Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
Homo sapiens |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Drosophila melanogaster |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Rattus norvegicus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Saccharomyces cerevisiae |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Danio rerio |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
In eukaryotes, Mcm6 is a component of the MCM2-7 complex (MCM complex), which consists of six sequence-related AAA + type ATPases/helicases that form a hetero-hexameric ring []. MCM2-7 complex is part of the pre-replication complex (pre-RC). In G1 phase, inactive MCM2-7 complex is loaded onto origins of DNA replication [, , ]. During G1-S phase, MCM2-7 complex is activated to unwind the double stranded DNA and plays an important role in DNA replication forks elongation [].The components of the MCM2-7complex are: DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, DNA replication licensing factor MCM5, DNA replication licensing factor MCM6, DNA replication licensing factor MCM7, |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus |
Length: |
821
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus |
Length: |
821
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus |
Length: |
794
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus |
Length: |
821
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Remus D |
Year: |
2009 |
Journal: |
Cell |
Title: |
Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing. |
Volume: |
139 |
Issue: |
4 |
Pages: |
719-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Symeonidou IE |
Year: |
2012 |
Journal: |
FEBS Lett |
Title: |
Control over DNA replication in time and space. |
Volume: |
586 |
Issue: |
18 |
Pages: |
2803-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Evrin C |
Year: |
2009 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication. |
Volume: |
106 |
Issue: |
48 |
Pages: |
20240-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Singleton MR |
Year: |
2007 |
Journal: |
Annu Rev Biochem |
Title: |
Structure and mechanism of helicases and nucleic acid translocases. |
Volume: |
76 |
|
Pages: |
23-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kimura H |
Year: |
1996 |
Journal: |
Genes Cells |
Title: |
Mouse MCM proteins: complex formation and transportation to the nucleus. |
Volume: |
1 |
Issue: |
11 |
Pages: |
977-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yanagi K |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity. |
Volume: |
277 |
Issue: |
43 |
Pages: |
40871-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
You Z |
Year: |
1999 |
Journal: |
Mol Cell Biol |
Title: |
Biochemical analysis of the intrinsic Mcm4-Mcm6-mcm7 DNA helicase activity. |
Volume: |
19 |
Issue: |
12 |
Pages: |
8003-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
You Z |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Roles of Mcm7 and Mcm4 subunits in the DNA helicase activity of the mouse Mcm4/6/7 complex. |
Volume: |
277 |
Issue: |
45 |
Pages: |
42471-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barton KM |
Year: |
2008 |
Journal: |
Dev Dyn |
Title: |
Expression patterns and cell cycle profiles of PCNA, MCM6, cyclin D1, cyclin A2, cyclin B1, and phosphorylated histone H3 in the developing mouse retina. |
Volume: |
237 |
Issue: |
3 |
Pages: |
672-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pacal M |
Year: |
2012 |
Journal: |
Dev Dyn |
Title: |
Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. |
Volume: |
241 |
Issue: |
10 |
Pages: |
1525-44 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1331753 |
Assay Type: |
RT-PCR |
Annotation Date: |
1999-03-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603911 |
|
Stage: |
TS11 |
Assay Id: |
MGI:1331754 |
Age: |
embryonic day 7.5 |
|
|
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1331753 |
Assay Type: |
RT-PCR |
Annotation Date: |
1999-03-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603911 |
|
Stage: |
TS11 |
Assay Id: |
MGI:1331754 |
Age: |
embryonic day 7.5 |
|
|
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1331753 |
Assay Type: |
RT-PCR |
Annotation Date: |
1999-03-18 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603911 |
|
Stage: |
TS11 |
Assay Id: |
MGI:1331754 |
Age: |
embryonic day 7.5 |
|
|
Detected: |
false |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1331753 |
Assay Type: |
RT-PCR |
Annotation Date: |
1999-03-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1604211 |
|
Stage: |
TS11 |
Assay Id: |
MGI:1331754 |
Age: |
embryonic day 7.5 |
|
|
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1331753 |
Assay Type: |
RT-PCR |
Annotation Date: |
1999-03-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1604211 |
|
Stage: |
TS11 |
Assay Id: |
MGI:1331754 |
Age: |
embryonic day 7.5 |
|
|
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1331753 |
Assay Type: |
RT-PCR |
Annotation Date: |
1999-03-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1604211 |
|
Stage: |
TS11 |
Assay Id: |
MGI:1331754 |
Age: |
embryonic day 7.5 |
|
|
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691617 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 10.5 |
|
Note: |
Staining is present in the metencephalon. |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691619 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 11.5 |
|
Note: |
Staining is present in the metencephalon. |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619819 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:3784865 |
Age: |
embryonic day 11.5 |
Image: |
1A,C |
Note: |
Expression is in embryonic vasculature in and near the eye and in the extraocular tissues. |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619821 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:3784865 |
Age: |
embryonic day 13.5 |
Image: |
1D,F |
Note: |
Expression is in embryonic vasculature in and near the eye and in the extraocular tissues. |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619821 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3784865 |
Age: |
embryonic day 13.5 |
Image: |
4A,C |
|
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1614815 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 9.5 |
|
Note: |
Staining is present in the metencephalon. |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640515 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 9.5 |
|
Note: |
There is strong staining in the anterior and posterior limb. |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640517 |
Pattern: |
Non-Uniform |
Stage: |
TS17 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 10.5 |
|
Note: |
Staining is strong in the posterior limb and moderate in the anterior limb. |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640519 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 11.5 |
|
Note: |
Staining is present in the antero-distal and posterior-distal regions of the limb. |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1717219 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:3784865 |
Age: |
embryonic day 11.5 |
Image: |
1A,C |
|
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1717221 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3784865 |
Age: |
embryonic day 13.5 |
Image: |
1D,F |
|
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1697417 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 10.5 |
|
|
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1697419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 11.5 |
|
|
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1738219 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 11.5 |
|
Note: |
Staining is present in the external genitalia. |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1716821 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3784865 |
Age: |
embryonic day 13.5 |
Image: |
1D,F |
|
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1716821 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:3784865 |
Age: |
embryonic day 13.5 |
Image: |
4A,C |
Note: |
Weak expression in the inner retina. |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1915528 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3784865 |
Age: |
postnatal day 6 |
Image: |
1M,O |
Note: |
Expression is in a narrow band of cells in the developing inner nuclear layer. |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1614015 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 9.5 |
|
|
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1716319 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:3784865 |
Age: |
embryonic day 11.5 |
Image: |
1A,C |
|
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3270515 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 9.5 |
|
Note: |
There is strong staining in the distal and proximal limb. |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3270517 |
Pattern: |
Non-Uniform |
Stage: |
TS17 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 10.5 |
|
Note: |
Staining is strong in the progress zone and moderate in the middle and proximal limb. |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3270519 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 11.5 |
|
Note: |
Staining is present in the progress zone and middle limb. |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691015 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 9.5 |
|
|
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691017 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 10.5 |
|
|
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691019 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 11.5 |
|
|
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689615 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 9.5 |
|
|
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689617 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 10.5 |
|
|
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274319 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:3784865 |
Age: |
embryonic day 11.5 |
Image: |
1A,C |
Note: |
Expression is in embryonic vasculature in and near the eye and in the extraocular tissues. |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274321 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:3784865 |
Age: |
embryonic day 13.5 |
Image: |
1D,F |
Note: |
Expression is in embryonic vasculature in and near the eye and in the extraocular tissues. |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1667415 |
Pattern: |
Regionally restricted |
Stage: |
TS15 |
Assay Id: |
MGI:3784865 |
Age: |
embryonic day 9.5 |
|
Note: |
Expression is in most cells of the retina and surrounding tissues. |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3185819 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:3784865 |
Age: |
embryonic day 11.5 |
Image: |
1A,C |
Note: |
Expression is in embryonic vasculature in and near the eye and in the extraocular tissues. |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3185821 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:3784865 |
Age: |
embryonic day 13.5 |
Image: |
1D,F |
Note: |
Expression is in embryonic vasculature in and near the eye and in the extraocular tissues. |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4844648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-12-22 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1636717 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:4848537 |
Age: |
embryonic day 10.5 |
|
Note: |
Staining is present in the external genitalia. |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1859224 |
Pattern: |
Regionally restricted |
Stage: |
TS24 |
Assay Id: |
MGI:3784865 |
Age: |
embryonic day 16.5 |
Image: |
1G,I |
Note: |
Expression is in the neuroblast layer and excluded from cells located in the developing ganglion cell layer and inner boundary of the neuroblastic layer. |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3568627 |
Pattern: |
Single cells |
Stage: |
TS27 |
Assay Id: |
MGI:3784865 |
Age: |
postnatal day 0 |
Image: |
4J,L |
|
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3574227 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:3784865 |
Age: |
postnatal day 3 |
Image: |
1J,L |
Note: |
Expression is in the neuroblast layer and excluded from cells located in the developing ganglion cell layer and inner boundary of the neuroblastic layer. |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3574228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3784865 |
Age: |
postnatal day 15 |
Image: |
1P,R |
|
Detected: |
false |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3574227 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:3784865 |
Age: |
postnatal day 0 |
Image: |
4D,F |
Note: |
Expression is in the neuroblast layer in newly postmitotic cells. |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3574227 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:3784865 |
Age: |
postnatal day 0 |
Image: |
4G,I |
Note: |
Expression is in the neuroblast layer in newly postmitotic cells. |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3574227 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:3784865 |
Age: |
postnatal day 0 |
Image: |
4J,L |
Note: |
Expression is in the neuroblast layer in newly postmitotic cells. |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3574227 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:3784865 |
Age: |
postnatal day 0 |
Image: |
4M,O |
Note: |
Expression is in the neuroblast layer in newly postmitotic cells. |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3574227 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:3784865 |
Age: |
postnatal day 0 |
Image: |
7A,C |
Note: |
Expression is in the neuroblast layer. |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3574227 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:3784865 |
Age: |
postnatal day 0 |
Image: |
7D,F |
Note: |
Expression is in the neuroblast layer. |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3574227 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:3784865 |
Age: |
postnatal day 0 |
Image: |
7G,I |
Note: |
Expression is in the neuroblast layer. |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3574227 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:3784865 |
Age: |
postnatal day 0 |
Image: |
7J,L |
Note: |
Expression is in the neuroblast layer. |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3784850 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3574227 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:3784865 |
Age: |
postnatal day 0 |
Image: |
7M,O |
Note: |
Expression is in the neuroblast layer. |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5811612 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-12-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754721 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5811629 |
Age: |
embryonic day 13.5 |
Image: |
S4F |
Note: |
Significant overlap is observed with Mki67. |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee C |
Year: |
2004 |
Journal: |
Nature |
Title: |
Structural basis for inhibition of the replication licensing factor Cdt1 by geminin. |
Volume: |
430 |
Issue: |
7002 |
Pages: |
913-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
You Z |
Year: |
2005 |
Journal: |
Nucleic Acids Res |
Title: |
DNA binding and helicase actions of mouse MCM4/6/7 helicase. |
Volume: |
33 |
Issue: |
9 |
Pages: |
3033-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Swiech L |
Year: |
2007 |
Journal: |
Int J Dev Biol |
Title: |
Accumulation and dynamics of proteins of the MCM family during mouse oogenesis and the first embryonic cell cycle. |
Volume: |
51 |
Issue: |
4 |
Pages: |
283-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
You Z |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
Cdt1 forms a complex with the minichromosome maintenance protein (MCM) and activates its helicase activity. |
Volume: |
283 |
Issue: |
36 |
Pages: |
24469-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chuang CH |
Year: |
2010 |
Journal: |
PLoS Genet |
Title: |
Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress. |
Volume: |
6 |
Issue: |
9 |
Pages: |
e1001110 |
|
•
•
•
•
•
|
Publication |
First Author: |
Frank CL |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
Control of activating transcription factor 4 (ATF4) persistence by multisite phosphorylation impacts cell cycle progression and neurogenesis. |
Volume: |
285 |
Issue: |
43 |
Pages: |
33324-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kuipers MA |
Year: |
2011 |
Journal: |
J Cell Biol |
Title: |
Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload. |
Volume: |
192 |
Issue: |
1 |
Pages: |
29-41 |
|
•
•
•
•
•
|