| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
In eukaryotes, Mcm6 is a component of the MCM2-7 complex (MCM complex), which consists of six sequence-related AAA + type ATPases/helicases that form a hetero-hexameric ring []. MCM2-7 complex is part of the pre-replication complex (pre-RC). In G1 phase, inactive MCM2-7 complex is loaded onto origins of DNA replication [, , ]. During G1-S phase, MCM2-7 complex is activated to unwind the double stranded DNA and plays an important role in DNA replication forks elongation [].The components of the MCM2-7 complex are:DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, DNA replication licensing factor MCM5, DNA replication licensing factor MCM6, DNA replication licensing factor MCM7, |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
821
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
794
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
794
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
821
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
821
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Remus D |
| Year: |
2009 |
| Journal: |
Cell |
| Title: |
Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing. |
| Volume: |
139 |
| Issue: |
4 |
| Pages: |
719-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Symeonidou IE |
| Year: |
2012 |
| Journal: |
FEBS Lett |
| Title: |
Control over DNA replication in time and space. |
| Volume: |
586 |
| Issue: |
18 |
| Pages: |
2803-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Evrin C |
| Year: |
2009 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication. |
| Volume: |
106 |
| Issue: |
48 |
| Pages: |
20240-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Singleton MR |
| Year: |
2007 |
| Journal: |
Annu Rev Biochem |
| Title: |
Structure and mechanism of helicases and nucleic acid translocases. |
| Volume: |
76 |
|
| Pages: |
23-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yanagi K |
| Year: |
2005 |
| Journal: |
J Biol Chem |
| Title: |
Caenorhabditis elegans geminin homologue participates in cell cycle regulation and germ line development. |
| Volume: |
280 |
| Issue: |
20 |
| Pages: |
19689-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Izumi M |
| Year: |
2000 |
| Journal: |
Nucleic Acids Res |
| Title: |
The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase. |
| Volume: |
28 |
| Issue: |
23 |
| Pages: |
4769-77 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yanagi K |
| Year: |
2002 |
| Journal: |
J Biol Chem |
| Title: |
Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity. |
| Volume: |
277 |
| Issue: |
43 |
| Pages: |
40871-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
You Z |
| Year: |
2002 |
| Journal: |
J Biol Chem |
| Title: |
Roles of Mcm7 and Mcm4 subunits in the DNA helicase activity of the mouse Mcm4/6/7 complex. |
| Volume: |
277 |
| Issue: |
45 |
| Pages: |
42471-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Barton KM |
| Year: |
2008 |
| Journal: |
Dev Dyn |
| Title: |
Expression patterns and cell cycle profiles of PCNA, MCM6, cyclin D1, cyclin A2, cyclin B1, and phosphorylated histone H3 in the developing mouse retina. |
| Volume: |
237 |
| Issue: |
3 |
| Pages: |
672-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
You Z |
| Year: |
1999 |
| Journal: |
Mol Cell Biol |
| Title: |
Biochemical analysis of the intrinsic Mcm4-Mcm6-mcm7 DNA helicase activity. |
| Volume: |
19 |
| Issue: |
12 |
| Pages: |
8003-15 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Leturcq M |
| Year: |
2018 |
| Journal: |
Cell Mol Life Sci |
| Title: |
O-GlcNAc transferase associates with the MCM2-7 complex and its silencing destabilizes MCM-MCM interactions. |
| Volume: |
75 |
| Issue: |
23 |
| Pages: |
4321-4339 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pacal M |
| Year: |
2012 |
| Journal: |
Dev Dyn |
| Title: |
Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. |
| Volume: |
241 |
| Issue: |
10 |
| Pages: |
1525-44 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1331753 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
1999-03-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603911 |
|
| Stage: |
TS11 |
| Assay Id: |
MGI:1331754 |
| Age: |
embryonic day 7.5 |
|
|
| Specimen Label: |
1x |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1331753 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
1999-03-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603911 |
|
| Stage: |
TS11 |
| Assay Id: |
MGI:1331754 |
| Age: |
embryonic day 7.5 |
|
|
| Specimen Label: |
10x |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1331753 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
1999-03-18 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603911 |
|
| Stage: |
TS11 |
| Assay Id: |
MGI:1331754 |
| Age: |
embryonic day 7.5 |
|
|
| Specimen Label: |
100x |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1331753 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
1999-03-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1604211 |
|
| Stage: |
TS11 |
| Assay Id: |
MGI:1331754 |
| Age: |
embryonic day 7.5 |
|
|
| Specimen Label: |
1x |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1331753 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
1999-03-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1604211 |
|
| Stage: |
TS11 |
| Assay Id: |
MGI:1331754 |
| Age: |
embryonic day 7.5 |
|
|
| Specimen Label: |
10x |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1331753 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
1999-03-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1604211 |
|
| Stage: |
TS11 |
| Assay Id: |
MGI:1331754 |
| Age: |
embryonic day 7.5 |
|
|
| Specimen Label: |
100x |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8238021 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2025-08-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1604221 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:8238045 |
| Age: |
embryonic day 13.5 |
| Image: |
6 |
|
| Specimen Label: |
Wild-type |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8238021 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2025-08-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1604221 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:8238045 |
| Age: |
embryonic day 13.5 |
| Image: |
6 |
|
| Specimen Label: |
Rb-/- |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8238021 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2025-08-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1604219 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:8238050 |
| Age: |
embryonic day 11.5 |
| Image: |
6 |
|
| Specimen Label: |
Wild-type |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8238021 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2025-08-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1604219 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:8238050 |
| Age: |
embryonic day 11.5 |
| Image: |
6 |
|
| Specimen Label: |
E2f4-/- |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8238021 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2025-08-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1604219 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:8238050 |
| Age: |
embryonic day 11.5 |
| Image: |
6 |
|
| Specimen Label: |
Rb-/- |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8238021 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2025-08-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1604219 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:8238050 |
| Age: |
embryonic day 11.5 |
| Image: |
6 |
|
| Specimen Label: |
Rb-/-;E2f4-/- |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8314325 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2026-03-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754420 |
|
| Stage: |
TS20 |
| Assay Id: |
MGI:8314352 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
+/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8314325 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2026-03-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754420 |
|
| Stage: |
TS20 |
| Assay Id: |
MGI:8314352 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
-/- |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1691617 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 10.5 |
|
| Note: |
Staining is present in the metencephalon. |
| Specimen Label: |
Table S4 - E10.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1691619 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Staining is present in the metencephalon. |
| Specimen Label: |
Table S4 - E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3784850 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2008-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619819 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:3784865 |
| Age: |
embryonic day 11.5 |
| Image: |
1A,C |
| Note: |
Expression is in embryonic vasculature in and near the eye and in the extraocular tissues. |
| Specimen Label: |
1A,C |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3784850 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2008-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619821 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:3784865 |
| Age: |
embryonic day 13.5 |
| Image: |
1D,F |
| Note: |
Expression is in embryonic vasculature in and near the eye and in the extraocular tissues. |
| Specimen Label: |
1D,F |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3784850 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2008-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619821 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:3784865 |
| Age: |
embryonic day 13.5 |
| Image: |
4A,C |
|
| Specimen Label: |
4A,C |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1614815 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 9.5 |
|
| Note: |
Staining is present in the metencephalon. |
| Specimen Label: |
Table S4 - E9.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640515 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 9.5 |
|
| Note: |
There is strong staining in the anterior and posterior limb. |
| Specimen Label: |
Table S4 - E9.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640517 |
| Pattern: |
Non-Uniform |
| Stage: |
TS17 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 10.5 |
|
| Note: |
Staining is strong in the posterior limb and moderate in the anterior limb. |
| Specimen Label: |
Table S4 - E10.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640519 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Staining is present in the antero-distal and posterior-distal regions of the limb. |
| Specimen Label: |
Table S4 - E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3784850 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2008-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717219 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:3784865 |
| Age: |
embryonic day 11.5 |
| Image: |
1A,C |
|
| Specimen Label: |
1A,C |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3784850 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2008-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717221 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:3784865 |
| Age: |
embryonic day 13.5 |
| Image: |
1D,F |
|
| Specimen Label: |
1D,F |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1697417 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 10.5 |
|
|
| Specimen Label: |
Table S4 - E10.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1697419 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
Table S4 - E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1738219 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Staining is present in the external genitalia. |
| Specimen Label: |
Table S4 - E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3784850 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2008-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716821 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:3784865 |
| Age: |
embryonic day 13.5 |
| Image: |
1D,F |
|
| Specimen Label: |
1D,F |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3784850 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2008-05-13 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716821 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:3784865 |
| Age: |
embryonic day 13.5 |
| Image: |
4A,C |
| Note: |
Weak expression in the inner retina. |
| Specimen Label: |
4A,C |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8256877 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-10-28 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716827 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:8257032 |
| Age: |
postnatal day 0 |
| Image: |
7C |
|
| Specimen Label: |
7C |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8256877 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-10-28 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716827 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:8257032 |
| Age: |
postnatal day 0 |
| Image: |
7D |
|
| Specimen Label: |
7D |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8256877 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-10-28 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:8257032 |
| Age: |
postnatal day 10 |
| Image: |
8C |
|
| Specimen Label: |
8C |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8256877 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-10-28 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716828 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:8257032 |
| Age: |
postnatal day 10 |
| Image: |
8D |
| Note: |
Disorganized population of proliferating cells. |
| Specimen Label: |
8D |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8256877 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-10-28 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:8257032 |
| Age: |
postnatal day 28 |
| Image: |
9C |
|
| Specimen Label: |
9C |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8256877 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-10-28 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716828 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:8257032 |
| Age: |
postnatal day 28 |
| Image: |
9D |
| Note: |
Aberrantly proliferating cells interspersed with progenitors, differentiating neuronal cells, Muller glia, retinal ganglion cells, amacrine cells and photoreceptors. |
| Specimen Label: |
9D |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1614015 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 9.5 |
|
|
| Specimen Label: |
Table S4 - E9.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3784850 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2008-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716319 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:3784865 |
| Age: |
embryonic day 11.5 |
| Image: |
1A,C |
|
| Specimen Label: |
1A,C |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270515 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 9.5 |
|
| Note: |
There is strong staining in the distal and proximal limb. |
| Specimen Label: |
Table S4 - E9.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270517 |
| Pattern: |
Non-Uniform |
| Stage: |
TS17 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 10.5 |
|
| Note: |
Staining is strong in the progress zone and moderate in the middle and proximal limb. |
| Specimen Label: |
Table S4 - E10.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270519 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Staining is present in the progress zone and middle limb. |
| Specimen Label: |
Table S4 - E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1691015 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 9.5 |
|
|
| Specimen Label: |
Table S4 - E9.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1691017 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 10.5 |
|
|
| Specimen Label: |
Table S4 - E10.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1691019 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
Table S4 - E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689615 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 9.5 |
|
|
| Specimen Label: |
Table S4 - E9.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689617 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 10.5 |
|
|
| Specimen Label: |
Table S4 - E10.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3784850 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2008-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3274319 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:3784865 |
| Age: |
embryonic day 11.5 |
| Image: |
1A,C |
| Note: |
Expression is in embryonic vasculature in and near the eye and in the extraocular tissues. |
| Specimen Label: |
1A,C |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3784850 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2008-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3274321 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:3784865 |
| Age: |
embryonic day 13.5 |
| Image: |
1D,F |
| Note: |
Expression is in embryonic vasculature in and near the eye and in the extraocular tissues. |
| Specimen Label: |
1D,F |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3784850 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2008-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1667415 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:3784865 |
| Age: |
embryonic day 9.5 |
|
| Note: |
Expression is in most cells of the retina and surrounding tissues. |
| Specimen Label: |
Not shown |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3784850 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2008-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3185819 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:3784865 |
| Age: |
embryonic day 11.5 |
| Image: |
1A,C |
| Note: |
Expression is in embryonic vasculature in and near the eye and in the extraocular tissues. |
| Specimen Label: |
1A,C |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3784850 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2008-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3185821 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:3784865 |
| Age: |
embryonic day 13.5 |
| Image: |
1D,F |
| Note: |
Expression is in embryonic vasculature in and near the eye and in the extraocular tissues. |
| Specimen Label: |
1D,F |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844648 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1636717 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:4848537 |
| Age: |
embryonic day 10.5 |
|
| Note: |
Staining is present in the external genitalia. |
| Specimen Label: |
Table S4 - E10.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|