Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Mittal P |
Year: |
2015 |
Journal: |
J Clin Invest |
Title: |
Med12 gain-of-function mutation causes leiomyomas and genomic instability. |
Volume: |
125 |
Issue: |
8 |
Pages: |
3280-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang S |
Year: |
2012 |
Journal: |
Cell |
Title: |
MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling. |
Volume: |
151 |
Issue: |
5 |
Pages: |
937-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tutter AV |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Role for Med12 in regulation of Nanog and Nanog target genes. |
Volume: |
284 |
Issue: |
6 |
Pages: |
3709-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rocha PP |
Year: |
2010 |
Journal: |
Birth Defects Res A Clin Mol Teratol |
Title: |
Mosaic expression of Med12 in female mice leads to exencephaly, spina bifida, and craniorachischisis. |
Volume: |
88 |
Issue: |
8 |
Pages: |
626-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang TW |
Year: |
2021 |
Journal: |
J Neurosci |
Title: |
Glial-Specific Deletion of Med12 Results in Rapid Hearing Loss via Degradation of the Stria Vascularis. |
Volume: |
41 |
Issue: |
34 |
Pages: |
7171-7181 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baskin KK |
Year: |
2017 |
Journal: |
JCI Insight |
Title: |
MED12 regulates a transcriptional network of calcium-handling genes in the heart. |
Volume: |
2 |
Issue: |
14 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kim NH |
Year: |
2016 |
Journal: |
BMC Dev Biol |
Title: |
Mediator subunit Med12 contributes to the maintenance of neural stem cell identity. |
Volume: |
16 |
Issue: |
1 |
Pages: |
17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang X |
Year: |
2017 |
Journal: |
Biol Reprod |
Title: |
Med12 regulates ovarian steroidogenesis, uterine development and maternal effects in the mammalian egg. |
Volume: |
97 |
Issue: |
6 |
Pages: |
822-834 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aranda-Orgilles B |
Year: |
2016 |
Journal: |
Cell Stem Cell |
Title: |
MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis. |
Volume: |
19 |
Issue: |
6 |
Pages: |
784-799 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rocha PP |
Year: |
2010 |
Journal: |
Development |
Title: |
Med12 is essential for early mouse development and for canonical Wnt and Wnt/PCP signaling. |
Volume: |
137 |
Issue: |
16 |
Pages: |
2723-31 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177789 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6190776 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Med12 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177789 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6190776 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Med12 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177789 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190776 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Med12 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177789 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6190776 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Med12 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177789 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6190776 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Med12 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177789 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190776 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Med12 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6177789 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190776 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Med12 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shin CH |
Year: |
2008 |
Journal: |
Dev Biol |
Title: |
Multiple roles for Med12 in vertebrate endoderm development. |
Volume: |
317 |
Issue: |
2 |
Pages: |
467-79 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
715
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Thomas-Claudepierre AS |
Year: |
2016 |
Journal: |
J Exp Med |
Title: |
Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination. |
Volume: |
213 |
Issue: |
3 |
Pages: |
303-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vogl MR |
Year: |
2013 |
Journal: |
J Neurosci |
Title: |
Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia. |
Volume: |
33 |
Issue: |
15 |
Pages: |
6679-90 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Philibert RA |
Year: |
1998 |
Journal: |
Mol Psychiatry |
Title: |
Association of an X-chromosome dodecamer insertional variant allele with mental retardation. |
Volume: |
3 |
Issue: |
4 |
Pages: |
303-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Duboule D |
Year: |
1987 |
Journal: |
Mol Cell Biol |
Title: |
DNA sequences homologous to the Drosophila opa repeat are present in murine mRNAs that are differentially expressed in fetuses and adult tissues. |
Volume: |
7 |
Issue: |
5 |
Pages: |
2003-6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7314462 |
Assay Type: |
Western blot |
Annotation Date: |
2022-07-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610517 |
|
Stage: |
TS17 |
Assay Id: |
MGI:7314644 |
Age: |
embryonic day 10.5 |
Image: |
2 |
|
Specimen Label: |
Ctrl |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7314462 |
Assay Type: |
Western blot |
Annotation Date: |
2022-07-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610517 |
|
Stage: |
TS17 |
Assay Id: |
MGI:7314644 |
Age: |
embryonic day 10.5 |
Image: |
2 |
|
Specimen Label: |
cKO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7314462 |
Assay Type: |
Western blot |
Annotation Date: |
2022-07-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610519 |
|
Stage: |
TS19 |
Assay Id: |
MGI:7314658 |
Age: |
embryonic day 11.5 |
Image: |
S3 |
|
Specimen Label: |
Ctrl |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7314462 |
Assay Type: |
Western blot |
Annotation Date: |
2022-07-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610519 |
|
Stage: |
TS19 |
Assay Id: |
MGI:7314658 |
Age: |
embryonic day 11.5 |
Image: |
S3 |
|
Specimen Label: |
cKO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7645708 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-06-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1718522 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7645808 |
Age: |
embryonic day 14.5 |
Image: |
3 |
|
Specimen Label: |
E14.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7645708 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-06-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1718526 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7645808 |
Age: |
embryonic day 18.5 |
Image: |
3 |
|
Specimen Label: |
E18.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7645708 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-06-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1718528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7645808 |
Age: |
postnatal day 5 |
Image: |
3 |
|
Specimen Label: |
P5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7645708 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-06-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1718528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7645808 |
Age: |
postnatal day 40 |
Image: |
3 |
|
Specimen Label: |
P40 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7645708 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-06-09 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3586628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7645817 |
Age: |
postnatal month 3 |
Image: |
6 |
|
Specimen Label: |
3 mon |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7645708 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-06-09 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3586628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7645817 |
Age: |
postnatal month 24 |
Image: |
6 |
|
Specimen Label: |
24 mon |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7645749 |
Assay Type: |
Western blot |
Annotation Date: |
2024-06-09 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3586628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7645831 |
Age: |
postnatal month 3 |
Image: |
6 |
|
Specimen Label: |
3 mon |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7645749 |
Assay Type: |
Western blot |
Annotation Date: |
2024-06-09 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3586628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7645831 |
Age: |
postnatal month 24 |
Image: |
6 |
|
Specimen Label: |
24 mon |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7645708 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-06-09 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3586628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7645853 |
Age: |
postnatal week 8-10 |
Image: |
7 |
|
Specimen Label: |
Wt |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7645708 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-06-09 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3586628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7645853 |
Age: |
postnatal week 8-10 |
Image: |
7 |
|
Specimen Label: |
mdx |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li N |
Year: |
2014 |
Journal: |
Nat Cell Biol |
Title: |
Cyclin C is a haploinsufficient tumour suppressor. |
Volume: |
16 |
Issue: |
11 |
Pages: |
1080-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ge K |
Year: |
2002 |
Journal: |
Nature |
Title: |
Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis. |
Volume: |
417 |
Issue: |
6888 |
Pages: |
563-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Malik S |
Year: |
2004 |
Journal: |
Mol Cell Biol |
Title: |
Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors. |
Volume: |
24 |
Issue: |
18 |
Pages: |
8244-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kolonay DW |
Year: |
2024 |
Journal: |
Front Cell Dev Biol |
Title: |
Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease. |
Volume: |
12 |
|
Pages: |
1331563 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ishihara T |
Year: |
2015 |
Journal: |
Mol Cell Biol |
Title: |
Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development. |
Volume: |
35 |
Issue: |
1 |
Pages: |
211-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tan C |
Year: |
2021 |
Journal: |
PLoS Genet |
Title: |
Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network. |
Volume: |
17 |
Issue: |
9 |
Pages: |
e1009785 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kagey MH |
Year: |
2010 |
Journal: |
Nature |
Title: |
Mediator and cohesin connect gene expression and chromatin architecture. |
Volume: |
467 |
Issue: |
7314 |
Pages: |
430-5 |
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2010 |
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Mouse Genome Informatics Scientific Curators |
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Neuron |
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First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
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First Author: |
Helmholtz Zentrum Muenchen GmbH |
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2010 |
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MGI Direct Data Submission |
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Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
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The Gene Ontology Consortium |
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2014 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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DDB, FB, MGI, GOA, ZFIN curators |
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2001 |
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Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
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PLoS Biol |
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BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
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Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
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Title: |
MGI Sequence Curation Reference |
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Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
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MGD Nomenclature Committee |
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2011 |
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Nature |
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A conditional knockout resource for the genome-wide study of mouse gene function. |
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474 |
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GOA curators |
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2016 |
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Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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The Gene Ontology Consortium |
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2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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PLoS Biol |
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Mouse Genome Informatics Scientific Curators |
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2010 |
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Mouse Genome Database and National Center for Biotechnology Information |
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Allen Institute for Brain Science |
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Allen Institute |
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Allen Brain Atlas: mouse riboprobes |
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Mouse Genome Informatics Scientific Curators |
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2009 |
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Database Download |
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Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
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Database Download |
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Mouse Genome Informatics Group |
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Database Procedure |
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Mouse Genome Informatics Scientific Curators |
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2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Mouse Genome Informatics |
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2010 |
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Mouse Genome Informatics Scientific Curators |
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2005 |
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Obtaining and loading genome assembly coordinates from NCBI annotations |
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Mouse Genome Informatics Scientific Curators |
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2009 |
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Database Download |
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Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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