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Search results 1 to 100 out of 304 for Mbd3

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: Methyl-CpG-binding domain protein 3 (MBD3) is a transcriptional repressor and plays a role in gene silencing. It binds to DNA with a preference for sites containing methylated CpG dinucleotides but only as part of a complex [, ]. It forms a heterodimer with MBD2 []and is a component of the NuRD []and the MeCP1 []complexes.
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 285  
Fragment?: false
Publication
First Author: Saito M
Year: 2002
Journal: J Biol Chem
Title: The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2.
Volume: 277
Issue: 38
Pages: 35434-9
Publication
First Author: Kaji K
Year: 2006
Journal: Nat Cell Biol
Title: The NuRD component Mbd3 is required for pluripotency of embryonic stem cells.
Volume: 8
Issue: 3
Pages: 285-92
Publication    
First Author: Hainer SJ
Year: 2016
Journal: Elife
Title: DNA methylation directs genomic localization of Mbd2 and Mbd3 in embryonic stem cells.
Volume: 5
Publication
First Author: Hendrich B
Year: 2001
Journal: Genes Dev
Title: Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development.
Volume: 15
Issue: 6
Pages: 710-23
Publication
First Author: Datta J
Year: 2005
Journal: Cancer Res
Title: Physical and functional interaction of DNA methyltransferase 3A with Mbd3 and Brg1 in mouse lymphosarcoma cells.
Volume: 65
Issue: 23
Pages: 10891-900
Protein
Organism: Mus musculus/domesticus
Length: 185  
Fragment?: true
Publication
First Author: Feng Q
Year: 2002
Journal: Mol Cell Biol
Title: Identification and functional characterization of the p66/p68 components of the MeCP1 complex.
Volume: 22
Issue: 2
Pages: 536-46
Protein
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 72  
Fragment?: true
Publication
First Author: Tatematsu KI
Year: 2000
Journal: Genes Cells
Title: MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase.
Volume: 5
Issue: 8
Pages: 677-88
Publication
First Author: Cramer JM
Year: 2014
Journal: J Biol Chem
Title: Probing the dynamic distribution of bound states for methylcytosine-binding domains on DNA.
Volume: 289
Issue: 3
Pages: 1294-302
Publication
First Author: Aguilera C
Year: 2011
Journal: Nature
Title: c-Jun N-terminal phosphorylation antagonises recruitment of the Mbd3/NuRD repressor complex.
Volume: 469
Issue: 7329
Pages: 231-5
Publication
First Author: Loughran SJ
Year: 2017
Journal: J Exp Med
Title: Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program.
Volume: 214
Issue: 10
Pages: 3085-3104
Publication
First Author: Reese KJ
Year: 2007
Journal: PLoS Genet
Title: Maintenance of paternal methylation and repression of the imprinted H19 gene requires MBD3.
Volume: 3
Issue: 8
Pages: e137
Publication
First Author: Kim JJ
Year: 2012
Journal: J Biol Chem
Title: A novel regulatory factor recruits the nucleosome remodeling complex to wingless integrated (Wnt) signaling gene promoters in mouse embryonic stem cells.
Volume: 287
Issue: 49
Pages: 41103-17
Publication
First Author: Zhang Y
Year: 1999
Journal: Genes Dev
Title: Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.
Volume: 13
Issue: 15
Pages: 1924-35
Publication
First Author: Spensberger D
Year: 2008
Journal: Biochemistry
Title: Myeloid transforming protein Evi1 interacts with methyl-CpG binding domain protein 3 and inhibits in vitro histone deacetylation by Mbd3/Mi-2/NuRD.
Volume: 47
Issue: 24
Pages: 6418-26
Publication
First Author: Mor N
Year: 2018
Journal: Cell Stem Cell
Title: Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency.
Volume: 23
Issue: 3
Pages: 412-425.e10
Publication
First Author: Miller A
Year: 2016
Journal: Development
Title: Sall4 controls differentiation of pluripotent cells independently of the Nucleosome Remodelling and Deacetylation (NuRD) complex.
Volume: 143
Issue: 17
Pages: 3074-84
Publication
First Author: Tsuboi M
Year: 2018
Journal: Dev Cell
Title: Ubiquitination-Independent Repression of PRC1 Targets during Neuronal Fate Restriction in the Developing Mouse Neocortex.
Volume: 47
Issue: 6
Pages: 758-772.e5
Publication
First Author: Moon BS
Year: 2017
Journal: PLoS Biol
Title: Smek promotes corticogenesis through regulating Mbd3's stability and Mbd3/NuRD complex recruitment to genes associated with neurogenesis.
Volume: 15
Issue: 5
Pages: e2001220
Publication
First Author: Liang J
Year: 2008
Journal: Nat Cell Biol
Title: Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells.
Volume: 10
Issue: 6
Pages: 731-9
Publication
First Author: Hendrich B
Year: 1999
Journal: Mamm Genome
Title: Genomic structure and chromosomal mapping of the murine and human Mbd1, Mbd2, Mbd3, and Mbd4 genes.
Volume: 10
Issue: 9
Pages: 906-12
Publication
First Author: Le Guezennec X
Year: 2006
Journal: Mol Cell Biol
Title: MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.
Volume: 26
Issue: 3
Pages: 843-51
Publication
First Author: Hendrich B
Year: 1998
Journal: Mol Cell Biol
Title: Identification and characterization of a family of mammalian methyl-CpG binding proteins.
Volume: 18
Issue: 11
Pages: 6538-47
Publication  
First Author: Knock E
Year: 2015
Journal: Neural Dev
Title: The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex.
Volume: 10
Pages: 13
Publication
First Author: Kantor B
Year: 2003
Journal: Gene Expr Patterns
Title: Expression and localization of components of the histone deacetylases multiprotein repressory complexes in the mouse preimplantation embryo.
Volume: 3
Issue: 6
Pages: 697-702
Publication
First Author: Linke M
Year: 2013
Journal: Cytogenet Genome Res
Title: The impact of ovarian stimulation on the expression of candidate reprogramming genes in mouse preimplantation embryos.
Volume: 139
Issue: 2
Pages: 71-9
Publication  
First Author: Chen Y
Year: 2014
Journal: Front Genet
Title: Diversity of two forms of DNA methylation in the brain.
Volume: 5
Pages: 46
Publication
First Author: Gu P
Year: 2006
Journal: Mol Cell Biol
Title: Differential recruitment of methylated CpG binding domains by the orphan receptor GCNF initiates the repression and silencing of Oct4 expression.
Volume: 26
Issue: 24
Pages: 9471-83
Publication
First Author: Ohki I
Year: 2001
Journal: Cell
Title: Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA.
Volume: 105
Issue: 4
Pages: 487-97
Publication
First Author: Kaji K
Year: 2007
Journal: Development
Title: Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells.
Volume: 134
Issue: 6
Pages: 1123-32
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Luo M
Year: 2013
Journal: Stem Cells
Title: NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells.
Volume: 31
Issue: 7
Pages: 1278-86
Publication
First Author: Latos PA
Year: 2012
Journal: Biol Open
Title: NuRD-dependent DNA methylation prevents ES cells from accessing a trophectoderm fate.
Volume: 1
Issue: 4
Pages: 341-52
GXD Expression    
Probe: MGI:3703344
Assay Type: RT-PCR
Annotation Date: 2007-04-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160414
Stage: TS04
Assay Id: MGI:3703539
Age: embryonic day 3.5
Image: 5
Specimen Label: -/-, 3.5dpc
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3703344
Assay Type: RT-PCR
Annotation Date: 2007-04-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3703539
Age: embryonic day 4.5
Image: 5
Specimen Label: -/-, 4.5dpc
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:3838635
Assay Type: RT-PCR
Annotation Date: 2009-04-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:3839006
Age: embryonic day 0.5
Specimen Label: 1-cell
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3838635
Assay Type: RT-PCR
Annotation Date: 2009-04-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3839006
Age: embryonic day 1.0
Specimen Label: 2-cell
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3838635
Assay Type: RT-PCR
Annotation Date: 2009-04-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3839006
Age: embryonic day 2.0
Specimen Label: 4-cell
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3838635
Assay Type: RT-PCR
Annotation Date: 2009-04-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3839006
Age: embryonic day 3.0
Specimen Label: 16-cell
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289540
Age: embryonic day 1.5
Specimen Label: 2-cell-A1-1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289540
Age: embryonic day 1.5
Specimen Label: 2-cell-A1-2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289540
Age: embryonic day 1.5
Specimen Label: 2-cell-A2-1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289540
Age: embryonic day 1.5
Specimen Label: 2-cell-A2-2
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289540
Age: embryonic day 1.5
Specimen Label: 2-cell-B1-1
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289540
Age: embryonic day 1.5
Specimen Label: 2-cell-B1-2
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289540
Age: embryonic day 1.5
Specimen Label: 2-cell-B2-1
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289540
Age: embryonic day 1.5
Specimen Label: 2-cell-B2-2
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289540
Age: embryonic day 1.5
Specimen Label: 2-cell-C1-1
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289540
Age: embryonic day 1.5
Specimen Label: 2-cell-C1-2
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289540
Age: embryonic day 1.5
Specimen Label: 2-cell-C2-1
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289540
Age: embryonic day 1.5
Specimen Label: 2-cell-C2-2
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-A1-1
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-A1-2
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-A2-1
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-A2-2
Detected: true
Specimen Num: 16
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-A3-1
Detected: true
Specimen Num: 17
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-A3-2
Detected: true
Specimen Num: 18
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-A4-1
Detected: true
Specimen Num: 19
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-A4-2
Detected: true
Specimen Num: 20
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-B1-1
Detected: true
Specimen Num: 21
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-B1-2
Detected: true
Specimen Num: 22
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-B2-1
Detected: true
Specimen Num: 23
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-B2-2
Detected: true
Specimen Num: 24
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-B3-1
Detected: true
Specimen Num: 25
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-B3-2
Detected: true
Specimen Num: 26
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-B4-1
Detected: true
Specimen Num: 27
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-B4-2
Detected: true
Specimen Num: 28
GXD Expression      
Probe: MGI:5288916
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289540
Age: embryonic day 2.0
Specimen Label: 4-cell-C1-1
Detected: true
Specimen Num: 29