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Search results 1 to 100 out of 569 for Mc4r

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Type Details Score
Gene
4160 | MC4R
Type: gene
Organism: human
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Gene
281300 | MC4R
Type: gene
Organism: cattle
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Gene
428485 | MC4R
Type: gene
Organism: chicken
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Gene
286833 | mc4r
Type: gene
Organism: zebrafish
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Gene
698596 | MC4R
Type: gene
Organism: macaque, rhesus
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Gene
100486677 | mc4r
Type: gene
Organism: frog, western clawed
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Gene
25635 | Mc4r
Type: gene
Organism: rat
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Gene
483961 | MC4R
Type: gene
Organism: dog, domestic
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Gene
468556 | MC4R
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:99457 | Mc4r
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
   
Probe: MGI:3724354
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:3826219
Age: embryonic day 14.5
Image: Additional file 4 Mc4r
Specimen Label: Additional file 4 Mc4r
Detected: false
Specimen Num: 1
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Publication
33568756 | J:305716
First Author: Naser AA
Year: 2021
Journal: Sci Rep
Title: MC4R mutant mice develop ovarian teratomas.
Volume: 11
Issue: 1
Pages: 3483
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Publication
29031731 | J:262801
First Author: Collet TH
Year: 2017
Journal: Mol Metab
Title: Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency.
Volume: 6
Issue: 10
Pages: 1321-1329
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Publication
22100407 | J:179670
First Author: Vella KR
Year: 2011
Journal: Cell Metab
Title: NPY and MC4R signaling regulate thyroid hormone levels during fasting through both central and peripheral pathways.
Volume: 14
Issue: 6
Pages: 780-90
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Publication
29311635 | J:261694
First Author: Siljee JE
Year: 2018
Journal: Nat Genet
Title: Subcellular localization of MC4R with ADCY3 at neuronal primary cilia underlies a common pathway for genetic predisposition to obesity.
Volume: 50
Issue: 2
Pages: 180-185
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Publication
33052459 | J:305644
First Author: de Souza Cordeiro LM
Year: 2021
Journal: Diabetologia
Title: Hypothalamic MC4R regulates glucose homeostasis through adrenaline-mediated control of glucose reabsorption via renal GLUT2 in mice.
Volume: 64
Issue: 1
Pages: 181-194
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Publication
21239438 | J:173880
First Author: Srisai D
Year: 2011
Journal: Endocrinology
Title: Characterization of the hyperphagic response to dietary fat in the MC4R knockout mouse.
Volume: 152
Issue: 3
Pages: 890-902
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Publication
34646010 | J:326176
First Author: Krause WC
Year: 2021
Journal: Nature
Title: Oestrogen engages brain MC4R signalling to drive physical activity in female mice.
Volume: 599
Issue: 7883
Pages: 131-135
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Publication
29407371 | J:260975
 
First Author: Katidou M
Year: 2018
Journal: Mol Cell Neurosci
Title: G-protein coupled receptors Mc4r and Drd1a can serve as surrogate odorant receptors in mouse olfactory sensory neurons.
Volume: 88
Pages: 138-147
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Publication
29030576 | J:255569
First Author: Doshi S
Year: 2017
Journal: Sci Rep
Title: Genetic induction of hypometabolism by ablation of MC4R does not suppress ALS-like phenotypes in the G93A mutant SOD1 mouse model.
Volume: 7
Issue: 1
Pages: 13150
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Publication
31990961 | J:285412
First Author: Matsumoto M
Year: 2020
Journal: PLoS One
Title: Acetyl-CoA carboxylase 1 and 2 inhibition ameliorates steatosis and hepatic fibrosis in a MC4R knockout murine model of nonalcoholic steatohepatitis.
Volume: 15
Issue: 1
Pages: e0228212
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Publication
37127675 | J:335434
First Author: Seki S
Year: 2023
Journal: Sci Rep
Title: The Mc4r gene is responsible for the development of experimentally induced testicular teratomas.
Volume: 13
Issue: 1
Pages: 6756
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Publication
15950372 | J:99300
First Author: Daniel PB
Year: 2005
Journal: Mol Cell Endocrinol
Title: 1 kb of 5' flanking sequence from mouse MC4R gene is sufficient for tissue specific expression in a transgenic mouse.
Volume: 239
Issue: 1-2
Pages: 63-71
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Publication
34823066 | J:330365
 
First Author: Singh U
Year: 2022
Journal: Mol Metab
Title: Neuroanatomical organization and functional roles of PVN MC4R pathways in physiological and behavioral regulations.
Volume: 55
Pages: 101401
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Publication
21460229 | J:174243
First Author: Overton JD
Year: 2011
Journal: J Biol Chem
Title: Mahoganoid and mahogany mutations rectify the obesity of the yellow mouse by effects on endosomal traffic of MC4R protein.
Volume: 286
Issue: 21
Pages: 18914-29
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GXD Expression
GXD Expression
   
Probe: MGI:6177674
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190771
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Mc4r
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6177674
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190771
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Mc4r
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6177674
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190771
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Mc4r
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6177674
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190771
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Mc4r
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6177674
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190771
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Mc4r
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6177674
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190771
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Mc4r
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6177674
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190771
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Mc4r
Detected: true
Specimen Num: 7
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Publication
35344393 | J:327594
First Author: Matsumura S
Year: 2022
Journal: Am J Physiol Endocrinol Metab
Title: Stimulation of Gs signaling in MC4R cells by DREADD increases energy expenditure, suppresses food intake, and increases locomotor activity in mice.
Volume: 322
Issue: 5
Pages: E436-E445
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Publication
32916307 | J:305517
 
First Author: Rojo D
Year: 2020
Journal: Mol Metab
Title: Mouse models for V103I and I251L gain of function variants of the human MC4R display decreased adiposity but are not protected against a hypercaloric diet.
Volume: 42
Pages: 101077
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Publication
33053350 | J:300072
First Author: Bruschetta G
Year: 2020
Journal: Cell Rep
Title: MC4R Signaling in Dorsal Raphe Nucleus Controls Feeding, Anxiety, and Depression.
Volume: 33
Issue: 2
Pages: 108267
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Publication
22492873 | J:312615
First Author: Hatoum IJ
Year: 2012
Journal: J Clin Endocrinol Metab
Title: Melanocortin-4 receptor signaling is required for weight loss after gastric bypass surgery.
Volume: 97
Issue: 6
Pages: E1023-31
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Publication
26500841 | J:251772
First Author: Obici S
Year: 2015
Journal: Mol Metab
Title: Moderate voluntary exercise attenuates the metabolic syndrome in melanocortin-4 receptor-deficient rats showing central dopaminergic dysregulation.
Volume: 4
Issue: 10
Pages: 692-705
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Publication
25096581 | J:306585
First Author: Li XF
Year: 2014
Journal: J Biol Chem
Title: An essential role for the K+-dependent Na+/Ca2+-exchanger, NCKX4, in melanocortin-4-receptor-dependent satiety.
Volume: 289
Issue: 37
Pages: 25445-59
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Publication
24315371 | J:206137
First Author: Xu Y
Year: 2013
Journal: Cell Metab
Title: Glutamate mediates the function of melanocortin receptor 4 on Sim1 neurons in body weight regulation.
Volume: 18
Issue: 6
Pages: 860-70
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Publication
28829041 | J:256681
   
First Author: Litt MJ
Year: 2017
Journal: Elife
Title: Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy.
Volume: 6
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Publication
30130530 | J:267671
First Author: Zhang M
Year: 2018
Journal: Dev Cell
Title: Melanocortin Receptor 4 Signaling Regulates Vertebrate Limb Regeneration.
Volume: 46
Issue: 4
Pages: 397-409.e5
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Publication
23786641 | J:213389
First Author: Cui H
Year: 2013
Journal: Genes Brain Behav
Title: The expression of MC4Rs in D1R neurons regulates food intake and locomotor sensitization to cocaine.
Volume: 12
Issue: 6
Pages: 658-65
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Publication
37033219 | J:345404
 
First Author: Semple EA
Year: 2023
Journal: Front Endocrinol (Lausanne)
Title: Melanocortin 4 receptor signaling in Sim1 neurons permits sexual receptivity in female mice.
Volume: 14
Pages: 983670
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Publication
17194736 | J:129583
First Author: Voss-Andreae A
Year: 2007
Journal: Endocrinology
Title: Role of the central melanocortin circuitry in adaptive thermogenesis of brown adipose tissue.
Volume: 148
Issue: 4
Pages: 1550-60
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Publication
27829153 | J:242331
First Author: Shen Y
Year: 2016
Journal: Cell Rep
Title: Stimulation of the Hippocampal POMC/MC4R Circuit Alleviates Synaptic Plasticity Impairment in an Alzheimer's Disease Model.
Volume: 17
Issue: 7
Pages: 1819-1831
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Publication
29059347 | J:256399
First Author: Semple E
Year: 2018
Journal: Endocrinology
Title: Sim1 Neurons Are Sufficient for MC4R-Mediated Sexual Function in Male Mice.
Volume: 159
Issue: 1
Pages: 439-449
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Publication
22342812 | J:227615
First Author: Cui H
Year: 2012
Journal: Physiol Behav
Title: Melanocortin 4 receptor signaling in dopamine 1 receptor neurons is required for procedural memory learning.
Volume: 106
Issue: 2
Pages: 201-10
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Publication
33937937 | J:321737
First Author: Xu H
Year: 2021
Journal: Cell Regen
Title: Activation of the Melanocortin-4 receptor signaling by α-MSH stimulates nerve-dependent mouse digit regeneration.
Volume: 10
Issue: 1
Pages: 19
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Publication
27791019 | J:238802
First Author: Samuelsson AS
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Central role for melanocortin-4 receptors in offspring hypertension arising from maternal obesity.
Volume: 113
Issue: 43
Pages: 12298-12303
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Publication
22479599 | J:187121
First Author: Karlsson-Lindahl L
Year: 2012
Journal: PLoS One
Title: Heparanase affects food intake and regulates energy balance in mice.
Volume: 7
Issue: 3
Pages: e34313
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Publication
30445039 | J:268003
First Author: Brandt C
Year: 2018
Journal: Cell
Title: Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation.
Volume: 175
Issue: 5
Pages: 1321-1335.e20
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Publication
21544212 | J:172374
First Author: Pillot B
Year: 2011
Journal: PLoS One
Title: Role of hypothalamic melanocortin system in adaptation of food intake to food protein increase in mice.
Volume: 6
Issue: 4
Pages: e19107
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Publication
30140740 | J:287574
First Author: Ghamari-Langroudi M
Year: 2018
Journal: Sci Adv
Title: Regulation of energy rheostasis by the melanocortin-3 receptor.
Volume: 4
Issue: 8
Pages: eaat0866
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Publication
36692018 | J:336317
 
First Author: Bernard A
Year: 2023
Journal: JCI Insight
Title: MRAP2 regulates energy homeostasis by promoting primary cilia localization of MC4R.
Volume: 8
Issue: 2
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Publication
33824339 | J:329472
First Author: Olson B
Year: 2021
Journal: Nat Commun
Title: Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia.
Volume: 12
Issue: 1
Pages: 2057
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Publication
- | J:274751
     
First Author: Zhang Z
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Big_mac.
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Publication
- | J:265170
     
First Author: Zhang Z
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Cetacean.
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Publication
- | J:274968
     
First Author: Zhang Z
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for blubbery.
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Publication
35710868 | J:326861
First Author: Morita S
Year: 2022
Journal: Sci Rep
Title: Daisaikoto improves fatty liver and obesity in melanocortin-4 receptor gene-deficient mice via the activation of brown adipose tissue.
Volume: 12
Issue: 1
Pages: 10105
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Publication
29454748 | J:261462
First Author: Chiyonobu N
Year: 2018
Journal: Am J Pathol
Title: Fatty Acid Binding Protein 4 (FABP4) Overexpression in Intratumoral Hepatic Stellate Cells within Hepatocellular Carcinoma with Metabolic Risk Factors.
Volume: 188
Issue: 5
Pages: 1213-1224
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Publication
25065745 | J:220129
First Author: Xu Y
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Profound and rapid reduction in body temperature induced by the melanocortin receptor agonists.
Volume: 451
Issue: 2
Pages: 184-9
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Publication
37725372 | J:340726
 
First Author: Itoh M
Year: 2023
Journal: J Exp Med
Title: Lysosomal cholesterol overload in macrophages promotes liver fibrosis in a mouse model of NASH.
Volume: 220
Issue: 11
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Publication
34029949 | J:314691
 
First Author: Yoshioka N
Year: 2021
Journal: Biomed Pharmacother
Title: The sodium-glucose cotransporter-2 inhibitor Tofogliflozin prevents the progression of nonalcoholic steatohepatitis-associated liver tumors in a novel murine model.
Volume: 140
Pages: 111738
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Publication
24349208 | J:209729
First Author: Itoh M
Year: 2013
Journal: PLoS One
Title: Hepatic crown-like structure: a unique histological feature in non-alcoholic steatohepatitis in mice and humans.
Volume: 8
Issue: 12
Pages: e82163
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Publication
29402900 | J:263155
First Author: Shiba K
Year: 2018
Journal: Sci Rep
Title: Canagliflozin, an SGLT2 inhibitor, attenuates the development of hepatocellular carcinoma in a mouse model of human NASH.
Volume: 8
Issue: 1
Pages: 2362
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Publication
29802399 | J:263070
First Author: Goto T
Year: 2018
Journal: Sci Rep
Title: Obeticholic acid protects against hepatocyte death and liver fibrosis in a murine model of nonalcoholic steatohepatitis.
Volume: 8
Issue: 1
Pages: 8157
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Publication
21906580 | J:177386
First Author: Itoh M
Year: 2011
Journal: Am J Pathol
Title: Melanocortin 4 receptor-deficient mice as a novel mouse model of nonalcoholic steatohepatitis.
Volume: 179
Issue: 5
Pages: 2454-63
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Publication
38452767 | J:346742
     
First Author: Oya M
Year: 2024
Journal: Cell Metab
Title: Age-related ciliopathy: Obesogenic shortening of melanocortin-4 receptor-bearing neuronal primary cilia.
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Publication
33521599 | J:309299
First Author: Kanamori Y
Year: 2021
Journal: iScience
Title: Iron-rich Kupffer cells exhibit phenotypic changes during the development of liver fibrosis in NASH.
Volume: 24
Issue: 2
Pages: 102032
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Publication
20060958 | J:283968
First Author: Chuang JC
Year: 2010
Journal: Biol Psychiatry
Title: A beta3-adrenergic-leptin-melanocortin circuit regulates behavioral and metabolic changes induced by chronic stress.
Volume: 67
Issue: 11
Pages: 1075-82
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Publication
25816330 | J:229262
First Author: Konuma K
Year: 2015
Journal: PLoS One
Title: Eicosapentaenoic acid ameliorates non-alcoholic steatohepatitis in a novel mouse model using melanocortin 4 receptor-deficient mice.
Volume: 10
Issue: 3
Pages: e0121528
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Publication
31116984 | J:281004
First Author: Holland J
Year: 2019
Journal: Cell Rep
Title: A Brain-Melanocortin-Vagus Axis Mediates Adipose Tissue Expansion Independently of Energy Intake.
Volume: 27
Issue: 8
Pages: 2399-2410.e6
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Publication
25730108 | J:222118
First Author: Arble DM
Year: 2015
Journal: Endocrinology
Title: The melanocortin-4 receptor integrates circadian light cues and metabolism.
Volume: 156
Issue: 5
Pages: 1685-91
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Publication
21169216 | J:169023
First Author: Ghamari-Langroudi M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Multinodal regulation of the arcuate/paraventricular nucleus circuit by leptin.
Volume: 108
Issue: 1
Pages: 355-60
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Publication
23869016 | J:199365
First Author: Asai M
Year: 2013
Journal: Science
Title: Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity.
Volume: 341
Issue: 6143
Pages: 275-8
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Publication
26829592 | J:230718
   
First Author: Chaly AL
Year: 2016
Journal: Elife
Title: The Melanocortin Receptor Accessory Protein 2 promotes food intake through inhibition of the Prokineticin Receptor-1.
Volume: 5
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Publication
16269339 | J:115192
First Author: Balthasar N
Year: 2005
Journal: Cell
Title: Divergence of melanocortin pathways in the control of food intake and energy expenditure.
Volume: 123
Issue: 3
Pages: 493-505
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Publication
23374353 | J:193452
First Author: Sohn JW
Year: 2013
Journal: Cell
Title: Melanocortin 4 receptors reciprocally regulate sympathetic and parasympathetic preganglionic neurons.
Volume: 152
Issue: 3
Pages: 612-9
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Publication
21284986 | J:169562
First Author: Rossi J
Year: 2011
Journal: Cell Metab
Title: Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis.
Volume: 13
Issue: 2
Pages: 195-204
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Publication
37078546 | J:344105
First Author: Liu H
Year: 2023
Journal: FASEB J
Title: Glutamatergic melanocortin-4 receptor neurons regulate body weight.
Volume: 37
Issue: 5
Pages: e22920
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Publication
31969650 | J:292923
First Author: Kawakubo M
Year: 2020
Journal: Sci Rep
Title: Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis-associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects.
Volume: 10
Issue: 1
Pages: 983
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Publication
- | J:218963
     
First Author: SoRelle J
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for chubby
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Publication
31862949 | J:287488
First Author: Asakawa M
Year: 2019
Journal: Sci Rep
Title: Upregulation of cancer-associated gene expression in activated fibroblasts in a mouse model of non-alcoholic steatohepatitis.
Volume: 9
Issue: 1
Pages: 19601
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Publication
32768187 | J:306073
First Author: Yoshida T
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Blocking sphingosine 1-phosphate receptor 2 accelerates hepatocellular carcinoma progression in a mouse model of NASH.
Volume: 530
Issue: 4
Pages: 665-672
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Publication
31009611 | J:283569
 
First Author: Lima LB
Year: 2019
Journal: Brain Res
Title: Relationship of α-MSH and AgRP axons to the perikarya of melanocortin-4 receptor neurons.
Volume: 1717
Pages: 136-146
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Publication
23842677 | J:201516
First Author: do Carmo JM
Year: 2013
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Differential control of metabolic and cardiovascular functions by melanocortin-4 receptors in proopiomelanocortin neurons.
Volume: 305
Issue: 4
Pages: R359-68
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Publication
31794265 | J:286281
First Author: Framnes-DeBoer SN
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