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Search results 1 to 92 out of 92 for Mcub

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Huo J
Year: 2020
Journal: Circ Res
Title: MCUb Induction Protects the Heart From Postischemic Remodeling.
Volume: 127
Issue: 3
Pages: 379-390
Publication
First Author: Feno S
Year: 2021
Journal: Sci Signal
Title: The dominant-negative mitochondrial calcium uniporter subunit MCUb drives macrophage polarization during skeletal muscle regeneration.
Volume: 14
Issue: 707
Pages: eabf3838
Publication
First Author: Huo J
Year: 2023
Journal: Cell Rep
Title: MCUb is an inducible regulator of calcium-dependent mitochondrial metabolism and substrate utilization in muscle.
Volume: 42
Issue: 11
Pages: 113465
Publication
First Author: Lambert JP
Year: 2019
Journal: Circulation
Title: MCUB Regulates the Molecular Composition of the Mitochondrial Calcium Uniporter Channel to Limit Mitochondrial Calcium Overload During Stress.
Volume: 140
Issue: 21
Pages: 1720-1733
Publication
First Author: Raffaello A
Year: 2013
Journal: EMBO J
Title: The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit.
Volume: 32
Issue: 17
Pages: 2362-76
Publication
First Author: Ghatge M
Year: 2023
Journal: J Thromb Haemost
Title: Mitochondrial calcium uniporter b deletion inhibits platelet function and reduces susceptibility to arterial thrombosis.
Volume: 21
Issue: 8
Pages: 2163-2174
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Márkus NM
Year: 2016
Journal: PLoS One
Title: Expression of mRNA Encoding Mcu and Other Mitochondrial Calcium Regulatory Genes Depends on Cell Type, Neuronal Subtype, and Ca2+ Signaling.
Volume: 11
Issue: 2
Pages: e0148164
Publication
First Author: Singh R
Year: 2022
Journal: Sci Adv
Title: Uncontrolled mitochondrial calcium uptake underlies the pathogenesis of neurodegeneration in MICU1-deficient mice and patients.
Volume: 8
Issue: 11
Pages: eabj4716
Publication
First Author: Quina LA
Year: 2009
Journal: J Neurosci
Title: Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.
Volume: 29
Issue: 45
Pages: 14309-22
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Protein
Organism: Mus musculus/domesticus
Length: 252  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: true
Allele
Name: mitochondrial calcium uniporter dominant negative beta subunit; targeted mutation 1d, Mouse Biology Program, UC Davis
Allele Type: Targeted
Attribute String: Null/knockout
Protein
Organism: Mus musculus/domesticus
Length: 345  
Fragment?: false
Allele
Name: transgene insertion, Jeffery Molkentin
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: This entry represents the MCU family, whose members include MCU and MCUb from mammals and MCU1-6 from Arabidopsis. MCU is a mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria [, , ]. MCUb negatively regulates the activity of MCU [].
Publication
First Author: Johnson KR
Year: 2003
Journal: Genomics
Title: Curly bare (cub), a new mouse mutation on chromosome 11 causing skin and hair abnormalities, and a modifier gene (mcub) on chromosome 5.
Volume: 81
Issue: 1
Pages: 6-14
Publication
First Author: Siggs OM
Year: 2014
Journal: Biol Open
Title: Genetic interaction implicates iRhom2 in the regulation of EGF receptor signalling in mice.
Volume: 3
Issue: 12
Pages: 1151-7
Publication
First Author: Baughman JM
Year: 2011
Journal: Nature
Title: Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.
Volume: 476
Issue: 7360
Pages: 341-5
Publication
First Author: De Stefani D
Year: 2011
Journal: Nature
Title: A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter.
Volume: 476
Issue: 7360
Pages: 336-40
Protein
Organism: Mus musculus/domesticus
Length: 350  
Fragment?: false
Publication
First Author: Mallilankaraman K
Year: 2012
Journal: Cell
Title: MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival.
Volume: 151
Issue: 3
Pages: 630-44
Allele
Name: amphiregulin; modifier of curly bare
Allele Type: Spontaneous
Attribute String: Null/knockout
Publication
First Author: Raugh A
Year: 2023
Journal: Sci Rep
Title: The amphiregulin/EGFR axis has limited contribution in controlling autoimmune diabetes.
Volume: 13
Issue: 1
Pages: 18653
Genotype
Symbol: Areg/Areg
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Strain
Attribute String: congenic, mutant strain
Publication
First Author: Hosur V
Year: 2017
Journal: BMC Res Notes
Title: Tissue-specific role of RHBDF2 in cutaneous wound healing and hyperproliferative skin disease.
Volume: 10
Issue: 1
Pages: 573
Genotype
Symbol: Rhbdf2/Rhbdf2 Areg/Areg<+>
Background: involves: C57BL/6J * STOCK a us/J * V/LeJ
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Areg/Areg Rhbdf2/Rhbdf2
Background: involves: C57BL/6J * V/LeJ
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Areg/Areg Rhbdf2/Rhbdf2
Background: involves: C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Hosur V
Year: 2017
Journal: Biol Open
Title: Genetic deletion of amphiregulin restores the normal skin phenotype in a mouse model of the human skin disease tylosis.
Volume: 6
Issue: 8
Pages: 1174-1179
Publication  
First Author: Xu H
Year: 2023
Journal: Metabolism
Title: Syntaxin17 contributes to obesity cardiomyopathy through promoting mitochondrial Ca(2+) overload in a Parkin-MCUb-dependent manner.
Volume: 143
Pages: 155551
Publication
First Author: Hosur V
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin.
Volume: 111
Issue: 21
Pages: E2200-9
Publication  
First Author: Hosur V
Year: 2018
Journal: Front Genet
Title: RHBDF2-Regulated Growth Factor Signaling in a Rare Human Disease, Tylosis With Esophageal Cancer: What Can We Learn From Murine Models?
Volume: 9
Pages: 233
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112