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Search results 1 to 96 out of 96 for Med8

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Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
112950 | MED8
Type: gene
Organism: human
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Gene
100615212 | MED8
Type: gene
Organism: chimpanzee
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Gene
424565 | MED8
Type: gene
Organism: chicken
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Gene
404615 | med8
Type: gene
Organism: zebrafish
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Gene
700676 | MED8
Type: gene
Organism: macaque, rhesus
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Gene
549368 | med8
Type: gene
Organism: frog, western clawed
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Gene
362575 | Med8
Type: gene
Organism: rat
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Gene
610777 | MED8
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1915269 | Med8
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
107984947 | MED8-AS1
Type: gene
Organism: human
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Publication
19624305 | J:150942
First Author: Frankel WN
Year: 2009
Journal: Genes Brain Behav
Title: Szt2, a novel gene for seizure threshold in mice.
Volume: 8
Issue: 5
Pages: 568-76
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Protein Coding Gene
MGP_CAROLIEiJ_G0026373 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028666 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028627 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028577 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028648 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0028362 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1915269 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029089 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027796 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0028329 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0028477 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0028445 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0028579 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0028472 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0029126 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0027522 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027875 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028704 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0027345 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:4437749
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437810
Age: postnatal adult
Specimen Label: wild-type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4437749
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437810
Age: postnatal adult
Specimen Label: Szt2m1Frk
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7314471
Assay Type: Western blot
Annotation Date: 2022-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610517
Stage: TS17
Assay Id: MGI:7314651
Age: embryonic day 10.5
Image: 2
Specimen Label: Ctrl
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7314471
Assay Type: Western blot
Annotation Date: 2022-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610517
Stage: TS17
Assay Id: MGI:7314651
Age: embryonic day 10.5
Image: 2
Specimen Label: cKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:1520358
Assay Type: RNA in situ
Annotation Date: 2011-03-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754422
Stage: TS22
Assay Id: MGI:4940739
Age: embryonic day 14.5
Specimen Label: Table 3 V14.5
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4415953
Assay Type: RNA in situ
Annotation Date: 2011-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4940856
Age: embryonic day 14.5
Specimen Label: Table 3 G14.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4885426
Assay Type: RNA in situ
Annotation Date: 2011-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:4941037
Age: embryonic day 15.5
Specimen Label: Table 3 B15
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1520358
Assay Type: RNA in situ
Annotation Date: 2011-03-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691322
Stage: TS22
Assay Id: MGI:4940739
Age: embryonic day 14.5
Note: Expression is absent in the ventricular and subventricular zones.
Specimen Label: Table 3 V14.5
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4415953
Assay Type: RNA in situ
Annotation Date: 2011-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:4940856
Age: embryonic day 14.5
Note: Expression is in the ventricular zone and is absent in the subventricular zone.
Specimen Label: Table 3 G14.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4885426
Assay Type: RNA in situ
Annotation Date: 2011-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691323
Stage: TS23
Assay Id: MGI:4941037
Age: embryonic day 15.5
Note: Absent in the ventricular and subventricular zones.
Specimen Label: Table 3 B15
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:1520358
Assay Type: RNA in situ
Annotation Date: 2011-03-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691122
Stage: TS22
Assay Id: MGI:4940739
Age: embryonic day 14.5
Specimen Label: Table 3 V14.5
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4415953
Assay Type: RNA in situ
Annotation Date: 2011-03-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691122
Stage: TS22
Assay Id: MGI:4940856
Age: embryonic day 14.5
Specimen Label: Table 3 G14.5
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4885426
Assay Type: RNA in situ
Annotation Date: 2011-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691123
Stage: TS23
Assay Id: MGI:4941037
Age: embryonic day 15.5
Specimen Label: Table 3 B15
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:1520358
Assay Type: RNA in situ
Annotation Date: 2011-03-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:4940739
Age: embryonic day 14.5
Specimen Label: Table 3 V14.5
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4415953
Assay Type: RNA in situ
Annotation Date: 2011-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4940856
Age: embryonic day 14.5
Specimen Label: Table 3 G14.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4885426
Assay Type: RNA in situ
Annotation Date: 2011-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:4941037
Age: embryonic day 15.5
Specimen Label: Table 3 B15
Detected: false
Specimen Num: 1
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Publication
- | J:68268
   
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, similar to hypothetical protein MNCb-2386, clone IMAGE: 3593140, mRNA, partial cds
Pages: BC002315
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Publication
- | J:67420
   
First Author: Osada N
Year: 2000
Journal: GenBank Submission
Title: Mus musculus brain cDNA, clone MNCb-2386, similar to CG13867 gene product (Drosophila melanogaster)
Pages: AB041805
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Publication
24882805 | J:215933
First Author: Tsai KL
Year: 2014
Journal: Cell
Title: Subunit architecture and functional modular rearrangements of the transcriptional mediator complex.
Volume: 157
Issue: 6
Pages: 1430-44
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Publication
14638676 | J:88488
First Author: Tomomori-Sato C
Year: 2004
Journal: J Biol Chem
Title: A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2.
Volume: 279
Issue: 7
Pages: 5846-51
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Publication
11559591 | J:320035
First Author: Mittler G
Year: 2001
Journal: EMBO Rep
Title: Novel critical role of a human Mediator complex for basal RNA polymerase II transcription.
Volume: 2
Issue: 9
Pages: 808-13
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Publication
34506481 | J:309620
First Author: Tan C
Year: 2021
Journal: PLoS Genet
Title: Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network.
Volume: 17
Issue: 9
Pages: e1009785
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Publication
20508642 | J:162104
First Author: Krebs AR
Year: 2010
Journal: EMBO Rep
Title: ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.
Volume: 11
Issue: 7
Pages: 541-7
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Publication
21122108 | J:166749
 
First Author: Hammock EA
Year: 2010
Journal: Neural Dev
Title: Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain.
Volume: 5
Pages: 32
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Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q9CY05
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: false
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Protein
Q9DAY7
Organism: Mus musculus/domesticus
Length: 234  
Fragment?: false
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Protein
A2A9C6
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: true
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Protein
A2A9C8
Organism: Mus musculus/domesticus
Length: 129  
Fragment?: false
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Publication
12584197 | J:114799
First Author: Sato S
Year: 2003
Journal: J Biol Chem
Title: Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3.
Volume: 278
Issue: 17
Pages: 15123-7
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Publication
20194623 | J:161701
First Author: Grøntved L
Year: 2010
Journal: Mol Cell Biol
Title: MED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor gamma and is required for full transcriptional activity and adipogenesis.
Volume: 30
Issue: 9
Pages: 2155-69
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Protein
Q9CZ82
Organism: Mus musculus/domesticus
Length: 208  
Fragment?: false
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Protein
A8Y5Q6
Organism: Mus musculus/domesticus
Length: 122  
Fragment?: true
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Publication
16964259 | -
First Author: Larivière L
Year: 2006
Journal: Nat Struct Mol Biol
Title: Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
Volume: 13
Issue: 10
Pages: 895-901
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Protein Domain
IPR019095 | Mediator_Med18
Type: Family
Description: The Mediator complex is a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. On recruitment the Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins. The Mediator complex is composed of at least 31 subunits: MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The subunits form at least three structurally distinct submodules. The head and the middle modules interact directly with RNA polymerase II, whereas the elongated tail module interacts with gene-specific regulatory proteins. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation.The head module contains: MED6, MED8, MED11, SRB4/MED17, SRB5/MED18, ROX3/MED19, SRB2/MED20 and SRB6/MED22. The middle module contains: MED1, MED4, NUT1/MED5, MED7, CSE2/MED9, NUT2/MED10, SRB7/MED21 and SOH1/MED31. CSE2/MED9 interacts directly with MED4. The tail module contains: MED2, PGD1/MED3, RGR1/MED14, GAL11/MED15 and SIN4/MED16. The CDK8 module contains: MED12, MED13, CCNC and CDK8. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.Med18 is one subunit of the Mediator complex and a component of the head module that is involved in stimulating basal RNA polymerase II (PolII) transcription. Med18 consists of an eight-stranded β-barrel with a central pore and three flanking helices. It complexes with Med8 and Med20 proteins by forming a heterodimer of two-fold symmetry with Med20 and binding the C-terminal α-helix region of Med8 across the top of its barrel. This complex creates a multipartite TBP-binding site that can be modulated by transcriptional activators [].
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Protein
Q9D7W5
Organism: Mus musculus/domesticus
Length: 268  
Fragment?: false
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Protein Domain
IPR019364 | Mediatior_Med8_fun/met
Type: Family
Description: The Mediator complex is a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependentgenes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. On recruitment the Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins. The Mediator complex is composed of at least 31 subunits: MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The subunits form at least three structurally distinct submodules. The head and the middle modules interact directly with RNA polymerase II, whereas the elongated tail module interacts with gene-specific regulatory proteins. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation.The head module contains: MED6, MED8, MED11, SRB4/MED17, SRB5/MED18, ROX3/MED19, SRB2/MED20 and SRB6/MED22. The middle module contains: MED1, MED4, NUT1/MED5, MED7, CSE2/MED9, NUT2/MED10, SRB7/MED21 and SOH1/MED31. CSE2/MED9 interacts directly with MED4. The tail module contains: MED2, PGD1/MED3, RGR1/MED14, GAL11/MED15 and SIN4/MED16. The CDK8 module contains: MED12, MED13, CCNC and CDK8. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.Arc32, or Med8, is one of the subunits of the Mediator complex of RNA polymerase II. The region conserved contains two alpha helices putatively necessary for binding to other subunits within the core of the Mediator complex. The N terminus of Med8 binds to the essential core Head part of Mediator and the C terminus hinges to Med18 on the non-essential part of the Head that also includes Med20 [].
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Publication
18381891 | -
First Author: Larivière L
Year: 2008
Journal: Genes Dev
Title: Structure-system correlation identifies a gene regulatory Mediator submodule.
Volume: 22
Issue: 7
Pages: 872-7
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