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Search results 1 to 100 out of 133 for Mcph1

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Type Details Score
Gene
79648 | MCPH1
Type: gene
Organism: human
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Gene
100125236 | MCPH1
Type: gene
Organism: cattle
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Gene
100125976 | MCPH1
Type: gene
Organism: chicken
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Gene
678616 | mcph1
Type: gene
Organism: zebrafish
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Gene
100038095 | mcph1
Type: gene
Organism: frog, western clawed
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Gene
106999655 | MCPH1
Type: gene
Organism: macaque, rhesus
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Gene
306594 | Mcph1
Type: gene
Organism: rat
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Gene
442960 | MCPH1
Type: gene
Organism: dog, domestic
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Gene
449589 | MCPH1
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:2443308 | Mcph1
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
100287015 | MCPH1-DT
Type: gene
Organism: human
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Gene
100507530 | MCPH1-AS1
Type: gene
Organism: human
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Publication
23516444 | J:199385
First Author: Chen J
Year: 2013
Journal: PLoS One
Title: Mcph1-deficient mice reveal a role for MCPH1 in otitis media.
Volume: 8
Issue: 3
Pages: e58156
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Publication
32294449 | J:304136
First Author: Journiac N
Year: 2020
Journal: Cell Rep
Title: Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly.
Volume: 31
Issue: 2
Pages: 107506
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Publication
23683352 | J:261356
First Author: Zhou ZW
Year: 2013
Journal: DNA Repair (Amst)
Title: DNA damage response in microcephaly development of MCPH1 mouse model.
Volume: 12
Issue: 8
Pages: 645-55
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Publication
29150431 | J:257511
First Author: Liu X
Year: 2017
Journal: EMBO J
Title: The E3 ubiquitin ligase APC/CCdh1 degrades MCPH1 after MCPH1-βTrCP2-Cdc25A-mediated mitotic entry to ensure neurogenesis.
Volume: 36
Issue: 24
Pages: 3666-3681
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Publication
20169082 | J:157993
First Author: Trimborn M
Year: 2010
Journal: PLoS One
Title: Establishment of a mouse model with misregulated chromosome condensation due to defective Mcph1 function.
Volume: 5
Issue: 2
Pages: e9242
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Publication
36078123 | J:328987
 
First Author: Wang Y
Year: 2022
Journal: Cells
Title: The Central Domain of MCPH1 Controls Development of the Cerebral Cortex and Gonads in Mice.
Volume: 11
Issue: 17
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Publication
33542216 | J:307535
First Author: Liu X
Year: 2021
Journal: Cell Death Dis
Title: The N-terminal BRCT domain determines MCPH1 function in brain development and fertility.
Volume: 12
Issue: 2
Pages: 143
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Publication
21947081 | J:180706
First Author: Gruber R
Year: 2011
Journal: Nat Cell Biol
Title: MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway.
Volume: 13
Issue: 11
Pages: 1325-34
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DO Term
DOID:0070285 | primary autosomal recessive microcephaly 1
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Publication
25870538 | J:256065
 
First Author: Pulvers JN
Year: 2015
Journal: Front Cell Neurosci
Title: MCPH1: a window into brain development and evolution.
Volume: 9
Pages: 92
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Publication
25362854 | J:224255
First Author: Liang Y
Year: 2015
Journal: Oncogene
Title: Mcph1/Brit1 deficiency promotes genomic instability and tumor formation in a mouse model.
Volume: 34
Issue: 33
Pages: 4368-78
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Publication
21737879 | J:176173
First Author: Passemard S
Year: 2011
Journal: J Clin Invest
Title: VIP blockade leads to microcephaly in mice via disruption of Mcph1-Chk1 signaling.
Volume: 121
Issue: 8
Pages: 3071-87
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Protein Coding Gene
MGP_CAROLIEiJ_G0030862 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033403 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033384 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033314 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033384 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033097 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2443308 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033896 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032419 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033070 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033224 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0033317 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033209 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033913 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032132 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032535 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021326 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031973 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
20107607 | J:156371
First Author: Liang Y
Year: 2010
Journal: PLoS Genet
Title: BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice.
Volume: 6
Issue: 1
Pages: e1000826
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Publication
25646416 | J:220012
First Author: Keskin DB
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Physical detection of influenza A epitopes identifies a stealth subset on human lung epithelium evading natural CD8 immunity.
Volume: 112
Issue: 7
Pages: 2151-6
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Publication
27130449 | J:231900
First Author: Lin SI
Year: 2016
Journal: Cancer Lett
Title: Chimeric peptide containing both B and T cells epitope of tumor-associated antigen L6 enhances anti-tumor effects in HLA-A2 transgenic mice.
Volume: 377
Issue: 2
Pages: 126-33
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Publication
35404405 | J:338870
First Author: Chakraborty P
Year: 2022
Journal: Cancer Res
Title: Carbon Monoxide Activates PERK-Regulated Autophagy to Induce Immunometabolic Reprogramming and Boost Antitumor T-cell Function.
Volume: 82
Issue: 10
Pages: 1969-1990
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Publication
17045207 | J:114975
First Author: Yang J
Year: 2006
Journal: Cancer Cell
Title: Targeting beta2-microglobulin for induction of tumor apoptosis in human hematological malignancies.
Volume: 10
Issue: 4
Pages: 295-307
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Publication
24371056 | J:213029
First Author: Wang Z
Year: 2014
Journal: J Virol
Title: Adenoviral delivery of recombinant hepatitis B virus expressing foreign antigenic epitopes for immunotherapy of persistent viral infection.
Volume: 88
Issue: 5
Pages: 3004-15
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Publication
- | J:308712
     
First Author: Carter B
Year: 2021
Journal: bioRxiv
Title: Preliminary immunogenicity of a Pan-COVID-19 T cell vaccine in HLA-A*02:01 mice.
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Publication
30817223 | J:291802
First Author: Calviño-Sampedro C
Year: 2019
Journal: FASEB J
Title: Naturally presented HLA class I-restricted epitopes from the neurotrophic factor S100-β are targets of the autoimmune response in type 1 diabetes.
Volume: 33
Issue: 5
Pages: 6390-6401
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Publication
24313934 | J:284897
 
First Author: Lee J
Year: 2013
Journal: BMC Immunol
Title: Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice.
Volume: 14
Pages: 53
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GXD Expression
GXD Expression
   
Probe: MGI:5476921
Assay Type: Western blot
Annotation Date: 2013-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284222
Stage: TS22
Assay Id: MGI:5476923
Age: embryonic day 14.5
Image: S2
Specimen Label: Mcph1-ctr 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5476921
Assay Type: Western blot
Annotation Date: 2013-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284222
Stage: TS22
Assay Id: MGI:5476923
Age: embryonic day 14.5
Image: S2
Specimen Label: Mcph1-ctr 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5476921
Assay Type: Western blot
Annotation Date: 2013-05-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284222
Stage: TS22
Assay Id: MGI:5476923
Age: embryonic day 14.5
Image: S2
Specimen Label: Mcph1-del 1
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5476921
Assay Type: Western blot
Annotation Date: 2013-05-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284222
Stage: TS22
Assay Id: MGI:5476923
Age: embryonic day 14.5
Image: S2
Specimen Label: Mcph1-del 2
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5476846
Assay Type: RT-PCR
Annotation Date: 2013-05-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689528
Stage: TS28
Assay Id: MGI:5476917
Age: postnatal
Image: S2
Specimen Label: 2
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5476833
Assay Type: RT-PCR
Annotation Date: 2013-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689528
Stage: TS28
Assay Id: MGI:5476918
Age: postnatal
Image: S2
Specimen Label: 7
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:5476846
Assay Type: RT-PCR
Annotation Date: 2013-05-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5476917
Age: postnatal
Image: S2
Specimen Label: 3
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5476833
Assay Type: RT-PCR
Annotation Date: 2013-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5476918
Age: postnatal
Image: S2
Specimen Label: 8
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:5476846
Assay Type: RT-PCR
Annotation Date: 2013-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5476917
Age: postnatal
Image: S2
Specimen Label: 1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5476833
Assay Type: RT-PCR
Annotation Date: 2013-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5476918
Age: postnatal
Image: S2
Specimen Label: 6
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:5476819
Assay Type: RNA in situ
Annotation Date: 2013-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5476820
Age: embryonic day 15.5
Image: S1d/e & f
Specimen Label: S1d/e & f
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5476819
Assay Type: RNA in situ
Annotation Date: 2013-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5476820
Age: embryonic day 13.5
Image: S1a/b & c
Specimen Label: S1a/b & c
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5476819
Assay Type: RNA in situ
Annotation Date: 2013-05-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3270427
Stage: TS27
Assay Id: MGI:5476820
Age: postnatal day 0
Image: S1g/h & i
Specimen Label: S1g/h & i
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:642348
Assay Type: RNA in situ
Annotation Date: 2024-04-24
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7623573
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5476819
Assay Type: RNA in situ
Annotation Date: 2013-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5476820
Age: embryonic day 13.5
Image: S1a/b & c
Note: Expression was detected in the walls of the lateral ventricles.
Specimen Label: S1a/b & c
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5476819
Assay Type: RNA in situ
Annotation Date: 2013-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5476820
Age: postnatal day 0
Image: S1g/h & i
Specimen Label: S1g/h & i
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5476819
Assay Type: RNA in situ
Annotation Date: 2013-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5476820
Age: embryonic day 15.5
Image: S1d/e & f
Specimen Label: S1d/e & f
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5476819
Assay Type: RNA in situ
Annotation Date: 2013-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5476820
Age: embryonic day 13.5
Image: S1a/b & c
Specimen Label: S1a/b & c
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:642348
Assay Type: RNA in situ
Annotation Date: 2024-04-24
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7623573
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5476819
Assay Type: RNA in situ
Annotation Date: 2013-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267923
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5476820
Age: embryonic day 15.5
Image: S1d/e & f
Specimen Label: S1d/e & f
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5476819
Assay Type: RNA in situ
Annotation Date: 2013-05-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3270727
Stage: TS27
Assay Id: MGI:5476820
Age: postnatal day 0
Image: S1g/h & i
Specimen Label: S1g/h & i
Detected: false
Specimen Num: 3
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Publication
19487422 | J:149509
First Author: Strowig T
Year: 2009
Journal: J Exp Med
Title: Priming of protective T cell responses against virus-induced tumors in mice with human immune system components.
Volume: 206
Issue: 6
Pages: 1423-34
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Publication
8786307 | J:31937
First Author: Newberg MH
Year: 1996
Journal: J Immunol
Title: Importance of MHC class 1 alpha2 and alpha3 domains in the recognition of self and non-self MHC molecules.
Volume: 156
Issue: 7
Pages: 2473-80
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Publication
30728330 | J:279710
 
First Author: Smirnova NF
Year: 2019
Journal: JCI Insight
Title: Inhibition of B cell-dependent lymphoid follicle formation prevents lymphocytic bronchiolitis after lung transplantation.
Volume: 4
Issue: 3
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Publication
25733871 | J:220313
First Author: Ge C
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: BRUCE regulates DNA double-strand break response by promoting USP8 deubiquitination of BRIT1.
Volume: 112
Issue: 11
Pages: E1210-9
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Publication
2464645 | J:52612
First Author: Le AX
Year: 1989
Journal: J Immunol
Title: Cytotoxic T cell responses in HLA-A2.1 transgenic mice. Recognition of HLA alloantigens and utilization of HLA-A2.1 as a restriction element.
Volume: 142
Issue: 4
Pages: 1366-71
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Publication
33951431 | J:307117
First Author: Caduff N
Year: 2021
Journal: Cell Rep
Title: KSHV infection drives poorly cytotoxic CD56-negative natural killer cell differentiation in vivo upon KSHV/EBV dual infection.
Volume: 35
Issue: 5
Pages: 109056
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Publication
21521873 | J:177952
First Author: Whitfield-Larry F
Year: 2011
Journal: Diabetes
Title: HLA-A2-matched peripheral blood mononuclear cells from type 1 diabetic patients, but not nondiabetic donors, transfer insulitis to NOD-scid/γc(null)/HLA-A2 transgenic mice concurrent with the expansion of islet-specific CD8+ T cells.
Volume: 60
Issue: 6
Pages: 1726-33
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Publication
23833235 | J:205706
First Author: Billerbeck E
Year: 2013
Journal: J Immunol
Title: Characterization of human antiviral adaptive immune responses during hepatotropic virus infection in HLA-transgenic human immune system mice.
Volume: 191
Issue: 4
Pages: 1753-64
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Publication
28724724 | J:244095
     
First Author: Yen WF
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: BRCT-domain protein BRIT1 influences class switch recombination.
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Publication
36070233 | J:337575
First Author: Webber AM
Year: 2022
Journal: Blood
Title: Antigen-guided depletion of anti-HLA antibody-producing cells by HLA-Fc fusion proteins.
Volume: 140
Issue: 16
Pages: 1803-1815
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Publication
12361980 | J:109851
First Author: Marron MP
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Functional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice.
Volume: 99
Issue: 21
Pages: 13753-8
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Publication
15308121 | J:91764
First Author: Banuelos SJ
Year: 2004
Journal: Clin Immunol
Title: Rejection of human islets and human HLA-A2.1 transgenic mouse islets by alloreactive human lymphocytes in immunodeficient NOD-scid and NOD-Rag1(null)Prf1(null) mice.
Volume: 112
Issue: 3
Pages: 273-83
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Publication
20130175 | J:157933
First Author: Zhao G
Year: 2010
Journal: J Neurosci
Title: Gamma-secretase composed of PS1/Pen2/Aph1a can cleave notch and amyloid precursor protein in the absence of nicastrin.
Volume: 30
Issue: 5
Pages: 1648-56
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Publication
17259968 | J:142414
First Author: Shultz LD
Year: 2007
Journal: Nat Rev Immunol
Title: Humanized mice in translational biomedical research.
Volume: 7
Issue: 2
Pages: 118-30
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Publication
30487575 | J:267972
First Author: Douam F
Year: 2018
Journal: Nat Commun
Title: Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses.
Volume: 9
Issue: 1
Pages: 5031
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Publication
31412253 | J:286931
First Author: Chakraborty P
Year: 2019
Journal: Cell Rep
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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