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Search results 1 to 100 out of 198 for Mcm4

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Saccharomyces cerevisiae
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Shima N
Year: 2007
Journal: Nat Genet
Title: A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice.
Volume: 39
Issue: 1
Pages: 93-8
Publication
First Author: Hughes CR
Year: 2012
Journal: J Clin Invest
Title: MCM4 mutation causes adrenal failure, short stature, and natural killer cell deficiency in humans.
Volume: 122
Issue: 3
Pages: 814-20
GXD Expression  
Probe: MGI:6400986
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-23
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3116917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6400990
Age: embryonic day 10.5
Image: 7d MCM4 -/-
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6400986
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6400990
Age: embryonic day 10.5
Image: 7d MCM4 +/+
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6400986
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6400989
Age: embryonic day 10.5
Image: 7b MCM4 +/+
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6400986
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-23
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3747517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6400989
Age: embryonic day 10.5
Image: 7b MCM4 -/-
Detected: true
Specimen Num: 2
Publication
First Author: Gineau L
Year: 2012
Journal: J Clin Invest
Title: Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency.
Volume: 122
Issue: 3
Pages: 821-32
Publication
First Author: Bagley BN
Year: 2012
Journal: PLoS Genet
Title: A dominantly acting murine allele of Mcm4 causes chromosomal abnormalities and promotes tumorigenesis.
Volume: 8
Issue: 11
Pages: e1003034
Publication
First Author: You Z
Year: 2002
Journal: J Biol Chem
Title: Roles of Mcm7 and Mcm4 subunits in the DNA helicase activity of the mouse Mcm4/6/7 complex.
Volume: 277
Issue: 45
Pages: 42471-9
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Kimura H
Year: 1995
Journal: Nucleic Acids Res
Title: Molecular cloning of cDNA encoding mouse Cdc21 and CDC46 homologs and characterization of the products: physical interaction between P1(MCM3) and CDC46 proteins.
Volume: 23
Issue: 12
Pages: 2097-104
Publication
First Author: Chuang CH
Year: 2012
Journal: Nucleic Acids Res
Title: Post-transcriptional homeostasis and regulation of MCM2-7 in mammalian cells.
Volume: 40
Issue: 11
Pages: 4914-24
Publication
First Author: Ishimi Y
Year: 2001
Journal: J Biol Chem
Title: Biochemical activities associated with mouse Mcm2 protein.
Volume: 276
Issue: 46
Pages: 42744-52
Publication
First Author: You Z
Year: 1999
Journal: Mol Cell Biol
Title: Biochemical analysis of the intrinsic Mcm4-Mcm6-mcm7 DNA helicase activity.
Volume: 19
Issue: 12
Pages: 8003-15
Publication
First Author: Chu CC
Year: 1998
Journal: Mol Immunol
Title: Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis.
Volume: 35
Issue: 8
Pages: 487-502
Publication
First Author: Chuang CH
Year: 2010
Journal: PLoS Genet
Title: Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress.
Volume: 6
Issue: 9
Pages: e1001110
Publication
First Author: Wallace MD
Year: 2014
Journal: Oncogene
Title: Role of DNA damage response pathways in preventing carcinogenesis caused by intrinsic replication stress.
Volume: 33
Issue: 28
Pages: 3688-95
Publication
First Author: Kawabata T
Year: 2011
Journal: Mamm Genome
Title: A reduction of licensed origins reveals strain-specific replication dynamics in mice.
Volume: 22
Issue: 9-10
Pages: 506-17
Publication
First Author: McNairn AJ
Year: 2019
Journal: Nature
Title: Female-biased embryonic death from inflammation induced by genomic instability.
Volume: 567
Issue: 7746
Pages: 105-108
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression  
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4848339
Age: embryonic day 10.5
Note: Staining is present in the metencephalon.
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4848339
Age: embryonic day 11.5
Note: Staining is present in the metencephalon.
Detected: true
Specimen Num: 3
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690968
Age: postnatal adult
Image: JAX_1371460
Note: kidney
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1614815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4848339
Age: embryonic day 9.5
Note: Staining is present in the metencephalon.
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1640515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4848339
Age: embryonic day 9.5
Note: There is strong staining in the anterior and posterior limb.
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1640517
Pattern: Non-Uniform
Stage: TS17
Assay Id: MGI:4848339
Age: embryonic day 10.5
Note: Staining is strong in the posterior limb and moderate in the anterior limb.
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1640519
Pattern: Non-Uniform
Stage: TS19
Assay Id: MGI:4848339
Age: embryonic day 11.5
Note: Staining is strong in the antero-distal and posterior-distal regions and moderate in the antero-proximal and posterior-proximal regions of the limb.
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4848339
Age: embryonic day 10.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4848339
Age: embryonic day 11.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4848339
Age: embryonic day 9.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1399168
Assay Type: RNA in situ
Annotation Date: 2011-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5287170
Age: embryonic day 14.5
Image: 5c
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3270515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4848339
Age: embryonic day 9.5
Note: There is strong staining in the distal and proximal limb.
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3270517
Pattern: Non-Uniform
Stage: TS17
Assay Id: MGI:4848339
Age: embryonic day 10.5
Note: Staining is strong in the progress zone and moderate in the middle and proximal limb.
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3270519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4848339
Age: embryonic day 11.5
Note: Staining is present in the progress zone and middle limb.
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4848339
Age: embryonic day 9.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4848339
Age: embryonic day 10.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691019
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4848339
Age: embryonic day 11.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689615
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4848339
Age: embryonic day 9.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4844362
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4848339
Age: embryonic day 10.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1399168
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Pattern: Ubiquitous
Stage: TS23
Assay Id: MGI:4826130
Age: embryonic day 14.5
Image: euxassay_013775_10
Detected: true
Specimen Num: 1
Publication
First Author: Wallace MD
Year: 2012
Journal: Genetics
Title: Comparative oncogenomics implicates the neurofibromin 1 gene (NF1) as a breast cancer driver.
Volume: 192
Issue: 2
Pages: 385-96
Publication
First Author: Chandramouli A
Year: 2007
Journal: Carcinogenesis
Title: Haploinsufficiency of the cdc2l gene contributes to skin cancer development in mice.
Volume: 28
Issue: 9
Pages: 2028-35
Publication
First Author: Sallés FJ
Year: 1992
Journal: Genes Dev
Title: Isolation of novel murine maternal mRNAs regulated by cytoplasmic polyadenylation.
Volume: 6
Issue: 7
Pages: 1202-12
Publication
First Author: Kimura H
Year: 1996
Journal: Genes Cells
Title: Mouse MCM proteins: complex formation and transportation to the nucleus.
Volume: 1
Issue: 11
Pages: 977-93
Publication
First Author: You Z
Year: 2005
Journal: Nucleic Acids Res
Title: DNA binding and helicase actions of mouse MCM4/6/7 helicase.
Volume: 33
Issue: 9
Pages: 3033-47
Publication
First Author: Hartford SA
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Minichromosome maintenance helicase paralog MCM9 is dispensible for DNA replication but functions in germ-line stem cells and tumor suppression.
Volume: 108
Issue: 43
Pages: 17702-7
Publication
First Author: Schaefer S
Year: 2019
Journal: Sci Rep
Title: Down-regulation of CK2α correlates with decreased expression levels of DNA replication minichromosome maintenance protein complex (MCM) genes.
Volume: 9
Issue: 1
Pages: 14581
Publication
First Author: Bonner AE
Year: 2003
Journal: J Med Genet
Title: Gene expression signatures identify novel regulatory pathways during murine lung development: implications for lung tumorigenesis.
Volume: 40
Issue: 6
Pages: 408-17
Publication
First Author: You Z
Year: 2008
Journal: J Biol Chem
Title: Cdt1 forms a complex with the minichromosome maintenance protein (MCM) and activates its helicase activity.
Volume: 283
Issue: 36
Pages: 24469-77
Publication
First Author: Saito T
Year: 1998
Journal: Mamm Genome
Title: Mouse cdc21 only 0.5 kb upstream from dna-pkcs in a head-to-head organization: an implication of co-evolution of ATM family members and cell cycle regulating genes.
Volume: 9
Issue: 9
Pages: 769-72
Publication
First Author: O'Driscoll M
Year: 2017
Journal: J Pathol
Title: The pathological consequences of impaired genome integrity in humans; disorders of the DNA replication machinery.
Volume: 241
Issue: 2
Pages: 192-207
Publication
First Author: Kartha N
Year: 2016
Journal: Genetics
Title: The Chromatin Remodeling Component Arid1a Is a Suppressor of Spontaneous Mammary Tumors in Mice.
Volume: 203
Issue: 4
Pages: 1601-11
Publication
First Author: Kuipers MA
Year: 2011
Journal: J Cell Biol
Title: Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload.
Volume: 192
Issue: 1
Pages: 29-41
Publication
First Author: Abramova N
Year: 2005
Journal: Dev Biol
Title: Stage-specific changes in gene expression in acutely isolated mouse CNS progenitor cells.
Volume: 283
Issue: 2
Pages: 269-81
Publication
First Author: Ouseph MM
Year: 2012
Journal: Dev Cell
Title: Atypical E2F repressors and activators coordinate placental development.
Volume: 22
Issue: 4
Pages: 849-62
Publication
First Author: Pihlajoki M
Year: 2013
Journal: Endocrinology
Title: Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice.
Volume: 154
Issue: 5
Pages: 1754-67
Publication
First Author: Machold R
Year: 2011
Journal: Gene Expr Patterns
Title: Genes expressed in Atoh1 neuronal lineages arising from the r1/isthmus rhombic lip.
Volume: 11
Issue: 5-6
Pages: 349-59
Publication
First Author: Koss M
Year: 2012
Journal: Dev Cell
Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Volume: 22
Issue: 5
Pages: 913-26
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff