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Search results 1 to 100 out of 1527 for Mecp2

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Type Details Score
Gene
4204 | MECP2
Type: gene
Organism: human
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Gene
539629 | MECP2
Type: gene
Organism: cattle
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Gene
335250 | mecp2
Type: gene
Organism: zebrafish
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Gene
700174 | MECP2
Type: gene
Organism: macaque, rhesus
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Gene
100216110 | mecp2
Type: gene
Organism: frog, western clawed
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Gene
key_41403 | MECP2
Type: gene
Organism: hamster, golden
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Gene
key_41402 | MECP2
Type: gene
Organism: orangutan, Bornean
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Gene
29386 | Mecp2
Type: gene
Organism: rat
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Gene
612973 | MECP2
Type: gene
Organism: dog, domestic
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Gene
465936 | MECP2
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:99918 | Mecp2
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
   
Probe: MGI:7450707
Assay Type: RT-PCR
Annotation Date: 2023-04-04
Strength: Present
Sex: Male
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7450710
Age: postnatal adult
Image: 5
Specimen Label: Mecp2 -/y
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7449272
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-03
Strength: Present
Sex: Male
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7449290
Age: postnatal
Image: 5B Mecp2 -/y
Note: Staining intensity was unaltered in the dentate gyrus of Mecp2<-/y> mice.
Specimen Label: 5B Mecp2 -/y
Detected: true
Specimen Num: 4
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Publication
27015692 | J:240854
 
First Author: Williams AA
Year: 2016
Journal: Neurobiol Dis
Title: MECP2 impairs neuronal structure by regulating KIBRA.
Volume: 91
Pages: 284-91
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Other Genome Feature
MGI:3573944 | Mecp2-2
Type: sequence_feature
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:7449272
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-03
Strength: Present
Sex: Male
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7449290
Age: postnatal
Image: 5B Wild type Mecp2 +/y
Specimen Label: 5B Wild type Mecp2 +/y
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7449274
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-03
Strength: Present
Sex: Male
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7449329
Age: postnatal
Image: 5B Wild type Mecp2 +/y
Specimen Label: 5B Wild type Mecp2 +/y
Detected: true
Specimen Num: 3
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Publication
32561780 | J:292308
First Author: Lee W
Year: 2020
Journal: Nat Commun
Title: MeCP2 regulates gene expression through recognition of H3K27me3.
Volume: 11
Issue: 1
Pages: 3140
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Publication
27008915 | J:236741
 
First Author: Rube HT
Year: 2016
Journal: Nat Commun
Title: Sequence features accurately predict genome-wide MeCP2 binding in vivo.
Volume: 7
Pages: 11025
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Publication
15608638 | J:96437
First Author: Horike S
Year: 2005
Journal: Nat Genet
Title: Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome.
Volume: 37
Issue: 1
Pages: 31-40
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Publication
29412786 | J:323618
First Author: Khan AW
Year: 2017
Journal: Epigenetics
Title: MeCP2 interacts with chromosomal microRNAs in brain.
Volume: 12
Issue: 12
Pages: 1028-1037
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Publication
16354910 | J:104053
First Author: Viemari JC
Year: 2005
Journal: J Neurosci
Title: Mecp2 deficiency disrupts norepinephrine and respiratory systems in mice.
Volume: 25
Issue: 50
Pages: 11521-30
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Publication
28659760 | J:289561
 
First Author: Torres RF
Year: 2017
Journal: Front Mol Neurosci
Title: Mecp2 Mediates Experience-Dependent Transcriptional Upregulation of Ryanodine Receptor Type-3.
Volume: 10
Pages: 188
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Publication
37712894 | J:344468
First Author: Zlatic SA
Year: 2023
Journal: Hum Mol Genet
Title: Systemic proteome phenotypes reveal defective metabolic flexibility in Mecp2 mutants.
Volume: 33
Issue: 1
Pages: 12-32
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Publication
17920015 | J:126964
First Author: Chao HT
Year: 2007
Journal: Neuron
Title: MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number.
Volume: 56
Issue: 1
Pages: 58-65
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Other Genome Feature
MGI:3573943 | Mecp2-1
Type: sequence_feature
Organism: mouse, laboratory
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Publication
25008110 | J:215637
First Author: Lee W
Year: 2014
Journal: Hum Mol Genet
Title: MeCP2 regulates activity-dependent transcriptional responses in olfactory sensory neurons.
Volume: 23
Issue: 23
Pages: 6366-74
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Publication
23448145 | J:323642
First Author: Repunte-Canonigo V
Year: 2014
Journal: Addict Biol
Title: MeCP2 regulates ethanol sensitivity and intake.
Volume: 19
Issue: 5
Pages: 791-9
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Publication
22378884 | J:182685
First Author: Na ES
Year: 2012
Journal: J Neurosci
Title: A mouse model for MeCP2 duplication syndrome: MeCP2 overexpression impairs learning and memory and synaptic transmission.
Volume: 32
Issue: 9
Pages: 3109-17
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Publication
31784360 | J:286266
First Author: Clemens AW
Year: 2020
Journal: Mol Cell
Title: MeCP2 Represses Enhancers through Chromosome Topology-Associated DNA Methylation.
Volume: 77
Issue: 2
Pages: 279-293.e8
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Publication
24594659 | J:323665
First Author: Olson CO
Year: 2014
Journal: PLoS One
Title: Brain region-specific expression of MeCP2 isoforms correlates with DNA methylation within Mecp2 regulatory elements.
Volume: 9
Issue: 3
Pages: e90645
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Publication
23770587 | J:204723
First Author: Ebert DH
Year: 2013
Journal: Nature
Title: Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR.
Volume: 499
Issue: 7458
Pages: 341-5
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Publication
27288453 | J:237141
First Author: Kyle SM
Year: 2016
Journal: Hum Mol Genet
Title: MeCP2 co-ordinates liver lipid metabolism with the NCoR1/HDAC3 corepressor complex.
Volume: 25
Issue: 14
Pages: 3029-3041
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Publication
37871205 | J:342941
First Author: Tzeng CP
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Activity-induced MeCP2 phosphorylation regulates retinogeniculate synapse refinement.
Volume: 120
Issue: 44
Pages: e2310344120
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Publication
16543822 | J:107578
First Author: Picker JD
Year: 2006
Journal: Neuroreport
Title: An altered neonatal behavioral phenotype in Mecp2 mutant mice.
Volume: 17
Issue: 5
Pages: 541-4
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Publication
33737384 | J:311942
First Author: Shao Y
Year: 2021
Journal: Genes Dev
Title: Identification and characterization of conserved noncoding cis-regulatory elements that impact Mecp2 expression and neurological functions.
Volume: 35
Issue: 7-8
Pages: 489-494
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Publication
33561390 | J:309631
First Author: Tillotson R
Year: 2021
Journal: Mol Cell
Title: Neuronal non-CG methylation is an essential target for MeCP2 function.
Volume: 81
Issue: 6
Pages: 1260-1275.e12
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Publication
26237041 | J:225796
First Author: Lombardi LM
Year: 2015
Journal: J Clin Invest
Title: MECP2 disorders: from the clinic to mice and back.
Volume: 125
Issue: 8
Pages: 2914-23
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Publication
34282222 | J:313829
First Author: Villani C
Year: 2021
Journal: Sci Rep
Title: Fluoxetine increases brain MeCP2 immuno-positive cells in a female Mecp2 heterozygous mouse model of Rett syndrome through endogenous serotonin.
Volume: 11
Issue: 1
Pages: 14690
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Publication
21765426 | J:175890
First Author: Li H
Year: 2011
Journal: Nat Neurosci
Title: Loss of activity-induced phosphorylation of MeCP2 enhances synaptogenesis, LTP and spatial memory.
Volume: 14
Issue: 8
Pages: 1001-8
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Publication
29847590 | J:265313
First Author: Yagasaki Y
Year: 2018
Journal: PLoS One
Title: Experience-dependent MeCP2 expression in the excitatory cells of mouse visual thalamus.
Volume: 13
Issue: 5
Pages: e0198268
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Publication
33296675 | J:323617
First Author: Fioriniello S
Year: 2020
Journal: Stem Cell Reports
Title: MeCP2 and Major Satellite Forward RNA Cooperate for Pericentric Heterochromatin Organization.
Volume: 15
Issue: 6
Pages: 1317-1332
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Publication
16754645 | J:112026
First Author: Jordan C
Year: 2006
Journal: Hum Mol Genet
Title: Ube3a expression is not altered in Mecp2 mutant mice.
Volume: 15
Issue: 14
Pages: 2210-5
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Publication
30463906 | J:272570
First Author: Koerner MV
Year: 2018
Journal: Genes Dev
Title: Toxicity of overexpressed MeCP2 is independent of HDAC3 activity.
Volume: 32
Issue: 23-24
Pages: 1514-1524
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Publication
23462290 | J:198235
First Author: Pitcher MR
Year: 2013
Journal: Hum Mol Genet
Title: Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function.
Volume: 22
Issue: 13
Pages: 2626-33
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Publication
32526163 | J:297174
First Author: Xiang Y
Year: 2020
Journal: Mol Cell
Title: Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons.
Volume: 79
Issue: 1
Pages: 84-98.e9
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Publication
24671997 | J:210455
First Author: Deng JV
Year: 2014
Journal: J Neurosci
Title: MeCP2 phosphorylation limits psychostimulant-induced behavioral and neuronal plasticity.
Volume: 34
Issue: 13
Pages: 4519-27
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Publication
22262897 | J:179889
First Author: Qiu Z
Year: 2012
Journal: J Neurosci
Title: The Rett syndrome protein MeCP2 regulates synaptic scaling.
Volume: 32
Issue: 3
Pages: 989-94
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Publication
36848184 | J:334573
   
First Author: Bajikar SS
Year: 2023
Journal: Elife
Title: MeCP2 regulates Gdf11, a dosage-sensitive gene critical for neurological function.
Volume: 12
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Publication
17994015 | J:130774
First Author: Klein ME
Year: 2007
Journal: Nat Neurosci
Title: Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA.
Volume: 10
Issue: 12
Pages: 1513-4
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Publication
20200124 | J:323729
First Author: Zhang ZW
Year: 2010
Journal: J Neurophysiol
Title: MeCP2 is required for normal development of GABAergic circuits in the thalamus.
Volume: 103
Issue: 5
Pages: 2470-81
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Publication
24283265 | J:209637
First Author: Schaevitz LR
Year: 2013
Journal: Genes Brain Behav
Title: MeCP2 R168X male and female mutant mice exhibit Rett-like behavioral deficits.
Volume: 12
Issue: 7
Pages: 732-40
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Publication
22127389 | J:182049
First Author: Roux JC
Year: 2012
Journal: Neurobiol Dis
Title: Modification of Mecp2 dosage alters axonal transport through the Huntingtin/Hap1 pathway.
Volume: 45
Issue: 2
Pages: 786-95
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Publication
19386901 | J:158156
First Author: Maezawa I
Year: 2009
Journal: J Neurosci
Title: Rett syndrome astrocytes are abnormal and spread MeCP2 deficiency through gap junctions.
Volume: 29
Issue: 16
Pages: 5051-61
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DO Term
DOID:0111932 | severe congenital encephalopathy due to MECP2 mutation
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Publication
18159237 | J:130960
First Author: Miralvès J
Year: 2007
Journal: PLoS One
Title: High levels of MeCP2 depress MHC class I expression in neuronal cells.
Volume: 2
Issue: 12
Pages: e1354
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Publication
19710912 | J:152398
First Author: Rastegar M
Year: 2009
Journal: PLoS One
Title: MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy.
Volume: 4
Issue: 8
Pages: e6810
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Publication
27458802 | J:235289
   
First Author: Schafer DP
Year: 2016
Journal: Elife
Title: Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression.
Volume: 5
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Publication
24970834 | J:214143
   
First Author: Heckman LD
Year: 2014
Journal: Elife
Title: Rett-causing mutations reveal two domains critical for MeCP2 function and for toxicity in MECP2 duplication syndrome mice.
Volume: 3
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Publication
29019980 | J:252845
First Author: Tillotson R
Year: 2017
Journal: Nature
Title: Radically truncated MeCP2 rescues Rett syndrome-like neurological defects.
Volume: 550
Issue: 7676
Pages: 398-401
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Publication
23260135 | J:193327
First Author: Mellén M
Year: 2012
Journal: Cell
Title: MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.
Volume: 151
Issue: 7
Pages: 1417-30
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Publication
18321865 | J:135824
First Author: Kerr B
Year: 2008
Journal: Hum Mol Genet
Title: Defective body-weight regulation, motor control and abnormal social interactions in Mecp2 hypomorphic mice.
Volume: 17
Issue: 12
Pages: 1707-17
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Publication
26806603 | J:323664
 
First Author: Bittolo T
Year: 2016
Journal: Sci Rep
Title: Pharmacological treatment with mirtazapine rescues cortical atrophy and respiratory deficits in MeCP2 null mice.
Volume: 6
Pages: 19796
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Publication
29464197 | J:262199
 
First Author: Kahanovitch U
Year: 2018
Journal: eNeuro
Title: MeCP2 Deficiency Leads to Loss of Glial Kir4.1.
Volume: 5
Issue: 1
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Publication
23335972 | J:323667
First Author: Becker A
Year: 2013
Journal: PLoS One
Title: Direct homo- and hetero-interactions of MeCP2 and MBD2.
Volume: 8
Issue: 1
Pages: e53730
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Publication
22677942 | J:323994
First Author: Zocchi L
Year: 2012
Journal: Epigenetics
Title: SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression.
Volume: 7
Issue: 7
Pages: 695-700
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Publication
31352003 | J:293222
First Author: Moran-Salvador E
Year: 2019
Journal: Gastroenterology
Title: Fibrogenic Activity of MECP2 Is Regulated by Phosphorylation in Hepatic Stellate Cells.
Volume: 157
Issue: 5
Pages: 1398-1412.e9
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Publication
26185009 | J:318309
First Author: Mierau SB
Year: 2016
Journal: Biol Psychiatry
Title: Cell-Specific Regulation of N-Methyl-D-Aspartate Receptor Maturation by Mecp2 in Cortical Circuits.
Volume: 79
Issue: 9
Pages: 746-754
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Publication
19843474 | J:323728
First Author: Mann J
Year: 2010
Journal: Gastroenterology
Title: MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis.
Volume: 138
Issue: 2
Pages: 705-14, 714.e1-4
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Publication
28098153 | J:244378
 
First Author: Krishnan K
Year: 2017
Journal: Nat Commun
Title: MECP2 regulates cortical plasticity underlying a learned behaviour in adult female mice.
Volume: 8
Pages: 14077
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Publication
29637441 | J:323603
First Author: Montgomery KR
Year: 2018
Journal: Mol Neurobiol
Title: Elevated MeCP2 in Mice Causes Neurodegeneration Involving Tau Dysregulation and Excitotoxicity: Implications for the Understanding and Treatment of MeCP2 Triplication Syndrome.
Volume: 55
Issue: 12
Pages: 9057-9074
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Publication
15345242 | J:109708
First Author: Matarazzo V
Year: 2004
Journal: Mol Cell Neurosci
Title: The transcriptional repressor Mecp2 regulates terminal neuronal differentiation.
Volume: 27
Issue: 1
Pages: 44-58
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Publication
21982370 | J:178533
First Author: Cohen S
Year: 2011
Journal: Neuron
Title: Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function.
Volume: 72
Issue: 1
Pages: 72-85
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Publication
21909962 | J:323735
First Author: Pearson BL
Year: 2012
Journal: Behav Genet
Title: Mecp2 truncation in male mice promotes affiliative social behavior.
Volume: 42
Issue: 2
Pages: 299-312
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Publication
21880923 | J:176217
First Author: Gantz SC
Year: 2011
Journal: J Neurosci
Title: Loss of Mecp2 in substantia nigra dopamine neurons compromises the nigrostriatal pathway.
Volume: 31
Issue: 35
Pages: 12629-37
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Publication
26098633 | J:237891
First Author: Conti V
Year: 2015
Journal: PLoS One
Title: MeCP2 Affects Skeletal Muscle Growth and Morphology through Non Cell-Autonomous Mechanisms.
Volume: 10
Issue: 6
Pages: e0130183
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Publication
30923887 | J:294436
First Author: Martínez-Rodríguez E
Year: 2019
Journal: Brain Struct Funct
Title: Lack of MeCP2 leads to region-specific increase of doublecortin in the olfactory system.
Volume: 224
Issue: 4
Pages: 1647-1658
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Publication
23185431 | J:225070
First Author: Zachariah RM
Year: 2012
Journal: PLoS One
Title: Novel MeCP2 isoform-specific antibody reveals the endogenous MeCP2E1 expression in murine brain, primary neurons and astrocytes.
Volume: 7
Issue: 11
Pages: e49763
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Publication
27097329 | J:251790
First Author: Cobolli Gigli C
Year: 2016
Journal: PLoS One
Title: MeCP2 Related Studies Benefit from the Use of CD1 as Genetic Background.
Volume: 11
Issue: 4
Pages: e0153473
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Publication
20716963 | J:323730
First Author: Urdinguio RG
Year: 2010
Journal: Epigenetics
Title: Disrupted microRNA expression caused by Mecp2 loss in a mouse model of Rett syndrome.
Volume: 5
Issue: 7
Pages: 656-63
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Publication
32383329 | J:323738
First Author: Frasca A
Year: 2020
Journal: EMBO Mol Med
Title: MECP2 mutations affect ciliogenesis: a novel perspective for Rett syndrome and related disorders.
Volume: 12
Issue: 6
Pages: e10270
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Publication
28857161 | J:250553
First Author: Lee LJ
Year: 2017
Journal: J Comp Neurol
Title: Structural and functional differences in the barrel cortex of Mecp2 null mice.
Volume: 525
Issue: 18
Pages: 3951-3961
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Publication
29621262 | J:261164
First Author: Balakrishnan S
Year: 2018
Journal: PLoS One
Title: Rescue of hyperexcitability in hippocampal CA1 neurons from Mecp2 (-/y) mouse through surface potential neutralization.
Volume: 13
Issue: 4
Pages: e0195094
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Publication
31138832 | J:323506
First Author: Steinkellner H
Year: 2019
Journal: Sci Rep
Title: An electrochemiluminescence based assay for quantitative detection of endogenous and exogenously applied MeCP2 protein variants.
Volume: 9
Issue: 1
Pages: 7929
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Publication
18834926 | J:143308
First Author: Roux JC
Year: 2008
Journal: Neurosci Lett
Title: Tyrosine hydroxylase deficit in the chemoafferent and the sympathoadrenergic pathways of the Mecp2 deficient mouse.
Volume: 447
Issue: 1
Pages: 82-6
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Publication
21829232 | J:234600
First Author: Kerr B
Year: 2012
Journal: Eur J Hum Genet
Title: Transgenic complementation of MeCP2 deficiency: phenotypic rescue of Mecp2-null mice by isoform-specific transgenes.
Volume: 20
Issue: 1
Pages: 69-76
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Publication
27323888 | J:323663
 
First Author: Stefanelli G
Year: 2016
Journal: Sci Rep
Title: Brain phosphorylation of MeCP2 at serine 164 is developmentally regulated and globally alters its chromatin association.
Volume: 6
Pages: 28295
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Publication
35091041 | J:323678
 
First Author: Ribeiro MC
Year: 2022
Journal: Neurobiol Dis
Title: Vitamin D modulates cortical transcriptome and behavioral phenotypes in an Mecp2 heterozygous Rett syndrome mouse model.
Volume: 165
Pages: 105636
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Publication
22865604 | J:194651
First Author: Yazdani M
Year: 2012
Journal: Stem Cells
Title: Disease modeling using embryonic stem cells: MeCP2 regulates nuclear size and RNA synthesis in neurons.
Volume: 30
Issue: 10
Pages: 2128-39
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Publication
32652084 | J:323672
 
First Author: Villani C
Year: 2020
Journal: Neuropharmacology
Title: Fluoxetine rescues rotarod motor deficits in Mecp2 heterozygous mouse model of Rett syndrome via brain serotonin.
Volume: 176
Pages: 108221
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Publication
18223199 | J:135351
First Author: Jugloff DG
Year: 2008
Journal: Hum Mol Genet
Title: Targeted delivery of an Mecp2 transgene to forebrain neurons improves the behavior of female Mecp2-deficient mice.
Volume: 17
Issue: 10
Pages: 1386-96
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Publication
33665914 | J:313869
First Author: Scaramuzza L
Year: 2021
Journal: EMBO Mol Med
Title: The enhancement of activity rescues the establishment of Mecp2 null neuronal phenotypes.
Volume: 13
Issue: 4
Pages: e12433
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Publication
22615490 | J:186652
First Author: Gonzales ML
Year: 2012
Journal: Mol Cell Biol
Title: Phosphorylation of distinct sites in MeCP2 modifies cofactor associations and the dynamics of transcriptional regulation.
Volume: 32
Issue: 14
Pages: 2894-903
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Publication
32420873 | J:290313
   
First Author: Zhang Y
Year: 2020
Journal: Elife
Title: MeCP2 in cholinergic interneurons of nucleus accumbens regulates fear learning.
Volume: 9
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Publication
23659895 | J:197982
 
First Author: Wang IT
Year: 2013
Journal: Neurobiol Dis
Title: Neuronal morphology in MeCP2 mouse models is intrinsically variable and depends on age, cell type, and Mecp2 mutation.
Volume: 58
Pages: 3-12
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Publication
17701895 | J:134837
First Author: Schüle B
Year: 2007
Journal: Am J Hum Genet
Title: DLX5 and DLX6 expression is biallelic and not modulated by MeCP2 deficiency.
Volume: 81
Issue: 3
Pages: 492-506
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Publication
19414073 | J:226599
First Author: O'Connor RD
Year: 2009
Journal: Bone
Title: Mecp2 deficiency decreases bone formation and reduces bone volume in a rodent model of Rett syndrome.
Volume: 45
Issue: 2
Pages: 346-56
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Publication
17997046 | J:130772
First Author: Russell JC
Year: 2007
Journal: Neuroscience
Title: Enhanced cell death in MeCP2 null cerebellar granule neurons exposed to excitotoxicity and hypoxia.
Volume: 150
Issue: 3
Pages: 563-74
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Publication
34895132 | J:323741
First Author: Abellán-Álvaro M
Year: 2021
Journal: J Neurodev Disord
Title: MeCP2 haplodeficiency and early-life stress interaction on anxiety-like behavior in adolescent female mice.
Volume: 13
Issue: 1
Pages: 59
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Publication
31784358 | J:286255
First Author: Boxer LD
Year: 2020
Journal: Mol Cell
Title: MeCP2 Represses the Rate of Transcriptional Initiation of Highly Methylated Long Genes.
Volume: 77
Issue: 2
Pages: 294-309.e9
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