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Search results 1 to 94 out of 94 for Mei4

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Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
568897 | mei4
Type: gene
Organism: zebrafish
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Gene
101928601 | MEI4
Type: gene
Organism: human
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Gene
100496694 | mei4
Type: gene
Organism: frog, western clawed
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Gene
104006922 | MEI4
Type: gene
Organism: chimpanzee
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Protein Domain
IPR025888 | MEI4
Type: Family
Description: Meiosis-specific protein MEI4 is required for meiotic induction of recombination, viable spore production and chromosome synapsis. It is a component of the MER2-MEI4-REC114 complex which seems to be required for meiotic double-strand break (DSB) formation [, ]. In Schizosaccharomyces pombe it is known as Rec24 [, ].
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Gene
679805 | Mei4
Type: gene
Organism: rat
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Gene
100429859 | MEI4
Type: gene
Organism: macaque, rhesus
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Gene
101748468 | MEI4
Type: gene
Organism: chicken
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Gene
101902979 | MEI4
Type: gene
Organism: cattle
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Gene
102153459 | MEI4
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1922283 | Mei4
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
20551173 | J:161203
First Author: Kumar R
Year: 2010
Journal: Genes Dev
Title: Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice.
Volume: 24
Issue: 12
Pages: 1266-80
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Protein
Q8BRM6
Organism: Mus musculus/domesticus
Length: 389  
Fragment?: false
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Protein
A0A087WP18
Organism: Mus musculus/domesticus
Length: 290  
Fragment?: false
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Publication
16783010 | -
First Author: Li J
Year: 2006
Journal: Genetics
Title: Saccharomyces cerevisiae Mer2, Mei4 and Rec114 form a complex required for meiotic double-strand break formation.
Volume: 173
Issue: 4
Pages: 1969-81
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Publication
25795304 | J:231710
First Author: Kumar R
Year: 2015
Journal: J Cell Sci
Title: MEI4 – a central player in the regulation of meiotic DNA double-strand break formation in the mouse.
Volume: 128
Issue: 9
Pages: 1800-11
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Publication
21429938 | -
First Author: Bonfils S
Year: 2011
Journal: J Cell Sci
Title: Functional interactions of Rec24, the fission yeast ortholog of mouse Mei4, with the meiotic recombination-initiation complex.
Volume: 124
Issue: Pt 8
Pages: 1328-38
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Protein
Q3TM14
Organism: Mus musculus/domesticus
Length: 328  
Fragment?: true
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Publication
27723721 | J:238496
First Author: Stanzione M
Year: 2016
Journal: Nat Cell Biol
Title: Meiotic DNA break formation requires the unsynapsed chromosome axis-binding protein IHO1 (CCDC36) in mice.
Volume: 18
Issue: 11
Pages: 1208-1220
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Publication
16303567 | -
First Author: Martín-Castellanos C
Year: 2005
Journal: Curr Biol
Title: A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.
Volume: 15
Issue: 22
Pages: 2056-62
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Publication
38657614 | J:348407
First Author: Biot M
Year: 2024
Journal: Mol Cell
Title: Principles of chromosome organization for meiotic recombination.
Volume: 84
Issue: 10
Pages: 1826-1841.e5
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Publication
32461690 | J:291185
First Author: Acquaviva L
Year: 2020
Journal: Nature
Title: Ensuring meiotic DNA break formation in the mouse pseudoautosomal region.
Volume: 582
Issue: 7812
Pages: 426-431
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Publication
30569039 | J:271216
First Author: Kumar R
Year: 2018
Journal: Life Sci Alliance
Title: Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4.
Volume: 1
Issue: 6
Pages: e201800259
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Protein Coding Gene
MGP_CAROLIEiJ_G0032482 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035082 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035063 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034991 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035051 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034763 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1922283 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035574 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034081 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034736 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034894 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034837 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034975 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034879 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035595 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033785 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0034198 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015348 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033621 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:5800308
Assay Type: Immunohistochemistry
Annotation Date: 2016-10-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5800306
Age: postnatal day 30
Specimen Label: 5C +/+ Leptotene
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5800308
Assay Type: Immunohistochemistry
Annotation Date: 2016-10-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5800306
Age: postnatal day 30
Specimen Label: 5C +/+ Zygotene
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5800308
Assay Type: Immunohistochemistry
Annotation Date: 2016-10-11
Strength: Absent
Sex: Male
Emaps: EMAPS:3148428
Stage: TS28
Assay Id: MGI:5800306
Age: postnatal day 30
Specimen Label: 5C +/+ Pachytene
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5800308
Assay Type: Immunohistochemistry
Annotation Date: 2016-10-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5800306
Age: postnatal day 30
Note: Localization was similar in mutant and wild type at leptotene.
Specimen Label: 5C -/- Leptotene
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5800308
Assay Type: Immunohistochemistry
Annotation Date: 2016-10-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5800306
Age: postnatal day 30
Note: Expression was persistent in mutant zygotene-like stages.
Specimen Label: 5C -/- Zygotene Like
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:5800308
Assay Type: Immunohistochemistry
Annotation Date: 2016-10-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5800306
Age: postnatal day 30
Note: Expression was persistent in mutant zygotene-like stages.
Specimen Label: 5C -/- Zygotene Like
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5800308
Assay Type: Immunohistochemistry
Annotation Date: 2016-10-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5800306
Age: postnatal month 8
Specimen Label: S17C +/+ Leptotene
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:5800308
Assay Type: Immunohistochemistry
Annotation Date: 2016-10-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5800306
Age: postnatal month 8
Specimen Label: S17C +/+ Zygotene
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:5800308
Assay Type: Immunohistochemistry
Annotation Date: 2016-10-11
Strength: Absent
Sex: Male
Emaps: EMAPS:3148428
Stage: TS28
Assay Id: MGI:5800306
Age: postnatal month 8
Specimen Label: S17C +/+ Pachytene
Detected: false
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:5800308
Assay Type: Immunohistochemistry
Annotation Date: 2016-10-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5800306
Age: postnatal month 8
Specimen Label: S17C -/- Leptotene
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:5800308
Assay Type: Immunohistochemistry
Annotation Date: 2016-10-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5800306
Age: postnatal month 8
Note: Expression was persistent in mutant zygotene-like stages.
Specimen Label: S17C -/- Zygo. Like
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:5800308
Assay Type: Immunohistochemistry
Annotation Date: 2016-10-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5800306
Age: postnatal month 8
Note: Expression was persistent in mutant zygotene-like stages.
Specimen Label: S17C -/- Zygo Like
Detected: true
Specimen Num: 12
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Publication
31000436 | J:276412
First Author: Papanikos F
Year: 2019
Journal: Mol Cell
Title: Mouse ANKRD31 Regulates Spatiotemporal Patterning of Meiotic Recombination Initiation and Ensures Recombination between X and Y Sex Chromosomes.
Volume: 74
Issue: 5
Pages: 1069-1085.e11
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Publication
26917764 | J:229524
First Author: Robert T
Year: 2016
Journal: Science
Title: The TopoVIB-Like protein family is required for meiotic DNA double-strand break formation.
Volume: 351
Issue: 6276
Pages: 943-9
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Publication
27072294 | J:230563
 
First Author: Kato Y
Year: 2016
Journal: Nat Commun
Title: Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells.
Volume: 7
Pages: 11272
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Publication
35489071 | J:325094
First Author: Guan Y
Year: 2022
Journal: Nucleic Acids Res
Title: SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination.
Volume: 50
Issue: 9
Pages: 5129-5144
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: Meiosis-specific protein MEI4
Type: chain
End: 389
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Protein
Q8BRM6-2
Organism: Mus musculus/domesticus
Length: 312  
Fragment?: false
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Interaction Experiment
Kumar R (2010)
Description: Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice.
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Protein
D3Z3K2
Organism: Mus musculus/domesticus
Length: 276  
Fragment?: false
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Protein Coding Gene
MGI:2685134 | Ccnb1ip1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9CWH4
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
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Protein
A0A087WPF6
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
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Protein Domain
IPR029168 | REC114L
Type: Family
Description: REC114-like is necessary for meiotic DNA double-strand break formation. It works in conjunction with Mei4 []. This family of proteins is found in eukaryotes.
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Protein
Q6PDM4
Organism: Mus musculus/domesticus
Length: 574  
Fragment?: false
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Protein Domain
IPR031529 | IHO1
Type: Family
Description: Interactor of HORMAD1 protein 1 (IHO1, previously known as coiled-coil domain-containing protein 36 or DUF4700) is required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. It is thought to function, in collaboration with SPO11-auxiliary proteins MEI4 and REC114, through the formation of DSB-promoting recombinosomes on chromatin at the onset of meiosis [].
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Publication
17784788 | J:125220
First Author: Ward JO
Year: 2007
Journal: PLoS Genet
Title: Mutation in mouse hei10, an e3 ubiquitin ligase, disrupts meiotic crossing over.
Volume: 3
Issue: 8
Pages: e139
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Publication
28708824 | J:243410
First Author: Crichton JH
Year: 2017
Journal: PLoS Genet
Title: Tex19.1 promotes Spo11-dependent meiotic recombination in mouse spermatocytes.
Volume: 13
Issue: 7
Pages: e1006904
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom