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Search results 1 to 100 out of 684 for Mecom

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication  
First Author: Juneja SC
Year: 2014
Journal: Bone
Title: Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia.
Volume: 60
Pages: 148-61
Publication
First Author: Sayadi A
Year: 2016
Journal: Oncogene
Title: Functional features of EVI1 and EVI1Δ324 isoforms of MECOM gene in genome-wide transcription regulation and oncogenicity.
Volume: 35
Issue: 18
Pages: 2311-21
Publication
First Author: Backx E
Year: 2021
Journal: Cell Death Differ
Title: MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions.
Volume: 28
Issue: 9
Pages: 2601-2615
Publication
First Author: Wimmer K
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Comparative expression analysis of the antagonistic transcription factors EVI1 and MDS1-EVI1 in murine tissues and during in vitro hematopoietic differentiation.
Volume: 252
Issue: 3
Pages: 691-6
Publication
First Author: Matsugi T
Year: 1990
Journal: Mol Cell Biol
Title: Identification, nuclear localization, and DNA-binding activity of the zinc finger protein encoded by the Evi-1 myeloid transforming gene.
Volume: 10
Issue: 3
Pages: 1259-64
Publication
First Author: Shimabe M
Year: 2009
Journal: Oncogene
Title: Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells.
Volume: 28
Issue: 49
Pages: 4364-74
Publication
First Author: Hoyt PR
Year: 1997
Journal: Mech Dev
Title: The Evi1 proto-oncogene is required at midgestation for neural, heart, and paraxial mesenchyme development.
Volume: 65
Issue: 1-2
Pages: 55-70
Publication
First Author: Yuasa H
Year: 2005
Journal: EMBO J
Title: Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression.
Volume: 24
Issue: 11
Pages: 1976-87
ncRNA Gene
Type: lncRNA_gene
Organism: mouse, laboratory
Publication
First Author: Morishita K
Year: 1988
Journal: Cell
Title: Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines.
Volume: 54
Issue: 6
Pages: 831-40
Publication
First Author: Spensberger D
Year: 2008
Journal: FEBS Lett
Title: A novel interaction between the proto-oncogene Evi1 and histone methyltransferases, SUV39H1 and G9a.
Volume: 582
Issue: 18
Pages: 2761-7
Publication
First Author: Pinheiro I
Year: 2012
Journal: Cell
Title: Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.
Volume: 150
Issue: 5
Pages: 948-60
Publication
First Author: Zhang Y
Year: 2013
Journal: Blood
Title: Essential role of PR-domain protein MDS1-EVI1 in MLL-AF9 leukemia.
Volume: 122
Issue: 16
Pages: 2888-92
Publication  
First Author: McGlynn KA
Year: 2020
Journal: Exp Hematol
Title: Prdm3 and Prdm16 cooperatively maintain hematopoiesis and clonogenic potential.
Volume: 85
Pages: 20-32.e3
Publication
First Author: Zhang Y
Year: 2021
Journal: Cell Rep
Title: Mds1CreERT2, an inducible Cre allele specific to adult-repopulating hematopoietic stem cells.
Volume: 36
Issue: 7
Pages: 109562
Publication
First Author: Zhang Y
Year: 2011
Journal: Blood
Title: PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function.
Volume: 118
Issue: 14
Pages: 3853-61
Publication
First Author: Tanaka A
Year: 2022
Journal: Blood
Title: Aberrant EVI1 splicing contributes to EVI1-rearranged leukemia.
Volume: 140
Issue: 8
Pages: 875-888
UniProt Feature
Begin: 1
Description: Histone-lysine N-methyltransferase MECOM
Type: chain
End: 1232
Publication
First Author: Nagamachi A
Year: 2010
Journal: Dev Biol
Title: A 5' untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model.
Volume: 345
Issue: 2
Pages: 226-36
Publication
First Author: Christodoulou C
Year: 2020
Journal: Nature
Title: Live-animal imaging of native haematopoietic stem and progenitor cells.
Volume: 578
Issue: 7794
Pages: 278-283
Publication
First Author: Garside VC
Year: 2015
Journal: Development
Title: SOX9 modulates the expression of key transcription factors required for heart valve development.
Volume: 142
Issue: 24
Pages: 4340-50
Publication  
First Author: Azar A
Year: 2022
Journal: Front Genet
Title: Trans-cortical vessels in the mouse temporal bulla bone are a means to recruit myeloid cells in chronic otitis media and limit peripheral leukogram changes.
Volume: 13
Pages: 985214
Publication
First Author: Yokomizo T
Year: 2022
Journal: Nature
Title: Independent origins of fetal liver haematopoietic stem and progenitor cells.
Volume: 609
Issue: 7928
Pages: 779-784
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Goyama S
Year: 2008
Journal: Cell Stem Cell
Title: Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells.
Volume: 3
Issue: 2
Pages: 207-20
Publication
First Author: Arai S
Year: 2011
Journal: Blood
Title: Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cells.
Volume: 117
Issue: 23
Pages: 6304-14
Publication
First Author: Sato T
Year: 2014
Journal: Oncogene
Title: Evi1 defines leukemia-initiating capacity and tyrosine kinase inhibitor resistance in chronic myeloid leukemia.
Volume: 33
Issue: 42
Pages: 5028-38
Publication
First Author: Kataoka K
Year: 2011
Journal: J Exp Med
Title: Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity.
Volume: 208
Issue: 12
Pages: 2403-16
Publication
First Author: Perkins AS
Year: 1996
Journal: J Biol Chem
Title: Zinc fingers 1-7 of EVI1 fail to bind to the GATA motif by itself but require the core site GACAAGATA for binding.
Volume: 271
Issue: 2
Pages: 1104-10
Publication
First Author: Chakraborty S
Year: 2001
Journal: J Biol Chem
Title: Interaction of EVI1 with cAMP-responsive element-binding protein-binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles.
Volume: 276
Issue: 48
Pages: 44936-43
Publication
First Author: Hirai H
Year: 1999
Journal: Int J Biochem Cell Biol
Title: The transcription factor Evi-1.
Volume: 31
Issue: 12
Pages: 1367-71
Publication
First Author: Jółkowska J
Year: 2000
Journal: Leuk Res
Title: The EVI-1 gene--its role in pathogenesis of human leukemias.
Volume: 24
Issue: 7
Pages: 553-8
Publication
First Author: Louz D
Year: 2000
Journal: Leukemia
Title: Erythroid defects and increased retrovirally-induced tumor formation in Evi1 transgenic mice.
Volume: 14
Issue: 11
Pages: 1876-84
Publication
First Author: Chattopadhyay SK
Year: 1980
Journal: Proc Natl Acad Sci U S A
Title: Structure of endogenous murine leukemia virus DNA in mouse genomes.
Volume: 77
Issue: 10
Pages: 5774-8
Publication
First Author: Mucenski ML
Year: 1988
Journal: Mol Cell Biol
Title: Identification of a common ecotropic viral integration site, Evi-1, in the DNA of AKXD murine myeloid tumors.
Volume: 8
Issue: 1
Pages: 301-8
Publication  
First Author: Copeland NG
Year: 1990
Journal: Adv Cancer Res
Title: Retroviral integration in murine myeloid tumors to identify Evi-1, a novel locus encoding a zinc-finger protein.
Volume: 54
Pages: 141-57
Publication
First Author: Bordereaux D
Year: 1990
Journal: Oncogene
Title: Alternative splicing of the Evi-1 zinc finger gene generates mRNAs which differ by the number of zinc finger motifs.
Volume: 5
Issue: 6
Pages: 925-7
Publication
First Author: Perkins AS
Year: 1991
Journal: Development
Title: Patterns of Evi-1 expression in embryonic and adult tissues suggest that Evi-1 plays an important regulatory role in mouse development.
Volume: 111
Issue: 2
Pages: 479-87
Publication
First Author: Morishita K
Year: 1992
Journal: Mol Cell Biol
Title: Expression of the Evi-1 zinc finger gene in 32Dc13 myeloid cells blocks granulocytic differentiation in response to granulocyte colony-stimulating factor.
Volume: 12
Issue: 1
Pages: 183-9
Publication
First Author: Bartholomew C
Year: 1994
Journal: Oncogene
Title: Induction of two alternatively spliced evi-1 proto-oncogene transcripts by cAMP in kidney cells.
Volume: 9
Issue: 3
Pages: 939-42
Publication
First Author: Funabiki T
Year: 1994
Journal: Oncogene
Title: The carboxyl domain of zinc fingers of the Evi-1 myeloid transforming gene binds a consensus sequence of GAAGATGAG.
Volume: 9
Issue: 6
Pages: 1575-81
Publication
First Author: Dickstein J
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Methylation and silencing of miRNA-124 by EVI1 and self-renewal exhaustion of hematopoietic stem cells in murine myelodysplastic syndrome.
Volume: 107
Issue: 21
Pages: 9783-8
Publication
First Author: Ishibashi J
Year: 2012
Journal: Mol Cell Biol
Title: An Evi1-C/EBPβ complex controls peroxisome proliferator-activated receptor γ2 gene expression to initiate white fat cell differentiation.
Volume: 32
Issue: 12
Pages: 2289-99
Publication
First Author: White DJ
Year: 2013
Journal: PLoS One
Title: Phosphorylation of the leukemic oncoprotein EVI1 on serine 196 modulates DNA binding, transcriptional repression and transforming ability.
Volume: 8
Issue: 6
Pages: e66510
Publication
First Author: Maicas M
Year: 2017
Journal: Biochim Biophys Acta
Title: The MDS and EVI1 complex locus (MECOM) isoforms regulate their own transcription and have different roles in the transformation of hematopoietic stem and progenitor cells.
Volume: 1860
Issue: 6
Pages: 721-729
Publication
First Author: Ye J
Year: 2020
Journal: Cell Death Dis
Title: PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response.
Volume: 11
Issue: 3
Pages: 187
GXD Expression    
Probe: MGI:2659107
Assay Type: RT-PCR
Annotation Date: 2003-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737323
Stage: TS23
Assay Id: MGI:2659111
Age: embryonic day 15.5
Image: 3
Specimen Label: 15.5 PC
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2659107
Assay Type: RT-PCR
Annotation Date: 2003-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737325
Stage: TS25
Assay Id: MGI:2659111
Age: embryonic day 17.5
Image: 3
Specimen Label: 17.5 PC
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2659107
Assay Type: RT-PCR
Annotation Date: 2003-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2659111
Age: postnatal adult
Image: 3
Specimen Label: Adult
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2659107
Assay Type: RT-PCR
Annotation Date: 2003-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2659111
Age: postnatal adult
Image: 3
Specimen Label: Lung
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:2659108
Assay Type: RT-PCR
Annotation Date: 2003-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737323
Stage: TS23
Assay Id: MGI:2659112
Age: embryonic day 15.5
Image: 3
Specimen Label: 15.5 PC
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2659108
Assay Type: RT-PCR
Annotation Date: 2003-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737325
Stage: TS25
Assay Id: MGI:2659112
Age: embryonic day 17.5
Image: 3
Specimen Label: 17.5 PC
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2659108
Assay Type: RT-PCR
Annotation Date: 2003-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2659112
Age: postnatal adult
Image: 3
Specimen Label: Adult
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2659108
Assay Type: RT-PCR
Annotation Date: 2003-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2659112
Age: postnatal adult
Image: 3
Specimen Label: Lung
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:2659106
Assay Type: Northern blot
Annotation Date: 2003-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2659113
Age: postnatal adult
Specimen Label: kidney
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2659106
Assay Type: Northern blot
Annotation Date: 2003-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2659113
Age: postnatal adult
Specimen Label: lung
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2659106
Assay Type: Northern blot
Annotation Date: 2003-05-20
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:2659113
Age: postnatal adult
Specimen Label: ovaries
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2659107
Assay Type: RT-PCR
Annotation Date: 2012-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:5441466
Age: embryonic day 10.5
Image: 9
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2659107
Assay Type: RT-PCR
Annotation Date: 2012-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:5441466
Age: embryonic day 10.5
Image: 9
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2659107
Assay Type: RT-PCR
Annotation Date: 2012-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:5441466
Age: embryonic day 10.5
Image: 9
Specimen Label: -/-
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5646232
Assay Type: Northern blot
Annotation Date: 2015-08-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5646248
Age: postnatal adult
Image: 1
Specimen Label: Lung
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5646233
Assay Type: Northern blot
Annotation Date: 2015-08-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5646249
Age: postnatal adult
Image: 1
Specimen Label: Heart
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5646232
Assay Type: Northern blot
Annotation Date: 2015-08-06
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:5646248
Age: postnatal adult
Image: 1
Specimen Label: Ovary
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5646233
Assay Type: Northern blot
Annotation Date: 2015-08-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5646249
Age: postnatal adult
Image: 1
Specimen Label: Kidney
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5646233
Assay Type: Northern blot
Annotation Date: 2015-08-06
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:5646249
Age: postnatal adult
Image: 1
Specimen Label: Uterus
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5646255
Assay Type: Northern blot
Annotation Date: 2015-08-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5646256
Age: postnatal adult
Specimen Label: liver
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5646255
Assay Type: Northern blot
Annotation Date: 2015-08-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:5646256
Age: postnatal adult
Specimen Label: intestine
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5646255
Assay Type: Northern blot
Annotation Date: 2015-08-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5646256
Age: postnatal adult
Specimen Label: thymus
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5646255
Assay Type: Northern blot
Annotation Date: 2015-08-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5646256
Age: postnatal adult
Specimen Label: spleen
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5646255
Assay Type: Northern blot
Annotation Date: 2015-08-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:5646256
Age: postnatal adult
Specimen Label: stomach
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5646255
Assay Type: Northern blot
Annotation Date: 2015-08-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5646256
Age: postnatal adult
Specimen Label: brain
Detected: true
Specimen Num: 6