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Search results 1 to 100 out of 397 for Mavs

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Hits by Pathway

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Type Details Score
Gene
57506 | MAVS
Type: gene
Organism: human
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Gene
618508 | MAVS
Type: gene
Organism: cattle
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Gene
422936 | MAVS
Type: gene
Organism: chicken
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Gene
562867 | mavs
Type: gene
Organism: zebrafish
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Gene
717616 | MAVS
Type: gene
Organism: macaque, rhesus
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Gene
100485829 | mavs
Type: gene
Organism: frog, western clawed
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Gene
311430 | Mavs
Type: gene
Organism: rat
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Gene
485789 | MAVS
Type: gene
Organism: dog, domestic
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Gene
470026 | MAVS
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:2444773 | Mavs
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
31968249 | J:287701
First Author: Zhang W
Year: 2020
Journal: Cell Rep
Title: The Mitochondrial Protein MAVS Stabilizes p53 to Suppress Tumorigenesis.
Volume: 30
Issue: 3
Pages: 725-738.e4
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Publication
30249647 | J:266385
First Author: Plantamura E
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype.
Volume: 115
Issue: 41
Pages: 10404-10409
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Publication
23582325 | J:197368
First Author: Subramanian N
Year: 2013
Journal: Cell
Title: The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation.
Volume: 153
Issue: 2
Pages: 348-61
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Publication
26183716 | J:224454
 
First Author: Shi Y
Year: 2015
Journal: Nat Commun
Title: An autoinhibitory mechanism modulates MAVS activity in antiviral innate immune response.
Volume: 6
Pages: 7811
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Publication
16713980 | J:110905
First Author: Sun Q
Year: 2006
Journal: Immunity
Title: The specific and essential role of MAVS in antiviral innate immune responses.
Volume: 24
Issue: 5
Pages: 633-42
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Publication
31461653 | J:284075
First Author: Song N
Year: 2019
Journal: Cell Rep
Title: MAVS O-GlcNAcylation Is Essential for Host Antiviral Immunity against Lethal RNA Viruses.
Volume: 28
Issue: 9
Pages: 2386-2396.e5
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Publication
27899525 | J:259450
First Author: Buskiewicz IA
Year: 2016
Journal: Sci Signal
Title: Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus.
Volume: 9
Issue: 456
Pages: ra115
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Publication
30267893 | J:295651
 
First Author: Zhang P
Year: 2018
Journal: Microb Pathog
Title: Critical role of MAVS in the protection against Clostridium difficile-induced colitis.
Volume: 125
Pages: 306-312
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Publication
26246171 | J:225000
 
First Author: Yoo YS
Year: 2015
Journal: Nat Commun
Title: The mitochondrial ubiquitin ligase MARCH5 resolves MAVS aggregates during antiviral signalling.
Volume: 6
Pages: 7910
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Publication
27438769 | J:258668
First Author: Zhang LJ
Year: 2016
Journal: Immunity
Title: Antimicrobial Peptide LL37 and MAVS Signaling Drive Interferon-β Production by Epidermal Keratinocytes during Skin Injury.
Volume: 45
Issue: 1
Pages: 119-30
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Publication
37563140 | J:338972
First Author: Li J
Year: 2023
Journal: Nat Commun
Title: WDR77 inhibits prion-like aggregation of MAVS to limit antiviral innate immune response.
Volume: 14
Issue: 1
Pages: 4824
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Publication
28141795 | J:259778
First Author: Cheng J
Year: 2017
Journal: Cell Death Differ
Title: Autophagy regulates MAVS signaling activation in a phosphorylation-dependent manner in microglia.
Volume: 24
Issue: 2
Pages: 276-287
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Publication
31681326 | J:281348
 
First Author: Sun W
Year: 2019
Journal: Front Immunol
Title: Antiviral Adaptor MAVS Promotes Murine Lupus With a B Cell Autonomous Role.
Volume: 10
Pages: 2452
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Publication
35844503 | J:342242
 
First Author: Wang Q
Year: 2022
Journal: Front Immunol
Title: Reduced Immunity Regulator MAVS Contributes to Non-Hypertrophic Cardiac Dysfunction by Disturbing Energy Metabolism and Mitochondrial Homeostasis.
Volume: 13
Pages: 919038
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Publication
31390091 | J:280922
First Author: Zhu W
Year: 2019
Journal: EMBO J
Title: TRAF3IP3 mediates the recruitment of TRAF3 to MAVS for antiviral innate immunity.
Volume: 38
Issue: 18
Pages: e102075
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Publication
23951545 | J:207797
 
First Author: Liu S
Year: 2013
Journal: Elife
Title: MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades.
Volume: 2
Pages: e00785
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Publication
23754752 | J:204562
First Author: Guan K
Year: 2013
Journal: Mol Cell Biol
Title: MAVS regulates apoptotic cell death by decreasing K48-linked ubiquitination of voltage-dependent anion channel 1.
Volume: 33
Issue: 16
Pages: 3137-49
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Publication
30460894 | J:326730
   
First Author: Ding S
Year: 2018
Journal: Elife
Title: Rotavirus VP3 targets MAVS for degradation to inhibit type III interferon expression in intestinal epithelial cells.
Volume: 7
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Publication
33139700 | J:297834
First Author: Zhang ZD
Year: 2020
Journal: Nat Commun
Title: RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA.
Volume: 11
Issue: 1
Pages: 5536
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Publication
19881509 | J:157738
First Author: You F
Year: 2009
Journal: Nat Immunol
Title: PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4.
Volume: 10
Issue: 12
Pages: 1300-8
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Publication
25847972 | J:243899
First Author: Guan K
Year: 2015
Journal: J Immunol
Title: MAVS Promotes Inflammasome Activation by Targeting ASC for K63-Linked Ubiquitination via the E3 Ligase TRAF3.
Volume: 194
Issue: 10
Pages: 4880-90
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Publication
31242236 | J:340293
First Author: Roe K
Year: 2019
Journal: PLoS One
Title: Dendritic cell-associated MAVS is required to control West Nile virus replication and ensuing humoral immune responses.
Volume: 14
Issue: 6
Pages: e0218928
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Publication
33123150 | J:324389
 
First Author: Paulsen M
Year: 2020
Journal: Front Immunol
Title: MAVS Deficiency Is Associated With a Reduced T Cell Response Upon Secondary RSV Infection in Mice.
Volume: 11
Pages: 572747
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Publication
28094802 | J:273997
 
First Author: Da Costa A
Year: 2017
Journal: Sci Rep
Title: Extrinsic MAVS signaling is critical for Treg maintenance of Foxp3 expression following acute flavivirus infection.
Volume: 7
Pages: 40720
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Publication
28410401 | J:246918
First Author: Downey J
Year: 2017
Journal: PLoS Pathog
Title: RIPK3 interacts with MAVS to regulate type I IFN-mediated immunity to Influenza A virus infection.
Volume: 13
Issue: 4
Pages: e1006326
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Publication
27226371 | J:234548
First Author: Zhao J
Year: 2016
Journal: J Virol
Title: MAVS Expressed by Hematopoietic Cells Is Critical for Control of West Nile Virus Infection and Pathogenesis.
Volume: 90
Issue: 16
Pages: 7098-108
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Publication
26588843 | J:245910
First Author: Bender S
Year: 2015
Journal: PLoS Pathog
Title: Activation of Type I and III Interferon Response by Mitochondrial and Peroxisomal MAVS and Inhibition by Hepatitis C Virus.
Volume: 11
Issue: 11
Pages: e1005264
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Publication
27992402 | J:275178
First Author: Liu B
Year: 2017
Journal: Nat Immunol
Title: The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination.
Volume: 18
Issue: 2
Pages: 214-224
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Publication
31956894 | J:292357
First Author: Bajad P
Year: 2020
Journal: Nucleic Acids Res
Title: An internal deletion of ADAR rescued by MAVS deficiency leads to a minute phenotype.
Volume: 48
Issue: 6
Pages: 3286-3303
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Publication
35108347 | J:322525
First Author: Varese A
Year: 2022
Journal: PLoS Pathog
Title: Type I interferons and MAVS signaling are necessary for tissue resident memory CD8+ T cell responses to RSV infection.
Volume: 18
Issue: 2
Pages: e1010272
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Publication
23300459 | J:195894
First Author: Lazear HM
Year: 2013
Journal: PLoS Pathog
Title: IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling.
Volume: 9
Issue: 1
Pages: e1003118
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Publication
35584192 | J:325123
First Author: Hum NR
Year: 2022
Journal: PLoS Pathog
Title: MAVS mediates a protective immune response in the brain to Rift Valley fever virus.
Volume: 18
Issue: 5
Pages: e1010231
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Publication
18780793 | J:139074
First Author: Bhoj VG
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: MAVS and MyD88 are essential for innate immunity but not cytotoxic T lymphocyte response against respiratory syncytial virus.
Volume: 105
Issue: 37
Pages: 14046-51
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Publication
23499490 | J:196200
First Author: Mukherjee P
Year: 2013
Journal: Immunity
Title: Activation of the innate signaling molecule MAVS by bunyavirus infection upregulates the adaptor protein SARM1, leading to neuronal death.
Volume: 38
Issue: 4
Pages: 705-16
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Publication
28077630 | J:239520
 
First Author: Luo H
Year: 2017
Journal: J Virol
Title: MAVS Is Essential for Primary CD4+ T Cell Immunity but Not for Recall T Cell Responses following an Attenuated West Nile Virus Infection.
Volume: 91
Issue: 6
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GO Term
GO:0039545 | symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
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Publication
29117566 | J:254874
First Author: Loetsch C
Year: 2017
Journal: Cell Rep
Title: Cytosolic Recognition of RNA Drives the Immune Response to Heterologous Erythrocytes.
Volume: 21
Issue: 6
Pages: 1624-1638
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Publication
27633528 | J:323366
First Author: Hirai-Yuki A
Year: 2016
Journal: Science
Title: MAVS-dependent host species range and pathogenicity of human hepatitis A virus.
Volume: 353
Issue: 6307
Pages: 1541-1545
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Ontology Term
- | Inhibition of host MAVS by virus
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Publication
24037184 | J:257328
First Author: Liu Y
Year: 2014
Journal: Cell Mol Immunol
Title: The interaction between the helicase DHX33 and IPS-1 as a novel pathway to sense double-stranded RNA and RNA viruses in myeloid dendritic cells.
Volume: 11
Issue: 1
Pages: 49-57
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Publication
25981042 | J:228452
First Author: Oshiumi H
Year: 2015
Journal: Cell Rep
Title: DDX60 Is Involved in RIG-I-Dependent and Independent Antiviral Responses, and Its Function Is Attenuated by Virus-Induced EGFR Activation.
Volume: 11
Issue: 8
Pages: 1193-207
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Publication
31996459 | J:285619
First Author: Zhou D
Year: 2020
Journal: J Immunol
Title: The Japanese Encephalitis Virus NS1' Protein Inhibits Type I IFN Production by Targeting MAVS.
Volume: 204
Issue: 5
Pages: 1287-1298
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Publication
25953917 | J:321094
First Author: Deng J
Year: 2015
Journal: J Gen Virol
Title: Mitochondrial antiviral-signalling protein plays an essential role in host immunity against human metapneumovirus.
Volume: 96
Issue: 8
Pages: 2104-2113
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Publication
19701189 | J:152795
First Author: Sabbah A
Year: 2009
Journal: Nat Immunol
Title: Activation of innate immune antiviral responses by Nod2.
Volume: 10
Issue: 10
Pages: 1073-80
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Publication
28207838 | J:245533
First Author: Hee JS
Year: 2017
Journal: PLoS One
Title: Viperin interaction with mitochondrial antiviral signaling protein (MAVS) limits viperin-mediated inhibition of the interferon response in macrophages.
Volume: 12
Issue: 2
Pages: e0172236
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Publication
21960441 | J:177458
First Author: Li XD
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis.
Volume: 108
Issue: 42
Pages: 17390-5
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Publication
34016972 | J:319808
First Author: Hou J
Year: 2021
Journal: Nat Commun
Title: USP18 positively regulates innate antiviral immunity by promoting K63-linked polyubiquitination of MAVS.
Volume: 12
Issue: 1
Pages: 2970
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Publication
24391214 | J:207614
First Author: El Maadidi S
Year: 2014
Journal: J Immunol
Title: A novel mitochondrial MAVS/Caspase-8 platform links RNA virus-induced innate antiviral signaling to Bax/Bak-independent apoptosis.
Volume: 192
Issue: 3
Pages: 1171-83
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Publication
30199535 | J:265496
First Author: Gonzalez-Quintial R
Year: 2018
Journal: PLoS One
Title: Lupus acceleration by a MAVS-activating RNA virus requires endosomal TLR signaling and host genetic predisposition.
Volume: 13
Issue: 9
Pages: e0203118
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Publication
24530055 | J:209917
First Author: Funabiki M
Year: 2014
Journal: Immunity
Title: Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.
Volume: 40
Issue: 2
Pages: 199-212
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Publication
27438481 | J:245833
First Author: Kandasamy M
Year: 2016
Journal: PLoS Pathog
Title: RIG-I Signaling Is Critical for Efficient Polyfunctional T Cell Responses during Influenza Virus Infection.
Volume: 12
Issue: 7
Pages: e1005754
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Publication
25897172 | J:222697
First Author: Goritzka M
Year: 2015
Journal: J Exp Med
Title: Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes.
Volume: 212
Issue: 5
Pages: 699-714
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Publication
30878284 | J:274136
First Author: Ning X
Year: 2019
Journal: Mol Cell
Title: Apoptotic Caspases Suppress Type I Interferon Production via the Cleavage of cGAS, MAVS, and IRF3.
Volume: 74
Issue: 1
Pages: 19-31.e7
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Publication
27102485 | J:232473
First Author: Pillai PS
Year: 2016
Journal: Science
Title: Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease.
Volume: 352
Issue: 6284
Pages: 463-6
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Publication
37703370 | J:340288
First Author: Ingle H
Year: 2023
Journal: Sci Adv
Title: IFN-λ derived from nonsusceptible enterocytes acts on tuft cells to limit persistent norovirus.
Volume: 9
Issue: 37
Pages: eadi2562
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Publication
28594325 | J:257113
   
First Author: Liu W
Year: 2017
Journal: Elife
Title: Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses.
Volume: 6
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Publication
32324863 | J:294929
 
First Author: Zhu Q
Year: 2020
Journal: J Exp Med
Title: TRIM24 facilitates antiviral immunity through mediating K63-linked TRAF3 ubiquitination.
Volume: 217
Issue: 7
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Publication
31792184 | J:282792
First Author: Sankowski R
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Endogenous retroviruses are associated with hippocampus-based memory impairment.
Volume: 116
Issue: 51
Pages: 25982-25990
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Publication
30115978 | J:278069
First Author: Schulze S
Year: 2018
Journal: Sci Rep
Title: Cytosolic nucleic acid sensors of the innate immune system promote liver regeneration after partial hepatectomy.
Volume: 8
Issue: 1
Pages: 12271
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Publication
30410068 | J:286922
First Author: Liuyu T
Year: 2019
Journal: Cell Res
Title: Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS.
Volume: 29
Issue: 1
Pages: 67-79
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Publication
19690333 | J:259230
First Author: Yasukawa K
Year: 2009
Journal: Sci Signal
Title: Mitofusin 2 inhibits mitochondrial antiviral signaling.
Volume: 2
Issue: 84
Pages: ra47
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Publication
21187438 | J:168914
First Author: Broquet AH
Year: 2011
Journal: J Immunol
Title: RIG-I/MDA5/MAVS are required to signal a protective IFN response in rotavirus-infected intestinal epithelium.
Volume: 186
Issue: 3
Pages: 1618-26
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Publication
25609814 | J:222597
First Author: Anggakusuma
Year: 2015
Journal: J Virol
Title: Control of hepatitis C virus replication in mouse liver-derived cells by MAVS-dependent production of type I and type III interferons.
Volume: 89
Issue: 7
Pages: 3833-45
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Publication
23408632 | J:197207
First Author: Ermler ME
Year: 2013
Journal: J Virol
Title: RNA helicase signaling is critical for type i interferon production and protection against Rift Valley fever virus during mucosal challenge.
Volume: 87
Issue: 9
Pages: 4846-60
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Publication
20451243 | J:167950
First Author: Dixit E
Year: 2010
Journal: Cell
Title: Peroxisomes are signaling platforms for antiviral innate immunity.
Volume: 141
Issue: 4
Pages: 668-81
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Publication
33087405 | J:300722
First Author: Wang X
Year: 2020
Journal: J Immunol
Title: MDA5 Is an Essential Sensor of a Pathogen-Associated Molecular Pattern Associated with Vitality That Is Necessary for Host Resistance against Aspergillus fumigatus.
Volume: 205
Issue: 11
Pages: 3058-3070
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Publication
27736772 | J:242996
 
First Author: Choi YB
Year: 2017
Journal: Mol Cell Biol
Title: TAX1BP1 Restrains Virus-Induced Apoptosis by Facilitating Itch-Mediated Degradation of the Mitochondrial Adaptor MAVS.
Volume: 37
Issue: 1
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Publication
24990442 | J:217122
First Author: Allam R
Year: 2014
Journal: EMBO Rep
Title: Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming.
Volume: 15
Issue: 9
Pages: 982-90
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Publication
28100675 | J:240737
First Author: Dalet A
Year: 2017
Journal: EMBO J
Title: Protein synthesis inhibition and GADD34 control IFN-β heterogeneous expression in response to dsRNA.
Volume: 36
Issue: 6
Pages: 761-782
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Publication
19915568 | J:157877
First Author: Poeck H
Year: 2010
Journal: Nat Immunol
Title: Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production.
Volume: 11
Issue: 1
Pages: 63-9
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Publication
25456137 | J:265968
First Author: Mannion NM
Year: 2014
Journal: Cell Rep
Title: The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.
Volume: 9
Issue: 4
Pages: 1482-94
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Publication
21937652 | J:178555
First Author: Cotter CR
Year: 2011
Journal: J Virol
Title: The virion host shutoff protein of herpes simplex virus 1 blocks the replication-independent activation of NF-κB in dendritic cells in the absence of type I interferon signaling.
Volume: 85
Issue: 23
Pages: 12662-72
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Publication
24096085 | J:205999
First Author: Takaki H
Year: 2014
Journal: Mol Immunol
Title: MAVS-dependent IRF3/7 bypass of interferon β-induction restricts the response to measles infection in CD150Tg mouse bone marrow-derived dendritic cells.
Volume: 57
Issue: 2
Pages: 100-10
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Publication
29626090 | J:264014
First Author: Ramachandran B
Year: 2018
Journal: J Biol Chem
Title: A GTPase-activating protein-binding protein (G3BP1)/antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells.
Volume: 293
Issue: 21
Pages: 7942-7968
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Publication
26633895 | J:248539
First Author: Painter MM
Year: 2015
Journal: PLoS Pathog
Title: Antiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity.
Volume: 11
Issue: 12
Pages: e1005311
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Publication
24743949 | J:246220
First Author: Pinto AK
Year: 2014
Journal: PLoS Pathog
Title: Deficient IFN signaling by myeloid cells leads to MAVS-dependent virus-induced sepsis.
Volume: 10
Issue: 4
Pages: e1004086
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Protein Coding Gene
MGP_CAROLIEiJ_G0024326 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026528 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026492 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026467 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026504 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026247 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2444773 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026949 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025708 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026227 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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•
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Protein Coding Gene
MGP_DBA2J_G0026361 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
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Protein Coding Gene
MGP_FVBNJ_G0026325 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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•
•
•
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Protein Coding Gene
MGP_LPJ_G0026466 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0026345 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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•
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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