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Search results 1 to 100 out of 127 for Mcoln3

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Type Details Score
Gene
55283 | MCOLN3
Type: gene
Organism: human
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Gene
469371 | MCOLN3
Type: gene
Organism: chimpanzee
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Gene
514345 | MCOLN3
Type: gene
Organism: cattle
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Gene
429091 | MCOLN3
Type: gene
Organism: chicken
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Gene
710987 | MCOLN3
Type: gene
Organism: macaque, rhesus
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Gene
549558 | mcoln3
Type: gene
Organism: frog, western clawed
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Gene
308022 | Mcoln3
Type: gene
Organism: rat
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Gene
490185 | MCOLN3
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1890500 | Mcoln3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
12403827 | J:80336
First Author: Di Palma F
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice.
Volume: 99
Issue: 23
Pages: 14994-9
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Publication
35031603 | J:320955
First Author: Spix B
Year: 2022
Journal: Nat Commun
Title: Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice.
Volume: 13
Issue: 1
Pages: 318
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Protein Coding Gene
MGP_CAROLIEiJ_G0025719 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0027967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0027926 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0027892 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0027938 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027668 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1890500 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028381 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027121 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027643 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0027783 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027750 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0027894 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027783 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028440 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0026844 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027201 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027170 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0026672 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
18048323 | J:128490
First Author: Grimm C
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: A helix-breaking mutation in TRPML3 leads to constitutive activity underlying deafness in the varitint-waddler mouse.
Volume: 104
Issue: 49
Pages: 19583-8
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Publication
18801844 | J:176565
First Author: van Aken AF
Year: 2008
Journal: J Physiol
Title: TRPML3 mutations cause impaired mechano-electrical transduction and depolarization by an inward-rectifier cation current in auditory hair cells of varitint-waddler mice.
Volume: 586
Issue: 22
Pages: 5403-18
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Publication
- | J:13133
First Author: Cloudman AM
Year: 1945
Journal: J Hered
Title: The varitint-waddler mouse. A dominant mutation in Mus musculus.
Volume: 36
Issue: 9
Pages: 258-263
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Publication
- | J:64107
 
First Author: Lane PW
Year: 1969
Journal: Mouse News Lett
Title: VaJ - varitint-waddler-Jackson
Volume: 41
Pages: 32
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Publication
5075894 | J:5297
First Author: Cools AR
Year: 1972
Journal: J Hered
Title: Asymmetrical spotting and direction of circling in the varitint-waddler mouse.
Volume: 63
Issue: 4
Pages: 167-71
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Publication
21344404 | J:187348
First Author: Castiglioni AJ
Year: 2011
Journal: J Comp Neurol
Title: Expression and vesicular localization of mouse Trpml3 in stria vascularis, hair cells, and vomeronasal and olfactory receptor neurons.
Volume: 519
Issue: 6
Pages: 1095-1114
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Publication
9745961 | J:49944
First Author: Cable J
Year: 1998
Journal: Hear Res
Title: Combined cochleo-saccular and neuroepithelial abnormalities in the Varitint-waddler-J (VaJ) mouse.
Volume: 123
Issue: 1-2
Pages: 125-36
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Publication
18162548 | J:131070
First Author: Nagata K
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The varitint-waddler (Va) deafness mutation in TRPML3 generates constitutive, inward rectifying currents and causes cell degeneration.
Volume: 105
Issue: 1
Pages: 353-8
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Publication
17962195 | J:128907
First Author: Kim HJ
Year: 2007
Journal: J Biol Chem
Title: Gain-of-function mutation in TRPML3 causes the mouse Varitint-Waddler phenotype.
Volume: 282
Issue: 50
Pages: 36138-42
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GXD Expression
GXD Expression
     
Probe: MGI:4822023
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759725
Stage: TS25
Assay Id: MGI:4822354
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4822023
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759726
Stage: TS26
Assay Id: MGI:4822354
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4822023
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:4822354
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:4822023
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:4822354
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:4822023
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4822354
Age: postnatal day 4
Specimen Label: P4
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:4822023
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4822354
Age: postnatal day 6
Specimen Label: P6
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:4822023
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4822354
Age: postnatal day 8
Specimen Label: P8
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_07
Specimen Label: euxassay_008566_07
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_08
Specimen Label: euxassay_008566_08
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_09
Specimen Label: euxassay_008566_09
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_10
Specimen Label: euxassay_008566_10
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_11
Specimen Label: euxassay_008566_11
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_14
Specimen Label: euxassay_008566_14
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_15
Specimen Label: euxassay_008566_15
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_16
Specimen Label: euxassay_008566_16
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_17
Specimen Label: euxassay_008566_17
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_18
Specimen Label: euxassay_008566_18
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_03
Specimen Label: euxassay_008566_03
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_04
Specimen Label: euxassay_008566_04
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_05
Specimen Label: euxassay_008566_05
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_06
Specimen Label: euxassay_008566_06
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_20
Specimen Label: euxassay_008566_20
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_21
Specimen Label: euxassay_008566_21
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:4422453
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4826134
Age: embryonic day 14.5
Image: euxassay_008566_22
Specimen Label: euxassay_008566_22
Detected: true
Specimen Num: 17
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Publication
- | J:77428
   
First Author: Falardeau JL
Year: 2002
Journal: GenBank Submission
Title: Mus musculus mucolipin-3 (Mcoln3) mRNA, complete cds
Pages: AF475086
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Publication
17989217 | J:127446
First Author: Xu H
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Activating mutation in a mucolipin transient receptor potential channel leads to melanocyte loss in varitint-waddler mice.
Volume: 104
Issue: 46
Pages: 18321-6
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Publication
21179200 | J:167711
First Author: Jörs S
Year: 2010
Journal: PLoS One
Title: Genetic inactivation of Trpml3 does not lead to hearing and vestibular impairment in mice.
Volume: 5
Issue: 12
Pages: e14317
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Publication
19299509 | J:149916
First Author: Grimm C
Year: 2009
Journal: J Biol Chem
Title: Life and death of sensory hair cells expressing constitutively active TRPML3.
Volume: 284
Issue: 20
Pages: 13823-31
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Publication
26027738 | J:223390
First Author: Miao Y
Year: 2015
Journal: Cell
Title: A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion.
Volume: 161
Issue: 6
Pages: 1306-19
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Publication
13654621 | J:233
First Author: CURRY GA
Year: 1959
Journal: J Embryol Exp Morphol
Title: Genetical and development studies on droopy-eared mice.
Volume: 7
Issue: 1
Pages: 39-65
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Publication
1262696 | J:5634
First Author: Marks SC Jr
Year: 1976
Journal: J Hered
Title: Osteopetrosis, a new recessive skeletal mutation on chromosome 12 of the mouse.
Volume: 67
Issue: 1
Pages: 11-18
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Publication
9746435 | J:49942
First Author: Steele EC Jr
Year: 1998
Journal: Curr Eye Res
Title: A mutation in the connexin 50 (Cx50) gene is a candidate for the No2 mouse cataract.
Volume: 17
Issue: 9
Pages: 883-9
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Publication
- | J:13518
 
First Author: Southard JL
Year: 1971
Journal: Mouse News Lett
Title: Soft coat and hemimelic extra toes.
Volume: 45
Pages: 29
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Publication
6203959 | J:7487
First Author: Mobraaten LE
Year: 1984
Journal: J Hered
Title: Location of histocompatibility and interferon loci on chromosome 3 of the mouse.
Volume: 75
Issue: 3
Pages: 233-4
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Publication
7026729 | J:6612
First Author: Holmes RS
Year: 1981
Journal: J Exp Zool
Title: Mouse alcohol dehydrogenase isozymes: products of closely localized duplicate genes exhibiting divergent kinetic properties.
Volume: 217
Issue: 2
Pages: 151-7
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Publication
- | J:4484
First Author: Holmes RS
Year: 1981
Journal: Dev Genet
Title: Genetic regulation of alcohol dehydrogenase C2 in the mouse. Developmental consequences of the temporal locus (Adh-3t) and positioning of Adh-3 on chromosome 3.
Volume: 2
Issue: 1
Pages: 89-98
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Publication
1021597 | J:5789
First Author: Taylor BA
Year: 1976
Journal: J Hered
Title: Linkage of the cadmium resistance locus to loci on mouse chromosome 12.
Volume: 67
Issue: 6
Pages: 389-90
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Publication
- | J:13871
 
First Author: Holmes RS
Year: 1981
Journal: Mouse News Lett
Title: Alcohol dehydrogenase C2 (stomach enzyme).
Volume: 64
Pages: 54
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Publication
- | J:13376
 
First Author: Bailey DW
Year: 1976
Journal: Jackson Lab Ann Rep
Title: Mapping new histocompatibility loci
Volume: 47
Pages: 73
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Publication
12209292 | J:78812
First Author: Kim HJ
Year: 2003
Journal: J Assoc Res Otolaryngol
Title: Genetic analyses of the mouse deafness mutations varitint-waddler (Va) and jerker (Espnje).
Volume: 4
Issue: 1
Pages: 83-90
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Publication
30479274 | J:277384
   
First Author: Plesch E
Year: 2018
Journal: Elife
Title: Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells.
Volume: 7
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Publication
18754773 | J:142459
First Author: Goswami C
Year: 2008
Journal: FEBS J
Title: Submembraneous microtubule cytoskeleton: biochemical and functional interplay of TRP channels with the cytoskeleton.
Volume: 275
Issue: 19
Pages: 4684-99
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Publication
- | J:13046
First Author: Deol MS
Year: 1954
Journal: J Genet
Title: The anomalies of the labyrinth of the mutants varitint-waddler, shaker-2 and jerker in the mouse.
Volume: 52
Issue: 3
Pages: 562-588
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Publication
29453205 | J:260847
First Author: Wiwatpanit T
Year: 2018
Journal: J Neurosci
Title: Codeficiency of Lysosomal Mucolipins 3 and 1 in Cochlear Hair Cells Diminishes Outer Hair Cell Longevity and Accelerates Age-Related Hearing Loss.
Volume: 38
Issue: 13
Pages: 3177-3189
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Publication
1401878 | J:1827
First Author: Lane PW
Year: 1992
Journal: J Hered
Title: Rostral cerebellar malformation, (rcm): a new recessive mutation on chromosome 3 of the mouse.
Volume: 83
Issue: 4
Pages: 315-8
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Publication
518534 | J:6249
First Author: Holmes RS
Year: 1979
Journal: Biochem Genet
Title: Genetics and ontogeny of alcohol dehydrogenase isozymes in the mouse: evidence for a cis-acting regulator gene (Adt-i) controlling C2 isozyme expression in reproductive tissues and close linkage of Adh-3 and Adt-i on chromosome 3.
Volume: 17
Issue: 5-6
Pages: 461-72
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First Author: Prochazka M
Year: 1985
Journal: Virology
Title: Interferon-induced guanylate-binding proteins: mapping of the murine Gbp-1 locus to chromosome 3.
Volume: 145
Issue: 2
Pages: 273-9
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6762206 | J:7000
First Author: Duley JA
Year: 1982
Journal: Biochem Genet
Title: Biochemical genetics of aldehyde reductase in the mouse: Ahr-1--a new locus linked to the alcohol dehydrogenase gene complex on chromosome 3.
Volume: 20
Issue: 11-12
Pages: 1067-83
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First Author: Eicher EM
Year: 1980
Journal: J Hered
Title: Assignment of LH XVI to chromosome 3 in the mouse.
Volume: 71
Issue: 5
Pages: 315-8
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First Author: van Buul PP
Year: 1991
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Volume: 251
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Year: 2014
Journal: PLoS Genet
Title: Mucolipin co-deficiency causes accelerated endolysosomal vacuolation of enterocytes and failure-to-thrive from birth to weaning.
Volume: 10
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Pages: e1004833
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Year: 2006
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Title: Cochlear developmental defect and background-dependent hearing thresholds in the Jackson circler (jc) mutant mouse.
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Year: 1960
Journal: Z Vererbungsl
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First Author: Lane PW
Year: 1972
Journal: J Hered
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Issue: 3
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Year: 2007
Journal: J Comp Neurol
Title: Vestibular ganglion neurons survive hair cell defects in jerker, shaker, and Varitint-waddler mutants and downregulate calretinin expression.
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First Author: Lane PW
Year: 1979
Journal: J Hered
Title: Gene order in linkage group XVI of the house mouse.
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Year: 2006
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Year: 2010
Journal: J Assoc Res Otolaryngol
Title: A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.
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Issue: 1
Pages: 27-37
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First Author: Silvers WK
Year: 1979
Title: The Coat Colors of Mice; A Model for Mammalian Gene Action and Interaction
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Year: 2009
Journal: EMBO J
Title: Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.
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Issue: 10
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First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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