Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
184
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Mars LT |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Invariant NKT cells regulate experimental autoimmune encephalomyelitis and infiltrate the central nervous system in a CD1d-independent manner. |
Volume: |
181 |
Issue: |
4 |
Pages: |
2321-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mars LT |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Invariant NKT cells regulate the CD8 T cell response during Theiler's virus infection. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e87717 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mars LT |
Year: |
2009 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Invariant NKT cells inhibit development of the Th17 lineage. |
Volume: |
106 |
Issue: |
15 |
Pages: |
6238-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mars LT |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
CD8 T cell responses to myelin oligodendrocyte glycoprotein-derived peptides in humanized HLA-A*0201-transgenic mice. |
Volume: |
179 |
Issue: |
8 |
Pages: |
5090-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mars LT |
Year: |
2002 |
Journal: |
J Immunol |
Title: |
Cutting edge: V alpha 14-J alpha 281 NKT cells naturally regulate experimental autoimmune encephalomyelitis in nonobese diabetic mice. |
Volume: |
168 |
Issue: |
12 |
Pages: |
6007-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mars AE |
Year: |
1999 |
Journal: |
J Bacteriol |
Title: |
Conversion of 3-chlorocatechol by various catechol 2,3-dioxygenases and sequence analysis of the chlorocatechol dioxygenase region of Pseudomonas putida GJ31. |
Volume: |
181 |
Issue: |
4 |
Pages: |
1309-18 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
902
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
910
|
Fragment?: |
false |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang G |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
The Drosophila microtubule-associated protein mars stabilizes mitotic spindles by crosslinking microtubules through its N-terminal region. |
Volume: |
8 |
Issue: |
4 |
Pages: |
e60596 |
|
•
•
•
•
•
|
Publication |
First Author: |
Powell EM |
Year: |
2001 |
Journal: |
Neuron |
Title: |
Hepatocyte growth factor/scatter factor is a motogen for interneurons migrating from the ventral to dorsal telencephalon. |
Volume: |
30 |
Issue: |
1 |
Pages: |
79-89 |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Levi-Acobas F |
Year: |
2009 |
Journal: |
Genes Immun |
Title: |
Adaptive evolution of interferon-gamma in Glire lineage and evidence for a recent selective sweep in Mus. m. domesticus. |
Volume: |
10 |
Issue: |
4 |
Pages: |
297-308 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hao S |
Year: |
2010 |
Journal: |
Am J Pathol |
Title: |
tPA is a potent mitogen for renal interstitial fibroblasts: role of beta1 integrin/focal adhesion kinase signaling. |
Volume: |
177 |
Issue: |
3 |
Pages: |
1164-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin L |
Year: |
2014 |
Journal: |
Am J Pathol |
Title: |
Myeloid-derived tissue-type plasminogen activator promotes macrophage motility through FAK, Rac1, and NF-κB pathways. |
Volume: |
184 |
Issue: |
10 |
Pages: |
2757-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hu K |
Year: |
2007 |
Journal: |
J Clin Invest |
Title: |
Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling. |
Volume: |
117 |
Issue: |
12 |
Pages: |
3821-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Coudriet GM |
Year: |
2010 |
Journal: |
PLoS One |
Title: |
Hepatocyte growth factor modulates interleukin-6 production in bone marrow derived macrophages: implications for inflammatory mediated diseases. |
Volume: |
5 |
Issue: |
11 |
Pages: |
e15384 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bhave VS |
Year: |
2013 |
Journal: |
Am J Pathol |
Title: |
Regulation of liver growth by glypican 3, CD81, hedgehog, and Hhex. |
Volume: |
183 |
Issue: |
1 |
Pages: |
153-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koral K |
Year: |
2018 |
Journal: |
Am J Pathol |
Title: |
Lymphocyte-Specific Protein-1 Controls Sorafenib Sensitivity and Hepatocellular Proliferation through Extracellular Signal-Regulated Kinase 1/2 Activation. |
Volume: |
188 |
Issue: |
9 |
Pages: |
2074-2086 |
|
•
•
•
•
•
|
Publication |
First Author: |
Herdman C |
Year: |
2017 |
Journal: |
PLoS Genet |
Title: |
A unique enhancer boundary complex on the mouse ribosomal RNA genes persists after loss of Rrn3 or UBF and the inactivation of RNA polymerase I transcription. |
Volume: |
13 |
Issue: |
7 |
Pages: |
e1006899 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin L |
Year: |
2010 |
Journal: |
Am J Pathol |
Title: |
tPA activates LDL receptor-related protein 1-mediated mitogenic signaling involving the p90RSK and GSK3beta pathway. |
Volume: |
177 |
Issue: |
4 |
Pages: |
1687-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kang LI |
Year: |
2015 |
Journal: |
Lab Invest |
Title: |
Tissue-type plasminogen activator suppresses activated stellate cells through low-density lipoprotein receptor-related protein 1. |
Volume: |
95 |
Issue: |
10 |
Pages: |
1117-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang J |
Year: |
2002 |
Journal: |
J Clin Invest |
Title: |
Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy. |
Volume: |
110 |
Issue: |
10 |
Pages: |
1525-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hu K |
Year: |
2008 |
Journal: |
J Am Soc Nephrol |
Title: |
tPA protects renal interstitial fibroblasts and myofibroblasts from apoptosis. |
Volume: |
19 |
Issue: |
3 |
Pages: |
503-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hamdane N |
Year: |
2015 |
Journal: |
Oncotarget |
Title: |
Depletion of the cisplatin targeted HMGB-box factor UBF selectively induces p53-independent apoptotic death in transformed cells. |
Volume: |
6 |
Issue: |
29 |
Pages: |
27519-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saxena A |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
Tc17 CD8+ T cells potentiate Th1-mediated autoimmune diabetes in a mouse model. |
Volume: |
189 |
Issue: |
6 |
Pages: |
3140-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Donthamsetty S |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Role of PINCH and its partner tumor suppressor Rsu-1 in regulating liver size and tumorigenesis. |
Volume: |
8 |
Issue: |
9 |
Pages: |
e74625 |
|
•
•
•
•
•
|
Publication |
First Author: |
Griseri T |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
Invariant NKT cells exacerbate type 1 diabetes induced by CD8 T cells. |
Volume: |
175 |
Issue: |
4 |
Pages: |
2091-101 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bae MH |
Year: |
2010 |
Journal: |
Exp Neurol |
Title: |
Hepatocyte growth factor (HGF) modulates GABAergic inhibition and seizure susceptibility. |
Volume: |
221 |
Issue: |
1 |
Pages: |
129-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cabarrocas J |
Year: |
2004 |
Journal: |
J Autoimmun |
Title: |
A transgenic mouse model for T-cell ignorance of a glial autoantigen. |
Volume: |
22 |
Issue: |
3 |
Pages: |
179-89 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Saxena A |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Cutting edge: Multiple sclerosis-like lesions induced by effector CD8 T cells recognizing a sequestered antigen on oligodendrocytes. |
Volume: |
181 |
Issue: |
3 |
Pages: |
1617-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Donthamsetty S |
Year: |
2010 |
Journal: |
Toxicol Sci |
Title: |
Liver-specific ablation of integrin-linked kinase in mice results in enhanced and prolonged cell proliferation and hepatomegaly after phenobarbital administration. |
Volume: |
113 |
Issue: |
2 |
Pages: |
358-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsagianni A |
Year: |
2018 |
Journal: |
Am J Pathol |
Title: |
Combined Systemic Disruption of MET and Epidermal Growth Factor Receptor Signaling Causes Liver Failure in Normal Mice. |
Volume: |
188 |
Issue: |
10 |
Pages: |
2223-2235 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tremblay MG |
Year: |
2022 |
Journal: |
PLoS Genet |
Title: |
Ribosomal DNA promoter recognition is determined in vivo by cooperation between UBTF1 and SL1 and is compromised in the UBTF-E210K neuroregression syndrome. |
Volume: |
18 |
Issue: |
2 |
Pages: |
e1009644 |
|
•
•
•
•
•
|
Publication |
First Author: |
Serre L |
Year: |
2017 |
Journal: |
J Immunol |
Title: |
Thymic-Specific Serine Protease Limits Central Tolerance and Exacerbates Experimental Autoimmune Encephalomyelitis. |
Volume: |
199 |
Issue: |
11 |
Pages: |
3748-3756 |
|
•
•
•
•
•
|
Publication |
First Author: |
Duarte J |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
T cell apoptosis and induction of Foxp3+ regulatory T cells underlie the therapeutic efficacy of CD4 blockade in experimental autoimmune encephalomyelitis. |
Volume: |
189 |
Issue: |
4 |
Pages: |
1680-8 |
|
•
•
•
•
•
|
Allele |
Name: |
regulatory region 150; targeted mutation 1.1, Eric Pinaud |
Allele Type: |
Targeted |
Attribute String: |
Modified regulatory region |
|
•
•
•
•
•
|
Publication |
First Author: |
Proto JD |
Year: |
2015 |
Journal: |
Cell Death Dis |
Title: |
NF-κB inhibition reveals a novel role for HGF during skeletal muscle repair. |
Volume: |
6 |
|
Pages: |
e1730 |
|
•
•
•
•
•
|
Publication |
First Author: |
Krishnamoorthy G |
Year: |
2009 |
Journal: |
Nat Med |
Title: |
Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis. |
Volume: |
15 |
Issue: |
6 |
Pages: |
626-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lucca LE |
Year: |
2016 |
Journal: |
Eur J Immunol |
Title: |
Myelin oligodendrocyte glycoprotein induces incomplete tolerance of CD4(+) TÂ cells specific for both a myelin and a neuronal self-antigen in mice. |
Volume: |
46 |
Issue: |
9 |
Pages: |
2247-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gkretsi V |
Year: |
2008 |
Journal: |
Hepatology |
Title: |
Liver-specific ablation of integrin-linked kinase in mice results in abnormal histology, enhanced cell proliferation, and hepatomegaly. |
Volume: |
48 |
Issue: |
6 |
Pages: |
1932-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bhattarai Y |
Year: |
2020 |
Journal: |
iScience |
Title: |
Bacterially Derived Tryptamine Increases Mucus Release by Activating a Host Receptor in a Mouse Model of Inflammatory Bowel Disease. |
Volume: |
23 |
Issue: |
12 |
Pages: |
101798 |
|
•
•
•
•
•
|
Publication |
First Author: |
Coudriet GM |
Year: |
2019 |
Journal: |
Am J Pathol |
Title: |
A Noncanonical Role for Plasminogen Activator Inhibitor Type 1 in Obesity-Induced Diabetes. |
Volume: |
189 |
Issue: |
7 |
Pages: |
1413-1422 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cabarrocas J |
Year: |
2006 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage. |
Volume: |
103 |
Issue: |
22 |
Pages: |
8453-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Delarasse C |
Year: |
2003 |
Journal: |
J Clin Invest |
Title: |
Myelin/oligodendrocyte glycoprotein-deficient (MOG-deficient) mice reveal lack of immune tolerance to MOG in wild-type mice. |
Volume: |
112 |
Issue: |
4 |
Pages: |
544-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Blanquart E |
Year: |
2021 |
Journal: |
J Allergy Clin Immunol |
Title: |
Targeting androgen signaling in ILC2s protects from IL-33-driven lung inflammation, independently of KLRG1. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Seo J |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Nuclear matrix binding regulates SATB1-mediated transcriptional repression. |
Volume: |
280 |
Issue: |
26 |
Pages: |
24600-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marquet M |
Year: |
2014 |
Journal: |
J Immunol |
Title: |
The Eμ enhancer region influences H chain expression and B cell fate without impacting IgVH repertoire and immune response in vivo. |
Volume: |
193 |
Issue: |
3 |
Pages: |
1171-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saintamand A |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
E(μ) and 3'RR IgH enhancers show hierarchic unilateral dependence in mature B-cells. |
Volume: |
7 |
Issue: |
1 |
Pages: |
442 |
|
•
•
•
•
•
|
Publication |
First Author: |
Olonisakin TF |
Year: |
2021 |
Journal: |
J Clin Invest |
Title: |
Stressed erythrophagocytosis induces immunosuppression during sepsis through heme-mediated STAT1 dysregulation. |
Volume: |
131 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Greally JM |
Year: |
1997 |
Journal: |
Mamm Genome |
Title: |
Matrix-attachment regions in the mouse chromosome 7F imprinted domain. |
Volume: |
8 |
Issue: |
11 |
Pages: |
805-10 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
808
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
808
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
606
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
303
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
808
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
758
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
758
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Bennett D |
Year: |
2006 |
Journal: |
J Mol Biol |
Title: |
Towards a comprehensive analysis of the protein phosphatase 1 interactome in Drosophila. |
Volume: |
364 |
Issue: |
2 |
Pages: |
196-212 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents the SAPAP family, whose members include mars from fruit flies and disks large-associated proteins from vertebrates.Mars binds to microtubules and protein phosphatase 1. It is involved in cell signalling, mitotic spindle organisation and regulation of mitotic cell cycle [, ]. It is essential for the early development of Drosophila embryos []. Disks large-associated proteins are synaptic proteins that may play several roles in the molecular organisation of synapses and neuronal cell signalling [, ]. |
|
•
•
•
•
•
|
Publication |
First Author: |
Avramova Z |
Year: |
1992 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Matrix attachment sites in the murine alpha-globin gene. |
Volume: |
182 |
Issue: |
1 |
Pages: |
78-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Forrester WC |
Year: |
1994 |
Journal: |
Science |
Title: |
Dependence of enhancer-mediated transcription of the immunoglobulin mu gene on nuclear matrix attachment regions. |
Volume: |
265 |
Issue: |
5176 |
Pages: |
1221-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
McKnight RA |
Year: |
1996 |
Journal: |
Mol Reprod Dev |
Title: |
Severe position effects imposed on a 1 kb mouse whey acidic protein gene promoter are overcome by heterologous matrix attachment regions. |
Volume: |
44 |
Issue: |
2 |
Pages: |
179-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weber M |
Year: |
2003 |
Journal: |
Mol Cell Biol |
Title: |
Genomic imprinting controls matrix attachment regions in the Igf2 gene. |
Volume: |
23 |
Issue: |
24 |
Pages: |
8953-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Segalin C |
Year: |
2021 |
Journal: |
Elife |
Title: |
The Mouse Action Recognition System (MARS) software pipeline for automated analysis of social behaviors in mice. |
Volume: |
10 |
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
992
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1059
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
457
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
975
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
74
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
244
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
266
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
903
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
109
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
122
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
285
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
68
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Dobreva G |
Year: |
2003 |
Journal: |
Genes Dev |
Title: |
SUMO modification of a novel MAR-binding protein, SATB2, modulates immunoglobulin mu gene expression. |
Volume: |
17 |
Issue: |
24 |
Pages: |
3048-61 |
|
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•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1060
|
Fragment?: |
false |
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•
•
•
•
|
Publication |
First Author: |
Pavan Kumar P |
Year: |
2006 |
Journal: |
Mol Cell |
Title: |
Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo. |
Volume: |
22 |
Issue: |
2 |
Pages: |
231-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zarate YA |
Year: |
2017 |
Journal: |
Clin Genet |
Title: |
Genotype and phenotype in 12 additional individuals with SATB2-associated syndrome. |
Volume: |
92 |
Issue: |
4 |
Pages: |
423-429 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zarate YA |
Year: |
2017 |
Journal: |
Am J Med Genet A |
Title: |
SATB2-associated syndrome: Mechanisms, phenotype, and practical recommendations. |
Volume: |
173 |
Issue: |
2 |
Pages: |
327-337 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sunkara KP |
Year: |
2018 |
Journal: |
Biomed Pharmacother |
Title: |
Functional relevance of SATB1 in immune regulation and tumorigenesis. |
Volume: |
104 |
|
Pages: |
87-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Frömberg A |
Year: |
2018 |
Journal: |
Cancer Lett |
Title: |
The Special AT-rich Sequence Binding Protein 1 (SATB1) and its role in solid tumors. |
Volume: |
417 |
|
Pages: |
96-111 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry includes SATB1/2 from animals. SATB1 is a global gene regulator that acts as a "docking site"for several chromatin remodeling enzymes and recruits corepressors (HDACs) or coactivators (HATs) directly to promoters []. SATB1 can bind DNA specifically to the consensus SATB1-binding sequence (CSBS) consisting of two 5'-TAATA-3' half-sites that are arranged as inverted repeats flanking a central cytosine or guanine. It can also bind DNA non-specifically []. SATB1 has been shown to bind to the nuclear matrix attachment regions (MARs) of the immunoglobulin heavy chain intronic enhancer [], while SATB2 has been shown to bind to the MARs of the endogenous immunoglobulin micro locus in pre-B cells and enhances gene expression [].SATB1 is an identified oncogene, its increased expression is associated with poor prognosis in many cancers []. Mutations in the SATB2 gene cause SATB2-associated syndrome (SAS), characterised by developmental delay/intellectual disability with absent or limited speech development, craniofacial abnormalities, behavioral problems, dysmorphic features, and palatal and dental abnormalities [, ]. |
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•
•
•
•
•
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Publication |
First Author: |
Le Noir S |
Year: |
2017 |
Journal: |
Oncotarget |
Title: |
The IgH locus 3' cis-regulatory super-enhancer co-opts AID for allelic transvection. |
Volume: |
8 |
Issue: |
8 |
Pages: |
12929-12940 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang J |
Year: |
2016 |
Journal: |
Life Sci Space Res (Amst) |
Title: |
Lessons learned using different mouse models during space radiation-induced lung tumorigenesis experiments. |
Volume: |
9 |
|
Pages: |
48-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wiersma EJ |
Year: |
1999 |
Journal: |
J Biol Chem |
Title: |
Role of the intronic elements in the endogenous immunoglobulin heavy chain locus. Either the matrix attachment regions or the core enhancer is sufficient to maintain expression. |
Volume: |
274 |
Issue: |
8 |
Pages: |
4858-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Martins RP |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
Nuclear matrix interactions at the human protamine domain: a working model of potentiation. |
Volume: |
279 |
Issue: |
50 |
Pages: |
51862-8 |
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•
•
•
•
•
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