7 P12 orthogonal
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:6393274
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393311
Age: postnatal day 64
Image: 7 P64
Note: At P64, Mapt was expressed in a significant number of Type II hair cells.
Specimen Label: 7 P64
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:6393274
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393311
Age: postnatal day 64
Image: 7 P64 orthogonal
Note: At P64, Mapt was expressed in a significant number of Type II hair cells.
Specimen Label: 7 P64 orthogonal
Detected: true
Specimen Num: 9
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Publication
31273083 | J:280392
First Author: Saito T
Year: 2019
Journal: J Biol Chem
Title: Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation.
Volume: 294
Issue: 34
Pages: 12754-12765
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Publication
30128323 | J:264801
First Author: Chen C
Year: 2018
Journal: Ann Clin Transl Neurol
Title: Mapt deletion fails to rescue premature lethality in two models of sodium channel epilepsy.
Volume: 5
Issue: 8
Pages: 982-987
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Publication
25863528 | J:222621
First Author: Komuro Y
Year: 2015
Journal: Neurobiol Aging
Title: Human tau expression reduces adult neurogenesis in a mouse model of tauopathy.
Volume: 36
Issue: 6
Pages: 2034-42
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Publication
23459933 | J:198237
First Author: Avale ME
Year: 2013
Journal: Hum Mol Genet
Title: Trans-splicing correction of tau isoform imbalance in a mouse model of tau mis-splicing.
Volume: 22
Issue: 13
Pages: 2603-11
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Publication
35054902 | J:318850
 
First Author: Andrés-Benito P
Year: 2022
Journal: Int J Mol Sci
Title: Host Tau Genotype Specifically Designs and Regulates Tau Seeding and Spreading and Host Tau Transformation Following Intrahippocampal Injection of Identical Tau AD Inoculum.
Volume: 23
Issue: 2
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Publication
28859549 | J:285080
First Author: Kokiko-Cochran ON
Year: 2018
Journal: J Neurotrauma
Title: Traumatic Brain Injury in hTau Model Mice: Enhanced Acute Macrophage Response and Altered Long-Term Recovery.
Volume: 35
Issue: 1
Pages: 73-84
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Publication
36389767 | J:332109
 
First Author: Katsumoto A
Year: 2022
Journal: Front Immunol
Title: Triggering receptor expressed on myeloid cells 2 deficiency exacerbates injury-induced inflammation in a mouse model of tauopathy.
Volume: 13
Pages: 978423
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Publication
28367114 | J:284907
 
First Author: Maphis NM
Year: 2017
Journal: Front Mol Neurosci
Title: Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology.
Volume: 10
Pages: 69
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Publication
31065832 | J:294428
First Author: Sartori M
Year: 2019
Journal: Acta Neuropathol
Title: BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation.
Volume: 138
Issue: 4
Pages: 631-652
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Publication
26311071 | J:229560
 
First Author: Xu L
Year: 2015
Journal: Exp Neurol
Title: Evidence for accelerated tauopathy in the retina of transgenic P301S tau mice exposed to repetitive mild traumatic brain injury.
Volume: 273
Pages: 168-76
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Publication
31223056 | J:306853
First Author: Feng Q
Year: 2020
Journal: Autophagy
Title: MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration.
Volume: 16
Issue: 4
Pages: 641-658
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Publication
31765727 | J:310719
 
First Author: Cheng H
Year: 2020
Journal: Neurobiol Dis
Title: Tau overexpression exacerbates neuropathology after repeated mild head impacts in male mice.
Volume: 134
Pages: 104683
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Publication
30120733 | J:285073
First Author: Comerota MM
Year: 2019
Journal: Mol Neurobiol
Title: Near Infrared Light Treatment Reduces Synaptic Levels of Toxic Tau Oligomers in Two Transgenic Mouse Models of Human Tauopathies.
Volume: 56
Issue: 5
Pages: 3341-3355
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Publication
19041304 | J:174270
First Author: Levine S
Year: 2009
Journal: Exp Mol Pathol
Title: Systemic pathology in aged mouse models of Down's syndrome and Alzheimer's disease.
Volume: 86
Issue: 1
Pages: 18-22
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Publication
33482356 | J:307763
 
First Author: Marquez A
Year: 2021
Journal: Neurobiol Dis
Title: Tau associated peripheral and central neurodegeneration: Identification of an early imaging marker for tauopathy.
Volume: 151
Pages: 105273
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Publication
29660685 | J:264770
 
First Author: Dengler-Crish CM
Year: 2018
Journal: Neurobiol Aging
Title: Evidence of Wnt/β-catenin alterations in brain and bone of a tauopathy mouse model of Alzheimer's disease.
Volume: 67
Pages: 148-158
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Publication
32194553 | J:311335
 
First Author: Barron MR
Year: 2020
Journal: Front Immunol
Title: Increasing Tau 4R Tau Levels Exacerbates Hippocampal Tau Hyperphosphorylation in the hTau Model of Tauopathy but Also Tau Dephosphorylation Following Acute Systemic Inflammation.
Volume: 11
Pages: 293
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Publication
26058840 | J:225440
First Author: Whittington RA
Year: 2015
Journal: Neurobiol Aging
Title: Dexmedetomidine increases tau phosphorylation under normothermic conditions in vivo and in vitro.
Volume: 36
Issue: 8
Pages: 2414-28
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Publication
32858248 | J:299594
 
First Author: Rodriguez L
Year: 2020
Journal: Neurobiol Aging
Title: Tau modulates visual plasticity in adult and old mice.
Volume: 95
Pages: 214-224
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Publication
25524708 | J:219593
First Author: Papanikolopoulou K
Year: 2015
Journal: Hum Mol Genet
Title: Temporally distinct phosphorylations differentiate Tau-dependent learning deficits and premature mortality in Drosophila.
Volume: 24
Issue: 7
Pages: 2065-77
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Publication
30564087 | J:276319
 
First Author: Ojo JO
Year: 2018
Journal: Front Neurosci
Title: Disruption in Brain Phospholipid Content in a Humanized Tau Transgenic Model Following Repetitive Mild Traumatic Brain Injury.
Volume: 12
Pages: 893
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Publication
24987368 | J:312060
 
First Author: Zhang Y
Year: 2014
Journal: Front Aging Neurosci
Title: Silencing [Formula: see text] Rescues Tau Pathologies and Memory Deficits through Rescuing PP2A and Inhibiting GSK-3β Signaling in Human Tau Transgenic Mice.
Volume: 6
Pages: 123
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Publication
30641037 | J:276274
 
First Author: Gratuze M
Year: 2019
Journal: Brain Res
Title: The toxin MPTP generates similar cognitive and locomotor deficits in hTau and tau knock-out mice.
Volume: 1711
Pages: 106-114
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Publication
37009893 | J:334929
First Author: Khan KM
Year: 2023
Journal: Acta Neuropathol Commun
Title: Human tau-overexpressing mice recapitulate brainstem involvement and neuropsychiatric features of early Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 57
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Publication
35359570 | J:322798
 
First Author: Trease AJ
Year: 2022
Journal: Front Mol Neurosci
Title: Hyperphosphorylated Human Tau Accumulates at the Synapse, Localizing on Synaptic Mitochondrial Outer Membranes and Disrupting Respiration in a Mouse Model of Tauopathy.
Volume: 15
Pages: 852368
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Publication
19710325 | J:152310
First Author: Polydoro M
Year: 2009
Journal: J Neurosci
Title: Age-dependent impairment of cognitive and synaptic function in the htau mouse model of tau pathology.
Volume: 29
Issue: 34
Pages: 10741-9
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Publication
29311903 | J:275711
 
First Author: Ferguson SA
Year: 2017
Journal: Front Aging Neurosci
Title: Negative Impact of Female Sex on Outcomes from Repetitive Mild Traumatic Brain Injury in hTau Mice Is Age Dependent: A Chronic Effects of Neurotrauma Consortium Study.
Volume: 9
Pages: 416
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Publication
27167086 | J:235967
 
First Author: Geiszler PC
Year: 2016
Journal: Neuroscience
Title: Impaired burrowing is the most prominent behavioral deficit of aging htau mice.
Volume: 329
Pages: 98-111
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Publication
30197586 | J:281373
 
First Author: Rodriguez L
Year: 2018
Journal: Front Mol Neurosci
Title: Human Tau Expression Does Not Induce Mouse Retina Neurodegeneration, Suggesting Differential Toxicity of Tau in Brain vs. Retinal Neurons.
Volume: 11
Pages: 293
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Publication
22487860 | J:285249
First Author: Weinger JG
Year: 2012
Journal: J Neuropathol Exp Neurol
Title: Mice devoid of Tau have increased susceptibility to neuronal damage in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis.
Volume: 71
Issue: 5
Pages: 422-33
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Publication
23874981 | J:204389
First Author: Bharadwaj P
Year: 2013
Journal: PLoS One
Title: Increased dendritic spine density and tau expression are associated with individual differences in steroidal regulation of male sexual behavior.
Volume: 8
Issue: 7
Pages: e69672
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Publication
29669277 | J:271116
First Author: EspĂ­ndola SL
Year: 2018
Journal: Cell Rep
Title: Modulation of Tau Isoforms Imbalance Precludes Tau Pathology and Cognitive Decline in a Mouse Model of Tauopathy.
Volume: 23
Issue: 3
Pages: 709-715
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Publication
32982685 | J:313556
 
First Author: Neddens J
Year: 2020
Journal: Front Mol Neurosci
Title: Constant Levels of Tau Phosphorylation in the Brain of htau Mice.
Volume: 13
Pages: 136
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Publication
33519674 | J:329683
 
First Author: Zareba-Paslawska J
Year: 2020
Journal: Front Neurol
Title: Tau Isoform-Driven CBD Pathology Transmission in Oligodendrocytes in Humanized Tau Mice.
Volume: 11
Pages: 589471
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Publication
30846870 | J:275890
First Author: Zhang Y
Year: 2019
Journal: Sci Rep
Title: Subacute to chronic Alzheimer-like alterations after controlled cortical impact in human tau transgenic mice.
Volume: 9
Issue: 1
Pages: 3789
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Publication
31152932 | J:282885
 
First Author: Ryan B
Year: 2019
Journal: Neuroscience
Title: Plasma MicroRNAs Are Altered Early and Consistently in a Mouse Model of Tauopathy.
Volume: 411
Pages: 164-176
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Publication
35334439 | J:325636
 
First Author: Guisle I
Year: 2022
Journal: Neurobiol Aging
Title: Sauna-like conditions or menthol treatment reduce tau phosphorylation through mild hyperthermia.
Volume: 113
Pages: 118-130
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Publication
27565300 | J:239559
 
First Author: Gratuze M
Year: 2016
Journal: Neurobiol Aging
Title: High-fat, high-sugar, and high-cholesterol consumption does not impact tau pathogenesis in a mouse model of Alzheimer's disease-like tau pathology.
Volume: 47
Pages: 71-73
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Publication
34093145 | J:314500
 
First Author: Cho JD
Year: 2021
Journal: Front Behav Neurosci
Title: Marked Mild Cognitive Deficits in Humanized Mouse Model of Alzheimer's-Type Tau Pathology.
Volume: 15
Pages: 634157
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Publication
15930395 | J:98717
First Author: Andorfer C
Year: 2005
Journal: J Neurosci
Title: Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.
Volume: 25
Issue: 22
Pages: 5446-54
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Publication
31771053 | J:285090
First Author: Davidowitz EJ
Year: 2020
Journal: J Alzheimers Dis
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